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The map label for this gene is infA2

Identifier: 71906149

GI number: 71906149

Start: 570055

End: 570318

Strand: Reverse

Name: infA2

Synonym: Daro_0509

Alternate gene names: 71906149

Gene position: 570318-570055 (Counterclockwise)

Preceding gene: 71906150

Following gene: 71906143

Centisome position: 12.67

GC content: 58.33

Gene sequence:

>264_bases
TTGGCTAAAGAAGAACTACTTGAAATGCAAGGCGTCGTGAACGACGTCCTCCCCGACACCCGCTTCCGCGTCACGCTGGA
AAACGGCCACGAACTGATCGCCTACACCTCAGGCAAGATGAAGAAGAACCACATCCGCATCCTGGTCGGTGACAAGGTCA
CGCTCGAGCTCTCGCCCTACGATCTGTCCAAGGGCCGCATCACCTTCCGTCACATCGAGAATCGCGGCACACCGAATCCG
CAAGCGCAGCGCCGCCGCTACTAA

Upstream 100 bases:

>100_bases
CCCGTGGGAATTACCCCGCCACCGGCCGGAGGCGATTTCGACCGATGCTTCACCGGTCGACGCCGGCTAAACCCCATTTT
TCAATTACTGGAGAAAACAC

Downstream 100 bases:

>100_bases
TCTTTAGCGCGCCGTCCCGGACGAAACTGCCAGGTATCGTCGTAGTAGTCCGGGTTCTCGCTTTCTGGCGTCACGCCGGG
GATCCCCAGCAGGGGAAGAG

Product: translation initiation factor 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 87; Mature: 86

Protein sequence:

>87_residues
MAKEELLEMQGVVNDVLPDTRFRVTLENGHELIAYTSGKMKKNHIRILVGDKVTLELSPYDLSKGRITFRHIENRGTPNP
QAQRRRY

Sequences:

>Translated_87_residues
MAKEELLEMQGVVNDVLPDTRFRVTLENGHELIAYTSGKMKKNHIRILVGDKVTLELSPYDLSKGRITFRHIENRGTPNP
QAQRRRY
>Mature_86_residues
AKEELLEMQGVVNDVLPDTRFRVTLENGHELIAYTSGKMKKNHIRILVGDKVTLELSPYDLSKGRITFRHIENRGTPNPQ
AQRRRY

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=70, Blast_Score=103, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF12_DECAR (Q47IR5)

Other databases:

- EMBL:   CP000089
- RefSeq:   YP_283736.1
- ProteinModelPortal:   Q47IR5
- SMR:   Q47IR5
- STRING:   Q47IR5
- GeneID:   3569983
- GenomeReviews:   CP000089_GR
- KEGG:   dar:Daro_0509
- NMPDR:   fig|159087.4.peg.93
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   VQLDAGH
- BioCyc:   DARO159087:DARO_0509-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 10092; Mature: 9961

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEELLEMQGVVNDVLPDTRFRVTLENGHELIAYTSGKMKKNHIRILVGDKVTLELSPY
CCHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCEEEEEECCC
DLSKGRITFRHIENRGTPNPQAQRRRY
CCCCCCEEEEEECCCCCCCCCHHCCCC
>Mature Secondary Structure 
AKEELLEMQGVVNDVLPDTRFRVTLENGHELIAYTSGKMKKNHIRILVGDKVTLELSPY
CHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCEEEEEECCC
DLSKGRITFRHIENRGTPNPQAQRRRY
CCCCCCEEEEEECCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA