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The map label for this gene is surA

Identifier: 73540204

GI number: 73540204

Start: 541699

End: 543198

Strand: Direct

Name: surA

Synonym: Reut_A0498

Alternate gene names: 73540204

Gene position: 541699-543198 (Clockwise)

Preceding gene: 73540203

Following gene: 73540205

Centisome position: 14.23

GC content: 66.93

Gene sequence:

>1500_bases
ATGAAACGTCAAGAATTCGCCTTGTTTTCCCTGACCCTGATGTTGTCGCCGTGGCGCCGCGTTCTGCTGCCGGCCGTGCT
CGCGGCCATGGCCGGGCCGGCCCTGGCCCAGCTCAAGGCGCCTTCCCAAGCATCGCGCGCTACAGGCATCTTTGTGCCGC
AATCGTCGGACGTGGCCGTGCCGTCGAGCCAGCCGCAACTCGGCGTGCCGCAGCCCAGCAGCGGCGGCAAGCGTTCGCAA
CTCGTCGATGAAGTGGTCGCGGTGGTCAACAACAGCGTGATCACGCGCCGCGAACTGCTCGACCGTGCCGACGAAATCGA
AGCGCAACTGCGCACCGCCAACCGGCCGGCGCCGCCGCGCGCGGACCTGCTCGGTGAAGTGCTCGAACGCCTGATCATGG
AACGCGTGCAGACCCAGGCCGCGCAGGATGCCGGCATCAAGGTGACTGACCAGGAACTCGACCGCGCAATCGAATCCGTC
GCACAGCAGAACCGCCTGAGCGCGACAGAATTGCGCCGTCGTGTCGAGGCCAGCGGCATGACGTGGACCAAGTATCGCGA
CGAACTGCGCAAGCAGGTGCAGGTGATCCGCCTGCGCGAACGCGAAGTGGATTCAAAGGTACAGGTCTACGACGGCGAAA
TCGACAACTACCTCGCCGCGCGCGGCGGTCAGGGTGCGGCGGCCACCGGGCCGACCGAGTTCAATGTGTCCCAGATCCTC
GTGCGCGTGCCGGAGAATGCCTCCGATGCGCAGAAGCAGGAACTCCAGAAGAAGGCCGAGCAACTGCTCAAGCAGGCGCA
GGGCGGTGCCGACTTCGCCCAGCTCGCGCAAGCAAATTCCCAGGGGCCCGAAGCGGCGCAGGGCGGTGCGATAGGCTTCC
GCGAGATTGGCCGCCTGCCGGCACTGTTCGCCAACGCCGTGGTCGACCTGCAGCCGGGCGCCGTGGCGCCCGAGGTGGTG
GAAAGCGCCAACGGTTTCCACATCCTGAAGCTGACCGCCAAGCGCGTGGCGCCTGCGTCGACATCGGCTTCCAGTCCTGC
CGCGGCTTCCCGCATCACGCAGACTCAGGTCCGCCACATCCTGATCCGTACGGGCCCGAACATGCCCGAAGCCGAGGCGC
GCCGCCAGCTCGGCACCCTGCGTGACCGCATCACGCACGGCGGTGACTTTGCCGACGCCGCCAAGCGCTTCTCGCAGGAC
GGCTCGGCGCAGGCCGGCGGCGAACTGGGCTGGGTTTCGCCCGGTGAACTGGTGCCCGAATTCGAGCAGGCCATGAACCG
GCTGCGCCCCGGCGAGATCTCGGAACCGGTTGTCACGCAGTTCGGCGTGCACCTGATCCAGGTAGAGAACCGCCGCGAGA
CCGAGATGGCACCAGAGAAGCAGCGCGACTTCGCCCGTGCTGAAATCCGCGAGCAGAAGCTGCGCGCGGCCTATGATGAC
TGGGTGCGCCAGCTGCGTTCGCAGGCGTACGTCGAGTACCGCGTCAACCGACAGCGCTGA

Upstream 100 bases:

>100_bases
TCCGCTTGATATCCTGCGCCTGAATGTTCCTGGGTACGAACCTGTCACCGCCAAGCCGGTGCCGACGACCCAGTTTGATC
ACTATGAATGACGGATTACG

Downstream 100 bases:

>100_bases
GGTACCCGCCGCCCCCGCCGCCCCCGCCGCCCCGTAGCACGACCACGACATGCCCGACCCGCTTGCGCTAGCCATTTCTA
CCGGTGAACCCGCCGGTATC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MKRQEFALFSLTLMLSPWRRVLLPAVLAAMAGPALAQLKAPSQASRATGIFVPQSSDVAVPSSQPQLGVPQPSSGGKRSQ
LVDEVVAVVNNSVITRRELLDRADEIEAQLRTANRPAPPRADLLGEVLERLIMERVQTQAAQDAGIKVTDQELDRAIESV
AQQNRLSATELRRRVEASGMTWTKYRDELRKQVQVIRLREREVDSKVQVYDGEIDNYLAARGGQGAAATGPTEFNVSQIL
VRVPENASDAQKQELQKKAEQLLKQAQGGADFAQLAQANSQGPEAAQGGAIGFREIGRLPALFANAVVDLQPGAVAPEVV
ESANGFHILKLTAKRVAPASTSASSPAAASRITQTQVRHILIRTGPNMPEAEARRQLGTLRDRITHGGDFADAAKRFSQD
GSAQAGGELGWVSPGELVPEFEQAMNRLRPGEISEPVVTQFGVHLIQVENRRETEMAPEKQRDFARAEIREQKLRAAYDD
WVRQLRSQAYVEYRVNRQR

Sequences:

>Translated_499_residues
MKRQEFALFSLTLMLSPWRRVLLPAVLAAMAGPALAQLKAPSQASRATGIFVPQSSDVAVPSSQPQLGVPQPSSGGKRSQ
LVDEVVAVVNNSVITRRELLDRADEIEAQLRTANRPAPPRADLLGEVLERLIMERVQTQAAQDAGIKVTDQELDRAIESV
AQQNRLSATELRRRVEASGMTWTKYRDELRKQVQVIRLREREVDSKVQVYDGEIDNYLAARGGQGAAATGPTEFNVSQIL
VRVPENASDAQKQELQKKAEQLLKQAQGGADFAQLAQANSQGPEAAQGGAIGFREIGRLPALFANAVVDLQPGAVAPEVV
ESANGFHILKLTAKRVAPASTSASSPAAASRITQTQVRHILIRTGPNMPEAEARRQLGTLRDRITHGGDFADAAKRFSQD
GSAQAGGELGWVSPGELVPEFEQAMNRLRPGEISEPVVTQFGVHLIQVENRRETEMAPEKQRDFARAEIREQKLRAAYDD
WVRQLRSQAYVEYRVNRQR
>Mature_499_residues
MKRQEFALFSLTLMLSPWRRVLLPAVLAAMAGPALAQLKAPSQASRATGIFVPQSSDVAVPSSQPQLGVPQPSSGGKRSQ
LVDEVVAVVNNSVITRRELLDRADEIEAQLRTANRPAPPRADLLGEVLERLIMERVQTQAAQDAGIKVTDQELDRAIESV
AQQNRLSATELRRRVEASGMTWTKYRDELRKQVQVIRLREREVDSKVQVYDGEIDNYLAARGGQGAAATGPTEFNVSQIL
VRVPENASDAQKQELQKKAEQLLKQAQGGADFAQLAQANSQGPEAAQGGAIGFREIGRLPALFANAVVDLQPGAVAPEVV
ESANGFHILKLTAKRVAPASTSASSPAAASRITQTQVRHILIRTGPNMPEAEARRQLGTLRDRITHGGDFADAAKRFSQD
GSAQAGGELGWVSPGELVPEFEQAMNRLRPGEISEPVVTQFGVHLIQVENRRETEMAPEKQRDFARAEIREQKLRAAYDD
WVRQLRSQAYVEYRVNRQR

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=420, Percent_Identity=34.2857142857143, Blast_Score=226, Evalue=3e-60,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_CUPPJ (Q475Q3)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_294724.1
- HSSP:   P24327
- ProteinModelPortal:   Q475Q3
- SMR:   Q475Q3
- GeneID:   3611802
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0498
- NMPDR:   fig|264198.3.peg.1010
- HOGENOM:   HBG391483
- OMA:   RHILIKT
- ProtClustDB:   CLSK896579
- BioCyc:   REUT264198:REUT_A0498-MONOMER
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 54743; Mature: 54743

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRQEFALFSLTLMLSPWRRVLLPAVLAAMAGPALAQLKAPSQASRATGIFVPQSSDVAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHCCCCEEEECCCCCCCC
PSSQPQLGVPQPSSGGKRSQLVDEVVAVVNNSVITRRELLDRADEIEAQLRTANRPAPPR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ADLLGEVLERLIMERVQTQAAQDAGIKVTDQELDRAIESVAQQNRLSATELRRRVEASGM
HHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
TWTKYRDELRKQVQVIRLREREVDSKVQVYDGEIDNYLAARGGQGAAATGPTEFNVSQIL
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHH
VRVPENASDAQKQELQKKAEQLLKQAQGGADFAQLAQANSQGPEAAQGGAIGFREIGRLP
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ALFANAVVDLQPGAVAPEVVESANGFHILKLTAKRVAPASTSASSPAAASRITQTQVRHI
HHHHHHHHCCCCCCCCHHHHHCCCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LIRTGPNMPEAEARRQLGTLRDRITHGGDFADAAKRFSQDGSAQAGGELGWVSPGELVPE
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
FEQAMNRLRPGEISEPVVTQFGVHLIQVENRRETEMAPEKQRDFARAEIREQKLRAAYDD
HHHHHHHCCCCCCCCHHHHHHCCEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
WVRQLRSQAYVEYRVNRQR
HHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKRQEFALFSLTLMLSPWRRVLLPAVLAAMAGPALAQLKAPSQASRATGIFVPQSSDVAV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHCCCCEEEECCCCCCCC
PSSQPQLGVPQPSSGGKRSQLVDEVVAVVNNSVITRRELLDRADEIEAQLRTANRPAPPR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCH
ADLLGEVLERLIMERVQTQAAQDAGIKVTDQELDRAIESVAQQNRLSATELRRRVEASGM
HHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
TWTKYRDELRKQVQVIRLREREVDSKVQVYDGEIDNYLAARGGQGAAATGPTEFNVSQIL
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHCCCCCCCCCCCCCCCHHHHH
VRVPENASDAQKQELQKKAEQLLKQAQGGADFAQLAQANSQGPEAAQGGAIGFREIGRLP
EECCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
ALFANAVVDLQPGAVAPEVVESANGFHILKLTAKRVAPASTSASSPAAASRITQTQVRHI
HHHHHHHHCCCCCCCCHHHHHCCCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LIRTGPNMPEAEARRQLGTLRDRITHGGDFADAAKRFSQDGSAQAGGELGWVSPGELVPE
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHH
FEQAMNRLRPGEISEPVVTQFGVHLIQVENRRETEMAPEKQRDFARAEIREQKLRAAYDD
HHHHHHHCCCCCCCCHHHHHHCCEEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHH
WVRQLRSQAYVEYRVNRQR
HHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA