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The map label for this gene is qorA [H]

Identifier: 73540661

GI number: 73540661

Start: 1046673

End: 1047677

Strand: Direct

Name: qorA [H]

Synonym: Reut_A0958

Alternate gene names: 73540661

Gene position: 1046673-1047677 (Clockwise)

Preceding gene: 73540660

Following gene: 73540662

Centisome position: 27.5

GC content: 64.88

Gene sequence:

>1005_bases
ATGCAAGCCATCGAGATTCGCGAATACGGTGCCCCCGAGGTCCTGCAGGAGACGCAGCGTCCCGACCCGGTGCCGGGTGC
CGGCGAAATCCTGATCCGTGTGGCCGCGGCTGGCGTCAACCGTCCGGACGTGTTTCAGCGTACCGGCAACTATCCGGTGC
CGCCAGGCGCGTCGGATCTGCCGGGCCTGGAAGTGGCTGGCGTGGTTGTCGGTGGTGACCTGTCCCATGCCGACAACCGC
TTCGGCCTGAAGGTCGGCGATCGCGTGTGCGCACTCGTGCAGGGCGGTGGCTATGCGCAACTCTGCACCGCCCCGGTGGC
GCAATGCCTGCCGGCCCCAAAGGGCCTGAGTGATATTGAAGCCGCTGCGCTGCCGGAGACGTTCTTCACCGTCTGGAGCA
ATGTGTTCGATCGCGGCTATCTGGGCCAGGGCCCGCGCGGCAAGGACGAGACGCTGCTGATCCAGGGCGGTTCGAGCGGC
ATCGGCACGACCGCGATCCAGATTGCCAAGGCGCTCGGCTACAAGGTGTTCGTCACGGCTGGTACGGACGAGAAGTGCAA
GGCTTGCGAGGACCTCGGCGCCGATCGCGCGATCAACTACAAGACTCAGGATTTCGTTGCCGAAGTCGCGTCGCTGACCG
AGGGCAAGGGCGTCGACGTGATCCTCGATATGGTGGCTGGCTCCTATCTCGCGCGCGAGCTGAAGTGCATTGCCGATGAT
GGCCGTATCGTCATCATCGCGCTGCTTGGCGGCGCCAAGGCGGAAATTCCGCTCGGCGACATTCTGCGCCGCCGTATCAC
CGTCACCGGTTCGACGCTGCGTCCGCGCTCCGCGTCGTTCAAGGGGCAGATTGCGCAGGCACTGCACCAGCAGGTGTGGC
CGCTGCTCGAAGCCGGCAAGATCAAGCCCGTGATCCACAAGGTTTTCCCGGCGGCGCAGGCCGCCGAAGCGCATCGTCTG
ATGGAATCGAGCGAACACATCGGCAAGATCGTGCTGACCTGGTAA

Upstream 100 bases:

>100_bases
TTTTTGTTTACACTGCCGGGCAACCCATTGAGCAATCGCTCTTCCCGAAGCGCCGCGACAGCGTCATCGCCTCGCGCACA
GACAAAGACAAGGAGCAGCA

Downstream 100 bases:

>100_bases
TTGCACGAAAAAGTTGCTACCGCGGCCAAGCCGGCCGCGGTAGCGCCGGTCCCCCGCCGCAAGCTACAATAACGGGTTTG
ATTTGGGAGGGGACCTCGTG

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MQAIEIREYGAPEVLQETQRPDPVPGAGEILIRVAAAGVNRPDVFQRTGNYPVPPGASDLPGLEVAGVVVGGDLSHADNR
FGLKVGDRVCALVQGGGYAQLCTAPVAQCLPAPKGLSDIEAAALPETFFTVWSNVFDRGYLGQGPRGKDETLLIQGGSSG
IGTTAIQIAKALGYKVFVTAGTDEKCKACEDLGADRAINYKTQDFVAEVASLTEGKGVDVILDMVAGSYLARELKCIADD
GRIVIIALLGGAKAEIPLGDILRRRITVTGSTLRPRSASFKGQIAQALHQQVWPLLEAGKIKPVIHKVFPAAQAAEAHRL
MESSEHIGKIVLTW

Sequences:

>Translated_334_residues
MQAIEIREYGAPEVLQETQRPDPVPGAGEILIRVAAAGVNRPDVFQRTGNYPVPPGASDLPGLEVAGVVVGGDLSHADNR
FGLKVGDRVCALVQGGGYAQLCTAPVAQCLPAPKGLSDIEAAALPETFFTVWSNVFDRGYLGQGPRGKDETLLIQGGSSG
IGTTAIQIAKALGYKVFVTAGTDEKCKACEDLGADRAINYKTQDFVAEVASLTEGKGVDVILDMVAGSYLARELKCIADD
GRIVIIALLGGAKAEIPLGDILRRRITVTGSTLRPRSASFKGQIAQALHQQVWPLLEAGKIKPVIHKVFPAAQAAEAHRL
MESSEHIGKIVLTW
>Mature_334_residues
MQAIEIREYGAPEVLQETQRPDPVPGAGEILIRVAAAGVNRPDVFQRTGNYPVPPGASDLPGLEVAGVVVGGDLSHADNR
FGLKVGDRVCALVQGGGYAQLCTAPVAQCLPAPKGLSDIEAAALPETFFTVWSNVFDRGYLGQGPRGKDETLLIQGGSSG
IGTTAIQIAKALGYKVFVTAGTDEKCKACEDLGADRAINYKTQDFVAEVASLTEGKGVDVILDMVAGSYLARELKCIADD
GRIVIIALLGGAKAEIPLGDILRRRITVTGSTLRPRSASFKGQIAQALHQQVWPLLEAGKIKPVIHKVFPAAQAAEAHRL
MESSEHIGKIVLTW

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=339, Percent_Identity=37.7581120943953, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI22538444, Length=339, Percent_Identity=37.7581120943953, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI194239674, Length=339, Percent_Identity=31.858407079646, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI13236495, Length=339, Percent_Identity=31.858407079646, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI194239676, Length=339, Percent_Identity=29.4985250737463, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI18379349, Length=319, Percent_Identity=28.2131661442006, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI24308257, Length=350, Percent_Identity=25.4285714285714, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI41872631, Length=323, Percent_Identity=30.3405572755418, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI197927207, Length=184, Percent_Identity=31.5217391304348, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI47519420, Length=360, Percent_Identity=30, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI28557745, Length=282, Percent_Identity=28.0141843971631, Blast_Score=83, Evalue=4e-16,
Organism=Escherichia coli, GI1790485, Length=336, Percent_Identity=30.952380952381, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI226510941, Length=279, Percent_Identity=26.5232974910394, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17507255, Length=337, Percent_Identity=26.7062314540059, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI212642053, Length=323, Percent_Identity=26.625386996904, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319520, Length=344, Percent_Identity=27.3255813953488, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=347, Percent_Identity=24.207492795389, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=292, Percent_Identity=26.027397260274, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323729, Length=347, Percent_Identity=23.9193083573487, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI221330659, Length=284, Percent_Identity=28.5211267605634, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24581345, Length=271, Percent_Identity=28.0442804428044, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI19920632, Length=276, Percent_Identity=28.9855072463768, Blast_Score=95, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35299; Mature: 35299

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIEIREYGAPEVLQETQRPDPVPGAGEILIRVAAAGVNRPDVFQRTGNYPVPPGASDL
CCCEECCCCCCHHHHHHCCCCCCCCCHHHHHEEHHHCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGVVVGGDLSHADNRFGLKVGDRVCALVQGGGYAQLCTAPVAQCLPAPKGLSDIE
CCCEEEEEEEECCCCCCCCCCCEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHH
AAALPETFFTVWSNVFDRGYLGQGPRGKDETLLIQGGSSGIGTTAIQIAKALGYKVFVTA
HHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEC
GTDEKCKACEDLGADRAINYKTQDFVAEVASLTEGKGVDVILDMVAGSYLARELKCIADD
CCCHHHHHHHHCCCCCEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECC
GRIVIIALLGGAKAEIPLGDILRRRITVTGSTLRPRSASFKGQIAQALHQQVWPLLEAGK
CCEEEEEEECCCCCCCCHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
IKPVIHKVFPAAQAAEAHRLMESSEHIGKIVLTW
CCHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEEC
>Mature Secondary Structure
MQAIEIREYGAPEVLQETQRPDPVPGAGEILIRVAAAGVNRPDVFQRTGNYPVPPGASDL
CCCEECCCCCCHHHHHHCCCCCCCCCHHHHHEEHHHCCCCCCHHHHHCCCCCCCCCCCCC
PGLEVAGVVVGGDLSHADNRFGLKVGDRVCALVQGGGYAQLCTAPVAQCLPAPKGLSDIE
CCCEEEEEEEECCCCCCCCCCCEECCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCHHH
AAALPETFFTVWSNVFDRGYLGQGPRGKDETLLIQGGSSGIGTTAIQIAKALGYKVFVTA
HHHCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCEEEEEEC
GTDEKCKACEDLGADRAINYKTQDFVAEVASLTEGKGVDVILDMVAGSYLARELKCIADD
CCCHHHHHHHHCCCCCEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHEECC
GRIVIIALLGGAKAEIPLGDILRRRITVTGSTLRPRSASFKGQIAQALHQQVWPLLEAGK
CCEEEEEEECCCCCCCCHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
IKPVIHKVFPAAQAAEAHRLMESSEHIGKIVLTW
CCHHHHHHCCHHHHHHHHHHHHHHHHHCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]