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The map label for this gene is yedX [C]

Identifier: 73539737

GI number: 73539737

Start: 43585

End: 43920

Strand: Reverse

Name: yedX [C]

Synonym: Reut_A0031

Alternate gene names: 73539737

Gene position: 43920-43585 (Counterclockwise)

Preceding gene: 73539738

Following gene: 73539736

Centisome position: 1.15

GC content: 64.58

Gene sequence:

>336_bases
ATGGCAGGCATCAGCACCCACGTACTCGACGTATCGCTCGGCAAGCCCGTTTCGGGCATGCAGATCGAACTGTTCGACAT
GGGCACGCAACCCCCGAAGCTCATCGCCCGCGCGCGCACCAACAGCGACGGACGCACCGATACGCCGATGTTGCCCGCCA
CGCAGGCGCGCACCGGCGACTTCGAACTGCGCTTCTGGGTCGCGGACTACTTCAAAACACCCGATGTGTTCGCGGACATC
GTGCCCGTGCGCTTCACCATCGCCGATGCGGCACAGCACTACCATGTGCCGCTGCTGTGCTCGCCGTGGAGCTTCGGCAC
GTATCGCGGCAGCTGA

Upstream 100 bases:

>100_bases
GCCAGCCAGCGCATCCACCTGCCCGTGCTGTTCGGGCCGTGGAGCTACAACTACTACCGCGGCAGCTGATGCCGCCGGCT
TGCTGACAAGGAGACCGATC

Downstream 100 bases:

>100_bases
TTCTTTCGTGGTACTTGGGTGCGCATCGTGCGCCCGGGCGGCCCAGCGAGGCCGCCCGTTTTTGTTTGTGGCACCTCATT
CATATCAGCGTCATGGTCAC

Product: transthyretin

Products: NA

Alternate protein names: HIU hydrolase; HIUHase [H]

Number of amino acids: Translated: 111; Mature: 110

Protein sequence:

>111_residues
MAGISTHVLDVSLGKPVSGMQIELFDMGTQPPKLIARARTNSDGRTDTPMLPATQARTGDFELRFWVADYFKTPDVFADI
VPVRFTIADAAQHYHVPLLCSPWSFGTYRGS

Sequences:

>Translated_111_residues
MAGISTHVLDVSLGKPVSGMQIELFDMGTQPPKLIARARTNSDGRTDTPMLPATQARTGDFELRFWVADYFKTPDVFADI
VPVRFTIADAAQHYHVPLLCSPWSFGTYRGS
>Mature_110_residues
AGISTHVLDVSLGKPVSGMQIELFDMGTQPPKLIARARTNSDGRTDTPMLPATQARTGDFELRFWVADYFKTPDVFADIV
PVRFTIADAAQHYHVPLLCSPWSFGTYRGS

Specific function: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) [H]

COG id: COG2351

COG function: function code R; Transthyretin-like protein

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788281, Length=110, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI115532922, Length=112, Percent_Identity=41.0714285714286, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115532920, Length=112, Percent_Identity=41.0714285714286, Blast_Score=76, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534555, Length=112, Percent_Identity=40.1785714285714, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014306
- InterPro:   IPR000895 [H]

Pfam domain/function: PF00576 Transthyretin [H]

EC number: =3.5.2.17 [H]

Molecular weight: Translated: 12274; Mature: 12143

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGISTHVLDVSLGKPVSGMQIELFDMGTQPPKLIARARTNSDGRTDTPMLPATQARTGD
CCCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCCCCCCCCCCCC
FELRFWVADYFKTPDVFADIVPVRFTIADAAQHYHVPLLCSPWSFGTYRGS
EEEEEEEECCCCCCCHHHCEEEEEEEEECCCCCCCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
AGISTHVLDVSLGKPVSGMQIELFDMGTQPPKLIARARTNSDGRTDTPMLPATQARTGD
CCCCCEEEEEECCCCCCCCEEEEEECCCCCHHHEEEECCCCCCCCCCCCCCCCCCCCCC
FELRFWVADYFKTPDVFADIVPVRFTIADAAQHYHVPLLCSPWSFGTYRGS
EEEEEEEECCCCCCCHHHCEEEEEEEEECCCCCCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11756688 [H]