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The map label for this gene is fabR [H]

Identifier: 66047677

GI number: 66047677

Start: 5316377

End: 5317009

Strand: Direct

Name: fabR [H]

Synonym: Psyr_4450

Alternate gene names: 66047677

Gene position: 5316377-5317009 (Clockwise)

Preceding gene: 66047675

Following gene: 66047678

Centisome position: 87.24

GC content: 63.82

Gene sequence:

>633_bases
ATGCTGCCCCGCGCCGAACAGAAACAACAGACCCGAAGAGCCTTGCTCGATGCTGCCCATCAACTGATGGAGAGCGGGCG
CGGCTTCGGCAGCCTGAGCCTGCGCGAAGTGGCGCGCACGGCGGGCATCGTACCGACCGGTTTCTACCGGCACTTTGAAG
ACATGGACCAGCTGGGGCTGGCGCTGGTCAGCGAGGTCGGCCAGACCTTTCGCGAGACCATCCGGCTGGTGCGCCACAAC
GAATTCGCCATGGGCGGGCTGATTCGTGCATCGGTGAAGATATTCCTCGAGCGCGTAGCGGCCAACCGCTCGCAGTTCCT
GTTTCTGGCGCGCGAACAATACGGCGGCTCCTTGAAGGTGCGCCAGGCGCTCGGAGCGCTGCGCGAAGGCATCAGCGCCG
ACCTTACGGCCGATCTGGCAAAGATGCCCAAATGGCAGCACCTGAACGCCGATGCACTGTCGATCATCGCCGACCTGGTG
GTGAAAAGCGTGTTTGCGATGCTGCCGGAACTGATCGACCCGCCCCCCGCCTCACTCGCCCCGCACCTGACCCCTCAGGC
GAAGATCACTCAGCAACTGCGCTTCATCTTCATCGGCGCACGGCACTGGCGGGGGCTGGGCAGTCATGATTGA

Upstream 100 bases:

>100_bases
CACTATTACTGGTCAAGGAGCCTGACTGAAAACCCTTTCGACGCAGGTAAAGCGCATTTGCTAAAGTGCATCCCAGCCTA
ATCCAAGAATCGTTTGAGCC

Downstream 100 bases:

>100_bases
GCGTCAGCACGCTGTACTCCGTCCTGCGGCGCTAACCGTCTCACTATTAACGTTATCTTGACCACCACACCCTGCACCAA
CTTAAAGCACGAACTTGATT

Product: regulatory protein, TetR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MLPRAEQKQQTRRALLDAAHQLMESGRGFGSLSLREVARTAGIVPTGFYRHFEDMDQLGLALVSEVGQTFRETIRLVRHN
EFAMGGLIRASVKIFLERVAANRSQFLFLAREQYGGSLKVRQALGALREGISADLTADLAKMPKWQHLNADALSIIADLV
VKSVFAMLPELIDPPPASLAPHLTPQAKITQQLRFIFIGARHWRGLGSHD

Sequences:

>Translated_210_residues
MLPRAEQKQQTRRALLDAAHQLMESGRGFGSLSLREVARTAGIVPTGFYRHFEDMDQLGLALVSEVGQTFRETIRLVRHN
EFAMGGLIRASVKIFLERVAANRSQFLFLAREQYGGSLKVRQALGALREGISADLTADLAKMPKWQHLNADALSIIADLV
VKSVFAMLPELIDPPPASLAPHLTPQAKITQQLRFIFIGARHWRGLGSHD
>Mature_210_residues
MLPRAEQKQQTRRALLDAAHQLMESGRGFGSLSLREVARTAGIVPTGFYRHFEDMDQLGLALVSEVGQTFRETIRLVRHN
EFAMGGLIRASVKIFLERVAANRSQFLFLAREQYGGSLKVRQALGALREGISADLTADLAKMPKWQHLNADALSIIADLV
VKSVFAMLPELIDPPPASLAPHLTPQAKITQQLRFIFIGARHWRGLGSHD

Specific function: Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, fabR directly influences the physical properties of the membrane bilayer [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693209, Length=203, Percent_Identity=37.9310344827586, Blast_Score=117, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR015893
- InterPro:   IPR001647 [H]

Pfam domain/function: PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 23333; Mature: 23333

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPRAEQKQQTRRALLDAAHQLMESGRGFGSLSLREVARTAGIVPTGFYRHFEDMDQLGL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ALVSEVGQTFRETIRLVRHNEFAMGGLIRASVKIFLERVAANRSQFLFLAREQYGGSLKV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEEHHHCCCCHHH
RQALGALREGISADLTADLAKMPKWQHLNADALSIIADLVVKSVFAMLPELIDPPPASLA
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PHLTPQAKITQQLRFIFIGARHWRGLGSHD
CCCCCHHHHHHHHHHHHEEHHHHCCCCCCC
>Mature Secondary Structure
MLPRAEQKQQTRRALLDAAHQLMESGRGFGSLSLREVARTAGIVPTGFYRHFEDMDQLGL
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ALVSEVGQTFRETIRLVRHNEFAMGGLIRASVKIFLERVAANRSQFLFLAREQYGGSLKV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEEHHHCCCCHHH
RQALGALREGISADLTADLAKMPKWQHLNADALSIIADLVVKSVFAMLPELIDPPPASLA
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PHLTPQAKITQQLRFIFIGARHWRGLGSHD
CCCCCHHHHHHHHHHHHEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA