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The map label for this gene is yfbQ [H]

Identifier: 71908006

GI number: 71908006

Start: 2572908

End: 2574152

Strand: Reverse

Name: yfbQ [H]

Synonym: Daro_2387

Alternate gene names: 71908006

Gene position: 2574152-2572908 (Counterclockwise)

Preceding gene: 71908008

Following gene: 71908005

Centisome position: 57.19

GC content: 55.74

Gene sequence:

>1245_bases
ATGAAACACGTCAAGAAATCCGCCAAACTCGCCAACGTCTGCTACGACATTCGCGGCCCCGTGCTGCAAAAAGCCAAGCA
GATGGAGGAAGAGGGTCACAAGATCATCAAGCTGAACATCGGCAACCTGGCCGCGTTCGGTTTTGATTCGCCCGAGGAAA
TCCAGCAGGACATGATCCGCAACCTGCCGAATGCGGCTGGTTATACGGATTCCAAGGGTATTTTCGCGGCGCGTAAGGCG
ATCATGCATTACACCCAACAGAAGGGCATCAAGGGCGTGACGCTGGAGGATATCTACGTCGGTAACGGCGTGTCCGAACT
GATCGTCATGGCCATGAACGCCTTGCTCGATGCCGGTGACGAAGTGCTGGTCCCGGCGCCGGATTACCCGCTATGGACGG
CAGCGATCAGCCTGTCCGGCGGAACGCCAAAGCATTACCTGTGCGACGAGAGCAAGGGCTGGCTGCCAGATCTCGACGAT
ATCCGCAGCAAGATCAACGCCCACACCAAGGCGATCGTGCTGATCAACCCGAATAATCCGACCGGCGCCCTTTACCCGGA
TGATCTGCTGTACGAGATCATTGACATCGCCCGTCAGCATCACCTGACTATCTACGCCGACGAGGTGTACGACAAGGTGC
TCTACGACGATGTGAAGCACACGTCGATTGCCTCGCTGGCCGAGGATGTGCTGATGATCACGTTCAATGGTCTGTCGAAG
AACTATCGTTCTTGCGGTTATCGTGCCGGCTGGATGGTGGTTTCCGGCGACAAGCGCCATGCCAAGGACTATATCGAAGG
CCTCGACATGCTGGCCTCGATGCGTCTGTGTGCTAACGCACCGGGGCAGCACGGTATCCAGACGGCCTTGGGTGGTTATC
AGAGTATCAATGATCTAATCAAGGACGGCGGTCGCCTACGTCGTCAGCGCGACATCGCCCACGAGCTGATTACAGCCATT
CCTGGCGTCACCTGCGTCAAGCCGAAGGCCGCGTTGTACATGTTCCCAAGGCTTGACCCGAAGATTTACCCGATCAAGAA
CGATCAACAGTTCATTTCCGAGCTGTTGCAGGAAGAGAAAGTGTTACTGGTTCAGGGGACTGGCTTCAACTGGCCGCATC
CCGACCATTTCCGTCTTGTCTTCCTGCCGCACGAGGATGACCTGCGGGAAGCAGTCGCACGTATTGCCCGCTTTCTTGAA
AATTATCGCAAACGTCACAACACCAACCAACTTATCAAAGACTGA

Upstream 100 bases:

>100_bases
TCGTTCCAAAAAGTCCGCGCAAAATTGCGGTGCACCATTCGATAAAGTAGGATTATACCTTTGGCCTTTGTTGGCCAAGC
CGCCACGCCGGAAGATTCGC

Downstream 100 bases:

>100_bases
ACATGAAACCCATCAATGTTGGCCTTATCGGCATCGGCACCGTCGGCGGTGGCACCTGGACCGTTCTTAAGCGCAACGAG
GAAGAGATTACCCGTCGTGC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MKHVKKSAKLANVCYDIRGPVLQKAKQMEEEGHKIIKLNIGNLAAFGFDSPEEIQQDMIRNLPNAAGYTDSKGIFAARKA
IMHYTQQKGIKGVTLEDIYVGNGVSELIVMAMNALLDAGDEVLVPAPDYPLWTAAISLSGGTPKHYLCDESKGWLPDLDD
IRSKINAHTKAIVLINPNNPTGALYPDDLLYEIIDIARQHHLTIYADEVYDKVLYDDVKHTSIASLAEDVLMITFNGLSK
NYRSCGYRAGWMVVSGDKRHAKDYIEGLDMLASMRLCANAPGQHGIQTALGGYQSINDLIKDGGRLRRQRDIAHELITAI
PGVTCVKPKAALYMFPRLDPKIYPIKNDQQFISELLQEEKVLLVQGTGFNWPHPDHFRLVFLPHEDDLREAVARIARFLE
NYRKRHNTNQLIKD

Sequences:

>Translated_414_residues
MKHVKKSAKLANVCYDIRGPVLQKAKQMEEEGHKIIKLNIGNLAAFGFDSPEEIQQDMIRNLPNAAGYTDSKGIFAARKA
IMHYTQQKGIKGVTLEDIYVGNGVSELIVMAMNALLDAGDEVLVPAPDYPLWTAAISLSGGTPKHYLCDESKGWLPDLDD
IRSKINAHTKAIVLINPNNPTGALYPDDLLYEIIDIARQHHLTIYADEVYDKVLYDDVKHTSIASLAEDVLMITFNGLSK
NYRSCGYRAGWMVVSGDKRHAKDYIEGLDMLASMRLCANAPGQHGIQTALGGYQSINDLIKDGGRLRRQRDIAHELITAI
PGVTCVKPKAALYMFPRLDPKIYPIKNDQQFISELLQEEKVLLVQGTGFNWPHPDHFRLVFLPHEDDLREAVARIARFLE
NYRKRHNTNQLIKD
>Mature_414_residues
MKHVKKSAKLANVCYDIRGPVLQKAKQMEEEGHKIIKLNIGNLAAFGFDSPEEIQQDMIRNLPNAAGYTDSKGIFAARKA
IMHYTQQKGIKGVTLEDIYVGNGVSELIVMAMNALLDAGDEVLVPAPDYPLWTAAISLSGGTPKHYLCDESKGWLPDLDD
IRSKINAHTKAIVLINPNNPTGALYPDDLLYEIIDIARQHHLTIYADEVYDKVLYDDVKHTSIASLAEDVLMITFNGLSK
NYRSCGYRAGWMVVSGDKRHAKDYIEGLDMLASMRLCANAPGQHGIQTALGGYQSINDLIKDGGRLRRQRDIAHELITAI
PGVTCVKPKAALYMFPRLDPKIYPIKNDQQFISELLQEEKVLLVQGTGFNWPHPDHFRLVFLPHEDDLREAVARIARFLE
NYRKRHNTNQLIKD

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=464, Percent_Identity=25.8620689655172, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=27.3209549071618, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI215599424, Length=398, Percent_Identity=26.1306532663317, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=24.3303571428571, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI95147551, Length=172, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI169881279, Length=172, Percent_Identity=30.2325581395349, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI56713254, Length=171, Percent_Identity=29.2397660818713, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI56713256, Length=302, Percent_Identity=24.5033112582781, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI169881281, Length=158, Percent_Identity=28.4810126582279, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI187936925, Length=380, Percent_Identity=24.2105263157895, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI14211921, Length=380, Percent_Identity=24.2105263157895, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=65.8415841584158, Blast_Score=576, Evalue=1e-165,
Organism=Escherichia coli, GI1788722, Length=370, Percent_Identity=26.7567567567568, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786816, Length=382, Percent_Identity=24.6073298429319, Blast_Score=85, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=382, Percent_Identity=28.7958115183246, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=462, Percent_Identity=24.025974025974, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71981215, Length=295, Percent_Identity=26.4406779661017, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=179, Percent_Identity=29.0502793296089, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=179, Percent_Identity=29.0502793296089, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567369, Length=212, Percent_Identity=26.4150943396226, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=381, Percent_Identity=27.0341207349081, Blast_Score=141, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6323118, Length=382, Percent_Identity=25.3926701570681, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322401, Length=414, Percent_Identity=24.6376811594203, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI18859735, Length=381, Percent_Identity=28.0839895013123, Blast_Score=162, Evalue=4e-40,
Organism=Drosophila melanogaster, GI45551451, Length=463, Percent_Identity=26.9978401727862, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24641770, Length=463, Percent_Identity=26.9978401727862, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24641760, Length=463, Percent_Identity=26.9978401727862, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24641768, Length=463, Percent_Identity=26.9978401727862, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24641766, Length=463, Percent_Identity=26.9978401727862, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24641764, Length=463, Percent_Identity=26.9978401727862, Blast_Score=138, Evalue=7e-33,
Organism=Drosophila melanogaster, GI28573069, Length=166, Percent_Identity=26.5060240963855, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646114, Length=166, Percent_Identity=26.5060240963855, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573067, Length=166, Percent_Identity=26.5060240963855, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28573065, Length=166, Percent_Identity=26.5060240963855, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 46473; Mature: 46473

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHVKKSAKLANVCYDIRGPVLQKAKQMEEEGHKIIKLNIGNLAAFGFDSPEEIQQDMIR
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHHHHHHHH
NLPNAAGYTDSKGIFAARKAIMHYTQQKGIKGVTLEDIYVGNGVSELIVMAMNALLDAGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EVLVPAPDYPLWTAAISLSGGTPKHYLCDESKGWLPDLDDIRSKINAHTKAIVLINPNNP
CEEECCCCCCEEEEEEEECCCCCCCEECCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCC
TGALYPDDLLYEIIDIARQHHLTIYADEVYDKVLYDDVKHTSIASLAEDVLMITFNGLSK
CCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCC
NYRSCGYRAGWMVVSGDKRHAKDYIEGLDMLASMRLCANAPGQHGIQTALGGYQSINDLI
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHH
KDGGRLRRQRDIAHELITAIPGVTCVKPKAALYMFPRLDPKIYPIKNDQQFISELLQEEK
HCCHHHHHHHHHHHHHHHHCCCCEEECCCHHEEEECCCCCEEEECCCHHHHHHHHHCCCC
VLLVQGTGFNWPHPDHFRLVFLPHEDDLREAVARIARFLENYRKRHNTNQLIKD
EEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MKHVKKSAKLANVCYDIRGPVLQKAKQMEEEGHKIIKLNIGNLAAFGFDSPEEIQQDMIR
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCEEEECCCCHHHHHHHHHH
NLPNAAGYTDSKGIFAARKAIMHYTQQKGIKGVTLEDIYVGNGVSELIVMAMNALLDAGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCC
EVLVPAPDYPLWTAAISLSGGTPKHYLCDESKGWLPDLDDIRSKINAHTKAIVLINPNNP
CEEECCCCCCEEEEEEEECCCCCCCEECCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCC
TGALYPDDLLYEIIDIARQHHLTIYADEVYDKVLYDDVKHTSIASLAEDVLMITFNGLSK
CCCCCCHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCC
NYRSCGYRAGWMVVSGDKRHAKDYIEGLDMLASMRLCANAPGQHGIQTALGGYQSINDLI
HHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHH
KDGGRLRRQRDIAHELITAIPGVTCVKPKAALYMFPRLDPKIYPIKNDQQFISELLQEEK
HCCHHHHHHHHHHHHHHHHCCCCEEECCCHHEEEECCCCCEEEECCCHHHHHHHHHCCCC
VLLVQGTGFNWPHPDHFRLVFLPHEDDLREAVARIARFLENYRKRHNTNQLIKD
EEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]