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The map label for this gene is udg [H]

Identifier: 66048329

GI number: 66048329

Start: 6056765

End: 6058114

Strand: Direct

Name: udg [H]

Synonym: Psyr_5105

Alternate gene names: 66048329

Gene position: 6056765-6058114 (Clockwise)

Preceding gene: 66048328

Following gene: 66048330

Centisome position: 99.39

GC content: 59.33

Gene sequence:

>1350_bases
ATGAGGCGGAAGGAGCGGCACTTGAAAGTGACAGTGTTCGGAACCGGTTATGTGGGGCTTACTCTTGCCGCCTGTCTGGC
TGAAGTAGGCCATACCGTCTGTTGCATGGATGTCGACAGCAAGCGCATTGATGCGCTTCGCGAAGGCATATGTCCGATAT
TCGAACCCGGTCTTGGCGAACTTCTGCGCAACGGCCTGGACTGCAAAAGACTGAGTTTCACGACCGATGAGGTACACGCC
AGTCGCTTTGCAGAGTTGGTCTTCATCGCCGTCGGTACGCCAGCGCAAGCCGACGGCAAGGCGGACCTGAGCCAGGTGCT
TGCCGTACTGCGCTGCGTGATCAGACACGCCGAAAGTGCCCCGATCATTGTCAACAAGTCGACCTCGCCAGTGGGCACCG
TTGACCGCCTGCTCGCTGAGATAGCTGCCAGTGCGCGATGCGATGACGGCTTTGAAGTGATCAGCAACCCCGAGTTTTTC
AAGGAAGGCTGCGCAGTCAGTGATTGCCTGCGTCCGGATCGCATTATTGTCGGCGGGGCCAGTCCGCGAGCGCTGGAGCA
GATGCGCGAGTTGTATCAGCCCTTCAGTCGCAACCGCGAGAAGTTTGTGGTCATGGATGCGCGCAGCGCAGAGCTGTCCA
AATACGCTGCCAACTGCCTGCTGGCGACCAAGATTTCGTTCATCAACGAGATCGCCAACCTGGCTGAACAGGTGGGTGCT
GACATAGAACAGGTCCGGCTTGGCATCGGCTCCGACCCTCGTATCGGTTATGACTTCATTTACCCGGGCTGCGGCTTCGG
TGGCTCATGCTTTCCCAAGGACTTGCAGGCGCTGATCGGCACGGCCAGCGAGCACGGCGTGGAGACGGCGTTGCTCAACG
CCGTGGAACAGGTCAATCGCCGCCAGAAGCACCGCCTGTTCGAAAATATCCACACGCATTATCACGGTGATCTGAGGGGC
AAGGTCTTCGCTGTCTGGGGACTGGCCTTCAAGCCCAATACCGATGACATTCGCGAAGCAACCAGCCATACCCTGCTCAA
AGCACTCTGGGCAGCCGGTGCCAGGGTTCAAGCGCACGACCCTCAAGCAATAGAAGCGGTCAGGCATCATTACGGCGAGC
GAAACGACCTGCAACTGGTGCAGTGCAAGCAAGATGCACTGGAAGGCGCAGACGCTCTGGTGGTGGTGACCGAATGGCAG
GACTACCGGGTGCTGGATCTGGACGCGCTCGGCGAAACGCTCGGTGATCGCGTGGTGTTCGATGGCCGCAACCTGTTCGA
CCCGTTGCAGCTGCGTGAGGCGGGCTTTACCTACTACGGCATTGGTCGTGGCCAGGCGACGCCGGCATGA

Upstream 100 bases:

>100_bases
TCGTGTCATCGTTCCTTAACACCTTTATGACATTTATTTTGCGCTGGTTATTTCAGGCTGCCGAGGCGCCTGAGAACAAA
CCGGCTCATCCATTCATGTC

Downstream 100 bases:

>100_bases
CGGTACTGGTGACAGGTGCTGCAGGGTTCATCGGGTTTCATGTCGCCAAGCGTCTGTGCGAGCTCGGCGTAGAGGTCGTC
GGCATCGACAACCTCAACGA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MRRKERHLKVTVFGTGYVGLTLAACLAEVGHTVCCMDVDSKRIDALREGICPIFEPGLGELLRNGLDCKRLSFTTDEVHA
SRFAELVFIAVGTPAQADGKADLSQVLAVLRCVIRHAESAPIIVNKSTSPVGTVDRLLAEIAASARCDDGFEVISNPEFF
KEGCAVSDCLRPDRIIVGGASPRALEQMRELYQPFSRNREKFVVMDARSAELSKYAANCLLATKISFINEIANLAEQVGA
DIEQVRLGIGSDPRIGYDFIYPGCGFGGSCFPKDLQALIGTASEHGVETALLNAVEQVNRRQKHRLFENIHTHYHGDLRG
KVFAVWGLAFKPNTDDIREATSHTLLKALWAAGARVQAHDPQAIEAVRHHYGERNDLQLVQCKQDALEGADALVVVTEWQ
DYRVLDLDALGETLGDRVVFDGRNLFDPLQLREAGFTYYGIGRGQATPA

Sequences:

>Translated_449_residues
MRRKERHLKVTVFGTGYVGLTLAACLAEVGHTVCCMDVDSKRIDALREGICPIFEPGLGELLRNGLDCKRLSFTTDEVHA
SRFAELVFIAVGTPAQADGKADLSQVLAVLRCVIRHAESAPIIVNKSTSPVGTVDRLLAEIAASARCDDGFEVISNPEFF
KEGCAVSDCLRPDRIIVGGASPRALEQMRELYQPFSRNREKFVVMDARSAELSKYAANCLLATKISFINEIANLAEQVGA
DIEQVRLGIGSDPRIGYDFIYPGCGFGGSCFPKDLQALIGTASEHGVETALLNAVEQVNRRQKHRLFENIHTHYHGDLRG
KVFAVWGLAFKPNTDDIREATSHTLLKALWAAGARVQAHDPQAIEAVRHHYGERNDLQLVQCKQDALEGADALVVVTEWQ
DYRVLDLDALGETLGDRVVFDGRNLFDPLQLREAGFTYYGIGRGQATPA
>Mature_449_residues
MRRKERHLKVTVFGTGYVGLTLAACLAEVGHTVCCMDVDSKRIDALREGICPIFEPGLGELLRNGLDCKRLSFTTDEVHA
SRFAELVFIAVGTPAQADGKADLSQVLAVLRCVIRHAESAPIIVNKSTSPVGTVDRLLAEIAASARCDDGFEVISNPEFF
KEGCAVSDCLRPDRIIVGGASPRALEQMRELYQPFSRNREKFVVMDARSAELSKYAANCLLATKISFINEIANLAEQVGA
DIEQVRLGIGSDPRIGYDFIYPGCGFGGSCFPKDLQALIGTASEHGVETALLNAVEQVNRRQKHRLFENIHTHYHGDLRG
KVFAVWGLAFKPNTDDIREATSHTLLKALWAAGARVQAHDPQAIEAVRHHYGERNDLQLVQCKQDALEGADALVVVTEWQ
DYRVLDLDALGETLGDRVVFDGRNLFDPLQLREAGFTYYGIGRGQATPA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=463, Percent_Identity=34.5572354211663, Blast_Score=227, Evalue=2e-59,
Organism=Homo sapiens, GI296040438, Length=362, Percent_Identity=35.0828729281768, Blast_Score=183, Evalue=4e-46,
Organism=Homo sapiens, GI296040443, Length=310, Percent_Identity=36.4516129032258, Blast_Score=165, Evalue=8e-41,
Organism=Escherichia coli, GI1788340, Length=383, Percent_Identity=30.5483028720627, Blast_Score=158, Evalue=8e-40,
Organism=Escherichia coli, GI48994968, Length=438, Percent_Identity=25.5707762557078, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17560350, Length=462, Percent_Identity=32.9004329004329, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI17136908, Length=461, Percent_Identity=32.5379609544469, Blast_Score=223, Evalue=3e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49295; Mature: 49295

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRKERHLKVTVFGTGYVGLTLAACLAEVGHTVCCMDVDSKRIDALREGICPIFEPGLGE
CCCCCCEEEEEEEECCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCCCCCCHHH
LLRNGLDCKRLSFTTDEVHASRFAELVFIAVGTPAQADGKADLSQVLAVLRCVIRHAESA
HHHCCCCCCEEECCHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PIIVNKSTSPVGTVDRLLAEIAASARCDDGFEVISNPEFFKEGCAVSDCLRPDRIIVGGA
CEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCHHHCCCCCEEEEECC
SPRALEQMRELYQPFSRNREKFVVMDARSAELSKYAANCLLATKISFINEIANLAEQVGA
CHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEQVRLGIGSDPRIGYDFIYPGCGFGGSCFPKDLQALIGTASEHGVETALLNAVEQVNR
CHHHHHHCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RQKHRLFENIHTHYHGDLRGKVFAVWGLAFKPNTDDIREATSHTLLKALWAAGARVQAHD
HHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCC
PQAIEAVRHHYGERNDLQLVQCKQDALEGADALVVVTEWQDYRVLDLDALGETLGDRVVF
CHHHHHHHHHCCCCCCCEEHEEHHHHHCCCCEEEEEEECCCCEEEEHHHHHHHHCCEEEE
DGRNLFDPLQLREAGFTYYGIGRGQATPA
CCCCCCCHHHHHHCCCEEEECCCCCCCCC
>Mature Secondary Structure
MRRKERHLKVTVFGTGYVGLTLAACLAEVGHTVCCMDVDSKRIDALREGICPIFEPGLGE
CCCCCCEEEEEEEECCHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCCCCCCCCHHH
LLRNGLDCKRLSFTTDEVHASRFAELVFIAVGTPAQADGKADLSQVLAVLRCVIRHAESA
HHHCCCCCCEEECCHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCC
PIIVNKSTSPVGTVDRLLAEIAASARCDDGFEVISNPEFFKEGCAVSDCLRPDRIIVGGA
CEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCHHHHHCCCHHHCCCCCEEEEECC
SPRALEQMRELYQPFSRNREKFVVMDARSAELSKYAANCLLATKISFINEIANLAEQVGA
CHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIEQVRLGIGSDPRIGYDFIYPGCGFGGSCFPKDLQALIGTASEHGVETALLNAVEQVNR
CHHHHHHCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
RQKHRLFENIHTHYHGDLRGKVFAVWGLAFKPNTDDIREATSHTLLKALWAAGARVQAHD
HHHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCEEECCC
PQAIEAVRHHYGERNDLQLVQCKQDALEGADALVVVTEWQDYRVLDLDALGETLGDRVVF
CHHHHHHHHHCCCCCCCEEHEEHHHHHCCCCEEEEEEECCCCEEEEHHHHHHHHCCEEEE
DGRNLFDPLQLREAGFTYYGIGRGQATPA
CCCCCCCHHHHHHCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]