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The map label for this gene is trpS [H]

Identifier: 71893939

GI number: 71893939

Start: 763761

End: 764747

Strand: Reverse

Name: trpS [H]

Synonym: MHJ_0590

Alternate gene names: 71893939

Gene position: 764747-763761 (Counterclockwise)

Preceding gene: 71893962

Following gene: 71893938

Centisome position: 85.22

GC content: 31.0

Gene sequence:

>987_bases
ATTATGAAAAAAAGATTGGTTACTGGCATTACGGCAACAGGAAAATTAACGCTTGGGAATTATTTAGGATCGATAAAACC
TAGTCTTGATCTGCAAAATGAATACGAAAATTTTATTTTCGTTGCTGACCTTCACGCGCTTACTTTGCCAATTGATCCAA
AAGAATTAGCTGAAAACCGTAAAAGTATTTTTGCTTTTTATCTTGCATGCGGATTTGATCCAGAAAAAACAGTGCTTTTT
TTTCAATCTGAAATTAGCCAACATTCTGAATTATTTTGACTTTTACAGTCTGAAACTACAATTGGTGAACTTTCGAGAAT
GACCCAATTCAAAGACAAAGCGCGTTTAAAACAGGATAATAATACTGAAAAAATTCCCACCGGACTTTTAACTTATCCAA
TTTTGATGGCTGCAGATATTCTTTTGTATAACCCAGATTTTGTAACAGTTGGTGCTGATCAGTTGCAACATCTTGAATTA
GTGCGGAAAATTGCCCAAAGATTTAATAAAATTTATAAAACCGACTTTAAAATTCCAAGAACAATAATTTCTGAAAGAAC
ACAGAAAATTATGTCGCTAACTGATCCAGAAAAAAAGATGTCCAAATCTACTCAATCAAAAAATTCGACTATTTTTTTAA
CAGACAGTCCTGATGAGGCATATCAAAAAATTCAAAAAGCACAAACAGATTCTTATAATGAAGTTAATTTTAATTTTGCA
AAACCTGGAGTTGCCAATCTTTTAAACATTTTTATGGGACTTACTGGAATACCAGTTGATGAAACTCAGGCGTTTTTTGA
GGGAAAATCTTACCAGTTTTTAAAACAAAAAGTTGGGATAATAGTTGCTGAATTTTTAAGAGATTTACAAGAAAAATATC
AAAAAAATCTCGATTTAGTCGAGATTTATGCAAAAAAAGGCGCTAAAAAAGCAAAAGAAGTTGCTGTTTCTAACTTTGAA
AAAATCAAAGAAAAAATAGGATTATAA

Upstream 100 bases:

>100_bases
GTAGAAAAAAATAAATGATTTTAGAAACTAATTTCATAATTATGTTTTAAATTATACTTATTTTTAAAACTTTTTATATA
AATTATGTTAAAATTTTTTA

Downstream 100 bases:

>100_bases
TTTATGGACTTAAAAATTGACTATAAATTAAATCATTCAAGTTCACACCTCTTAGCATTAGCAATTAAAATTCTTTATCC
GGGTGTAAAATTTGGAATTG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MMKKRLVTGITATGKLTLGNYLGSIKPSLDLQNEYENFIFVADLHALTLPIDPKELAENRKSIFAFYLACGFDPEKTVLF
FQSEISQHSELFWLLQSETTIGELSRMTQFKDKARLKQDNNTEKIPTGLLTYPILMAADILLYNPDFVTVGADQLQHLEL
VRKIAQRFNKIYKTDFKIPRTIISERTQKIMSLTDPEKKMSKSTQSKNSTIFLTDSPDEAYQKIQKAQTDSYNEVNFNFA
KPGVANLLNIFMGLTGIPVDETQAFFEGKSYQFLKQKVGIIVAEFLRDLQEKYQKNLDLVEIYAKKGAKKAKEVAVSNFE
KIKEKIGL

Sequences:

>Translated_328_residues
MMKKRLVTGITATGKLTLGNYLGSIKPSLDLQNEYENFIFVADLHALTLPIDPKELAENRKSIFAFYLACGFDPEKTVLF
FQSEISQHSELF*LLQSETTIGELSRMTQFKDKARLKQDNNTEKIPTGLLTYPILMAADILLYNPDFVTVGADQLQHLEL
VRKIAQRFNKIYKTDFKIPRTIISERTQKIMSLTDPEKKMSKSTQSKNSTIFLTDSPDEAYQKIQKAQTDSYNEVNFNFA
KPGVANLLNIFMGLTGIPVDETQAFFEGKSYQFLKQKVGIIVAEFLRDLQEKYQKNLDLVEIYAKKGAKKAKEVAVSNFE
KIKEKIGL
>Mature_328_residues
MMKKRLVTGITATGKLTLGNYLGSIKPSLDLQNEYENFIFVADLHALTLPIDPKELAENRKSIFAFYLACGFDPEKTVLF
FQSEISQHSELF*LLQSETTIGELSRMTQFKDKARLKQDNNTEKIPTGLLTYPILMAADILLYNPDFVTVGADQLQHLEL
VRKIAQRFNKIYKTDFKIPRTIISERTQKIMSLTDPEKKMSKSTQSKNSTIFLTDSPDEAYQKIQKAQTDSYNEVNFNFA
KPGVANLLNIFMGLTGIPVDETQAFFEGKSYQFLKQKVGIIVAEFLRDLQEKYQKNLDLVEIYAKKGAKKAKEVAVSNFE
KIKEKIGL

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=330, Percent_Identity=39.6969696969697, Blast_Score=228, Evalue=4e-60,
Organism=Homo sapiens, GI41352700, Length=183, Percent_Identity=44.8087431693989, Blast_Score=163, Evalue=2e-40,
Organism=Escherichia coli, GI1789786, Length=334, Percent_Identity=41.3173652694611, Blast_Score=249, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71982800, Length=330, Percent_Identity=37.8787878787879, Blast_Score=194, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71982793, Length=330, Percent_Identity=37.8787878787879, Blast_Score=194, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6320474, Length=340, Percent_Identity=39.1176470588235, Blast_Score=207, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24666151, Length=339, Percent_Identity=38.0530973451327, Blast_Score=224, Evalue=5e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37222; Mature: 37222

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKRLVTGITATGKLTLGNYLGSIKPSLDLQNEYENFIFVADLHALTLPIDPKELAENR
CCCHHHHHCCCCCCCEEHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHH
KSIFAFYLACGFDPEKTVLFFQSEISQHSELFLLQSETTIGELSRMTQFKDKARLKQDNN
HHHHHHHHHHCCCCCCEEEEEHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
TEKIPTGLLTYPILMAADILLYNPDFVTVGADQLQHLELVRKIAQRFNKIYKTDFKIPRT
CCCCCCHHHHHHHHHHHHHHEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IISERTQKIMSLTDPEKKMSKSTQSKNSTIFLTDSPDEAYQKIQKAQTDSYNEVNFNFAK
HHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEECC
PGVANLLNIFMGLTGIPVDETQAFFEGKSYQFLKQKVGIIVAEFLRDLQEKYQKNLDLVE
CCHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IYAKKGAKKAKEVAVSNFEKIKEKIGL
HHHHHCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKKRLVTGITATGKLTLGNYLGSIKPSLDLQNEYENFIFVADLHALTLPIDPKELAENR
CCCHHHHHCCCCCCCEEHHHHHCCCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHH
KSIFAFYLACGFDPEKTVLFFQSEISQHSELFLLQSETTIGELSRMTQFKDKARLKQDNN
HHHHHHHHHHCCCCCCEEEEEHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCC
TEKIPTGLLTYPILMAADILLYNPDFVTVGADQLQHLELVRKIAQRFNKIYKTDFKIPRT
CCCCCCHHHHHHHHHHHHHHEECCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IISERTQKIMSLTDPEKKMSKSTQSKNSTIFLTDSPDEAYQKIQKAQTDSYNEVNFNFAK
HHHHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCEECC
PGVANLLNIFMGLTGIPVDETQAFFEGKSYQFLKQKVGIIVAEFLRDLQEKYQKNLDLVE
CCHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
IYAKKGAKKAKEVAVSNFEKIKEKIGL
HHHHHCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11353084 [H]