Click here to switch to the map view.

The map label for this gene is mrdB [H]

Identifier: 66047591

GI number: 66047591

Start: 5217420

End: 5218565

Strand: Reverse

Name: mrdB [H]

Synonym: Psyr_4364

Alternate gene names: 66047591

Gene position: 5218565-5217420 (Counterclockwise)

Preceding gene: 66047592

Following gene: 66047590

Centisome position: 85.64

GC content: 58.81

Gene sequence:

>1146_bases
GTGAAGAGTAATTTCGACCGCATCCTGTCCAGTGAAGACGTGATGCGTCGCCGCGCCACGTTTCTGCAGCGCATTCATAT
CGATGGCCCATTGCTGATCCTGCTGCTGACGCTGGCGGCGGGCAGCCTGTTCGTGCTGTATTCGGCCAGCGGCAAGAACT
GGGACCTGCTGATCAAACAGGCCAGTTCGTTCGGCATCGGTCTGGTGGCAATGGTGGTGATCGCCCAGCTGGAGCCGCGC
TTCATGGCGCGCTGGGTGCCGGTGCTGTATGTCATCGGCGTGCTGCTGCTGGTGGTGGTGGATGTCATGGGCCACAACGC
CATGGGCGCAACGCGCTGGATCAACATTCCCGGGGTGATCCGCTTCCAGCCTTCGGAGTTTCTCAAGATCATTATGCCGG
CGACCATCGCCTGGTACCTGTCCAAGCGCACGCTGCCGCCGCATTTGAAGCACGTGGCGGTCAGTCTCGCCCTGATTGGT
GTGCCGTTCATTCTGATCGTGCGCCAGCCCGACCTGGGAACGTCACTGCTGATTCTGGCGTCGGGTGCCTTCGTGCTGTT
CATGGCCGGTTTGCGCTGGCGCTGGATTATCAGTGTACTGGCGGCGGCCATACCGGCCGCGGTGGCCATGTGGTTCTTCT
TCATGCACGACTACCAGAAGCAGCGCGTACTGACCTTTCTGGACCCCGAAAGCGATCCGCTGGGGACCGGCTGGAACATC
ATTCAGTCAAAGGCTGCGATCGGTTCGGGCGGCGTGTTCGGCAAAGGCTGGTTGCTCGGTACCCAGTCGCACCTCGACTT
TCTGCCGGAAAGCCATACCGACTTCATCATTGCAGTATTGGGTGAAGAGTTCGGCCTGGTAGGCATCTGTGCGCTGCTGA
TCATCTATATGCTGCTGATCGGCCGCGGGCTTGTGATCACTGCGCAGGCGCAGACATTATTCGGCAAACTGCTGGCCGGC
GCGTTGACCATGACGTTTTTTGTTTACGTTTTCGTCAACATCGGTATGGTCAGTGGCCTGCTGCCAGTGGTGGGGGTGCC
GTTGCCCTTCATTAGCTACGGCGGAACTTCGCTCGTGACCCTACTGTCAGCGTTTGGGGTTTTGATGTCGATCCATACAC
ATCGTAAATGGATCGCTCAAGTTTGA

Upstream 100 bases:

>100_bases
GCACCCGTCGTGCGTCAGGTCCTGGACGCCTGGCTGCTCGACGAAAACGGCCATCTCAAACCCGAGTACGCCGGTTCCCT
GAATCTGGAGGCTGCGGCCC

Downstream 100 bases:

>100_bases
TTAAGGTGAACTATTCAATGCAAGCAATGCGTAACTGGGCTCGATATGCTCCGGTGGTCGGTCTGGTGGGCATCCTTGGC
TCGGTGCAAGAGGCGCTGGC

Product: cell cycle protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MKSNFDRILSSEDVMRRRATFLQRIHIDGPLLILLLTLAAGSLFVLYSASGKNWDLLIKQASSFGIGLVAMVVIAQLEPR
FMARWVPVLYVIGVLLLVVVDVMGHNAMGATRWINIPGVIRFQPSEFLKIIMPATIAWYLSKRTLPPHLKHVAVSLALIG
VPFILIVRQPDLGTSLLILASGAFVLFMAGLRWRWIISVLAAAIPAAVAMWFFFMHDYQKQRVLTFLDPESDPLGTGWNI
IQSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLIIYMLLIGRGLVITAQAQTLFGKLLAG
ALTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVTLLSAFGVLMSIHTHRKWIAQV

Sequences:

>Translated_381_residues
MKSNFDRILSSEDVMRRRATFLQRIHIDGPLLILLLTLAAGSLFVLYSASGKNWDLLIKQASSFGIGLVAMVVIAQLEPR
FMARWVPVLYVIGVLLLVVVDVMGHNAMGATRWINIPGVIRFQPSEFLKIIMPATIAWYLSKRTLPPHLKHVAVSLALIG
VPFILIVRQPDLGTSLLILASGAFVLFMAGLRWRWIISVLAAAIPAAVAMWFFFMHDYQKQRVLTFLDPESDPLGTGWNI
IQSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLIIYMLLIGRGLVITAQAQTLFGKLLAG
ALTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVTLLSAFGVLMSIHTHRKWIAQV
>Mature_381_residues
MKSNFDRILSSEDVMRRRATFLQRIHIDGPLLILLLTLAAGSLFVLYSASGKNWDLLIKQASSFGIGLVAMVVIAQLEPR
FMARWVPVLYVIGVLLLVVVDVMGHNAMGATRWINIPGVIRFQPSEFLKIIMPATIAWYLSKRTLPPHLKHVAVSLALIG
VPFILIVRQPDLGTSLLILASGAFVLFMAGLRWRWIISVLAAAIPAAVAMWFFFMHDYQKQRVLTFLDPESDPLGTGWNI
IQSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLIIYMLLIGRGLVITAQAQTLFGKLLAG
ALTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVTLLSAFGVLMSIHTHRKWIAQV

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=367, Percent_Identity=54.4959128065395, Blast_Score=367, Evalue=1e-103,
Organism=Escherichia coli, GI1786277, Length=310, Percent_Identity=32.5806451612903, Blast_Score=159, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41755; Mature: 41755

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNFDRILSSEDVMRRRATFLQRIHIDGPLLILLLTLAAGSLFVLYSASGKNWDLLIKQ
CCCCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHEEEE
ASSFGIGLVAMVVIAQLEPRFMARWVPVLYVIGVLLLVVVDVMGHNAMGATRWINIPGVI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEE
RFQPSEFLKIIMPATIAWYLSKRTLPPHLKHVAVSLALIGVPFILIVRQPDLGTSLLILA
EECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
SGAFVLFMAGLRWRWIISVLAAAIPAAVAMWFFFMHDYQKQRVLTFLDPESDPLGTGWNI
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHH
IQSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLIIYMLLI
HHHHHCCCCCCCCCCCEEEECHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
GRGLVITAQAQTLFGKLLAGALTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVT
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHH
LLSAFGVLMSIHTHRKWIAQV
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSNFDRILSSEDVMRRRATFLQRIHIDGPLLILLLTLAAGSLFVLYSASGKNWDLLIKQ
CCCCHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCCCHHHEEEE
ASSFGIGLVAMVVIAQLEPRFMARWVPVLYVIGVLLLVVVDVMGHNAMGATRWINIPGVI
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCEEE
RFQPSEFLKIIMPATIAWYLSKRTLPPHLKHVAVSLALIGVPFILIVRQPDLGTSLLILA
EECHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
SGAFVLFMAGLRWRWIISVLAAAIPAAVAMWFFFMHDYQKQRVLTFLDPESDPLGTGWNI
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCHHH
IQSKAAIGSGGVFGKGWLLGTQSHLDFLPESHTDFIIAVLGEEFGLVGICALLIIYMLLI
HHHHHCCCCCCCCCCCEEEECHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
GRGLVITAQAQTLFGKLLAGALTMTFFVYVFVNIGMVSGLLPVVGVPLPFISYGGTSLVT
CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHH
LLSAFGVLMSIHTHRKWIAQV
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]