Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 71891926

GI number: 71891926

Start: 175365

End: 176453

Strand: Direct

Name: mraY

Synonym: BPEN_143

Alternate gene names: 71891926

Gene position: 175365-176453 (Clockwise)

Preceding gene: 71891925

Following gene: 71891927

Centisome position: 22.15

GC content: 31.04

Gene sequence:

>1089_bases
ATGTTATTTTGGCTAACAGAGAATGTATTAGCACTATATTCATCCAGATTTAATATTGTTTGTCATTTAACTTTCAGAGC
TATTATTAGTTTTTTATCAGCATTGTTTATTTCTTTAGGGATAGGTCATTGTGTAATTACATGGTTTCATAATTTGTGTT
TTTTTCAAATAGTGCGTTGTGATGGACCAAAATCACATACTCAAAAGCAAAGTACACCTACTATGGGTGGAATTGTGCTG
ATTCTTTCTATTGTCATATCAGTAATGGTGTGCGCTGATTTATCAAATATATATGTATGGTATGTATTTTTCATACTAAT
AACATACGGAATATTGGGTTTAACTGACGACATTTTAAAAATTAAAAAGAAAAGTTCTAAGGGTTTGAGTGTGTTACATA
AATACTTTTGGCAATCCTTAATTGCTTTAACATTAGTCATTATTATCTTTATGTCAGATCGCAGTCTTACATCTACACAA
TTAATAGTGCCATTTTTTAAAAATTTTATGCCTCAATTGGGTATTTGGTATATTTTTTTAGCATATTTCGTTGTTGTTGG
GACAAGTAATGCCGTGAATTTATCTGATGGTTTAGATGGGTTAGCGATTATGCCTATAATGTTCGTTGCAGCTGGATTGG
CTGTAGTTGCATGGATAAGCAATGATATTCACTTTGCTAGTCATCTAAATATTCCTTATATTTGCTTTTCTGGAGAATTA
ATAATTATATGTTCTGCTATTATTGGAGCTGGTCTTGGGTTTTTATGGTTTAACACTTATCCTGCTCAGATATTTATGGG
CGATGTAGGTTCTTTATCACTTGGAGGTACACTTGGGATAATTGCAGTGTTGTTACATCAAGAATGTTTATTATTAATTA
TGGGCGGTATGTTTGTAATAGAAACTTTATCTGTGATCTTACAAGTAATTTATTTTAGATTATTTGGGCAACGGATATTT
AAAATGGCACCAATTCATCATCATTTTGAACTAAAAGGTTGTCCAGAACCCCGTATTATAGTGCGATTTTGGATCATATC
TTTAATGTTAGTTTTTGTAGGATTAATTACTTTAAAGATACGGCAATAA

Upstream 100 bases:

>100_bases
AGCAGATGTTATCTATCCATAATTCAATTAGTGTATTAGTAAAAGGATCACGAGGCTTTAAAATGGAGCAAATAATAAAT
GCTATTCGAGATGAATCAAA

Downstream 100 bases:

>100_bases
AAATATGCGTAATTACCGAGGATCAAAAGTTGTAATTATCGGTTTGGGGATTACGGGTTTATCTTGTGTTAATTTTTTTT
TAGATCGTGGCGTAATACCG

Product: phospho-N-acetylmuramoyl-pentapeptide transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MLFWLTENVLALYSSRFNIVCHLTFRAIISFLSALFISLGIGHCVITWFHNLCFFQIVRCDGPKSHTQKQSTPTMGGIVL
ILSIVISVMVCADLSNIYVWYVFFILITYGILGLTDDILKIKKKSSKGLSVLHKYFWQSLIALTLVIIIFMSDRSLTSTQ
LIVPFFKNFMPQLGIWYIFLAYFVVVGTSNAVNLSDGLDGLAIMPIMFVAAGLAVVAWISNDIHFASHLNIPYICFSGEL
IIICSAIIGAGLGFLWFNTYPAQIFMGDVGSLSLGGTLGIIAVLLHQECLLLIMGGMFVIETLSVILQVIYFRLFGQRIF
KMAPIHHHFELKGCPEPRIIVRFWIISLMLVFVGLITLKIRQ

Sequences:

>Translated_362_residues
MLFWLTENVLALYSSRFNIVCHLTFRAIISFLSALFISLGIGHCVITWFHNLCFFQIVRCDGPKSHTQKQSTPTMGGIVL
ILSIVISVMVCADLSNIYVWYVFFILITYGILGLTDDILKIKKKSSKGLSVLHKYFWQSLIALTLVIIIFMSDRSLTSTQ
LIVPFFKNFMPQLGIWYIFLAYFVVVGTSNAVNLSDGLDGLAIMPIMFVAAGLAVVAWISNDIHFASHLNIPYICFSGEL
IIICSAIIGAGLGFLWFNTYPAQIFMGDVGSLSLGGTLGIIAVLLHQECLLLIMGGMFVIETLSVILQVIYFRLFGQRIF
KMAPIHHHFELKGCPEPRIIVRFWIISLMLVFVGLITLKIRQ
>Mature_362_residues
MLFWLTENVLALYSSRFNIVCHLTFRAIISFLSALFISLGIGHCVITWFHNLCFFQIVRCDGPKSHTQKQSTPTMGGIVL
ILSIVISVMVCADLSNIYVWYVFFILITYGILGLTDDILKIKKKSSKGLSVLHKYFWQSLIALTLVIIIFMSDRSLTSTQ
LIVPFFKNFMPQLGIWYIFLAYFVVVGTSNAVNLSDGLDGLAIMPIMFVAAGLAVVAWISNDIHFASHLNIPYICFSGEL
IIICSAIIGAGLGFLWFNTYPAQIFMGDVGSLSLGGTLGIIAVLLHQECLLLIMGGMFVIETLSVILQVIYFRLFGQRIF
KMAPIHHHFELKGCPEPRIIVRFWIISLMLVFVGLITLKIRQ

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=361, Percent_Identity=62.8808864265928, Blast_Score=455, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_BLOPB (Q493Q4)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277656.1
- STRING:   Q493Q4
- GeneID:   3562865
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_143
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   LRQGKGQ
- BioCyc:   CBLO291272:BPEN_143-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4

EC number: =2.7.8.13

Molecular weight: Translated: 40610; Mature: 40610

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10b5b860)-; HASH(0x11647af4)-; HASH(0x1081f134)-; HASH(0x116479e0)-; HASH(0x11647914)-; HASH(0x105fb0ec)-; HASH(0x10de08d4)-; HASH(0x1116c4b4)-; HASH(0x105fb1b8)-; HASH(0x11647c74)-;

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFWLTENVLALYSSRFNIVCHLTFRAIISFLSALFISLGIGHCVITWFHNLCFFQIVRC
CEEEEHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGPKSHTQKQSTPTMGGIVLILSIVISVMVCADLSNIYVWYVFFILITYGILGLTDDILK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IKKKSSKGLSVLHKYFWQSLIALTLVIIIFMSDRSLTSTQLIVPFFKNFMPQLGIWYIFL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AYFVVVGTSNAVNLSDGLDGLAIMPIMFVAAGLAVVAWISNDIHFASHLNIPYICFSGEL
HHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCCEEEECCCH
IIICSAIIGAGLGFLWFNTYPAQIFMGDVGSLSLGGTLGIIAVLLHQECLLLIMGGMFVI
HHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETLSVILQVIYFRLFGQRIFKMAPIHHHFELKGCPEPRIIVRFWIISLMLVFVGLITLKI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RQ
CH
>Mature Secondary Structure
MLFWLTENVLALYSSRFNIVCHLTFRAIISFLSALFISLGIGHCVITWFHNLCFFQIVRC
CEEEEHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DGPKSHTQKQSTPTMGGIVLILSIVISVMVCADLSNIYVWYVFFILITYGILGLTDDILK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
IKKKSSKGLSVLHKYFWQSLIALTLVIIIFMSDRSLTSTQLIVPFFKNFMPQLGIWYIFL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AYFVVVGTSNAVNLSDGLDGLAIMPIMFVAAGLAVVAWISNDIHFASHLNIPYICFSGEL
HHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHHCCCCCEEEECCCH
IIICSAIIGAGLGFLWFNTYPAQIFMGDVGSLSLGGTLGIIAVLLHQECLLLIMGGMFVI
HHHHHHHHHCCHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ETLSVILQVIYFRLFGQRIFKMAPIHHHFELKGCPEPRIIVRFWIISLMLVFVGLITLKI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHC
RQ
CH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA