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The map label for this gene is ybdL [H]

Identifier: 73540715

GI number: 73540715

Start: 1100891

End: 1102063

Strand: Reverse

Name: ybdL [H]

Synonym: Reut_A1012

Alternate gene names: 73540715

Gene position: 1102063-1100891 (Counterclockwise)

Preceding gene: 73540716

Following gene: 73540713

Centisome position: 28.95

GC content: 64.62

Gene sequence:

>1173_bases
ATGTCCGCAGACTCCACCCTCGCCCCGCTGACTCCGCCCGTGTCGCGCCTACCATCCGTCGGCACCACGATCTTCACCGT
GATGTCCGCACTGGCAGCCGAAAAGAACGCCGTCAACCTCGGACAGGGCTTTCCCGACTTCGATTGCGATCCGCGCATCG
TCGATGCCGTGACCCATGCCATGCGCACGGGTCACAACCAGTACCCGCCGATGGCCGGCGTGCCGCGCCTGCGCCAGGCA
ATCGCCGACAAGATCGCCACGCTGTACGGCCATCGCTATAGCTGGGAAAGCGAGATCACCGTCACGGCCGGCGCCACGCA
GGGCATCCTGACCGCGATCCTGTGCGCCGTGCATCCCGGCGACGAGGTGATCGTGCTGGAACCGTGCTACGACAGCTACC
TGCCGGCGATCGAACTGGCCGGCGCGACCGCTGTGCCGGTCACGCTGGAGGCGCCCGATTTCCGCGTGCCGTTCGACCGC
CTCGCTGCTGCCATCACGCCGCGTACGCGGATGATCCTCATCAACACGCCGCACAACCCGACCGGGACGATCTGGCGTGC
CGCCGACATGGACAAGCTGGCCCAACTGCTGGCCGGCACCGACATCCTGCTGCTGTCGGACGAGGTCTACGAGCACATGG
TCTACGACAGAGAGCCACACGCATCGGTGTCACGCCATCCGGAACTTGCGCGGCGCAGCTTCGTGATTTCGAGCTTCGGC
AAGACCTACCACGTGACGGGCTGGAAGGTCGGTTATGTGGCGGCGCCGGCGGCGCTATCGGCGGAATTCCGCAAGGTGCA
CCAGTTCAACGTGTTCACCGTGAATACGCCCGTACAGCATGGCCTGGCCGACTACATGGCCGATCCCGCGCCGTATCTGG
AACTCTCCGCGTTCTACCAGGCCAAGCGCGACTATTTCCGCGCCGGGTTGGCCAATACGCGTTTCAAGCTGCTGCCGTCC
GAGGGCACGTATTTCCAATGCGTGGACTACTCCGCGATTTCCGACCTGAGCGAGGCCGAGTTTTCGATGTGGCTGACGCG
AGAGATCGGCGTGGCGGCGATCCCGGTCTCGGCCTTCTATACGCAGCCGCGCGAATCGGGCGTGGTGCGATTCTGCTTCG
CCAAGAAGGAAGAAACGCTGTCGCGGGCATTGGAGCGGCTGGCAAAGCTCTGA

Upstream 100 bases:

>100_bases
GCCCTGGCGGCCGCCGCCTGATGCCTCGAATCGCTTTAGAATTGCCGCTGTTGCCGCTTCGGCAAGCCGATTTTCGCTCT
CGTCCTACAACGTCGCAGCC

Downstream 100 bases:

>100_bases
AATCGGTCCCGCCAATACGAGAACGCAAGAACGCCCGCGGCATGTGTGTGCCGCGGGCGTTTTGCTTCATGCGCAGTACC
CATGCAGGCCGGCGCTTACT

Product: putative aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSADSTLAPLTPPVSRLPSVGTTIFTVMSALAAEKNAVNLGQGFPDFDCDPRIVDAVTHAMRTGHNQYPPMAGVPRLRQA
IADKIATLYGHRYSWESEITVTAGATQGILTAILCAVHPGDEVIVLEPCYDSYLPAIELAGATAVPVTLEAPDFRVPFDR
LAAAITPRTRMILINTPHNPTGTIWRAADMDKLAQLLAGTDILLLSDEVYEHMVYDREPHASVSRHPELARRSFVISSFG
KTYHVTGWKVGYVAAPAALSAEFRKVHQFNVFTVNTPVQHGLADYMADPAPYLELSAFYQAKRDYFRAGLANTRFKLLPS
EGTYFQCVDYSAISDLSEAEFSMWLTREIGVAAIPVSAFYTQPRESGVVRFCFAKKEETLSRALERLAKL

Sequences:

>Translated_390_residues
MSADSTLAPLTPPVSRLPSVGTTIFTVMSALAAEKNAVNLGQGFPDFDCDPRIVDAVTHAMRTGHNQYPPMAGVPRLRQA
IADKIATLYGHRYSWESEITVTAGATQGILTAILCAVHPGDEVIVLEPCYDSYLPAIELAGATAVPVTLEAPDFRVPFDR
LAAAITPRTRMILINTPHNPTGTIWRAADMDKLAQLLAGTDILLLSDEVYEHMVYDREPHASVSRHPELARRSFVISSFG
KTYHVTGWKVGYVAAPAALSAEFRKVHQFNVFTVNTPVQHGLADYMADPAPYLELSAFYQAKRDYFRAGLANTRFKLLPS
EGTYFQCVDYSAISDLSEAEFSMWLTREIGVAAIPVSAFYTQPRESGVVRFCFAKKEETLSRALERLAKL
>Mature_389_residues
SADSTLAPLTPPVSRLPSVGTTIFTVMSALAAEKNAVNLGQGFPDFDCDPRIVDAVTHAMRTGHNQYPPMAGVPRLRQAI
ADKIATLYGHRYSWESEITVTAGATQGILTAILCAVHPGDEVIVLEPCYDSYLPAIELAGATAVPVTLEAPDFRVPFDRL
AAAITPRTRMILINTPHNPTGTIWRAADMDKLAQLLAGTDILLLSDEVYEHMVYDREPHASVSRHPELARRSFVISSFGK
TYHVTGWKVGYVAAPAALSAEFRKVHQFNVFTVNTPVQHGLADYMADPAPYLELSAFYQAKRDYFRAGLANTRFKLLPSE
GTYFQCVDYSAISDLSEAEFSMWLTREIGVAAIPVSAFYTQPRESGVVRFCFAKKEETLSRALERLAKL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=32.2738386308068, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=32.2738386308068, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=33.1670822942643, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI56713256, Length=402, Percent_Identity=33.0845771144279, Blast_Score=208, Evalue=8e-54,
Organism=Homo sapiens, GI169881281, Length=407, Percent_Identity=28.5012285012285, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4507369, Length=218, Percent_Identity=24.3119266055046, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=52.7704485488127, Blast_Score=405, Evalue=1e-114,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=24.2819843342037, Blast_Score=111, Evalue=9e-26,
Organism=Escherichia coli, GI1788627, Length=229, Percent_Identity=28.82096069869, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1787710, Length=414, Percent_Identity=27.7777777777778, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787909, Length=130, Percent_Identity=29.2307692307692, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71994476, Length=425, Percent_Identity=34.5882352941176, Blast_Score=234, Evalue=6e-62,
Organism=Caenorhabditis elegans, GI71994472, Length=425, Percent_Identity=34.5882352941176, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI17567369, Length=405, Percent_Identity=31.8518518518519, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17567663, Length=337, Percent_Identity=21.3649851632047, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322401, Length=397, Percent_Identity=29.4710327455919, Blast_Score=188, Evalue=2e-48,
Organism=Drosophila melanogaster, GI28573069, Length=409, Percent_Identity=33.4963325183374, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24646114, Length=409, Percent_Identity=33.4963325183374, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI28573067, Length=409, Percent_Identity=33.4963325183374, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI28573065, Length=409, Percent_Identity=33.4963325183374, Blast_Score=223, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42904; Mature: 42773

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADSTLAPLTPPVSRLPSVGTTIFTVMSALAAEKNAVNLGQGFPDFDCDPRIVDAVTHA
CCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRTGHNQYPPMAGVPRLRQAIADKIATLYGHRYSWESEITVTAGATQGILTAILCAVHPG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCC
DEVIVLEPCYDSYLPAIELAGATAVPVTLEAPDFRVPFDRLAAAITPRTRMILINTPHNP
CCEEEECCCCCCCCCHHHCCCCEECEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCC
TGTIWRAADMDKLAQLLAGTDILLLSDEVYEHMVYDREPHASVSRHPELARRSFVISSFG
CCCEEECCCHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
KTYHVTGWKVGYVAAPAALSAEFRKVHQFNVFTVNTPVQHGLADYMADPAPYLELSAFYQ
CEEEECCEEEEEEECCHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHH
AKRDYFRAGLANTRFKLLPSEGTYFQCVDYSAISDLSEAEFSMWLTREIGVAAIPVSAFY
HHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHH
TQPRESGVVRFCFAKKEETLSRALERLAKL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SADSTLAPLTPPVSRLPSVGTTIFTVMSALAAEKNAVNLGQGFPDFDCDPRIVDAVTHA
CCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRTGHNQYPPMAGVPRLRQAIADKIATLYGHRYSWESEITVTAGATQGILTAILCAVHPG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHCCCC
DEVIVLEPCYDSYLPAIELAGATAVPVTLEAPDFRVPFDRLAAAITPRTRMILINTPHNP
CCEEEECCCCCCCCCHHHCCCCEECEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCC
TGTIWRAADMDKLAQLLAGTDILLLSDEVYEHMVYDREPHASVSRHPELARRSFVISSFG
CCCEEECCCHHHHHHHHCCCCEEEECHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCC
KTYHVTGWKVGYVAAPAALSAEFRKVHQFNVFTVNTPVQHGLADYMADPAPYLELSAFYQ
CEEEECCEEEEEEECCHHHHHHHHHHHEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHH
AKRDYFRAGLANTRFKLLPSEGTYFQCVDYSAISDLSEAEFSMWLTREIGVAAIPVSAFY
HHHHHHHHCCCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEEEEHHHHH
TQPRESGVVRFCFAKKEETLSRALERLAKL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]