Click here to switch to the map view.

The map label for this gene is dnaQ [H]

Identifier: 71892007

GI number: 71892007

Start: 262500

End: 263249

Strand: Direct

Name: dnaQ [H]

Synonym: BPEN_232

Alternate gene names: 71892007

Gene position: 262500-263249 (Clockwise)

Preceding gene: 71892004

Following gene: 71892008

Centisome position: 33.16

GC content: 29.07

Gene sequence:

>750_bases
ATGAGCACTAATATTATACGACAAATCGTTTTAGATACTGAAACCACTGGCATGAATAAGTTTGGACCACATTATGAAGG
ACATAGGGTTATTGAAATAGGTGCAGTAGAGATAATAAACCGTCATCTAACTGATAACACATTCCATGTTTATTTGAAAC
CAAATCGTATGATTGACATTGAGGCCATTCAGGTACATGGAATTAGCGATCAATTTCTGAAAAATAAACCAATTTTTTCA
GAAATAATAAATGAATTTTTAACATTCATTCGCGGGAGTGAATTAATTATTCATAATGCTTCTTTTGATCTAGGATTTCT
TAATCAAGAATTACGAATTTGCAAGGCAAACTCAAAAAAAATAGAATCTTACTGCACTGTAATTGATAGCTTAAAATTAG
CTCGAAAAAAATTTCCAGGACAACGTAACAGTTTAGATGCATTATGCGAACGTTATTCTATTAATAATGGTAATCGACGA
AATTTACATAGCGCATTACTTGATGCGCGACTTCTAGCTAATGTATTTTTATCTATGAGTGGAGGTCAAATAAAAATGAA
ATTTATGGAAATAATGAATACAAATATATCAAATAATAAAATCAATAATATAATAGGACTAAACAATACAAAATGTATAA
ATAAAAGATCATTAAGAATCATTTATGCTAACGAACAAGAAAAATTAGCTCACGAAGAATATTTAGATAGCATACAGCAG
TTAAATAAATTCTGTATATGGCGACAATAA

Upstream 100 bases:

>100_bases
AAGACATGACCCATCCGTAAAAATTTCTATTTTTTTATACATATTATAGGATATATTATCATTTCAATTTAAATAACTAG
TGTGACACAAATGAAAAGCT

Downstream 100 bases:

>100_bases
TAATGATGTAACAAAATAATAATTTTCAGATTATTTTTTTATAATAAAATAAAACAGTAGATACGTTTGTAAGCAGTATA
AATATACTCTATATTGCAGA

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MSTNIIRQIVLDTETTGMNKFGPHYEGHRVIEIGAVEIINRHLTDNTFHVYLKPNRMIDIEAIQVHGISDQFLKNKPIFS
EIINEFLTFIRGSELIIHNASFDLGFLNQELRICKANSKKIESYCTVIDSLKLARKKFPGQRNSLDALCERYSINNGNRR
NLHSALLDARLLANVFLSMSGGQIKMKFMEIMNTNISNNKINNIIGLNNTKCINKRSLRIIYANEQEKLAHEEYLDSIQQ
LNKFCIWRQ

Sequences:

>Translated_249_residues
MSTNIIRQIVLDTETTGMNKFGPHYEGHRVIEIGAVEIINRHLTDNTFHVYLKPNRMIDIEAIQVHGISDQFLKNKPIFS
EIINEFLTFIRGSELIIHNASFDLGFLNQELRICKANSKKIESYCTVIDSLKLARKKFPGQRNSLDALCERYSINNGNRR
NLHSALLDARLLANVFLSMSGGQIKMKFMEIMNTNISNNKINNIIGLNNTKCINKRSLRIIYANEQEKLAHEEYLDSIQQ
LNKFCIWRQ
>Mature_248_residues
STNIIRQIVLDTETTGMNKFGPHYEGHRVIEIGAVEIINRHLTDNTFHVYLKPNRMIDIEAIQVHGISDQFLKNKPIFSE
IINEFLTFIRGSELIIHNASFDLGFLNQELRICKANSKKIESYCTVIDSLKLARKKFPGQRNSLDALCERYSINNGNRRN
LHSALLDARLLANVFLSMSGGQIKMKFMEIMNTNISNNKINNIIGLNNTKCINKRSLRIIYANEQEKLAHEEYLDSIQQL
NKFCIWRQ

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=249, Percent_Identity=53.0120481927711, Blast_Score=286, Evalue=9e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 28757; Mature: 28626

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNIIRQIVLDTETTGMNKFGPHYEGHRVIEIGAVEIINRHLTDNTFHVYLKPNRMIDI
CCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCEEEEEECCCCEEEE
EAIQVHGISDQFLKNKPIFSEIINEFLTFIRGSELIIHNASFDLGFLNQELRICKANSKK
EEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHEEECCCCHH
IESYCTVIDSLKLARKKFPGQRNSLDALCERYSINNGNRRNLHSALLDARLLANVFLSMS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
GGQIKMKFMEIMNTNISNNKINNIIGLNNTKCINKRSLRIIYANEQEKLAHEEYLDSIQQ
CCEEEHHHHHHHCCCCCCCCCCCEECCCCCCEECCCCEEEEEECCHHHHHHHHHHHHHHH
LNKFCIWRQ
HHHHHCCCC
>Mature Secondary Structure 
STNIIRQIVLDTETTGMNKFGPHYEGHRVIEIGAVEIINRHLTDNTFHVYLKPNRMIDI
CHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHCCCCEEEEEECCCCEEEE
EAIQVHGISDQFLKNKPIFSEIINEFLTFIRGSELIIHNASFDLGFLNQELRICKANSKK
EEEEEECCCHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHEEECCCCHH
IESYCTVIDSLKLARKKFPGQRNSLDALCERYSINNGNRRNLHSALLDARLLANVFLSMS
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCC
GGQIKMKFMEIMNTNISNNKINNIIGLNNTKCINKRSLRIIYANEQEKLAHEEYLDSIQQ
CCEEEHHHHHHHCCCCCCCCCCCEECCCCCCEECCCCEEEEEECCHHHHHHHHHHHHHHH
LNKFCIWRQ
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]