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The map label for this gene is murG

Identifier: 71891929

GI number: 71891929

Start: 178973

End: 180040

Strand: Direct

Name: murG

Synonym: BPEN_146

Alternate gene names: 71891929

Gene position: 178973-180040 (Clockwise)

Preceding gene: 71891928

Following gene: 71891930

Centisome position: 22.61

GC content: 35.21

Gene sequence:

>1068_bases
ATGAATCAAAAAAAGAAAATTATGATTGTAGCGGGTGGTAGTGGGGGGCATGTGTTTCCAGGGTTGTCGGTGGCTCATTA
TTTAATTAATCATGGGTATCAAGTTGTTTGGCTAGGTACTGCAGATCGCATTGAATCGAAGTTAGTTCCTCAATATGGAA
TCGATATTAAATTTATTCGTATTAACGGATGGAATGGTGAAAAATTACATATTAAGTGTATTATGCCATTGTTTATTTGT
TTAGCAATATATCAAGCACGAAAAATTATAAAATATTGGAAACCTGATATAGTATTAGGTATGGGTGGATATGTTTCCGG
ACCCGGTGGATTAGCAGCATGGACATGCGGTGTTCCATTGATAATACACGAACAAAATAGAATTATCGGTTTAACTAATC
GGTATTTATCAATTTTTTCTAAAAAAGTATTGCAAGGATTTCCTGGTACTTTTCCTAATGCTAAAATGGTAGGAAACCCA
ATACGACGAGCAATATTAGCTGTTCCAAATCCATCTAGACGATGGAAAGGTCGTGTTGGTCCTATTCGTGTTTTAGTGAT
TGGAGGCAGTCAAGGCGCGCATATATTAAATAAAACTATCCCAAATATGGCTGAGAAATTGTCTGATAAATTGATCATAT
GGCACCAAGTTGGAGAACAAGATTTCAAAAAAGTAATATGGGCTTATCAAAAAATAAAACAAAGCTATCATAGAATTGTA
AAATTTATTGATGATATAGCCCAAGCATATGCTTGGGCAGATATATTGATATCCCGTGCTGGAGCATTAACAGTAAGCGA
AGTATCTATTGTAGGGTTACCAGCAATATTTGTACCTTTTATACATCATAAAGATCGTCAGCAATATTGGAATGCCGTGC
CATTAGTGCAAGCAGGAGCAGCAAAAATTATTGAACAAAAAAATTTTACAAGTGATGTTGTTAGCGCAATGTTAGAATCT
TGGGATCGAAAAACATTATGTAGTATGGCTCAACGTGCTAGAAGCATAGCTGCGCCTAATGCAACTCAACAAGTTTCCCA
AGTAATCATTGAATACTTAAAAAAATAA

Upstream 100 bases:

>100_bases
CTAGTTTTTTGATTACAGTAATGGCAAGCATGCAGTTGCTACGAATAGATTTCGAGACACGTTTATCTAAAAATCAAGCT
TTTTTGAAGTGCACAAAAAT

Downstream 100 bases:

>100_bases
ATATATTAATAATGTCATCTTTATAAATAGAAAAATATTGAAAGTATATTGAATAGATATGTCAGGCATACTATTATCTA
ACCCGGTCAATGCTATACCA

Product: UDP-N-acetylglucosamine:N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MNQKKKIMIVAGGSGGHVFPGLSVAHYLINHGYQVVWLGTADRIESKLVPQYGIDIKFIRINGWNGEKLHIKCIMPLFIC
LAIYQARKIIKYWKPDIVLGMGGYVSGPGGLAAWTCGVPLIIHEQNRIIGLTNRYLSIFSKKVLQGFPGTFPNAKMVGNP
IRRAILAVPNPSRRWKGRVGPIRVLVIGGSQGAHILNKTIPNMAEKLSDKLIIWHQVGEQDFKKVIWAYQKIKQSYHRIV
KFIDDIAQAYAWADILISRAGALTVSEVSIVGLPAIFVPFIHHKDRQQYWNAVPLVQAGAAKIIEQKNFTSDVVSAMLES
WDRKTLCSMAQRARSIAAPNATQQVSQVIIEYLKK

Sequences:

>Translated_355_residues
MNQKKKIMIVAGGSGGHVFPGLSVAHYLINHGYQVVWLGTADRIESKLVPQYGIDIKFIRINGWNGEKLHIKCIMPLFIC
LAIYQARKIIKYWKPDIVLGMGGYVSGPGGLAAWTCGVPLIIHEQNRIIGLTNRYLSIFSKKVLQGFPGTFPNAKMVGNP
IRRAILAVPNPSRRWKGRVGPIRVLVIGGSQGAHILNKTIPNMAEKLSDKLIIWHQVGEQDFKKVIWAYQKIKQSYHRIV
KFIDDIAQAYAWADILISRAGALTVSEVSIVGLPAIFVPFIHHKDRQQYWNAVPLVQAGAAKIIEQKNFTSDVVSAMLES
WDRKTLCSMAQRARSIAAPNATQQVSQVIIEYLKK
>Mature_355_residues
MNQKKKIMIVAGGSGGHVFPGLSVAHYLINHGYQVVWLGTADRIESKLVPQYGIDIKFIRINGWNGEKLHIKCIMPLFIC
LAIYQARKIIKYWKPDIVLGMGGYVSGPGGLAAWTCGVPLIIHEQNRIIGLTNRYLSIFSKKVLQGFPGTFPNAKMVGNP
IRRAILAVPNPSRRWKGRVGPIRVLVIGGSQGAHILNKTIPNMAEKLSDKLIIWHQVGEQDFKKVIWAYQKIKQSYHRIV
KFIDDIAQAYAWADILISRAGALTVSEVSIVGLPAIFVPFIHHKDRQQYWNAVPLVQAGAAKIIEQKNFTSDVVSAMLES
WDRKTLCSMAQRARSIAAPNATQQVSQVIIEYLKK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=348, Percent_Identity=57.183908045977, Blast_Score=432, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_BLOPB (Q493Q1)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277659.1
- ProteinModelPortal:   Q493Q1
- SMR:   Q493Q1
- STRING:   Q493Q1
- GeneID:   3562868
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_146
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- BioCyc:   CBLO291272:BPEN_146-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 39653; Mature: 39653

Theoretical pI: Translated: 10.59; Mature: 10.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQKKKIMIVAGGSGGHVFPGLSVAHYLINHGYQVVWLGTADRIESKLVPQYGIDIKFIR
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCEEEEEE
INGWNGEKLHIKCIMPLFICLAIYQARKIIKYWKPDIVLGMGGYVSGPGGLAAWTCGVPL
EECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECCCCCCEEHHCCCEE
IIHEQNRIIGLTNRYLSIFSKKVLQGFPGTFPNAKMVGNPIRRAILAVPNPSRRWKGRVG
EEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHEEECCCCCHHCCCCCC
PIRVLVIGGSQGAHILNKTIPNMAEKLSDKLIIWHQVGEQDFKKVIWAYQKIKQSYHRIV
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KFIDDIAQAYAWADILISRAGALTVSEVSIVGLPAIFVPFIHHKDRQQYWNAVPLVQAGA
HHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHCCCCHHHHHCCCCHHHHHH
AKIIEQKNFTSDVVSAMLESWDRKTLCSMAQRARSIAAPNATQQVSQVIIEYLKK
HHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQKKKIMIVAGGSGGHVFPGLSVAHYLINHGYQVVWLGTADRIESKLVPQYGIDIKFIR
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCEEEEEE
INGWNGEKLHIKCIMPLFICLAIYQARKIIKYWKPDIVLGMGGYVSGPGGLAAWTCGVPL
EECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEECCCCCCEEHHCCCEE
IIHEQNRIIGLTNRYLSIFSKKVLQGFPGTFPNAKMVGNPIRRAILAVPNPSRRWKGRVG
EEECCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHEEECCCCCHHCCCCCC
PIRVLVIGGSQGAHILNKTIPNMAEKLSDKLIIWHQVGEQDFKKVIWAYQKIKQSYHRIV
CEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
KFIDDIAQAYAWADILISRAGALTVSEVSIVGLPAIFVPFIHHKDRQQYWNAVPLVQAGA
HHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHCCHHHHHHHHCCCCHHHHHCCCCHHHHHH
AKIIEQKNFTSDVVSAMLESWDRKTLCSMAQRARSIAAPNATQQVSQVIIEYLKK
HHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA