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The map label for this gene is ttuB [H]

Identifier: 73539739

GI number: 73539739

Start: 44460

End: 45800

Strand: Reverse

Name: ttuB [H]

Synonym: Reut_A0033

Alternate gene names: 73539739

Gene position: 45800-44460 (Counterclockwise)

Preceding gene: 73539742

Following gene: 73539738

Centisome position: 1.2

GC content: 65.18

Gene sequence:

>1341_bases
ATGTCTATCACGAAACAAGGCGTGCCGATCTTCGCCGGCGCGGCGGACGACGCGGAAGCGAGCGTCTACCGCAAGGTGTC
CTGGCGCCTGCTGCCCTTCCTGGGCGTGCTGTGGGTGCTGGCCTGGCTGGACCGCGTGAACATTGGCTTTGCCAAGCTGC
AGATGCTCGATGCGCTGCAGTTCAGCGAGGCGGTGTACGGGCTCGGCGCCGGCATCTTCTTCATCGGCTACTTCCTGTTC
GAAGTGCCGTCGAACGTGCTGCTGCAGAAGATCGGCGCGAAGAAGACCATCATGCGCATCACCATCTGCTGGGGCGTGAT
CTGCATGCTGCAGACCTTCGTCACCACCCCCACGCAGTTCTACATCCTGCGCTTCCTGCTCGGCGCGTTCGAAGCGGGCT
TTTATCCGGGCGTGATCCTGTACCTGACGTACTGGTACCCGTCAGAGCGGCGCGCCCGGGCGTTCGGCACGTTCATGTCG
GCGTCCGCCATCGCCGGCGTGCTCGGCGGCCCGCTGGCCGGCTGGATCATGACGTCGATGAGCGGCGTGCATGGCATGCA
CGGCTGGCAGTGGCTGTTCGTCATCGAAGGCGTGCCGTCCGTGCTGGCCGGCGTGTTCGCATGGTTCTACATGACCGACA
AGCCGGAGCAAGCGCAATGGCTGACCGACGGCGAGAAGCGCGTGGTGCACGACGCGCTCAAGCGCGACAACGCCGCCATG
GGCGAGCGCGGCCACGACTGGCGCAGCGTCTTCACCAACCCCAAGGTGTGGCTGCTGATCGCGATCTACTTCTGCCTGCT
GTGCGCGAATTCCACGCTGACGTTCTGGATCCCGACCATCATCAAGGACGTCGGCTTCACCACGCCGATGGCCGTTGGCT
GGATCGCAGCAGTGGCCTACCTGTGCGGCGCTATCGGCATGATCGCCAACGGTGCGCACTCGGACCGCCGCAATGAAGTG
CGCTGGCATTTCAGCGGCGCGGCGCTGACCGGCGGCGTAACGATGGCCTTGCTTGCCGTGCTGCTTGGCATGAATGCGCT
GTCGCCCGTGATCGCCCTGCTCGCCATGACCGCTGCACTGGTCGGCACCATGAGCGCGATCCCCGTGTTCTGGCAGTTGC
CCAACCGGTACCTGGCGGGCAGCGCCGCGGCGGTAGGCGTGGCGCTCATCAACTCGGTCTCCAACCTCGCCGGCTTCGGT
GCGCCGTACGTGATGGGGCTGATCAAGACATCGACCGGCAAGGTCAACACCGGCCTGTACCTGGTGGCCGTCATCGAAAT
CCTGGCTGCGGTGCTGGTCGTGGTCGGCATCCGCCAACTCCGCAACAAGCGCGAGGCCTGA

Upstream 100 bases:

>100_bases
TGGCCGTTCCTATACTTGCTTCCAACCAAACGGACGGCGGCCGCCGGACCACCTTCGGGGCCCCGGCCGCACGATGCAAA
CCGACAAGACAGGAGACACC

Downstream 100 bases:

>100_bases
TATGCGCAACGACCAAGATCCGGATTTCGACGCCAGCCGCCGCCGCTTCGCATTGCAATCGCTCACGCTGGGTGGTGGCG
CCCTGCTCGCCGGCAGCGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSITKQGVPIFAGAADDAEASVYRKVSWRLLPFLGVLWVLAWLDRVNIGFAKLQMLDALQFSEAVYGLGAGIFFIGYFLF
EVPSNVLLQKIGAKKTIMRITICWGVICMLQTFVTTPTQFYILRFLLGAFEAGFYPGVILYLTYWYPSERRARAFGTFMS
ASAIAGVLGGPLAGWIMTSMSGVHGMHGWQWLFVIEGVPSVLAGVFAWFYMTDKPEQAQWLTDGEKRVVHDALKRDNAAM
GERGHDWRSVFTNPKVWLLIAIYFCLLCANSTLTFWIPTIIKDVGFTTPMAVGWIAAVAYLCGAIGMIANGAHSDRRNEV
RWHFSGAALTGGVTMALLAVLLGMNALSPVIALLAMTAALVGTMSAIPVFWQLPNRYLAGSAAAVGVALINSVSNLAGFG
APYVMGLIKTSTGKVNTGLYLVAVIEILAAVLVVVGIRQLRNKREA

Sequences:

>Translated_446_residues
MSITKQGVPIFAGAADDAEASVYRKVSWRLLPFLGVLWVLAWLDRVNIGFAKLQMLDALQFSEAVYGLGAGIFFIGYFLF
EVPSNVLLQKIGAKKTIMRITICWGVICMLQTFVTTPTQFYILRFLLGAFEAGFYPGVILYLTYWYPSERRARAFGTFMS
ASAIAGVLGGPLAGWIMTSMSGVHGMHGWQWLFVIEGVPSVLAGVFAWFYMTDKPEQAQWLTDGEKRVVHDALKRDNAAM
GERGHDWRSVFTNPKVWLLIAIYFCLLCANSTLTFWIPTIIKDVGFTTPMAVGWIAAVAYLCGAIGMIANGAHSDRRNEV
RWHFSGAALTGGVTMALLAVLLGMNALSPVIALLAMTAALVGTMSAIPVFWQLPNRYLAGSAAAVGVALINSVSNLAGFG
APYVMGLIKTSTGKVNTGLYLVAVIEILAAVLVVVGIRQLRNKREA
>Mature_445_residues
SITKQGVPIFAGAADDAEASVYRKVSWRLLPFLGVLWVLAWLDRVNIGFAKLQMLDALQFSEAVYGLGAGIFFIGYFLFE
VPSNVLLQKIGAKKTIMRITICWGVICMLQTFVTTPTQFYILRFLLGAFEAGFYPGVILYLTYWYPSERRARAFGTFMSA
SAIAGVLGGPLAGWIMTSMSGVHGMHGWQWLFVIEGVPSVLAGVFAWFYMTDKPEQAQWLTDGEKRVVHDALKRDNAAMG
ERGHDWRSVFTNPKVWLLIAIYFCLLCANSTLTFWIPTIIKDVGFTTPMAVGWIAAVAYLCGAIGMIANGAHSDRRNEVR
WHFSGAALTGGVTMALLAVLLGMNALSPVIALLAMTAALVGTMSAIPVFWQLPNRYLAGSAAAVGVALINSVSNLAGFGA
PYVMGLIKTSTGKVNTGLYLVAVIEILAAVLVVVGIRQLRNKREA

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=479, Percent_Identity=20.8768267223382, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082071, Length=424, Percent_Identity=36.0849056603774, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI87082320, Length=419, Percent_Identity=24.582338902148, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789515, Length=455, Percent_Identity=22.8571428571429, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789152, Length=457, Percent_Identity=21.6630196936543, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI2367379, Length=424, Percent_Identity=22.877358490566, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI2367193, Length=291, Percent_Identity=23.0240549828179, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569727, Length=168, Percent_Identity=24.4047619047619, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=238, Percent_Identity=30.672268907563, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321698, Length=342, Percent_Identity=27.1929824561404, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6319250, Length=241, Percent_Identity=24.4813278008299, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6324410, Length=151, Percent_Identity=29.8013245033113, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=385, Percent_Identity=22.0779220779221, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6321502, Length=246, Percent_Identity=24.390243902439, Blast_Score=73, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6323032, Length=238, Percent_Identity=26.0504201680672, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322612, Length=229, Percent_Identity=22.707423580786, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641682, Length=382, Percent_Identity=24.869109947644, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48547; Mature: 48416

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITKQGVPIFAGAADDAEASVYRKVSWRLLPFLGVLWVLAWLDRVNIGFAKLQMLDALQ
CCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FSEAVYGLGAGIFFIGYFLFEVPSNVLLQKIGAKKTIMRITICWGVICMLQTFVTTPTQF
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
YILRFLLGAFEAGFYPGVILYLTYWYPSERRARAFGTFMSASAIAGVLGGPLAGWIMTSM
HHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SGVHGMHGWQWLFVIEGVPSVLAGVFAWFYMTDKPEQAQWLTDGEKRVVHDALKRDNAAM
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHCCCCCC
GERGHDWRSVFTNPKVWLLIAIYFCLLCANSTLTFWIPTIIKDVGFTTPMAVGWIAAVAY
CCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHH
LCGAIGMIANGAHSDRRNEVRWHFSGAALTGGVTMALLAVLLGMNALSPVIALLAMTAAL
HHHHHHHHHCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VGTMSAIPVFWQLPNRYLAGSAAAVGVALINSVSNLAGFGAPYVMGLIKTSTGKVNTGLY
HHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHH
LVAVIEILAAVLVVVGIRQLRNKREA
HHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SITKQGVPIFAGAADDAEASVYRKVSWRLLPFLGVLWVLAWLDRVNIGFAKLQMLDALQ
CCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
FSEAVYGLGAGIFFIGYFLFEVPSNVLLQKIGAKKTIMRITICWGVICMLQTFVTTPTQF
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHH
YILRFLLGAFEAGFYPGVILYLTYWYPSERRARAFGTFMSASAIAGVLGGPLAGWIMTSM
HHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
SGVHGMHGWQWLFVIEGVPSVLAGVFAWFYMTDKPEQAQWLTDGEKRVVHDALKRDNAAM
CCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHCCCCCC
GERGHDWRSVFTNPKVWLLIAIYFCLLCANSTLTFWIPTIIKDVGFTTPMAVGWIAAVAY
CCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHH
LCGAIGMIANGAHSDRRNEVRWHFSGAALTGGVTMALLAVLLGMNALSPVIALLAMTAAL
HHHHHHHHHCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VGTMSAIPVFWQLPNRYLAGSAAAVGVALINSVSNLAGFGAPYVMGLIKTSTGKVNTGLY
HHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCHH
LVAVIEILAAVLVVVGIRQLRNKREA
HHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]