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The map label for this gene is yedX [C]

Identifier: 73539738

GI number: 73539738

Start: 43952

End: 44458

Strand: Reverse

Name: yedX [C]

Synonym: Reut_A0032

Alternate gene names: 73539738

Gene position: 44458-43952 (Counterclockwise)

Preceding gene: 73539739

Following gene: 73539737

Centisome position: 1.17

GC content: 67.46

Gene sequence:

>507_bases
ATGCGCAACGACCAAGATCCGGATTTCGACGCCAGCCGCCGCCGCTTCGCATTGCAATCGCTCACGCTGGGTGGTGGCGC
CCTGCTCGCCGGCAGCGCGCTGGCAGAGACCGCGCCCAACCAGACCACAGGCCCTGTGCAGCAAGGCGGCCTGAGCCCGC
GCCTGACCATGCATGCGCTCGACACCTGGCACGGCACCCCTGCCGCCGGCATGCGGGTGGATATGCATCGCATCGAGAAC
GGCCAGCCACGCCACATGCAGACCGTCACGCTCGCTGCCAATGGCCGCAGCGAACCGCCGCTGCTGATTGGCGACGCCTA
TCGCACCGGCACCTACGAATTGCTGCTGCACGTCGATGAGTACTTCGCCGCGCGCAAGGCCAATCTGCCGCAGCCGCTGT
TCCTGTCGAAGATCCCGCTGCGGTTCCGCGTGACCGACGCCAGCCAGCGCATCCACCTGCCCGTGCTGTTCGGGCCGTGG
AGCTACAACTACTACCGCGGCAGCTGA

Upstream 100 bases:

>100_bases
GTCAACACCGGCCTGTACCTGGTGGCCGTCATCGAAATCCTGGCTGCGGTGCTGGTCGTGGTCGGCATCCGCCAACTCCG
CAACAAGCGCGAGGCCTGAT

Downstream 100 bases:

>100_bases
TGCCGCCGGCTTGCTGACAAGGAGACCGATCATGGCAGGCATCAGCACCCACGTACTCGACGTATCGCTCGGCAAGCCCG
TTTCGGGCATGCAGATCGAA

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 168; Mature: 168

Protein sequence:

>168_residues
MRNDQDPDFDASRRRFALQSLTLGGGALLAGSALAETAPNQTTGPVQQGGLSPRLTMHALDTWHGTPAAGMRVDMHRIEN
GQPRHMQTVTLAANGRSEPPLLIGDAYRTGTYELLLHVDEYFAARKANLPQPLFLSKIPLRFRVTDASQRIHLPVLFGPW
SYNYYRGS

Sequences:

>Translated_168_residues
MRNDQDPDFDASRRRFALQSLTLGGGALLAGSALAETAPNQTTGPVQQGGLSPRLTMHALDTWHGTPAAGMRVDMHRIEN
GQPRHMQTVTLAANGRSEPPLLIGDAYRTGTYELLLHVDEYFAARKANLPQPLFLSKIPLRFRVTDASQRIHLPVLFGPW
SYNYYRGS
>Mature_168_residues
MRNDQDPDFDASRRRFALQSLTLGGGALLAGSALAETAPNQTTGPVQQGGLSPRLTMHALDTWHGTPAAGMRVDMHRIEN
GQPRHMQTVTLAANGRSEPPLLIGDAYRTGTYELLLHVDEYFAARKANLPQPLFLSKIPLRFRVTDASQRIHLPVLFGPW
SYNYYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 18597; Mature: 18597

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNDQDPDFDASRRRFALQSLTLGGGALLAGSALAETAPNQTTGPVQQGGLSPRLTMHAL
CCCCCCCCCCCHHHHHHHHHEECCCCCEEECCHHHHCCCCCCCCCHHHCCCCCEEEEEEE
DTWHGTPAAGMRVDMHRIENGQPRHMQTVTLAANGRSEPPLLIGDAYRTGTYELLLHVDE
ECCCCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCEEEEEEEHHH
YFAARKANLPQPLFLSKIPLRFRVTDASQRIHLPVLFGPWSYNYYRGS
HHHHHHCCCCCCEEEECCCEEEEEECCCCEEEEEEEECCCCCCEEECC
>Mature Secondary Structure
MRNDQDPDFDASRRRFALQSLTLGGGALLAGSALAETAPNQTTGPVQQGGLSPRLTMHAL
CCCCCCCCCCCHHHHHHHHHEECCCCCEEECCHHHHCCCCCCCCCHHHCCCCCEEEEEEE
DTWHGTPAAGMRVDMHRIENGQPRHMQTVTLAANGRSEPPLLIGDAYRTGTYELLLHVDE
ECCCCCCCCCEEEEEEECCCCCCCEEEEEEEEECCCCCCCEEEECCCCCCEEEEEEEHHH
YFAARKANLPQPLFLSKIPLRFRVTDASQRIHLPVLFGPWSYNYYRGS
HHHHHHCCCCCCEEEECCCEEEEEECCCCEEEEEEEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]