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The map label for this gene is benK [H]

Identifier: 73541308

GI number: 73541308

Start: 1739176

End: 1740552

Strand: Direct

Name: benK [H]

Synonym: Reut_A1618

Alternate gene names: 73541308

Gene position: 1739176-1740552 (Clockwise)

Preceding gene: 73541307

Following gene: 73541309

Centisome position: 45.69

GC content: 56.86

Gene sequence:

>1377_bases
GTGAACGAAAGAAACAACGGGCGAAATATTGACTTACTGAAAATCGCGGACGACGCGAAATTCAATTCCTTCCACGTATC
GATTCTGGCGTGGTGCGCACTGGTCATCATATTTGACGGATATGACCTTGCAGTCTCCGGTATTGCGTTGCCATCCATCA
TGAAAGACATGAATGTCGACGCTACCCGGGCCGGCATGATGGTTAGCTCGGCACTATTTGGGGCAATGTGCGGTGCGGTG
TTGCTGGGGTCCCTGGCCGACCGCATCGGGCGGCGTCGTGCCATTGCGCTTTGCGTGTCCTTGTTCAGTGTGTTTACCGC
AGCGGCTGGCCTGGCCAGCGACCCGATTGCCTTTGGCATTGCGCGCTTTATTGCCGGAATCGGGATTGGCGGGGTGATGC
CGGCGGTCGTGGCGCAGATGACCGAGTATTCCCCGCGCAGGTGGAAGACGACGTTGGTGACGGTGATGTTCAGCGGCTAC
TCTGTCGGAGGCATGATTGCCGCCATGTTTGGCAAGGGCTTCATAGGGACCTATGGCTGGCAAGCCGTCTTCTATGCTGC
GGCAGCGCCGGTATTGGTGGTTCCCTGGATCTTGAAATATGTTCCGGAATCGCTTTCCTACCTGGTCAAGCACAATCGCA
CGAAGGAGTTGAGCCGGATTTGTGCGCGGCTGGATGGCACCTATGTACTTCGCCATGATGATGCGTTCGTCATTGGCGCC
AACCGAAGCGGCGGGACCACGTTGCGCACGCTTTTCGGCGACGGCAGGGGCGTGAGCACCTTCATGTTCTGGATCGTGTT
CTTCATGTGCCTGTTCATGGTTTACGCGTTGAGCTCATGGCTGGCAAAGCTCATGGCCAACGCCGGGTATAGCCTCGGAT
CGGCGCTGACGTTCGTCCTCATTCTGAATATCGGTGGAATCTTCGGCGCGGTTGGTGGAGGCATGCTTGCAGACCGCATG
AACATACGCACTGTGCTTGTCTTCATGTTTGCGCTGGCGGGGGCATCGATTGCACTGTTGGGCTTCAAGTCATCAACGCC
AGTGCTGTATTTCCTTCTGTTTGTAGCCGGTGCGTCGACGATTGGCACGCAGATCGTCGTCTACGCTTATGCGGGTCAGT
ATTATCCCTTGACGATTCGATCGACCGGTATCGGCGTGGGTTCGGGCGTCGGGCGGATTGGCGCCATCTCGGCGCCGGTC
ATCCTTGGCACCGTGGTCGGCATGCAACTTCCGTTGCATCAAAATTTTCTGCTGATGGCAATTCCGGCTGCCATAGCAAT
GATTGCCGTTGCCTTTATTGACCGCTCCAATAGTTCGCCTTCAATCCGTGCAACGGATCTGGAGCCGCGGGCTGACGCTG
CACGCCTGCAGACTTGA

Upstream 100 bases:

>100_bases
ATCGAGGAATCCCTAAGTTGAAAAACGATGTTGACTTCAACATTGAAGTCATATTGTGGATTCCTTTTGCATGCAGTCTG
CATTACAGCAGGAGACAAAG

Downstream 100 bases:

>100_bases
TCCGCGAGCACGATGCGGGTTGCTCGCTCTGGTGTCCATCAATGTCCGCAACGATTCTCACGTTACCAGCGGACACGAGA
TAACAAATAATGTCAGCGAA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MNERNNGRNIDLLKIADDAKFNSFHVSILAWCALVIIFDGYDLAVSGIALPSIMKDMNVDATRAGMMVSSALFGAMCGAV
LLGSLADRIGRRRAIALCVSLFSVFTAAAGLASDPIAFGIARFIAGIGIGGVMPAVVAQMTEYSPRRWKTTLVTVMFSGY
SVGGMIAAMFGKGFIGTYGWQAVFYAAAAPVLVVPWILKYVPESLSYLVKHNRTKELSRICARLDGTYVLRHDDAFVIGA
NRSGGTTLRTLFGDGRGVSTFMFWIVFFMCLFMVYALSSWLAKLMANAGYSLGSALTFVLILNIGGIFGAVGGGMLADRM
NIRTVLVFMFALAGASIALLGFKSSTPVLYFLLFVAGASTIGTQIVVYAYAGQYYPLTIRSTGIGVGSGVGRIGAISAPV
ILGTVVGMQLPLHQNFLLMAIPAAIAMIAVAFIDRSNSSPSIRATDLEPRADAARLQT

Sequences:

>Translated_458_residues
MNERNNGRNIDLLKIADDAKFNSFHVSILAWCALVIIFDGYDLAVSGIALPSIMKDMNVDATRAGMMVSSALFGAMCGAV
LLGSLADRIGRRRAIALCVSLFSVFTAAAGLASDPIAFGIARFIAGIGIGGVMPAVVAQMTEYSPRRWKTTLVTVMFSGY
SVGGMIAAMFGKGFIGTYGWQAVFYAAAAPVLVVPWILKYVPESLSYLVKHNRTKELSRICARLDGTYVLRHDDAFVIGA
NRSGGTTLRTLFGDGRGVSTFMFWIVFFMCLFMVYALSSWLAKLMANAGYSLGSALTFVLILNIGGIFGAVGGGMLADRM
NIRTVLVFMFALAGASIALLGFKSSTPVLYFLLFVAGASTIGTQIVVYAYAGQYYPLTIRSTGIGVGSGVGRIGAISAPV
ILGTVVGMQLPLHQNFLLMAIPAAIAMIAVAFIDRSNSSPSIRATDLEPRADAARLQT
>Mature_458_residues
MNERNNGRNIDLLKIADDAKFNSFHVSILAWCALVIIFDGYDLAVSGIALPSIMKDMNVDATRAGMMVSSALFGAMCGAV
LLGSLADRIGRRRAIALCVSLFSVFTAAAGLASDPIAFGIARFIAGIGIGGVMPAVVAQMTEYSPRRWKTTLVTVMFSGY
SVGGMIAAMFGKGFIGTYGWQAVFYAAAAPVLVVPWILKYVPESLSYLVKHNRTKELSRICARLDGTYVLRHDDAFVIGA
NRSGGTTLRTLFGDGRGVSTFMFWIVFFMCLFMVYALSSWLAKLMANAGYSLGSALTFVLILNIGGIFGAVGGGMLADRM
NIRTVLVFMFALAGASIALLGFKSSTPVLYFLLFVAGASTIGTQIVVYAYAGQYYPLTIRSTGIGVGSGVGRIGAISAPV
ILGTVVGMQLPLHQNFLLMAIPAAIAMIAVAFIDRSNSSPSIRATDLEPRADAARLQT

Specific function: Probable uptake of benzoate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI7662270, Length=226, Percent_Identity=28.7610619469027, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI24308167, Length=420, Percent_Identity=21.9047619047619, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI216548223, Length=180, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI262399383, Length=167, Percent_Identity=29.3413173652695, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI73695465, Length=241, Percent_Identity=23.6514522821577, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI203098995, Length=197, Percent_Identity=26.9035532994924, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI24497476, Length=426, Percent_Identity=23.4741784037559, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI20070188, Length=419, Percent_Identity=23.6276849642005, Blast_Score=66, Evalue=5e-11,
Organism=Homo sapiens, GI213021148, Length=431, Percent_Identity=21.5777262180974, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87081723, Length=379, Percent_Identity=30.0791556728232, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87082159, Length=400, Percent_Identity=30.5, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1786229, Length=391, Percent_Identity=25.0639386189258, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI87082231, Length=445, Percent_Identity=23.3707865168539, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082404, Length=375, Percent_Identity=24, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788074, Length=421, Percent_Identity=22.3277909738717, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI32564663, Length=435, Percent_Identity=20.6896551724138, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI19922874, Length=439, Percent_Identity=22.0956719817768, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24640198, Length=230, Percent_Identity=24.3478260869565, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640196, Length=230, Percent_Identity=24.3478260869565, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24640200, Length=230, Percent_Identity=24.3478260869565, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48683; Mature: 48683

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: PS00120 LIPASE_SER ; PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERNNGRNIDLLKIADDAKFNSFHVSILAWCALVIIFDGYDLAVSGIALPSIMKDMNVD
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
ATRAGMMVSSALFGAMCGAVLLGSLADRIGRRRAIALCVSLFSVFTAAAGLASDPIAFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ARFIAGIGIGGVMPAVVAQMTEYSPRRWKTTLVTVMFSGYSVGGMIAAMFGKGFIGTYGW
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCHHHHHHHHHCCCCCCHHHH
QAVFYAAAAPVLVVPWILKYVPESLSYLVKHNRTKELSRICARLDGTYVLRHDDAFVIGA
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCEEEEEC
NRSGGTTLRTLFGDGRGVSTFMFWIVFFMCLFMVYALSSWLAKLMANAGYSLGSALTFVL
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILNIGGIFGAVGGGMLADRMNIRTVLVFMFALAGASIALLGFKSSTPVLYFLLFVAGAST
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHH
IGTQIVVYAYAGQYYPLTIRSTGIGVGSGVGRIGAISAPVILGTVVGMQLPLHQNFLLMA
HCCEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
IPAAIAMIAVAFIDRSNSSPSIRATDLEPRADAARLQT
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHCCCC
>Mature Secondary Structure
MNERNNGRNIDLLKIADDAKFNSFHVSILAWCALVIIFDGYDLAVSGIALPSIMKDMNVD
CCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
ATRAGMMVSSALFGAMCGAVLLGSLADRIGRRRAIALCVSLFSVFTAAAGLASDPIAFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
ARFIAGIGIGGVMPAVVAQMTEYSPRRWKTTLVTVMFSGYSVGGMIAAMFGKGFIGTYGW
HHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHEEEEECCCCHHHHHHHHHCCCCCCHHHH
QAVFYAAAAPVLVVPWILKYVPESLSYLVKHNRTKELSRICARLDGTYVLRHDDAFVIGA
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEECCEEEEEC
NRSGGTTLRTLFGDGRGVSTFMFWIVFFMCLFMVYALSSWLAKLMANAGYSLGSALTFVL
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ILNIGGIFGAVGGGMLADRMNIRTVLVFMFALAGASIALLGFKSSTPVLYFLLFVAGAST
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCHH
IGTQIVVYAYAGQYYPLTIRSTGIGVGSGVGRIGAISAPVILGTVVGMQLPLHQNFLLMA
HCCEEEEEEECCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHH
IPAAIAMIAVAFIDRSNSSPSIRATDLEPRADAARLQT
HHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9294456 [H]