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The map label for this gene is ygdL [H]

Identifier: 73540521

GI number: 73540521

Start: 889347

End: 890234

Strand: Direct

Name: ygdL [H]

Synonym: Reut_A0818

Alternate gene names: 73540521

Gene position: 889347-890234 (Clockwise)

Preceding gene: 73540515

Following gene: 73540523

Centisome position: 23.36

GC content: 68.02

Gene sequence:

>888_bases
ATGAACGACGCTGCCTCCCCATTGCCCGAACTGCCGCCTCATCTGGCGGATCTGCCCGAACCGCTGACCCACGAAAGCCC
GGCCGATGACGACTATCACCGCCGTTTCGGCGGTGTCGCCCGGCTCTACGGCAACGCCGGGCTCGCGCGCCTTGAGGCGG
CCAGCATTTGCGTGGTGGGCATCGGCGGCGTCGGGAGCTGGACGGCAGAGGCGCTGGCGCGCAATGCCGTCGGCCGCATC
ACGCTGATAGACCTCGACCATATCGCGCTGTCCAACACCAACCGGCAGATCCATGCACTTGGCGATGCCTACGGCCGCGC
CAAGGTAGAGGCCATGGCCGAGCGCATCATGGCGATCAACCCGCGCTGTCGCGTCACGCAGGTCGATGACTTCGTCACCA
CGGACAACGTGGCCCAACTGCTCGGCGCCGGCCACGATTACGTGATCGACGCCATTGATGCGGTGCGCGTCAAGACCGCC
ATGCTGGGCTGGGCGCGCGGCCACGGCATGCCGATCATCACCTGCGGCGGCGCCGGCGGGCAGTTCGACCCGACGCGCGT
GCGCATCGACGATCTGTCCCGTACCATCCAGGATCCGTTGCTGTCCAAGGTTCGCGCGAGCCTGCGCAAGGACTGGGGCT
TTTCGCGTGATCCGAAGAAGAGGTTCGGCATCGCGGCGGTCTATTCGGACGAGCCGCTGCAGTATCCCGAACCCGAACAG
CAGGCCTGCGAGATCGACGAAGCGCCGCCGGCCGCGGCGGTGGCGCCTGCGTCGGGGCCGCAAGGGCTGGCCTGCGCCGG
CTTCGGATCCTCGGTGGCGGTGACAGCGGTGTTCGGGTTCGTCGCGGCTTCCGCCGTGATCGGCGCGATCGCCAGAGGCA
AGCCCTAA

Upstream 100 bases:

>100_bases
GGGAATGGCTGACAGAGCCGCGTGCGCCGTCCTATTTTGCATGCGCGTGCCCGCAAGTTTTTCCGCCCGAATTCAGCCGA
TTTCCAACCCGACTGCCAGC

Downstream 100 bases:

>100_bases
GCGCTCAATGCGCGCAGCAGCGCGTCGGTCTCTGCCTGCTCGGGTGCAAGATTGTTGAAGTAGATGAGTTCCGGGTACTC
GGCCGGTTCCGGCATGAAGC

Product: UBA/THIF-type NAD/FAD binding fold

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNDAASPLPELPPHLADLPEPLTHESPADDDYHRRFGGVARLYGNAGLARLEAASICVVGIGGVGSWTAEALARNAVGRI
TLIDLDHIALSNTNRQIHALGDAYGRAKVEAMAERIMAINPRCRVTQVDDFVTTDNVAQLLGAGHDYVIDAIDAVRVKTA
MLGWARGHGMPIITCGGAGGQFDPTRVRIDDLSRTIQDPLLSKVRASLRKDWGFSRDPKKRFGIAAVYSDEPLQYPEPEQ
QACEIDEAPPAAAVAPASGPQGLACAGFGSSVAVTAVFGFVAASAVIGAIARGKP

Sequences:

>Translated_295_residues
MNDAASPLPELPPHLADLPEPLTHESPADDDYHRRFGGVARLYGNAGLARLEAASICVVGIGGVGSWTAEALARNAVGRI
TLIDLDHIALSNTNRQIHALGDAYGRAKVEAMAERIMAINPRCRVTQVDDFVTTDNVAQLLGAGHDYVIDAIDAVRVKTA
MLGWARGHGMPIITCGGAGGQFDPTRVRIDDLSRTIQDPLLSKVRASLRKDWGFSRDPKKRFGIAAVYSDEPLQYPEPEQ
QACEIDEAPPAAAVAPASGPQGLACAGFGSSVAVTAVFGFVAASAVIGAIARGKP
>Mature_295_residues
MNDAASPLPELPPHLADLPEPLTHESPADDDYHRRFGGVARLYGNAGLARLEAASICVVGIGGVGSWTAEALARNAVGRI
TLIDLDHIALSNTNRQIHALGDAYGRAKVEAMAERIMAINPRCRVTQVDDFVTTDNVAQLLGAGHDYVIDAIDAVRVKTA
MLGWARGHGMPIITCGGAGGQFDPTRVRIDDLSRTIQDPLLSKVRASLRKDWGFSRDPKKRFGIAAVYSDEPLQYPEPEQ
QACEIDEAPPAAAVAPASGPQGLACAGFGSSVAVTAVFGFVAASAVIGAIARGKP

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Escherichia coli, GI1789177, Length=256, Percent_Identity=54.296875, Blast_Score=281, Evalue=4e-77,
Organism=Escherichia coli, GI1787048, Length=143, Percent_Identity=30.0699300699301, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321790, Length=213, Percent_Identity=30.0469483568075, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6322825, Length=187, Percent_Identity=31.5508021390374, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6321903, Length=201, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24582879, Length=140, Percent_Identity=29.2857142857143, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 31082; Mature: 31082

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAASPLPELPPHLADLPEPLTHESPADDDYHRRFGGVARLYGNAGLARLEAASICVVG
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCHHHHHHCEEEEEE
IGGVGSWTAEALARNAVGRITLIDLDHIALSNTNRQIHALGDAYGRAKVEAMAERIMAIN
CCCCCHHHHHHHHHHCCCEEEEEEECCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCC
PRCRVTQVDDFVTTDNVAQLLGAGHDYVIDAIDAVRVKTAMLGWARGHGMPIITCGGAGG
CCCEEEECCCHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
QFDPTRVRIDDLSRTIQDPLLSKVRASLRKDWGFSRDPKKRFGIAAVYSDEPLQYPEPEQ
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEECCCCCCCCCCHH
QACEIDEAPPAAAVAPASGPQGLACAGFGSSVAVTAVFGFVAASAVIGAIARGKP
HHCCCCCCCCCCEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNDAASPLPELPPHLADLPEPLTHESPADDDYHRRFGGVARLYGNAGLARLEAASICVVG
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHCCHHHHHCCCCHHHHHHCEEEEEE
IGGVGSWTAEALARNAVGRITLIDLDHIALSNTNRQIHALGDAYGRAKVEAMAERIMAIN
CCCCCHHHHHHHHHHCCCEEEEEEECCEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHCC
PRCRVTQVDDFVTTDNVAQLLGAGHDYVIDAIDAVRVKTAMLGWARGHGMPIITCGGAGG
CCCEEEECCCHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
QFDPTRVRIDDLSRTIQDPLLSKVRASLRKDWGFSRDPKKRFGIAAVYSDEPLQYPEPEQ
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCEEEEECCCCCCCCCCHH
QACEIDEAPPAAAVAPASGPQGLACAGFGSSVAVTAVFGFVAASAVIGAIARGKP
HHCCCCCCCCCCEECCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]