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The map label for this gene is ftsW [H]

Identifier: 71891928

GI number: 71891928

Start: 177780

End: 178976

Strand: Direct

Name: ftsW [H]

Synonym: BPEN_145

Alternate gene names: 71891928

Gene position: 177780-178976 (Clockwise)

Preceding gene: 71891927

Following gene: 71891929

Centisome position: 22.46

GC content: 30.74

Gene sequence:

>1197_bases
ATGAGGCTCTTTAAAACAAAAATTATTAATCGTCCATTAAAATTGGGTAAAAAAAAATCATCAAACATTCATGTATTATA
TGATCGTATATTTTTTTGGTTGCTGTTGGGATTAATTGGAATTGGGTTTGTTATTATTAGTTCCGGATCAATCCCTACTG
GTATGCGATTAGCGAATGATCCATGTTATTTCATAAAACGTGTCATTGTTTATTACAGCGTGACATTTTTATTATCTGTA
ATTATTTTAAAGATACCCATAATAGTTTGGCAGAATTATAGTGCTATAATGTTGCTGTGTAGCTGTATCATGTTGATAAC
CGCATTAATCTTAAATAATTCTACTAATGGAGCATCGCGTTGGATAATGTGGGGTACATTGTGTATTCAGCCTGCGGAAT
TATCAAAATTATCTTTTATTTGCTATCTTGCTAACTATTTAGAACGTAAATCAAAAGAAGTATGTACCAAATTTTGGAGT
ATATGTAAACCTATAGTAATAATGATTATATTAGCTGTATTATTGCTAGCGCAACCTGATTTTGGTAGCATTATTATTCT
TTTTATTACTACTCTGTCTATATTATTTCTTTTTGGCGCTAAGTTATGTCAATTAATATTGGTTTTTGTATTCAATATAT
TTTTAATTATACCTTTAATTGTGATTAAACCTTATCGCATACAACGTATACTTACTTTTTGGGACCCATGGAAAGATCCA
TTTGGCAATGGTTATCAATTAACTCAATCATTAATAGCTTTTGGTCGTGGAAAATGTTTTGGAGAGGGGCTAGGAAATTC
TGTGCTGAAATTAGAATATTTACCTGAAGCTCATACTGATTTTATTTTTTCTATTCTTGCGGAAGAATTAGGATATTTTG
GAGCGATTTTAGTGTTATTTATGTTATTTATAATTGTGCTTCGCGCTATGATTATTGGTCATCGTGCTTTGAATATTAAT
CACAGATTTTCTGGTATTTTAGCCTGTTCTATTAGCATGTGGTTTGGATTGCAAATTTTTATTAATGTGGGCACTGTTAG
CGGAATATTACCTACAAAAGGATTAACATTGCCATTTATTAGTTATGGAGGGTCTAGTTTTTTGATTACAGTAATGGCAA
GCATGCAGTTGCTACGAATAGATTTCGAGACACGTTTATCTAAAAATCAAGCTTTTTTGAAGTGCACAAAAATATGA

Upstream 100 bases:

>100_bases
ATATCGTTTTATTATCTCCGGCTTGTTCTAGTTTAGATCAATTTAAATCATTTGAAATGCGTGGACTGATATTTACTTGT
TTTGCGCGAGAATTTAGATA

Downstream 100 bases:

>100_bases
ATCAAAAAAAGAAAATTATGATTGTAGCGGGTGGTAGTGGGGGGCATGTGTTTCCAGGGTTGTCGGTGGCTCATTATTTA
ATTAATCATGGGTATCAAGT

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRLFKTKIINRPLKLGKKKSSNIHVLYDRIFFWLLLGLIGIGFVIISSGSIPTGMRLANDPCYFIKRVIVYYSVTFLLSV
IILKIPIIVWQNYSAIMLLCSCIMLITALILNNSTNGASRWIMWGTLCIQPAELSKLSFICYLANYLERKSKEVCTKFWS
ICKPIVIMIILAVLLLAQPDFGSIIILFITTLSILFLFGAKLCQLILVFVFNIFLIIPLIVIKPYRIQRILTFWDPWKDP
FGNGYQLTQSLIAFGRGKCFGEGLGNSVLKLEYLPEAHTDFIFSILAEELGYFGAILVLFMLFIIVLRAMIIGHRALNIN
HRFSGILACSISMWFGLQIFINVGTVSGILPTKGLTLPFISYGGSSFLITVMASMQLLRIDFETRLSKNQAFLKCTKI

Sequences:

>Translated_398_residues
MRLFKTKIINRPLKLGKKKSSNIHVLYDRIFFWLLLGLIGIGFVIISSGSIPTGMRLANDPCYFIKRVIVYYSVTFLLSV
IILKIPIIVWQNYSAIMLLCSCIMLITALILNNSTNGASRWIMWGTLCIQPAELSKLSFICYLANYLERKSKEVCTKFWS
ICKPIVIMIILAVLLLAQPDFGSIIILFITTLSILFLFGAKLCQLILVFVFNIFLIIPLIVIKPYRIQRILTFWDPWKDP
FGNGYQLTQSLIAFGRGKCFGEGLGNSVLKLEYLPEAHTDFIFSILAEELGYFGAILVLFMLFIIVLRAMIIGHRALNIN
HRFSGILACSISMWFGLQIFINVGTVSGILPTKGLTLPFISYGGSSFLITVMASMQLLRIDFETRLSKNQAFLKCTKI
>Mature_398_residues
MRLFKTKIINRPLKLGKKKSSNIHVLYDRIFFWLLLGLIGIGFVIISSGSIPTGMRLANDPCYFIKRVIVYYSVTFLLSV
IILKIPIIVWQNYSAIMLLCSCIMLITALILNNSTNGASRWIMWGTLCIQPAELSKLSFICYLANYLERKSKEVCTKFWS
ICKPIVIMIILAVLLLAQPDFGSIIILFITTLSILFLFGAKLCQLILVFVFNIFLIIPLIVIKPYRIQRILTFWDPWKDP
FGNGYQLTQSLIAFGRGKCFGEGLGNSVLKLEYLPEAHTDFIFSILAEELGYFGAILVLFMLFIIVLRAMIIGHRALNIN
HRFSGILACSISMWFGLQIFINVGTVSGILPTKGLTLPFISYGGSSFLITVMASMQLLRIDFETRLSKNQAFLKCTKI

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=381, Percent_Identity=56.6929133858268, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1786853, Length=315, Percent_Identity=33.6507936507937, Blast_Score=157, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 45039; Mature: 45039

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLFKTKIINRPLKLGKKKSSNIHVLYDRIFFWLLLGLIGIGFVIISSGSIPTGMRLAND
CCCHHHHHHCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEECCC
PCYFIKRVIVYYSVTFLLSVIILKIPIIVWQNYSAIMLLCSCIMLITALILNNSTNGASR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
WIMWGTLCIQPAELSKLSFICYLANYLERKSKEVCTKFWSICKPIVIMIILAVLLLAQPD
HEEEHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FGSIIILFITTLSILFLFGAKLCQLILVFVFNIFLIIPLIVIKPYRIQRILTFWDPWKDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
FGNGYQLTQSLIAFGRGKCFGEGLGNSVLKLEYLPEAHTDFIFSILAEELGYFGAILVLF
CCCHHHHHHHHHHHHCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
MLFIIVLRAMIIGHRALNINHRFSGILACSISMWFGLQIFINVGTVSGILPTKGLTLPFI
HHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCHH
SYGGSSFLITVMASMQLLRIDFETRLSKNQAFLKCTKI
HCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHEEEECC
>Mature Secondary Structure
MRLFKTKIINRPLKLGKKKSSNIHVLYDRIFFWLLLGLIGIGFVIISSGSIPTGMRLAND
CCCHHHHHHCCHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEECCC
PCYFIKRVIVYYSVTFLLSVIILKIPIIVWQNYSAIMLLCSCIMLITALILNNSTNGASR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCH
WIMWGTLCIQPAELSKLSFICYLANYLERKSKEVCTKFWSICKPIVIMIILAVLLLAQPD
HEEEHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FGSIIILFITTLSILFLFGAKLCQLILVFVFNIFLIIPLIVIKPYRIQRILTFWDPWKDP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCC
FGNGYQLTQSLIAFGRGKCFGEGLGNSVLKLEYLPEAHTDFIFSILAEELGYFGAILVLF
CCCHHHHHHHHHHHHCCCCHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
MLFIIVLRAMIIGHRALNINHRFSGILACSISMWFGLQIFINVGTVSGILPTKGLTLPFI
HHHHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCHH
SYGGSSFLITVMASMQLLRIDFETRLSKNQAFLKCTKI
HCCCHHHHHHHHHHHHHHHCCHHHHHCCCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]