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The map label for this gene is aroE

Identifier: 71892004

GI number: 71892004

Start: 259379

End: 260254

Strand: Direct

Name: aroE

Synonym: BPEN_228

Alternate gene names: 71892004

Gene position: 259379-260254 (Clockwise)

Preceding gene: 71892003

Following gene: 71892007

Centisome position: 32.76

GC content: 29.79

Gene sequence:

>876_bases
ATGAATTCTTTTGCTGTTTTTGGTAATCCGATTAGACATAGCAAATCAGCAGAGATTTACGCATTATTTGCACATGAAAT
TGGAATATCAAAAGAATACAACCTTAAATTGGCAGTACAAGATAATTTCAATTATTTATTACATAATTTTTTTAAGTTAG
GTGGATTAGGAGCAAATATTACTTCTCCATTTAAAGAAAATGCATATTTTTTGTGTAATCAATTAACTGAACGAGCTGAA
AAAGCTCGTTCAGTTAATACGATAAAAAAATTAAAAAATGGTACTTTGCTGGGAGATAATACAGATGGTATAGGATTTAT
TAGCGATTTAAAACGGCTTAATTGGTTAGATAATAATAATCAAATCATTTCTAACGACGCACCTATACCCATGGTAACGA
ACATTCTGTTAATTGGCGCTGGGGGCGCTGCAAAAGGAATTGTTCCTATATTATTAACGACTATAACAACATGTCACATA
AATATAGTAAATAGAACGTTTTCTAGGGCACAGGAACTGACATCTTATTATCAGGAAATAGGATATAAAAATATATCATG
CTTACCTTTATACAAATTACGTTATGACACCAATAAATATAGTTTAATTATTAATGCTACAACCAGCAATATACATAATA
CTATTCCAAAAATACCATATTTTCTTATTACTCCTGACACTAAATGTTATGATTTATTTTATACAAAACAAGACACGTTG
TTCATAACATGGTGTAAAAAAAACGGGGCAAATTATTGTGCAGACGGATTAGGTATGTTAGTAGGACAAGCGGCTCATTC
ATTTTTATTATGGCATAATACATTTCCTACTATTAATCCTGTGATAGATCATTTAAGATCTGCATTTTATATGTAA

Upstream 100 bases:

>100_bases
TGAAGATATACTTGGGAGACCCAATCCTTCAAAAATTAGAGATGTTATGACTGGTAAACTAATTCGTGAATAATTTTTTA
TTATTCAAGGAGATAAATAG

Downstream 100 bases:

>100_bases
AATTGTATTGATTTGATAACGAAATAAATATAGGGTATAATTCTTTCATAAAATATTTGCTATTATTAAAAAGTATATTG
CGCAATTGAAGTCTATAATT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNSFAVFGNPIRHSKSAEIYALFAHEIGISKEYNLKLAVQDNFNYLLHNFFKLGGLGANITSPFKENAYFLCNQLTERAE
KARSVNTIKKLKNGTLLGDNTDGIGFISDLKRLNWLDNNNQIISNDAPIPMVTNILLIGAGGAAKGIVPILLTTITTCHI
NIVNRTFSRAQELTSYYQEIGYKNISCLPLYKLRYDTNKYSLIINATTSNIHNTIPKIPYFLITPDTKCYDLFYTKQDTL
FITWCKKNGANYCADGLGMLVGQAAHSFLLWHNTFPTINPVIDHLRSAFYM

Sequences:

>Translated_291_residues
MNSFAVFGNPIRHSKSAEIYALFAHEIGISKEYNLKLAVQDNFNYLLHNFFKLGGLGANITSPFKENAYFLCNQLTERAE
KARSVNTIKKLKNGTLLGDNTDGIGFISDLKRLNWLDNNNQIISNDAPIPMVTNILLIGAGGAAKGIVPILLTTITTCHI
NIVNRTFSRAQELTSYYQEIGYKNISCLPLYKLRYDTNKYSLIINATTSNIHNTIPKIPYFLITPDTKCYDLFYTKQDTL
FITWCKKNGANYCADGLGMLVGQAAHSFLLWHNTFPTINPVIDHLRSAFYM
>Mature_291_residues
MNSFAVFGNPIRHSKSAEIYALFAHEIGISKEYNLKLAVQDNFNYLLHNFFKLGGLGANITSPFKENAYFLCNQLTERAE
KARSVNTIKKLKNGTLLGDNTDGIGFISDLKRLNWLDNNNQIISNDAPIPMVTNILLIGAGGAAKGIVPILLTTITTCHI
NIVNRTFSRAQELTSYYQEIGYKNISCLPLYKLRYDTNKYSLIINATTSNIHNTIPKIPYFLITPDTKCYDLFYTKQDTL
FITWCKKNGANYCADGLGMLVGQAAHSFLLWHNTFPTINPVIDHLRSAFYM

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1789675, Length=287, Percent_Identity=46.3414634146341, Blast_Score=255, Evalue=2e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROE_BLOPB (Q493H9)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277734.1
- HSSP:   Q9SQT8
- ProteinModelPortal:   Q493H9
- SMR:   Q493H9
- STRING:   Q493H9
- GeneID:   3562942
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_228
- eggNOG:   COG0169
- HOGENOM:   HBG553408
- OMA:   DQYVVFG
- ProtClustDB:   PRK00258
- BioCyc:   CBLO291272:BPEN_228-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00222
- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151
- Gene3D:   G3DSA:3.40.50.720
- TIGRFAMs:   TIGR00507

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N

EC number: =1.1.1.25

Molecular weight: Translated: 32769; Mature: 32769

Theoretical pI: Translated: 9.06; Mature: 9.06

Prosite motif: NA

Important sites: ACT_SITE 65-65

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFAVFGNPIRHSKSAEIYALFAHEIGISKEYNLKLAVQDNFNYLLHNFFKLGGLGANI
CCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCC
TSPFKENAYFLCNQLTERAEKARSVNTIKKLKNGTLLGDNTDGIGFISDLKRLNWLDNNN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHCCCCCCC
QIISNDAPIPMVTNILLIGAGGAAKGIVPILLTTITTCHINIVNRTFSRAQELTSYYQEI
EEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHH
GYKNISCLPLYKLRYDTNKYSLIINATTSNIHNTIPKIPYFLITPDTKCYDLFYTKQDTL
CCCCCCEEEEEEEEECCCEEEEEEEECCCHHHHHHCCCCEEEECCCCCEEEEEEECCCEE
FITWCKKNGANYCADGLGMLVGQAAHSFLLWHNTFPTINPVIDHLRSAFYM
EEEEEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNSFAVFGNPIRHSKSAEIYALFAHEIGISKEYNLKLAVQDNFNYLLHNFFKLGGLGANI
CCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCC
TSPFKENAYFLCNQLTERAEKARSVNTIKKLKNGTLLGDNTDGIGFISDLKRLNWLDNNN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHCCCCCCC
QIISNDAPIPMVTNILLIGAGGAAKGIVPILLTTITTCHINIVNRTFSRAQELTSYYQEI
EEEECCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHH
GYKNISCLPLYKLRYDTNKYSLIINATTSNIHNTIPKIPYFLITPDTKCYDLFYTKQDTL
CCCCCCEEEEEEEEECCCEEEEEEEECCCHHHHHHCCCCEEEECCCCCEEEEEEECCCEE
FITWCKKNGANYCADGLGMLVGQAAHSFLLWHNTFPTINPVIDHLRSAFYM
EEEEEECCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA