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The map label for this gene is xanB [H]

Identifier: 71908008

GI number: 71908008

Start: 2574632

End: 2576071

Strand: Reverse

Name: xanB [H]

Synonym: Daro_2389

Alternate gene names: 71908008

Gene position: 2576071-2574632 (Counterclockwise)

Preceding gene: 71908009

Following gene: 71908006

Centisome position: 57.23

GC content: 55.14

Gene sequence:

>1440_bases
ATGACGCAAGTGATACCCGTTGTGCTCTCCGGAGGTTCTGGAACCCGTTTGTGGCCCTTGTCCCGCGAAAAGTATCCCAA
GCAGTTGCTGCCGCTGGTTGGCGACAAATCGATGTTGCAAGAAACCGTGGCGCGGTTGGATGGGCTTGCCGGGTTGTCTG
AGCCTTTGCTGGTCTGTAACGAAGAGCATCGTTTTGTCGTGGCCGAACAGCTTCGGGTGCTGGGTAAGCATGGCCAGATA
CTGCTTGAGCCATTTGGTCGCAATACCGCACCGGCGCTAACGCTGGCAGCCTTGTTGGCGCGACAGAATGGTGATGACCC
TGTTCTGGTGGTCATGCCGGCGGATCATGTGATTCTTGAGGGAGATGTTTTCCGGGAGGCGGTTGCCAACGCGGTAAAAC
TTGCTGAGCAAGGATATGCCGTTACTTTCGGGATTACTCCGGATTGCCCAGAGACTGGCTATGGTTACATCCACCGTGGT
GCCGCTATTGCATGCGAAGAAGAAGCCTTTTTGCTTCGCCGCTTCGTCGAGAAGCCGGATCGTGGTACCGCTCAAGCTTA
TCTGGATTCAGGCGATTACCTGTGGAATAGCGGTATTTTCGTGCTGCGCGTGTCGACTTGGCTGTCTGCGTTGGAGATTT
GCCGGCCTGACATCTTGGCGGCTTGTGGTAAAGCCTTGAACTGCGTCAGTCAGGACGGCGATTTTGTGCGACTCGATCGT
GCCGAGTTTGAGCGTTGTCCATCGGATTCCATTGATTACGCAGTCATGGAGCGCCTTTCCGGTGGGGAGGCAAATTTGCC
AAAAAGTGCGGTTATTCCGCTTTCCGCTGGCTGGTCTGATGTCGGTGCCTGGGATGCACTGTGGAAGGTGTTGCCGAAGT
GTGAGGCGGGAAATGCCATCCGCGGTGATGTCATGCTCGAATCCTGCAGCAACACTCTGGCGTTTTCCGAGAGTCGTCTG
GTGACCTGTATTGGTCTCAAGGATCTGGTTGTGGTTGAGACTAACGATGCTGTCCTGGTCGCTCACCAAAATGCGACGCA
GGACGTCAAAAAGATTGTTGATCGTCTGAAGGCCGACAAGCGTTCAGTGGCGCAGTGGCATCGCAAGATTCATCGGCCGT
GGGGGTGGTATGACGGAGTTGATTCTGGGCAGCGTTTTCAGGTGAAACGGATCTGTGTGAAGCCGGGGGCTTCGTTATCC
CTGCAGATGCACCATCATCGTGCCGAGCACTGGATCGTTGTTACCGGTACAGCGAAAGTAACCAAGGGCGACGAGGCGTT
TCTGGTTTCCGAGAACCAGTCGACCTATATCCCGCTCGGTACCAAGCATCGCCTGGAAAATCCGGGGATCGTGCCGCTCG
AAATGATCGAGGTGCAGTCTGGAAGCTATCTTGGCGAGGACGATATTGTCCGCTTTGAAGATACCTACGGGCGCAACTGA

Upstream 100 bases:

>100_bases
TACGTGATTTGCCGGACAAGATTTTTACCAAGGAGTATCTGAAGAAACTGGATTAGTATGCTTTTTGGTTATTCTTCTAT
TTGGTTGAAAGTTTTTGAAA

Downstream 100 bases:

>100_bases
TCAGTCGAAGATGAGGGCTGCAGCCACTTTGCGGCCCTCGGCAGCAAGGATGTTGTAAGTGCGACAGGCGGCTTGCAGGT
CCATGACATCCAGCCCAATG

Product: mannose-1-phosphate guanylyltransferase (GDP)

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 479; Mature: 478

Protein sequence:

>479_residues
MTQVIPVVLSGGSGTRLWPLSREKYPKQLLPLVGDKSMLQETVARLDGLAGLSEPLLVCNEEHRFVVAEQLRVLGKHGQI
LLEPFGRNTAPALTLAALLARQNGDDPVLVVMPADHVILEGDVFREAVANAVKLAEQGYAVTFGITPDCPETGYGYIHRG
AAIACEEEAFLLRRFVEKPDRGTAQAYLDSGDYLWNSGIFVLRVSTWLSALEICRPDILAACGKALNCVSQDGDFVRLDR
AEFERCPSDSIDYAVMERLSGGEANLPKSAVIPLSAGWSDVGAWDALWKVLPKCEAGNAIRGDVMLESCSNTLAFSESRL
VTCIGLKDLVVVETNDAVLVAHQNATQDVKKIVDRLKADKRSVAQWHRKIHRPWGWYDGVDSGQRFQVKRICVKPGASLS
LQMHHHRAEHWIVVTGTAKVTKGDEAFLVSENQSTYIPLGTKHRLENPGIVPLEMIEVQSGSYLGEDDIVRFEDTYGRN

Sequences:

>Translated_479_residues
MTQVIPVVLSGGSGTRLWPLSREKYPKQLLPLVGDKSMLQETVARLDGLAGLSEPLLVCNEEHRFVVAEQLRVLGKHGQI
LLEPFGRNTAPALTLAALLARQNGDDPVLVVMPADHVILEGDVFREAVANAVKLAEQGYAVTFGITPDCPETGYGYIHRG
AAIACEEEAFLLRRFVEKPDRGTAQAYLDSGDYLWNSGIFVLRVSTWLSALEICRPDILAACGKALNCVSQDGDFVRLDR
AEFERCPSDSIDYAVMERLSGGEANLPKSAVIPLSAGWSDVGAWDALWKVLPKCEAGNAIRGDVMLESCSNTLAFSESRL
VTCIGLKDLVVVETNDAVLVAHQNATQDVKKIVDRLKADKRSVAQWHRKIHRPWGWYDGVDSGQRFQVKRICVKPGASLS
LQMHHHRAEHWIVVTGTAKVTKGDEAFLVSENQSTYIPLGTKHRLENPGIVPLEMIEVQSGSYLGEDDIVRFEDTYGRN
>Mature_478_residues
TQVIPVVLSGGSGTRLWPLSREKYPKQLLPLVGDKSMLQETVARLDGLAGLSEPLLVCNEEHRFVVAEQLRVLGKHGQIL
LEPFGRNTAPALTLAALLARQNGDDPVLVVMPADHVILEGDVFREAVANAVKLAEQGYAVTFGITPDCPETGYGYIHRGA
AIACEEEAFLLRRFVEKPDRGTAQAYLDSGDYLWNSGIFVLRVSTWLSALEICRPDILAACGKALNCVSQDGDFVRLDRA
EFERCPSDSIDYAVMERLSGGEANLPKSAVIPLSAGWSDVGAWDALWKVLPKCEAGNAIRGDVMLESCSNTLAFSESRLV
TCIGLKDLVVVETNDAVLVAHQNATQDVKKIVDRLKADKRSVAQWHRKIHRPWGWYDGVDSGQRFQVKRICVKPGASLSL
QMHHHRAEHWIVVTGTAKVTKGDEAFLVSENQSTYIPLGTKHRLENPGIVPLEMIEVQSGSYLGEDDIVRFEDTYGRN

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=482, Percent_Identity=55.8091286307054, Blast_Score=530, Evalue=1e-151,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 52724; Mature: 52593

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQVIPVVLSGGSGTRLWPLSREKYPKQLLPLVGDKSMLQETVARLDGLAGLSEPLLVCN
CCCEEEEEEECCCCCEEECCCHHHCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEC
EEHRFVVAEQLRVLGKHGQILLEPFGRNTAPALTLAALLARQNGDDPVLVVMPADHVILE
CCCCEEHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEC
GDVFREAVANAVKLAEQGYAVTFGITPDCPETGYGYIHRGAAIACEEEAFLLRRFVEKPD
CHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEECCEEEEECHHHHHHHHHHCCCC
RGTAQAYLDSGDYLWNSGIFVLRVSTWLSALEICRPDILAACGKALNCVSQDGDFVRLDR
CCCCEEEECCCCEEECCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEH
AEFERCPSDSIDYAVMERLSGGEANLPKSAVIPLSAGWSDVGAWDALWKVLPKCEAGNAI
HHHHHCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEE
RGDVMLESCSNTLAFSESRLVTCIGLKDLVVVETNDAVLVAHQNATQDVKKIVDRLKADK
ECHHHHHHHCCCCEECCCCEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCH
RSVAQWHRKIHRPWGWYDGVDSGQRFQVKRICVKPGASLSLQMHHHRAEHWIVVTGTAKV
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCEEEEEECCEEE
TKGDEAFLVSENQSTYIPLGTKHRLENPGIVPLEMIEVQSGSYLGEDDIVRFEDTYGRN
ECCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
TQVIPVVLSGGSGTRLWPLSREKYPKQLLPLVGDKSMLQETVARLDGLAGLSEPLLVCN
CCEEEEEEECCCCCEEECCCHHHCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEEC
EEHRFVVAEQLRVLGKHGQILLEPFGRNTAPALTLAALLARQNGDDPVLVVMPADHVILE
CCCCEEHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCEEEC
GDVFREAVANAVKLAEQGYAVTFGITPDCPETGYGYIHRGAAIACEEEAFLLRRFVEKPD
CHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEECCEEEEECHHHHHHHHHHCCCC
RGTAQAYLDSGDYLWNSGIFVLRVSTWLSALEICRPDILAACGKALNCVSQDGDFVRLDR
CCCCEEEECCCCEEECCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEEH
AEFERCPSDSIDYAVMERLSGGEANLPKSAVIPLSAGWSDVGAWDALWKVLPKCEAGNAI
HHHHHCCCCCCCHHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCCCCCEE
RGDVMLESCSNTLAFSESRLVTCIGLKDLVVVETNDAVLVAHQNATQDVKKIVDRLKADK
ECHHHHHHHCCCCEECCCCEEEEECCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHCCH
RSVAQWHRKIHRPWGWYDGVDSGQRFQVKRICVKPGASLSLQMHHHRAEHWIVVTGTAKV
HHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCCEEEEEECCEEE
TKGDEAFLVSENQSTYIPLGTKHRLENPGIVPLEMIEVQSGSYLGEDDIVRFEDTYGRN
ECCCCEEEEECCCCEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]