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The map label for this gene is fadE3 [H]

Identifier: 68535360

GI number: 68535360

Start: 359226

End: 360644

Strand: Direct

Name: fadE3 [H]

Synonym: jk0295

Alternate gene names: 68535360

Gene position: 359226-360644 (Clockwise)

Preceding gene: 68535359

Following gene: 68535361

Centisome position: 14.59

GC content: 64.69

Gene sequence:

>1419_bases
ATGAGCGACCGAAGCAAGCGTGCCGATTCGACTCCTGGCCTGAACAACATCAAGCGAGACGCAATCGGTACCGTCATGGG
AGTCTTGACGAAGTTCACCGGCTCCGACCTGGCAGAGAAGTATGGTCTGAGCAAGAAGGTGGACCGCGTTGCCTACCAGT
CCACTAAGACCGGCATGCGCACCCTCGGTGCCGTGAACCGCCAGTTCAAGAAGATCAAGGGCTCCGGCAAGCCGGTACGT
CTGGCTAACCAGACCACCGACGAAAACAACCAGCCTGTCCCGACCGAGGCGCCGGCACCGGGCAAGGCACCGTTCGACCT
GACCCCGACTGAGGATCAGGAAATGATCGTCGCAGCCGTACGCGAGTTCGCTGAAGAGCGCCTGCGTCCGACCGGCCACG
ACCAGAACGAGGCATCTGAGCCGGCAGAGGGGCTGCTGGAAGCTGCTGCTGAGCTGGGCGTTGCCCTGATCAACCTGCCG
GAAGAGTACGAGGGCATTGCCTCCGCCTCCGGCGCCACCACCAACGCGTTGATCGCCGAGGCTCTGGCATTCGGAGACAT
GGGCCAGGCCGTAGCAATCCTGGCACCGGCCGGCGTGGCCAACGTCATCACCAACTACGGTGACGACTCCCAGCAGAAGA
CCTACCTGCCGGAGTTTGCAGGCGAGTCCGTCCCGGCTTCCGCAGTGGTCGTTTCCGAGTCCCGCCCGCTGTTCGACCCC
TTCACCCTGCAGACCACCGCCGTCCGCGAGGGCGACGACATCGTCATCAACGGTGTGAAGACCATGGTTCCGAACGCAGG
CAAGGCCGAGCTGTTCGTCATCGCAGTGAACCTCGACGGCGAGAACACCTTCGTCATCGTCGAGTCCGACACCGAGGGAC
TGGTCGTTGAGGCTGACCCGTCCATGGGCCTGCGCGGCGCTGCCCTGGGCCGCCTCCTGCTGAAGGATGTCCGCGTTCCC
GCCAGCCAGCTGCTGGGTGGCAAGGACCTGGCCGCTGACGAGCGCAAGGAAAACTACGCGGAGATCATCCGCCGCTCCCG
CTTGGGCTGGGCCGCACTGGCAGCCGGCACCGGCGAGGCAATCCTGGAGTACACCAAGAAGTACGTCAACGAGCGCGAAG
CATTCGGCGAGCCGATCTCGCACCGCCAGGCAGTGGCCTTCATGGTCGCCAACCTGCGCATCGAGCTCGACGGCCTGCGC
CTGATCCTGCTGCGCGGTGTATCCCGCCTGGATCAGGGCCTGTCCTTCAACCGCGAAGCCGGTCTTGCCCGCCGCTACGC
ATCCGACAAGGGCATGGTTATGGGCCTCGACGGTGTGCAGCTGCTCGGTGGCCACGGCTTCACCAAGGAGCACCCGGTCG
AGCGCTGGTACCGCGACATGCGCGCCATCGGCATCGCCGAGGGCGTAGTCGTCGTCTAA

Upstream 100 bases:

>100_bases
GTGATGCGCGCCATTATTCTGGTTTATGCTACGTACATAATTATCCGCACATGCAGATATGAGATTTGCGCTGACAACCA
GTGAAAGGTGGCCGCACGAA

Downstream 100 bases:

>100_bases
CCCCGCCACAATTCGAATCCATATCGAATAAGCACAAGGAACTTCAAGGAACCACATCATGATTAATCTGGAACTCCCCA
AGCGTTTGAAGGCGGGCCAG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSDRSKRADSTPGLNNIKRDAIGTVMGVLTKFTGSDLAEKYGLSKKVDRVAYQSTKTGMRTLGAVNRQFKKIKGSGKPVR
LANQTTDENNQPVPTEAPAPGKAPFDLTPTEDQEMIVAAVREFAEERLRPTGHDQNEASEPAEGLLEAAAELGVALINLP
EEYEGIASASGATTNALIAEALAFGDMGQAVAILAPAGVANVITNYGDDSQQKTYLPEFAGESVPASAVVVSESRPLFDP
FTLQTTAVREGDDIVINGVKTMVPNAGKAELFVIAVNLDGENTFVIVESDTEGLVVEADPSMGLRGAALGRLLLKDVRVP
ASQLLGGKDLAADERKENYAEIIRRSRLGWAALAAGTGEAILEYTKKYVNEREAFGEPISHRQAVAFMVANLRIELDGLR
LILLRGVSRLDQGLSFNREAGLARRYASDKGMVMGLDGVQLLGGHGFTKEHPVERWYRDMRAIGIAEGVVVV

Sequences:

>Translated_472_residues
MSDRSKRADSTPGLNNIKRDAIGTVMGVLTKFTGSDLAEKYGLSKKVDRVAYQSTKTGMRTLGAVNRQFKKIKGSGKPVR
LANQTTDENNQPVPTEAPAPGKAPFDLTPTEDQEMIVAAVREFAEERLRPTGHDQNEASEPAEGLLEAAAELGVALINLP
EEYEGIASASGATTNALIAEALAFGDMGQAVAILAPAGVANVITNYGDDSQQKTYLPEFAGESVPASAVVVSESRPLFDP
FTLQTTAVREGDDIVINGVKTMVPNAGKAELFVIAVNLDGENTFVIVESDTEGLVVEADPSMGLRGAALGRLLLKDVRVP
ASQLLGGKDLAADERKENYAEIIRRSRLGWAALAAGTGEAILEYTKKYVNEREAFGEPISHRQAVAFMVANLRIELDGLR
LILLRGVSRLDQGLSFNREAGLARRYASDKGMVMGLDGVQLLGGHGFTKEHPVERWYRDMRAIGIAEGVVVV
>Mature_471_residues
SDRSKRADSTPGLNNIKRDAIGTVMGVLTKFTGSDLAEKYGLSKKVDRVAYQSTKTGMRTLGAVNRQFKKIKGSGKPVRL
ANQTTDENNQPVPTEAPAPGKAPFDLTPTEDQEMIVAAVREFAEERLRPTGHDQNEASEPAEGLLEAAAELGVALINLPE
EYEGIASASGATTNALIAEALAFGDMGQAVAILAPAGVANVITNYGDDSQQKTYLPEFAGESVPASAVVVSESRPLFDPF
TLQTTAVREGDDIVINGVKTMVPNAGKAELFVIAVNLDGENTFVIVESDTEGLVVEADPSMGLRGAALGRLLLKDVRVPA
SQLLGGKDLAADERKENYAEIIRRSRLGWAALAAGTGEAILEYTKKYVNEREAFGEPISHRQAVAFMVANLRIELDGLRL
ILLRGVSRLDQGLSFNREAGLARRYASDKGMVMGLDGVQLLGGHGFTKEHPVERWYRDMRAIGIAEGVVVV

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=30.4232804232804, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI4557231, Length=374, Percent_Identity=29.9465240641711, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI187960098, Length=374, Percent_Identity=29.9465240641711, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI4557233, Length=376, Percent_Identity=27.1276595744681, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI4501857, Length=367, Percent_Identity=25.8855585831063, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=25.0666666666667, Blast_Score=113, Evalue=5e-25,
Organism=Homo sapiens, GI226958414, Length=331, Percent_Identity=26.2839879154079, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI7656849, Length=370, Percent_Identity=23.2432432432432, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI76496475, Length=384, Percent_Identity=26.3020833333333, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4557235, Length=378, Percent_Identity=26.4550264550265, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI21361497, Length=375, Percent_Identity=25.0666666666667, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4503943, Length=370, Percent_Identity=26.7567567567568, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI7669494, Length=373, Percent_Identity=26.5415549597855, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87081958, Length=375, Percent_Identity=26.6666666666667, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1786223, Length=372, Percent_Identity=23.3870967741935, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=369, Percent_Identity=31.1653116531165, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=29.7587131367292, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=31.4666666666667, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17534899, Length=374, Percent_Identity=31.5508021390374, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17570075, Length=372, Percent_Identity=28.7634408602151, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71990804, Length=311, Percent_Identity=30.8681672025724, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17538396, Length=371, Percent_Identity=25.3369272237197, Blast_Score=106, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71982178, Length=281, Percent_Identity=29.1814946619217, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17533517, Length=372, Percent_Identity=24.4623655913978, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=243, Percent_Identity=29.2181069958848, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=362, Percent_Identity=25.6906077348066, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=373, Percent_Identity=25.201072386059, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17531909, Length=235, Percent_Identity=28.5106382978723, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=25.3926701570681, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17505929, Length=408, Percent_Identity=23.5294117647059, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24666513, Length=374, Percent_Identity=28.8770053475936, Blast_Score=149, Evalue=6e-36,
Organism=Drosophila melanogaster, GI24660351, Length=380, Percent_Identity=31.3157894736842, Blast_Score=139, Evalue=3e-33,
Organism=Drosophila melanogaster, GI21356377, Length=381, Percent_Identity=28.3464566929134, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24646207, Length=371, Percent_Identity=30.188679245283, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281363737, Length=390, Percent_Identity=25.3846153846154, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21355753, Length=310, Percent_Identity=26.1290322580645, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19920834, Length=373, Percent_Identity=24.3967828418231, Blast_Score=76, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 50578; Mature: 50447

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRSKRADSTPGLNNIKRDAIGTVMGVLTKFTGSDLAEKYGLSKKVDRVAYQSTKTGMR
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHH
TLGAVNRQFKKIKGSGKPVRLANQTTDENNQPVPTEAPAPGKAPFDLTPTEDQEMIVAAV
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
REFAEERLRPTGHDQNEASEPAEGLLEAAAELGVALINLPEEYEGIASASGATTNALIAE
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCEEEECCCHHHHHHHCCCCCCHHHHHHH
ALAFGDMGQAVAILAPAGVANVITNYGDDSQQKTYLPEFAGESVPASAVVVSESRPLFDP
HHHHCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCCCC
FTLQTTAVREGDDIVINGVKTMVPNAGKAELFVIAVNLDGENTFVIVESDTEGLVVEADP
CEEEEEEECCCCCEEEECHHHHCCCCCCCEEEEEEEEECCCEEEEEEECCCCCEEEECCC
SMGLRGAALGRLLLKDVRVPASQLLGGKDLAADERKENYAEIIRRSRLGWAALAAGTGEA
CCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHEEECCCHHH
ILEYTKKYVNEREAFGEPISHRQAVAFMVANLRIELDGLRLILLRGVSRLDQGLSFNREA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHCCCCCHHH
GLARRYASDKGMVMGLDGVQLLGGHGFTKEHPVERWYRDMRAIGIAEGVVVV
HHHHHHCCCCCEEEECCCHHEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEC
>Mature Secondary Structure 
SDRSKRADSTPGLNNIKRDAIGTVMGVLTKFTGSDLAEKYGLSKKVDRVAYQSTKTGMR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHH
TLGAVNRQFKKIKGSGKPVRLANQTTDENNQPVPTEAPAPGKAPFDLTPTEDQEMIVAAV
HHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
REFAEERLRPTGHDQNEASEPAEGLLEAAAELGVALINLPEEYEGIASASGATTNALIAE
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCEEEECCCHHHHHHHCCCCCCHHHHHHH
ALAFGDMGQAVAILAPAGVANVITNYGDDSQQKTYLPEFAGESVPASAVVVSESRPLFDP
HHHHCCCCCEEEEEECCCHHHHHHCCCCCCCCCCCCHHHCCCCCCCCEEEEECCCCCCCC
FTLQTTAVREGDDIVINGVKTMVPNAGKAELFVIAVNLDGENTFVIVESDTEGLVVEADP
CEEEEEEECCCCCEEEECHHHHCCCCCCCEEEEEEEEECCCEEEEEEECCCCCEEEECCC
SMGLRGAALGRLLLKDVRVPASQLLGGKDLAADERKENYAEIIRRSRLGWAALAAGTGEA
CCCCHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHEEECCCHHH
ILEYTKKYVNEREAFGEPISHRQAVAFMVANLRIELDGLRLILLRGVSRLDQGLSFNREA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHCCCCCHHH
GLARRYASDKGMVMGLDGVQLLGGHGFTKEHPVERWYRDMRAIGIAEGVVVV
HHHHHHCCCCCEEEECCCHHEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]