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The map label for this gene is pabA [H]

Identifier: 68535098

GI number: 68535098

Start: 40841

End: 41569

Strand: Direct

Name: pabA [H]

Synonym: jk0036

Alternate gene names: 68535098

Gene position: 40841-41569 (Clockwise)

Preceding gene: 68535096

Following gene: 68535107

Centisome position: 1.66

GC content: 62.28

Gene sequence:

>729_bases
ATGCGCATTCTCGTGATCGACAACTACGACAGCTTCGTTTACAACCTCGTGCAATACATCGGGCAGCTGGGCTTCAGCGG
GGACGACTGTGTGGTGTTGCGCAATGACGCCCCCGAGCTCACAGGTGCCGGCAACCCAGACGGAGCTGACACGGATGCGC
TGGCTAACATGCTGCAGGGCTTCGACGCGATCCTGCTATCCCCCGGGCCCGGCGAACCAAGCGCGGCCGGCTGCATGCTG
GACGTGTTGAAAATCGCGGTTGAAAAGCAGATTCCGCTGTTCGGAGTGTGCCTGGGGCACCAGGCGATCGGCATGCACTT
CGGCGCGAAGGTCGTTCGGGCAGACGAACTCTTCCACGGCAAAACTTCGCCCGTGACCCACGACGGTACTGGCGTGCTGG
CCGGGGTGCCGAGCCCGTTCCGGGTGACGCGCTACCACTCGCTCACCGTTGATCCCGACACTGTACCGGAGGAACTGAAG
GTCACAGCGACTTCCGATTCCGGCATGATTATGGCGATGCGCCACCAGACGCTGCCGGTCCACTCCGTACAGTTTCACCC
CGAGTCCGTGATGACACAGTACGGCCACCTGATGCTGGCGAACTGGCTGAACGAAGCCGGGCGGTTGAACGGCACGGGCG
AGGTAGTTCCAGCCGAGCTAGTGAATCGCCTAGTGCAGGAGCAGCTAGAGGTCACCGGCGCCATCAGCGCCGAAGCCTCG
ATGCTTTAG

Upstream 100 bases:

>100_bases
CCTACGAGGTACCGAGCGCCCATGGGCAAAATACGTACCAAACGATAGTACCAGCACACCACGGCAAAACTATGCATGCT
GCCGCGCTAGACTCTTTGCT

Downstream 100 bases:

>100_bases
GGTCCGCTGAGAGGCGCTGCTGCTATTAGGGCAGCAGGTTGAAGACGTACACCGTCACGGTGATGTCCTCGTCCCGCTTA
ATCACCTGACCACTATGGAT

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Anthranilate synthase component II; Glutamine amido-transferase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MRILVIDNYDSFVYNLVQYIGQLGFSGDDCVVLRNDAPELTGAGNPDGADTDALANMLQGFDAILLSPGPGEPSAAGCML
DVLKIAVEKQIPLFGVCLGHQAIGMHFGAKVVRADELFHGKTSPVTHDGTGVLAGVPSPFRVTRYHSLTVDPDTVPEELK
VTATSDSGMIMAMRHQTLPVHSVQFHPESVMTQYGHLMLANWLNEAGRLNGTGEVVPAELVNRLVQEQLEVTGAISAEAS
ML

Sequences:

>Translated_242_residues
MRILVIDNYDSFVYNLVQYIGQLGFSGDDCVVLRNDAPELTGAGNPDGADTDALANMLQGFDAILLSPGPGEPSAAGCML
DVLKIAVEKQIPLFGVCLGHQAIGMHFGAKVVRADELFHGKTSPVTHDGTGVLAGVPSPFRVTRYHSLTVDPDTVPEELK
VTATSDSGMIMAMRHQTLPVHSVQFHPESVMTQYGHLMLANWLNEAGRLNGTGEVVPAELVNRLVQEQLEVTGAISAEAS
ML
>Mature_242_residues
MRILVIDNYDSFVYNLVQYIGQLGFSGDDCVVLRNDAPELTGAGNPDGADTDALANMLQGFDAILLSPGPGEPSAAGCML
DVLKIAVEKQIPLFGVCLGHQAIGMHFGAKVVRADELFHGKTSPVTHDGTGVLAGVPSPFRVTRYHSLTVDPDTVPEELK
VTATSDSGMIMAMRHQTLPVHSVQFHPESVMTQYGHLMLANWLNEAGRLNGTGEVVPAELVNRLVQEQLEVTGAISAEAS
ML

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=174, Percent_Identity=29.3103448275862, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1789760, Length=203, Percent_Identity=48.7684729064039, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1787517, Length=201, Percent_Identity=41.2935323383085, Blast_Score=137, Evalue=5e-34,
Organism=Escherichia coli, GI1786215, Length=129, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI193204318, Length=130, Percent_Identity=33.8461538461538, Blast_Score=81, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322638, Length=216, Percent_Identity=43.0555555555556, Blast_Score=167, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=215, Percent_Identity=31.6279069767442, Blast_Score=93, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6322331, Length=135, Percent_Identity=34.0740740740741, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6324878, Length=139, Percent_Identity=30.9352517985612, Blast_Score=63, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45555749, Length=134, Percent_Identity=33.5820895522388, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24642586, Length=134, Percent_Identity=33.5820895522388, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 25865; Mature: 25865

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVIDNYDSFVYNLVQYIGQLGFSGDDCVVLRNDAPELTGAGNPDGADTDALANMLQG
CEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCC
FDAILLSPGPGEPSAAGCMLDVLKIAVEKQIPLFGVCLGHQAIGMHFGAKVVRADELFHG
CCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCHHEEEHHHHHCC
KTSPVTHDGTGVLAGVPSPFRVTRYHSLTVDPDTVPEELKVTATSDSGMIMAMRHQTLPV
CCCCCCCCCCEEEECCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCC
HSVQFHPESVMTQYGHLMLANWLNEAGRLNGTGEVVPAELVNRLVQEQLEVTGAISAEAS
EEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
ML
CC
>Mature Secondary Structure
MRILVIDNYDSFVYNLVQYIGQLGFSGDDCVVLRNDAPELTGAGNPDGADTDALANMLQG
CEEEEEECCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHCC
FDAILLSPGPGEPSAAGCMLDVLKIAVEKQIPLFGVCLGHQAIGMHFGAKVVRADELFHG
CCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCHHEEEHHHHHCC
KTSPVTHDGTGVLAGVPSPFRVTRYHSLTVDPDTVPEELKVTATSDSGMIMAMRHQTLPV
CCCCCCCCCCEEEECCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCEEEEEECCCCCC
HSVQFHPESVMTQYGHLMLANWLNEAGRLNGTGEVVPAELVNRLVQEQLEVTGAISAEAS
EEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
ML
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]