Click here to switch to the map view.

The map label for this gene is melR [C]

Identifier: 73541307

GI number: 73541307

Start: 1738003

End: 1739037

Strand: Direct

Name: melR [C]

Synonym: Reut_A1617

Alternate gene names: 73541307

Gene position: 1738003-1739037 (Clockwise)

Preceding gene: 73541306

Following gene: 73541308

Centisome position: 45.66

GC content: 55.85

Gene sequence:

>1035_bases
ATGAAAACCGCAGCTGTCCTGGTGTTTCCCGAAGTTCAAGGCCTGGATGTCTCCGGGCCGCTTGATGTCTTTGCGGAAGC
CAATCGCTTTCTTTCTTCGGAAGACCAGTATTCCTTTGAAATTCTTGGAACTGAACCGGGACGGATACGTTGCTCCAATG
GACTGGAAATCCACCCGGATCGCTTGTTTTCTGAATCCAATGGCGCCTATGAGCTATTGCTTATCGCCGGAGGACCCACG
TTGCCTCAACAGAGCTTTGCGCCTTCCCTATATGCATGGATCCGGTCGGCGTCTGTCAATTCAGCATGCATTTGCACAAT
CTGTAACGGCACCTTCCTGTTGGCCAGAGCCGGTGTCCTCGATGGCAAGCATGTCACGACCCACTGGAATGATGCGGCGA
GCCTTGCCCGGGAGTGTCCAACGGCCGTGGTGAGCCCTGACAGGCTGTATATCCAGGACGGCAATCTGGTGACATCCGCA
GGCGTGACGGCCGGCATCGACATGAGCCTCTATCTGCTGGCAAGAGACCATGGCCGGGAGGTAGCCATCCAAGTTGCCAA
GCAGTTGTTGCTCTTTACGCATCGCGCAGGGGGCCAGTCACAGTTCAGCCCTTACCTCAATACATCGGTAGAGCCCAGTT
CATTGGTTTCGCGCGTGCACGAGTACGTGTTTGCCAATTTGACCGCGGACCTGTCGCTGAACGTTCTCGCGAACGTCGCG
AGAATGAGCGTGCGCCACTTCACGCGGATTTTCATGCGCGAGTCCAACATCAGTGTGATGGACTTTGTCGAAGCCGTACG
GCTGGACGCTGCCAGAAGCTTGCTTGAGACAACATCCAGGCCGATCAAGGCAATCGCCTATGAGTGTGGCTTTTCCACGG
CACACCGAATGCGTTCGGTATTTCGAAGAAACCTGGGCATTTCACCGCAGGACTATCGCGCGCACTTCCTGGATCCGGCG
TCTGGCTCACGGCAGCTCCCTGATTTCCCGGCACGAGACCAAAAAAACCATCGCCATACGCTGATCAACGCCTGA

Upstream 100 bases:

>100_bases
CGGCTGCGGCGGATGCGACGGCGTCAGGCTCCGCGTTCTAAAGGCTGATGACAAGAGGCCAAAAGGTGGAAAGTGCGTTA
TCCGATTTACCGACGTTGAC

Downstream 100 bases:

>100_bases
AAAATAGTCCTTCTCGTCAGGGACGGTGAGGCATCCGGATCGAGGAATCCCTAAGTTGAAAAACGATGTTGACTTCAACA
TTGAAGTCATATTGTGGATT

Product: transcriptional regulator

Products: NA

Alternate protein names: ORF1 [H]

Number of amino acids: Translated: 344; Mature: 344

Protein sequence:

>344_residues
MKTAAVLVFPEVQGLDVSGPLDVFAEANRFLSSEDQYSFEILGTEPGRIRCSNGLEIHPDRLFSESNGAYELLLIAGGPT
LPQQSFAPSLYAWIRSASVNSACICTICNGTFLLARAGVLDGKHVTTHWNDAASLARECPTAVVSPDRLYIQDGNLVTSA
GVTAGIDMSLYLLARDHGREVAIQVAKQLLLFTHRAGGQSQFSPYLNTSVEPSSLVSRVHEYVFANLTADLSLNVLANVA
RMSVRHFTRIFMRESNISVMDFVEAVRLDAARSLLETTSRPIKAIAYECGFSTAHRMRSVFRRNLGISPQDYRAHFLDPA
SGSRQLPDFPARDQKNHRHTLINA

Sequences:

>Translated_344_residues
MKTAAVLVFPEVQGLDVSGPLDVFAEANRFLSSEDQYSFEILGTEPGRIRCSNGLEIHPDRLFSESNGAYELLLIAGGPT
LPQQSFAPSLYAWIRSASVNSACICTICNGTFLLARAGVLDGKHVTTHWNDAASLARECPTAVVSPDRLYIQDGNLVTSA
GVTAGIDMSLYLLARDHGREVAIQVAKQLLLFTHRAGGQSQFSPYLNTSVEPSSLVSRVHEYVFANLTADLSLNVLANVA
RMSVRHFTRIFMRESNISVMDFVEAVRLDAARSLLETTSRPIKAIAYECGFSTAHRMRSVFRRNLGISPQDYRAHFLDPA
SGSRQLPDFPARDQKNHRHTLINA
>Mature_344_residues
MKTAAVLVFPEVQGLDVSGPLDVFAEANRFLSSEDQYSFEILGTEPGRIRCSNGLEIHPDRLFSESNGAYELLLIAGGPT
LPQQSFAPSLYAWIRSASVNSACICTICNGTFLLARAGVLDGKHVTTHWNDAASLARECPTAVVSPDRLYIQDGNLVTSA
GVTAGIDMSLYLLARDHGREVAIQVAKQLLLFTHRAGGQSQFSPYLNTSVEPSSLVSRVHEYVFANLTADLSLNVLANVA
RMSVRHFTRIFMRESNISVMDFVEAVRLDAARSLLETTSRPIKAIAYECGFSTAHRMRSVFRRNLGISPQDYRAHFLDPA
SGSRQLPDFPARDQKNHRHTLINA

Specific function: Transcription Activator For The Expression Of The Melab Operon. Melr Binds At Two Sites Located Upstream Of The Melab Transcription Site. [C]

COG id: COG4977

COG function: function code K; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 37828; Mature: 37828

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTAAVLVFPEVQGLDVSGPLDVFAEANRFLSSEDQYSFEILGTEPGRIRCSNGLEIHPD
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCEECHH
RLFSESNGAYELLLIAGGPTLPQQSFAPSLYAWIRSASVNSACICTICNGTFLLARAGVL
HHHCCCCCCEEEEEEECCCCCCCHHCCHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCC
DGKHVTTHWNDAASLARECPTAVVSPDRLYIQDGNLVTSAGVTAGIDMSLYLLARDHGRE
CCCEEEECCCHHHHHHHHCCCCEECCCEEEEECCCEEEECCCEECCCEEEEEEECCCCHH
VAIQVAKQLLLFTHRAGGQSQFSPYLNTSVEPSSLVSRVHEYVFANLTADLSLNVLANVA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RMSVRHFTRIFMRESNISVMDFVEAVRLDAARSLLETTSRPIKAIAYECGFSTAHRMRSV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHH
FRRNLGISPQDYRAHFLDPASGSRQLPDFPARDQKNHRHTLINA
HHHHCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCEEECCC
>Mature Secondary Structure
MKTAAVLVFPEVQGLDVSGPLDVFAEANRFLSSEDQYSFEILGTEPGRIRCSNGLEIHPD
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCCEECHH
RLFSESNGAYELLLIAGGPTLPQQSFAPSLYAWIRSASVNSACICTICNGTFLLARAGVL
HHHCCCCCCEEEEEEECCCCCCCHHCCHHHHHHHHCCCCCCEEEEEEECCEEEEEECCCC
DGKHVTTHWNDAASLARECPTAVVSPDRLYIQDGNLVTSAGVTAGIDMSLYLLARDHGRE
CCCEEEECCCHHHHHHHHCCCCEECCCEEEEECCCEEEECCCEECCCEEEEEEECCCCHH
VAIQVAKQLLLFTHRAGGQSQFSPYLNTSVEPSSLVSRVHEYVFANLTADLSLNVLANVA
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
RMSVRHFTRIFMRESNISVMDFVEAVRLDAARSLLETTSRPIKAIAYECGFSTAHRMRSV
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHH
FRRNLGISPQDYRAHFLDPASGSRQLPDFPARDQKNHRHTLINA
HHHHCCCCCCCCHHEECCCCCCCCCCCCCCCCCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8157602 [H]