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The map label for this gene is virB11 [H]

Identifier: 66767959

GI number: 66767959

Start: 1961592

End: 1962650

Strand: Direct

Name: virB11 [H]

Synonym: XC_1635

Alternate gene names: 66767959

Gene position: 1961592-1962650 (Clockwise)

Preceding gene: 66767958

Following gene: 66767960

Centisome position: 38.1

GC content: 55.24

Gene sequence:

>1059_bases
GTGAGCGCGACCACGGCCATGACGATCGACGATTCGCCGACAGCGCGGATCTCGAATGATTTCCTGGATTATCAGTACTC
CGTACTGGGAATCCTGGATTATCTGAATTCTCCCGAAGTCACGGAAATTTGTATCAATCGTCCTGGCGAGTTGTATTTGG
AAACGATCAACGGCTGGCAGCGCATGGAGGTACCGTCGCTGACCTTTGATCGCGCCCGACAGTTCTGCACGGCAGTCGTC
AACGAGAGCAATACTGGTCAGCGCATTACCGATGCCGATCCGGTGGTCTCATTAACGTTTCCCACTGGCCAACGCGCACA
GTTCGTAATTCCGCCCGCGTGCGATGCGGGGAAGGTCTCGATCACGATTCGCTTGCCGTCCAAACATACCAAGACGCTCG
AGCAGTACACCAGCGACGGGTTCTTCGACGAGGTGCTTGAGCAAGCTGCGGATGTCAGCGAACAAGACCGCGAACTGCTT
GAGTTGCGTCGTAGCAAGCAGTACTCCGAATTCTTCAAGAAGTCGGTACTTTACAAGAAGAATGTAGTGGTGGCCGGTGC
GACTGGTAGTGGCAAGACTACTTTCATGAAGGCTCTTGTCAACCACATTCCGAACGAAGAACGCCTGGTTACCATCGAGG
ACGCCCGCGAGCTATTCATCAGCCAGCCGAATTCGGTGCATCTGTTGTACTCGAAAGGGGGGCAGAGTGCGAGTAATGTG
ACCGCTAAGAGTTGCATGGAGGCCTGCCTGCGCATGAAGCCTGATCGGATCATCCTTGCTGAGTTGCGTGGTGACGAATC
GTTCTATTTCATCCGCAATTGTGCATCCGGCCATCCTGGTTCAATCACCAGCTGCCACGCAGGCAGCGTGGAACAGACCT
GGGACCAGCTCGCGCTCATGGTGAAGGCCTCCAATGAAGGTTCCGGGCTGGAGTTCGAGGTTATCAAGCGGCTGCTGCGC
ATGACCATCGATATCGTGGTTCACATCAAGGCGCATGCTGGGCGCCGCTTTATTACTGGGATCGACTTCGATCCGGCAAG
AACACTGCGTGGCGGCTGA

Upstream 100 bases:

>100_bases
AAAAGTCAGGTCGTCGCCCGGCAACGCTGACGATCAATCAGGGAACAGTCCTGAACGTTTACGTTGCAAAGGATGTCGAT
TTCTCAGCGGTGCTGCCTAA

Downstream 100 bases:

>100_bases
TCGGCCGCCAATGATTGACGTCGATCCAGTTTCGAGGAAACCGTTATGTTGCCTGGCATGGAATTGATGGGATGTACTGG
ACTTGCCGTACCCGGCGAGG

Product: VirB11 protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSATTAMTIDDSPTARISNDFLDYQYSVLGILDYLNSPEVTEICINRPGELYLETINGWQRMEVPSLTFDRARQFCTAVV
NESNTGQRITDADPVVSLTFPTGQRAQFVIPPACDAGKVSITIRLPSKHTKTLEQYTSDGFFDEVLEQAADVSEQDRELL
ELRRSKQYSEFFKKSVLYKKNVVVAGATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNSVHLLYSKGGQSASNV
TAKSCMEACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALMVKASNEGSGLEFEVIKRLLR
MTIDIVVHIKAHAGRRFITGIDFDPARTLRGG

Sequences:

>Translated_352_residues
MSATTAMTIDDSPTARISNDFLDYQYSVLGILDYLNSPEVTEICINRPGELYLETINGWQRMEVPSLTFDRARQFCTAVV
NESNTGQRITDADPVVSLTFPTGQRAQFVIPPACDAGKVSITIRLPSKHTKTLEQYTSDGFFDEVLEQAADVSEQDRELL
ELRRSKQYSEFFKKSVLYKKNVVVAGATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNSVHLLYSKGGQSASNV
TAKSCMEACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALMVKASNEGSGLEFEVIKRLLR
MTIDIVVHIKAHAGRRFITGIDFDPARTLRGG
>Mature_351_residues
SATTAMTIDDSPTARISNDFLDYQYSVLGILDYLNSPEVTEICINRPGELYLETINGWQRMEVPSLTFDRARQFCTAVVN
ESNTGQRITDADPVVSLTFPTGQRAQFVIPPACDAGKVSITIRLPSKHTKTLEQYTSDGFFDEVLEQAADVSEQDRELLE
LRRSKQYSEFFKKSVLYKKNVVVAGATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNSVHLLYSKGGQSASNVT
AKSCMEACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALMVKASNEGSGLEFEVIKRLLRM
TIDIVVHIKAHAGRRFITGIDFDPARTLRGG

Specific function: The virB operon is essential for intracellular survival and is not involved in the invasion process. Constitutes a major determinant of virulence in mice. Virb11 is essential for pathogenesis in mice but is not required for intracellular survival [H]

COG id: COG0630

COG function: function code NU; Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014155
- InterPro:   IPR002078
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 39147; Mature: 39016

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATTAMTIDDSPTARISNDFLDYQYSVLGILDYLNSPEVTEICINRPGELYLETINGWQ
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCCCE
RMEVPSLTFDRARQFCTAVVNESNTGQRITDADPVVSLTFPTGQRAQFVIPPACDAGKVS
ECCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCCCCCEEEECCCCCCCEEE
ITIRLPSKHTKTLEQYTSDGFFDEVLEQAADVSEQDRELLELRRSKQYSEFFKKSVLYKK
EEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEC
NVVVAGATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNSVHLLYSKGGQSASNV
CEEEEECCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCHHH
TAKSCMEACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALM
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHEEEE
VKASNEGSGLEFEVIKRLLRMTIDIVVHIKAHAGRRFITGIDFDPARTLRGG
EEECCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCEEEECCCCCCCHHCCCC
>Mature Secondary Structure 
SATTAMTIDDSPTARISNDFLDYQYSVLGILDYLNSPEVTEICINRPGELYLETINGWQ
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCEEEEECCCCE
RMEVPSLTFDRARQFCTAVVNESNTGQRITDADPVVSLTFPTGQRAQFVIPPACDAGKVS
ECCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCCCCCEEEECCCCCCCEEE
ITIRLPSKHTKTLEQYTSDGFFDEVLEQAADVSEQDRELLELRRSKQYSEFFKKSVLYKK
EEEECCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHEEC
NVVVAGATGSGKTTFMKALVNHIPNEERLVTIEDARELFISQPNSVHLLYSKGGQSASNV
CEEEEECCCCCHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCEEEEEECCCCCCHHH
TAKSCMEACLRMKPDRIILAELRGDESFYFIRNCASGHPGSITSCHAGSVEQTWDQLALM
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHEEEE
VKASNEGSGLEFEVIKRLLRMTIDIVVHIKAHAGRRFITGIDFDPARTLRGG
EEECCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCEEEECCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10940027 [H]