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The map label for this gene is rpoD [H]

Identifier: 73540591

GI number: 73540591

Start: 967430

End: 969781

Strand: Direct

Name: rpoD [H]

Synonym: Reut_A0888

Alternate gene names: 73540591

Gene position: 967430-969781 (Clockwise)

Preceding gene: 73540590

Following gene: 73540592

Centisome position: 25.41

GC content: 62.5

Gene sequence:

>2352_bases
ATGACAAAGGCCTCGACTTCGGCACGCGAGAGCGGCAAGAGCGCCAGTACGAGCGGCAAGGTCGCCGCATCTGCACCAGT
GAAAGGCAAGAGTATCACCGTGGCGAAACAGCAGAATACCGAAGTCGAAAGCAAGCAGACGGCAGCAGCAGCCGGTGCCA
AGAGCGCAAGCGCCAAGGCAGGTGCGACTGCGCCGGCACCCAAGGCACGCGCCGCTTCTCCCGCCGCCGTTGCATCCGAG
CGTCCCGCAGCGCCGGCAGTCAAGCCGGAACCGAAAAAGCGTGGCCGCAAGCCAAAGGCGGAGTTGCAGCGCGACGAGAG
CACGACTGACGACGTGACTGAAGAGTTCTTCGAGAACGACACGCCCGCAGCGGCGCCTGCCGCCGCGCCGAAGACCGAAA
AGCAGAAGGCCAAGGACCGCAAGGCCAAGGAGAAGGCGCTGCTGAAGGAGTTCGCCTCGACCCAGCAGGGCACGGAGGAA
GAGCTCGAGCTGCGTCGACAGAAGCTCAAGGCGCTGATCAAGCTGGGCAAGTCGCGCGGCTACCTGACCTACGCCGAAAT
CAACGATCACCTGCCGGACGACATGGTCGATTCGGAGACGATCGACACGCTCGTCGCCACCCTGAACGACATCGGCATTG
CCGTGTACGAACAGGCGCCGGACGCCGAAACGCTGCTGCTCAACGACAACGCGCCGTCCGCCACCAGCGAGGAAGAGGCT
GAGGAAGAAGCCGAAGCCGCGCTGTCGACCGTCGACTCCGAATTCGGCCGCACCACCGACCCCGTGCGTATGTACATGCG
CGAAATGGGCACGGTGGAGCTGCTCACGCGCGAAGGCGAAATCGTGATCGCCAAGCGTATCGAGGCGGGCCTGAAGGACA
TGGTGATGGCCATTTCCGCGTGCCCGGTCACGATCTCGGAAATTCTGGCCAACGCCGAGCGCGTCGCCAGCGACGAAATC
AAGATCGACGAATTCGTTGATGGCCTGATCGACCCGAACGCCGATGAAATGGCCCAGGAAGCCGCGGGTGCTTCGGCCGC
GGATGAAGAAGACCTGGAATCCGACGAGGACGAAGAGTCCGACGAGGACGAGGAAGACGACGACGCTGCCGGCGCCGGTG
CCTCGGCACGCCAGCTCGAAGAGCTGAAGCTGTCCGCACTCGAGAAATTCCGCGTCATCGCCGAGCAGTTCGACAAGATG
CGCCGCGCGTTCGAGAAGGAAGGCTATAACTCCAAGCCTTACGTGAAGGCGCAGGAAGCCATCCAGGCCGAGCTGATGGG
CATCCGCTTTACCGCGCGCAGCGTCGAGCGCCTGTGCGACACGCTGCGCGGCCAGGTCGACGAAGTGCGCAAGCTCGAAC
GCTCGATCCTGAATATCGTGGTCGACAAATGCGGCATGCCGCGCTCGGATTTTGTCGCGCGCTTCCCGGGCAACGAAACC
AACCTCGACTGGGTTGGCACCATCGTGGCCGATGGCAAGCCCTACAGCACCATCGTCGAACGCAACGTGCCGGCCGTGCA
TGAACTGCAGCAGAAGCTGATTGACCTGCAATCGCGCGTGGTGCTGCCGCTCAAGGAACTCAAGGGCGTCAACCGCAAGA
TGGCCGAGGGCGAAAAGCGCGCCCGCGAAGCCAAGCGCGAGATGACCGAGGCCAACCTGCGCCTGGTGATCTCGATCGCC
AAGAAGTACACCAACCGCGGCCTGCAGTTCCTCGATCTGATCCAGGAAGGCAACATCGGCCTGATGAAGGCGGTGGACAA
GTTCGAATACCGCCGCGGCTACAAGTTCTCGACGTATGCCACGTGGTGGATCCGCCAGGCCATCACGCGTTCGATCGCCG
ACCAGGCGCGCACCATCCGTATCCCGGTGCACATGATCGAGACGATCAACAAGATGAACCGCATCTCGCGCCAGATCCTG
CAGGAAACCGGCAACGAGCCGGATCCGGCAACGCTGGCCGAGAAGATGGAGATGCCGGAAGACAAGATCCGCAAGATCAT
GAAGATCGCGAAGGAACCGATCTCCATGGAAACGCCGATCGGTGACGACGACGACTCCCATCTGGGCGACTTTATCGAGG
ACACCAACACGCTGGCCCCCGCAGAAGCGGCCCTGCACGGCTCCATGCGCGACGTCGTCAAGGACGTGCTGGACTCGCTG
ACGCCGCGCGAAGCCAAGGTGCTGCGCATGCGCTTCGGCATCGAAATGAGCACCGATCACACGCTGGAAGAGGTCGGCAA
GCAGTTCGACGTCACCCGCGAACGTATCCGCCAGATCGAAGCCAAGGCATTGCGAAAGCTGCGCCACCCGAGCCGCTCTG
ATAAGCTCAAGAGTTTCCTGGAAGGCAACTAA

Upstream 100 bases:

>100_bases
GTCAGTCAAGACTCCGGCCCCCCGGTCTGCGCCATCAAAGCCAGCGCGAGGCGCCGAATCGCCCGCCCTGGCCACTGCCA
CCAGGAATCGCACATCCGAA

Downstream 100 bases:

>100_bases
CGCTTCCAAGGGCCTCTAGCTCATGCCTGGTTAGAGCAGCGGACTCATAATCCGTTGGTGCCGTGTTCGACTCACGGGAG
GCCCACCAATAATGAAGAGG

Product: RNA polymerase sigma factor RpoD

Products: NA

Alternate protein names: Sigma-70 [H]

Number of amino acids: Translated: 783; Mature: 782

Protein sequence:

>783_residues
MTKASTSARESGKSASTSGKVAASAPVKGKSITVAKQQNTEVESKQTAAAAGAKSASAKAGATAPAPKARAASPAAVASE
RPAAPAVKPEPKKRGRKPKAELQRDESTTDDVTEEFFENDTPAAAPAAAPKTEKQKAKDRKAKEKALLKEFASTQQGTEE
ELELRRQKLKALIKLGKSRGYLTYAEINDHLPDDMVDSETIDTLVATLNDIGIAVYEQAPDAETLLLNDNAPSATSEEEA
EEEAEAALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIVIAKRIEAGLKDMVMAISACPVTISEILANAERVASDEI
KIDEFVDGLIDPNADEMAQEAAGASAADEEDLESDEDEESDEDEEDDDAAGAGASARQLEELKLSALEKFRVIAEQFDKM
RRAFEKEGYNSKPYVKAQEAIQAELMGIRFTARSVERLCDTLRGQVDEVRKLERSILNIVVDKCGMPRSDFVARFPGNET
NLDWVGTIVADGKPYSTIVERNVPAVHELQQKLIDLQSRVVLPLKELKGVNRKMAEGEKRAREAKREMTEANLRLVISIA
KKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQIL
QETGNEPDPATLAEKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTLAPAEAALHGSMRDVVKDVLDSL
TPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSFLEGN

Sequences:

>Translated_783_residues
MTKASTSARESGKSASTSGKVAASAPVKGKSITVAKQQNTEVESKQTAAAAGAKSASAKAGATAPAPKARAASPAAVASE
RPAAPAVKPEPKKRGRKPKAELQRDESTTDDVTEEFFENDTPAAAPAAAPKTEKQKAKDRKAKEKALLKEFASTQQGTEE
ELELRRQKLKALIKLGKSRGYLTYAEINDHLPDDMVDSETIDTLVATLNDIGIAVYEQAPDAETLLLNDNAPSATSEEEA
EEEAEAALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIVIAKRIEAGLKDMVMAISACPVTISEILANAERVASDEI
KIDEFVDGLIDPNADEMAQEAAGASAADEEDLESDEDEESDEDEEDDDAAGAGASARQLEELKLSALEKFRVIAEQFDKM
RRAFEKEGYNSKPYVKAQEAIQAELMGIRFTARSVERLCDTLRGQVDEVRKLERSILNIVVDKCGMPRSDFVARFPGNET
NLDWVGTIVADGKPYSTIVERNVPAVHELQQKLIDLQSRVVLPLKELKGVNRKMAEGEKRAREAKREMTEANLRLVISIA
KKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQIL
QETGNEPDPATLAEKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTLAPAEAALHGSMRDVVKDVLDSL
TPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSFLEGN
>Mature_782_residues
TKASTSARESGKSASTSGKVAASAPVKGKSITVAKQQNTEVESKQTAAAAGAKSASAKAGATAPAPKARAASPAAVASER
PAAPAVKPEPKKRGRKPKAELQRDESTTDDVTEEFFENDTPAAAPAAAPKTEKQKAKDRKAKEKALLKEFASTQQGTEEE
LELRRQKLKALIKLGKSRGYLTYAEINDHLPDDMVDSETIDTLVATLNDIGIAVYEQAPDAETLLLNDNAPSATSEEEAE
EEAEAALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIVIAKRIEAGLKDMVMAISACPVTISEILANAERVASDEIK
IDEFVDGLIDPNADEMAQEAAGASAADEEDLESDEDEESDEDEEDDDAAGAGASARQLEELKLSALEKFRVIAEQFDKMR
RAFEKEGYNSKPYVKAQEAIQAELMGIRFTARSVERLCDTLRGQVDEVRKLERSILNIVVDKCGMPRSDFVARFPGNETN
LDWVGTIVADGKPYSTIVERNVPAVHELQQKLIDLQSRVVLPLKELKGVNRKMAEGEKRAREAKREMTEANLRLVISIAK
KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQILQ
ETGNEPDPATLAEKMEMPEDKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTLAPAEAALHGSMRDVVKDVLDSLT
PREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSFLEGN

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=618, Percent_Identity=56.4724919093851, Blast_Score=652, Evalue=0.0,
Organism=Escherichia coli, GI1789098, Length=225, Percent_Identity=41.3333333333333, Blast_Score=203, Evalue=4e-53,
Organism=Escherichia coli, GI1789871, Length=243, Percent_Identity=27.5720164609054, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR007631
- InterPro:   IPR007127
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR012760
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04546 Sigma70_ner; PF03979 Sigma70_r1_1; PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 86567; Mature: 86435

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00715 SIGMA70_1 ; PS00716 SIGMA70_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKASTSARESGKSASTSGKVAASAPVKGKSITVAKQQNTEVESKQTAAAAGAKSASAKA
CCCCCCHHHHCCCCCCCCCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
GATAPAPKARAASPAAVASERPAAPAVKPEPKKRGRKPKAELQRDESTTDDVTEEFFEND
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHCCCCCHHHHHCCCCCHHHHHHHHHCCC
TPAAAPAAAPKTEKQKAKDRKAKEKALLKEFASTQQGTEEELELRRQKLKALIKLGKSRG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
YLTYAEINDHLPDDMVDSETIDTLVATLNDIGIAVYEQAPDAETLLLNDNAPSATSEEEA
CEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCHHHH
EEEAEAALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIVIAKRIEAGLKDMVMAISA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHH
CPVTISEILANAERVASDEIKIDEFVDGLIDPNADEMAQEAAGASAADEEDLESDEDEES
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHCCCCCCCCC
DEDEEDDDAAGAGASARQLEELKLSALEKFRVIAEQFDKMRRAFEKEGYNSKPYVKAQEA
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IQAELMGIRFTARSVERLCDTLRGQVDEVRKLERSILNIVVDKCGMPRSDFVARFPGNET
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCC
NLDWVGTIVADGKPYSTIVERNVPAVHELQQKLIDLQSRVVLPLKELKGVNRKMAEGEKR
CCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHH
AREAKREMTEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHH
TWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQILQETGNEPDPATLAEKMEMPE
HHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCH
DKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTLAPAEAALHGSMRDVVKDVLDSL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
TPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSFL
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EGN
CCC
>Mature Secondary Structure 
TKASTSARESGKSASTSGKVAASAPVKGKSITVAKQQNTEVESKQTAAAAGAKSASAKA
CCCCCHHHHCCCCCCCCCCEEECCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCCC
GATAPAPKARAASPAAVASERPAAPAVKPEPKKRGRKPKAELQRDESTTDDVTEEFFEND
CCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHCCCCCHHHHHCCCCCHHHHHHHHHCCC
TPAAAPAAAPKTEKQKAKDRKAKEKALLKEFASTQQGTEEELELRRQKLKALIKLGKSRG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCC
YLTYAEINDHLPDDMVDSETIDTLVATLNDIGIAVYEQAPDAETLLLNDNAPSATSEEEA
CEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCCCCEEEEECCCCCCCCHHHH
EEEAEAALSTVDSEFGRTTDPVRMYMREMGTVELLTREGEIVIAKRIEAGLKDMVMAISA
HHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHHHHHHHHH
CPVTISEILANAERVASDEIKIDEFVDGLIDPNADEMAQEAAGASAADEEDLESDEDEES
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHCCCCCCCCC
DEDEEDDDAAGAGASARQLEELKLSALEKFRVIAEQFDKMRRAFEKEGYNSKPYVKAQEA
CCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
IQAELMGIRFTARSVERLCDTLRGQVDEVRKLERSILNIVVDKCGMPRSDFVARFPGNET
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHEEECCCCCC
NLDWVGTIVADGKPYSTIVERNVPAVHELQQKLIDLQSRVVLPLKELKGVNRKMAEGEKR
CCCEEEEEEECCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHH
AREAKREMTEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHH
TWWIRQAITRSIADQARTIRIPVHMIETINKMNRISRQILQETGNEPDPATLAEKMEMPE
HHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCH
DKIRKIMKIAKEPISMETPIGDDDDSHLGDFIEDTNTLAPAEAALHGSMRDVVKDVLDSL
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHC
TPREAKVLRMRFGIEMSTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSDKLKSFL
CCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
EGN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA