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The map label for this gene is ctaD [H]

Identifier: 68535551

GI number: 68535551

Start: 585405

End: 587102

Strand: Direct

Name: ctaD [H]

Synonym: jk0481

Alternate gene names: 68535551

Gene position: 585405-587102 (Clockwise)

Preceding gene: 68535550

Following gene: 68535553

Centisome position: 23.77

GC content: 60.37

Gene sequence:

>1698_bases
ATGACCGCAGTAGCGCCTAGGGAAAGCCATGAGGTTTCCCCGGCTCGGCCTGCGCCTTTCGGTGAGGCACCGCGTGGCAG
CCTCGCATGGAAGATGCTGACCACGACCGACCACAAGCTTCTGGGCATCATGTACCTAATCATGTCCTTCACCTTCTTTA
TGGTTGGTGGCTTGATGGCCCTGCTGATCCGTCTCGAGCTTTTCGCGCCGGGCCAGCAATTCCTGTCCAATGAGCAGTTC
AACCAGCTGTTCACCATGCACGGCACGATCATGCTGCTGCTGTACGGCTCCCTGATGGTGTTCGGTTTCGCGAACTACAT
CCTGCCGCTGCAGATCGGCGCGCCTGACGTGGCATTCCCCCGTCTGAACGCCTTCGGCTTCTGGATGACCACCGCCGGTG
GTGTCGTTATGCTGCTCGGCTTCCTGACCCCGGGTGGTGCTGCTGACTTCGGTTGGACCATGTACATGCCGCTGGCGGAC
GCTACGCACTCTCCGGGTGTGGGCTCTGAGCTGTGGATCCTGGGCGTCGGCGTTGGTGGTATCGGTACCATCGCTTCCGC
TGTGAACATGATCACCACCATCCTGTGCCTGCGCGCACCGGGTATGACCATGTTCCGCATGCCGATCTTCACCTGGAACA
TCCTGGTTACCTCTCTGCTGGTTCTGCTGATCTTCCCGCTGCTGACCGCTGCAGCCCTGGGTGTCTTCTACGACCGCAAG
CTGGGTGGCCACATCTACGACGCCGGCAACGGCGGCGCTATCCTGTGGCAGCACCTGTTCTGGTTCTTCGGCCACCCTGA
GGTTTACGTCCTGGCACTGCCGTTCTTCGGCATCGTGTCCGAGGTCTTCCCGGTGTTCTCCCGCAAGCCGATGTTCGGCT
ACGTCGGCCTGGTGTTCGCAACCCTGTCGATTGCTGCACTGTCCATGGCCGTGTGGGCGCACCACATGTTCGTGACCGGC
GCCGTGCTGCTGCCGTTCTTCTCCTTCATGACGTTCCTGATTGCTGTGCCGACCGGTATGAAGTTCTTCAACTGGCTGGG
CACGATGTGGAAGGGCCGTTTGACCTTCGAGACTCCGATGACCTTCGCCATCGGCTTCTACGCCACCTTCCTCTTCGGTG
GTCTGACCGGTGTCATGCTGGCATCCCCGGCGCTGGACTTCCAGGTCTCGGATTCCTACTTCGTGGTTGCTCACTTCCAC
TACACGCTGTTCGGTACCGTGACCTACGCCTCCTTCGCTGGCATCTACTTCTGGTTCCCGAAGATGACCGGTCGCATGCT
GGACGAGAAGCTGGGCAAGATCCACTTCTGGCTGGTTACCATCGGCTTCCACACCACCTTCCTGGTGCAGCACTGGCTGG
GCAACATGGGTATGCCACGTCGTTACGCTGATTACCTGCCGACGGATGGTTTCACCACCCTGAACCAGGTCTCCACGATT
GGTGCCTGCATCCTGGCGATCTCCATGATTCCGTTCCTGTGGAACGTCTTTAAGTCCTACCGCTACGGCGAGGTCGTCAC
TGTTGATGACCCGTGGGGCTACGGAAACTCCCTGGAGTGGGCAACCTCTTGCCCGCCGCCGCGCCACAACTTCAACTCCA
TGCCTCGCATCCGCTCCGAGCGCCCGGCGTTCGAGCTGCACCACCCGCACATGGTCAAGCGCATGCGCGACGAGGCTCAC
GTTGGTCGCCACTTCTAA

Upstream 100 bases:

>100_bases
AGAGGAAACATTCTTTTGGGTGACCGGCTCAAAGAATCCTGTGAGTTATTTAATGCTCGCAAGAGGAAAAGGGCAGGTCA
CGCGTAGTCAGGAGGAACTA

Downstream 100 bases:

>100_bases
GCGCACTTTCTAGTGACGCCCCCTCACCCGGCCACTGCCCAGCGCAGTCGCTAGGTGCCTGGCGGCTGACCCGGTCTTAA
AATCCACACCTCAACTACGC

Product: cytochrome c oxidase subunit I

Products: NA

Alternate protein names: Cytochrome aa3 subunit 1; Cytochrome c oxidase polypeptide I [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MTAVAPRESHEVSPARPAPFGEAPRGSLAWKMLTTTDHKLLGIMYLIMSFTFFMVGGLMALLIRLELFAPGQQFLSNEQF
NQLFTMHGTIMLLLYGSLMVFGFANYILPLQIGAPDVAFPRLNAFGFWMTTAGGVVMLLGFLTPGGAADFGWTMYMPLAD
ATHSPGVGSELWILGVGVGGIGTIASAVNMITTILCLRAPGMTMFRMPIFTWNILVTSLLVLLIFPLLTAAALGVFYDRK
LGGHIYDAGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVFPVFSRKPMFGYVGLVFATLSIAALSMAVWAHHMFVTG
AVLLPFFSFMTFLIAVPTGMKFFNWLGTMWKGRLTFETPMTFAIGFYATFLFGGLTGVMLASPALDFQVSDSYFVVAHFH
YTLFGTVTYASFAGIYFWFPKMTGRMLDEKLGKIHFWLVTIGFHTTFLVQHWLGNMGMPRRYADYLPTDGFTTLNQVSTI
GACILAISMIPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFNSMPRIRSERPAFELHHPHMVKRMRDEAH
VGRHF

Sequences:

>Translated_565_residues
MTAVAPRESHEVSPARPAPFGEAPRGSLAWKMLTTTDHKLLGIMYLIMSFTFFMVGGLMALLIRLELFAPGQQFLSNEQF
NQLFTMHGTIMLLLYGSLMVFGFANYILPLQIGAPDVAFPRLNAFGFWMTTAGGVVMLLGFLTPGGAADFGWTMYMPLAD
ATHSPGVGSELWILGVGVGGIGTIASAVNMITTILCLRAPGMTMFRMPIFTWNILVTSLLVLLIFPLLTAAALGVFYDRK
LGGHIYDAGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVFPVFSRKPMFGYVGLVFATLSIAALSMAVWAHHMFVTG
AVLLPFFSFMTFLIAVPTGMKFFNWLGTMWKGRLTFETPMTFAIGFYATFLFGGLTGVMLASPALDFQVSDSYFVVAHFH
YTLFGTVTYASFAGIYFWFPKMTGRMLDEKLGKIHFWLVTIGFHTTFLVQHWLGNMGMPRRYADYLPTDGFTTLNQVSTI
GACILAISMIPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFNSMPRIRSERPAFELHHPHMVKRMRDEAH
VGRHF
>Mature_564_residues
TAVAPRESHEVSPARPAPFGEAPRGSLAWKMLTTTDHKLLGIMYLIMSFTFFMVGGLMALLIRLELFAPGQQFLSNEQFN
QLFTMHGTIMLLLYGSLMVFGFANYILPLQIGAPDVAFPRLNAFGFWMTTAGGVVMLLGFLTPGGAADFGWTMYMPLADA
THSPGVGSELWILGVGVGGIGTIASAVNMITTILCLRAPGMTMFRMPIFTWNILVTSLLVLLIFPLLTAAALGVFYDRKL
GGHIYDAGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVFPVFSRKPMFGYVGLVFATLSIAALSMAVWAHHMFVTGA
VLLPFFSFMTFLIAVPTGMKFFNWLGTMWKGRLTFETPMTFAIGFYATFLFGGLTGVMLASPALDFQVSDSYFVVAHFHY
TLFGTVTYASFAGIYFWFPKMTGRMLDEKLGKIHFWLVTIGFHTTFLVQHWLGNMGMPRRYADYLPTDGFTTLNQVSTIG
ACILAISMIPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFNSMPRIRSERPAFELHHPHMVKRMRDEAHV
GRHF

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome

COG id: COG0843

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heme-copper respiratory oxidase family [H]

Homologues:

Organism=Homo sapiens, GI251831109, Length=517, Percent_Identity=40.6189555125725, Blast_Score=355, Evalue=5e-98,
Organism=Escherichia coli, GI1786634, Length=524, Percent_Identity=43.3206106870229, Blast_Score=396, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6226519, Length=535, Percent_Identity=38.6915887850467, Blast_Score=350, Evalue=3e-97,
Organism=Saccharomyces cerevisiae, GI6226524, Length=320, Percent_Identity=40.9375, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6226523, Length=246, Percent_Identity=37.3983739837398, Blast_Score=144, Evalue=4e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000883
- InterPro:   IPR014241 [H]

Pfam domain/function: PF00115 COX1 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 63101; Mature: 62970

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50855 COX1 ; PS00077 COX1_CUB ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVAPRESHEVSPARPAPFGEAPRGSLAWKMLTTTDHKLLGIMYLIMSFTFFMVGGLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LLIRLELFAPGQQFLSNEQFNQLFTMHGTIMLLLYGSLMVFGFANYILPLQIGAPDVAFP
HHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCC
RLNAFGFWMTTAGGVVMLLGFLTPGGAADFGWTMYMPLADATHSPGVGSELWILGVGVGG
CCCHHEEHHHHHCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCH
IGTIASAVNMITTILCLRAPGMTMFRMPIFTWNILVTSLLVLLIFPLLTAAALGVFYDRK
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHIYDAGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVFPVFSRKPMFGYVGLVFA
CCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TLSIAALSMAVWAHHMFVTGAVLLPFFSFMTFLIAVPTGMKFFNWLGTMWKGRLTFETPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCH
TFAIGFYATFLFGGLTGVMLASPALDFQVSDSYFVVAHFHYTLFGTVTYASFAGIYFWFP
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
KMTGRMLDEKLGKIHFWLVTIGFHTTFLVQHWLGNMGMPRRYADYLPTDGFTTLNQVSTI
HHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHH
GACILAISMIPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFNSMPRIRSE
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPAFELHHPHMVKRMRDEAHVGRHF
CCCEECCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TAVAPRESHEVSPARPAPFGEAPRGSLAWKMLTTTDHKLLGIMYLIMSFTFFMVGGLMA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
LLIRLELFAPGQQFLSNEQFNQLFTMHGTIMLLLYGSLMVFGFANYILPLQIGAPDVAFP
HHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCC
RLNAFGFWMTTAGGVVMLLGFLTPGGAADFGWTMYMPLADATHSPGVGSELWILGVGVGG
CCCHHEEHHHHHCHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCH
IGTIASAVNMITTILCLRAPGMTMFRMPIFTWNILVTSLLVLLIFPLLTAAALGVFYDRK
HHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
LGGHIYDAGNGGAILWQHLFWFFGHPEVYVLALPFFGIVSEVFPVFSRKPMFGYVGLVFA
CCCEEEECCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHH
TLSIAALSMAVWAHHMFVTGAVLLPFFSFMTFLIAVPTGMKFFNWLGTMWKGRLTFETPM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCH
TFAIGFYATFLFGGLTGVMLASPALDFQVSDSYFVVAHFHYTLFGTVTYASFAGIYFWFP
HHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCEEEEEEEHHHHHHHHHHHHHHHHHHHHH
KMTGRMLDEKLGKIHFWLVTIGFHTTFLVQHWLGNMGMPRRYADYLPTDGFTTLNQVSTI
HHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHHHHH
GACILAISMIPFLWNVFKSYRYGEVVTVDDPWGYGNSLEWATSCPPPRHNFNSMPRIRSE
HHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RPAFELHHPHMVKRMRDEAHVGRHF
CCCEECCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14602910 [H]