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The map label for this gene is gluP [H]

Identifier: 68535096

GI number: 68535096

Start: 39677

End: 40402

Strand: Direct

Name: gluP [H]

Synonym: jk0034

Alternate gene names: 68535096

Gene position: 39677-40402 (Clockwise)

Preceding gene: 68535095

Following gene: 68535098

Centisome position: 1.61

GC content: 60.61

Gene sequence:

>726_bases
TTGCCGTGGCTGGACACGCAAGCCCGCCGGAATAGCCGGCGGTATTCCGTCACCAACGTATTCATCGCAGCCTGCTGCCT
TGTGTACGTGGTGACGGTTTTTCAATCCGGCAGCATTGCCAACCCCCTCGGCGGCCAATCCATGTTCGGCCTCAGCTCGA
ACAACCTGGGGCGGGAGATGCTCTTCAACGCCGCCAACGTCACCCTATTCGGTGAATGGTGGCGCATCCTCACCGCCGCA
TTCGTTCATTTGGACCCCGCCCACCTGGGCTTCAACATGTTGCTGATCTTCCTGATCGGCCGCGATGTCGAACGCTTTTA
CGGGCCAGTAGTGATGCTCAGCCTCATCGTCGCCAGTGCCGCTGGCGGTGCGCTGGCCTGCATGTACTTCCAGCCGAATG
TGCCCGTTGGCGGTGCCTCCACCGTTGGCTACGGGCTATTCGCCATGCTCATTTCTCTGTCGCGGATACGGCAGCGTGAT
CTCCGCGGGCCCATCATCCTGCTGCTGGTGAACCTTGGGTACTCCCTCATGTACTCCAATGTTTCGCTATGGGGACACAT
AGGTGGGCTCGCCGGAGGAGCCGTCATCGCATTCATCACCAGTACCGTTGGCGAGCAAGGCAATGGGGGCGTGGGGGCGT
CAATAAGCAAAAAGACCGCCGCTGCACTAGCCGCGACGGTCATCCTGGCCTTCACCATATGGACCGGCCTGGGGTGGCAC
TACTAG

Upstream 100 bases:

>100_bases
AAGGTCGTCGCGAAGATCTCTCGCGTCGCAACCGACCGCATGGACCGCCCGAACGACGACGTCGTTATCGAGTCTGTCGA
GATCCAGGAGTAAAAACTCC

Downstream 100 bases:

>100_bases
AGCAGTGCCGGGAAGTGACGTGGGTGCTACTTCCACCCCATGGTCATCAGCAGACCCACGATCAGAAGGGCGAAGCCAAT
CAGGTAGTTCCATGCGTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MPWLDTQARRNSRRYSVTNVFIAACCLVYVVTVFQSGSIANPLGGQSMFGLSSNNLGREMLFNAANVTLFGEWWRILTAA
FVHLDPAHLGFNMLLIFLIGRDVERFYGPVVMLSLIVASAAGGALACMYFQPNVPVGGASTVGYGLFAMLISLSRIRQRD
LRGPIILLLVNLGYSLMYSNVSLWGHIGGLAGGAVIAFITSTVGEQGNGGVGASISKKTAAALAATVILAFTIWTGLGWH
Y

Sequences:

>Translated_241_residues
MPWLDTQARRNSRRYSVTNVFIAACCLVYVVTVFQSGSIANPLGGQSMFGLSSNNLGREMLFNAANVTLFGEWWRILTAA
FVHLDPAHLGFNMLLIFLIGRDVERFYGPVVMLSLIVASAAGGALACMYFQPNVPVGGASTVGYGLFAMLISLSRIRQRD
LRGPIILLLVNLGYSLMYSNVSLWGHIGGLAGGAVIAFITSTVGEQGNGGVGASISKKTAAALAATVILAFTIWTGLGWH
Y
>Mature_240_residues
PWLDTQARRNSRRYSVTNVFIAACCLVYVVTVFQSGSIANPLGGQSMFGLSSNNLGREMLFNAANVTLFGEWWRILTAAF
VHLDPAHLGFNMLLIFLIGRDVERFYGPVVMLSLIVASAAGGALACMYFQPNVPVGGASTVGYGLFAMLISLSRIRQRDL
RGPIILLLVNLGYSLMYSNVSLWGHIGGLAGGAVIAFITSTVGEQGNGGVGASISKKTAAALAATVILAFTIWTGLGWHY

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis. Important for normal cell division and sporulation. May act as a glucose exporter [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 TPR repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002610
- InterPro:   IPR022764
- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF01694 Rhomboid; PF00515 TPR_1 [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 25757; Mature: 25626

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWLDTQARRNSRRYSVTNVFIAACCLVYVVTVFQSGSIANPLGGQSMFGLSSNNLGREM
CCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCHHH
LFNAANVTLFGEWWRILTAAFVHLDPAHLGFNMLLIFLIGRDVERFYGPVVMLSLIVASA
HHHHCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
AGGALACMYFQPNVPVGGASTVGYGLFAMLISLSRIRQRDLRGPIILLLVNLGYSLMYSN
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHCC
VSLWGHIGGLAGGAVIAFITSTVGEQGNGGVGASISKKTAAALAATVILAFTIWTGLGWH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
Y
C
>Mature Secondary Structure 
PWLDTQARRNSRRYSVTNVFIAACCLVYVVTVFQSGSIANPLGGQSMFGLSSNNLGREM
CCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCHHH
LFNAANVTLFGEWWRILTAAFVHLDPAHLGFNMLLIFLIGRDVERFYGPVVMLSLIVASA
HHHHCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
AGGALACMYFQPNVPVGGASTVGYGLFAMLISLSRIRQRDLRGPIILLLVNLGYSLMYSN
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCHHHHHCC
VSLWGHIGGLAGGAVIAFITSTVGEQGNGGVGASISKKTAAALAATVILAFTIWTGLGWH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]