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The map label for this gene is lacF [H]

Identifier: 66768234

GI number: 66768234

Start: 2311478

End: 2312362

Strand: Direct

Name: lacF [H]

Synonym: XC_1913

Alternate gene names: 66768234

Gene position: 2311478-2312362 (Clockwise)

Preceding gene: 66768233

Following gene: 66768235

Centisome position: 44.89

GC content: 62.82

Gene sequence:

>885_bases
ATGATGAAGCGCAACTCCGTGGCCGGCTGGGTCTTCGCCGCGCCGTCGATCCTGGTGCTGGGCATGTTCTTCGGCGTGCC
GGTGTTCGCCGCGCTGGTGCTCAGCGTCACCGACTTCGACCTGTACGCACTGGCCGACAGCAGCCATCTGCGCTTCGTCG
GCCTGGGCAACTACATCGAGCTGCTGCAGACGCCGCTGTTCTGGAAGTCGCTGTGGAATACCACCTACTTCGTGCTGCTG
GGCGTACCGATGTCCATCGCGGTGTCGCTGGGCGCGGCGCTGCTGCTCAATGCCAAGGCTTCGCGGTTCAAGGCCTTGTT
CCGCACCGCGTTGTTCGCGCCGGTGGTCACCACGCTGGTGGCAGTCGCGGTGATCTGGCGCTACCTGTTCCACATCAAGT
ACGGCCTGGTGAATTTCGGCCTGAGCCACCTGGGCATCGCCCCGATCGACTGGCTGGGTGATCCGCGCTGGGCAATGCCG
ACCATCATGCTGTTCGCGGTGTGGAAGAACTTCGGCTACAACATGGTGATCTTCCTGGCCGGCCTGCAGGCGATCCCGCA
AGACCTCTACGAGGCGGCGCGCATCGACGGTGCCTCGCGCTGGAAGCAGTTCCTGCACATCACCTTGCCGATGCTCGGCC
CGGTGCTGATGGTGGTCGGTGTGATCACCATCTCCGGTTATTTCCAGCTGTTCGCCGAACCCTATGTGATGACCCGCGGC
GACCCACTGCAAAGCACCGTGAGCGTGCTGTATTTCATGTTCGAGGAAGGCTTCAAGTGGTGGAACCTCGGCCGCGCGTC
GGCGGTGGCGTTCCTGCTGTTCCTGATCATCCTGACCGTGACCACCGTGATGCTGCGCTTCGGGCGCAAGAAGGACCTGA
TATGA

Upstream 100 bases:

>100_bases
GCTGGATCTACGAACAGGAAGGCGGGCATGTCGGCCCGGCGGCCGCACCGGCCACGCCGATGCCTGCGCCGGCGAATGCA
GCGGCTGAAGGAGCTGCCCG

Downstream 100 bases:

>100_bases
GTCGTGATGTGGGCGAATCGCGCTGGAATGGCCTGCTGATCAATGGCGGGTTGTTGCTGCTGGCGCTGGTCAGCCTGGCG
CCGCTGTTGTGGATGCTGTC

Product: ABC transporter sugar permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MMKRNSVAGWVFAAPSILVLGMFFGVPVFAALVLSVTDFDLYALADSSHLRFVGLGNYIELLQTPLFWKSLWNTTYFVLL
GVPMSIAVSLGAALLLNAKASRFKALFRTALFAPVVTTLVAVAVIWRYLFHIKYGLVNFGLSHLGIAPIDWLGDPRWAMP
TIMLFAVWKNFGYNMVIFLAGLQAIPQDLYEAARIDGASRWKQFLHITLPMLGPVLMVVGVITISGYFQLFAEPYVMTRG
DPLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLIILTVTTVMLRFGRKKDLI

Sequences:

>Translated_294_residues
MMKRNSVAGWVFAAPSILVLGMFFGVPVFAALVLSVTDFDLYALADSSHLRFVGLGNYIELLQTPLFWKSLWNTTYFVLL
GVPMSIAVSLGAALLLNAKASRFKALFRTALFAPVVTTLVAVAVIWRYLFHIKYGLVNFGLSHLGIAPIDWLGDPRWAMP
TIMLFAVWKNFGYNMVIFLAGLQAIPQDLYEAARIDGASRWKQFLHITLPMLGPVLMVVGVITISGYFQLFAEPYVMTRG
DPLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLIILTVTTVMLRFGRKKDLI
>Mature_294_residues
MMKRNSVAGWVFAAPSILVLGMFFGVPVFAALVLSVTDFDLYALADSSHLRFVGLGNYIELLQTPLFWKSLWNTTYFVLL
GVPMSIAVSLGAALLLNAKASRFKALFRTALFAPVVTTLVAVAVIWRYLFHIKYGLVNFGLSHLGIAPIDWLGDPRWAMP
TIMLFAVWKNFGYNMVIFLAGLQAIPQDLYEAARIDGASRWKQFLHITLPMLGPVLMVVGVITISGYFQLFAEPYVMTRG
DPLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLIILTVTTVMLRFGRKKDLI

Specific function: Part of the binding-protein-dependent transport system for lactose. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1175

COG function: function code G; ABC-type sugar transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787570, Length=233, Percent_Identity=34.7639484978541, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1789861, Length=287, Percent_Identity=29.9651567944251, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1790465, Length=244, Percent_Identity=31.5573770491803, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32956; Mature: 32956

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKRNSVAGWVFAAPSILVLGMFFGVPVFAALVLSVTDFDLYALADSSHLRFVGLGNYIE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHH
LLQTPLFWKSLWNTTYFVLLGVPMSIAVSLGAALLLNAKASRFKALFRTALFAPVVTTLV
HHHCHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAVIWRYLFHIKYGLVNFGLSHLGIAPIDWLGDPRWAMPTIMLFAVWKNFGYNMVIFLA
HHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
GLQAIPQDLYEAARIDGASRWKQFLHITLPMLGPVLMVVGVITISGYFQLFAEPYVMTRG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
DPLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLIILTVTTVMLRFGRKKDLI
CCHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMKRNSVAGWVFAAPSILVLGMFFGVPVFAALVLSVTDFDLYALADSSHLRFVGLGNYIE
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCHHHH
LLQTPLFWKSLWNTTYFVLLGVPMSIAVSLGAALLLNAKASRFKALFRTALFAPVVTTLV
HHHCHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVAVIWRYLFHIKYGLVNFGLSHLGIAPIDWLGDPRWAMPTIMLFAVWKNFGYNMVIFLA
HHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHH
GLQAIPQDLYEAARIDGASRWKQFLHITLPMLGPVLMVVGVITISGYFQLFAEPYVMTRG
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
DPLQSTVSVLYFMFEEGFKWWNLGRASAVAFLLFLIILTVTTVMLRFGRKKDLI
CCHHHHHHHHHHHHHHCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1630315 [H]