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The map label for this gene is yrbG [H]

Identifier: 66047395

GI number: 66047395

Start: 4957874

End: 4958905

Strand: Direct

Name: yrbG [H]

Synonym: Psyr_4168

Alternate gene names: 66047395

Gene position: 4957874-4958905 (Clockwise)

Preceding gene: 66047394

Following gene: 66047396

Centisome position: 81.36

GC content: 60.85

Gene sequence:

>1032_bases
ATGCTCAGTGGCTTGTTATTGCTGCTGATCGGGGCAGAACTGTCAGTGCGTGCAGCGGTGCATCTGGCGGCGATTTTCAA
GGTCCGGCCACTGATCGTCGGCCTGACCGTCGTGGCAATGGGCACCAGCGCGCCGCAGATGGCAGTAAGCCTGCAAGCCG
CGTTTGCCGATAACACCGACATCGCGGTGGGCAGTGTCATCGGCGGTAACATTTTCAATGTACTGGTGATCCTGGGCCTG
TGCGCGCTGATCATTCCGTTACGCGTTGCCCGTCAGGTGTTGCACGTCGACATTCCGCTGATGATCGGTGCCTGCCTGCT
GGCTATCGGCCTGTCGTGGAGCGGCGAATTCAGCAAGCTTGACGGCGCACTGCTGCTCGCCGGGTTGCTGTTCTGCCTGA
TCGTCATCATCCGTCAGGGCGGTCATGCGCCGCGTCACGGACATGCCGAGACAACCGCAAAACCTCGTACCTTCACGCGT
ATCCTCATGCTTGCCACTGGCCTGCTGCTGTTGACCGCTGGCGGACACCTGCTGGTCGACGCGTCAGTGGTGATTGCAAT
CCATCTTGGGCTGTCCGAACGCATCGTCGGCCTTACCATCATTGCCATCGGCACCTCATTGCCGGCACTGATGACCTCGC
TGATCGCAGCGTTTCGCGGCGAACGCGATATTGCCGTGGGCAACGTGATCGGCAGCAACCTGTTCAATCTGCTGGGCGTG
CTGGGGCTGACCGCACTGGTCGCCCCGGTGCCGCTGACGATCTCGCCAAATGCGCTGGTATTCGACCTGCCGATCATGCT
CGGCGTGTCGCTGCTGTGCGTGCCGCTGTTCTATTCCGGATACCGGATAGACCGTCTGGAAGGCCTGTTTCTGCTGTCGT
TGTACCTGACCTACGGGCTGCATATCCTGTCGATCAGCACCGGTATGGCGCTGGCCGAACGGCTTGAAAGCAAAATGCTC
ACGCTGGTGTTACCTGTGCTGGGCGCTGTGGTTGTCTGGGGCACGATCCGCGCCTGGCGACGCCAGCACTGA

Upstream 100 bases:

>100_bases
CCGTGTGCAGGCACTGGATTAAACCCAACCCCCGATCACCGCCAACAAGGACACTCGTATTCTCCAGCTATCGGCCCTGC
CCGCCCCCGCACTTATCCAG

Downstream 100 bases:

>100_bases
CCTCAATCCGCATCGATACAAGGAGCAAGGCCATGACAGACAAAACGATCAGCGACGGCGAACAGATCCGTCGCCAGGTG
ATGGGCGATGTCTACGTCGA

Product: K+-dependent Na+/Ca+ exchanger related-protein

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLSGLLLLLIGAELSVRAAVHLAAIFKVRPLIVGLTVVAMGTSAPQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGL
CALIIPLRVARQVLHVDIPLMIGACLLAIGLSWSGEFSKLDGALLLAGLLFCLIVIIRQGGHAPRHGHAETTAKPRTFTR
ILMLATGLLLLTAGGHLLVDASVVIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGV
LGLTALVAPVPLTISPNALVFDLPIMLGVSLLCVPLFYSGYRIDRLEGLFLLSLYLTYGLHILSISTGMALAERLESKML
TLVLPVLGAVVVWGTIRAWRRQH

Sequences:

>Translated_343_residues
MLSGLLLLLIGAELSVRAAVHLAAIFKVRPLIVGLTVVAMGTSAPQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGL
CALIIPLRVARQVLHVDIPLMIGACLLAIGLSWSGEFSKLDGALLLAGLLFCLIVIIRQGGHAPRHGHAETTAKPRTFTR
ILMLATGLLLLTAGGHLLVDASVVIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGV
LGLTALVAPVPLTISPNALVFDLPIMLGVSLLCVPLFYSGYRIDRLEGLFLLSLYLTYGLHILSISTGMALAERLESKML
TLVLPVLGAVVVWGTIRAWRRQH
>Mature_343_residues
MLSGLLLLLIGAELSVRAAVHLAAIFKVRPLIVGLTVVAMGTSAPQMAVSLQAAFADNTDIAVGSVIGGNIFNVLVILGL
CALIIPLRVARQVLHVDIPLMIGACLLAIGLSWSGEFSKLDGALLLAGLLFCLIVIIRQGGHAPRHGHAETTAKPRTFTR
ILMLATGLLLLTAGGHLLVDASVVIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGV
LGLTALVAPVPLTISPNALVFDLPIMLGVSLLCVPLFYSGYRIDRLEGLFLLSLYLTYGLHILSISTGMALAERLESKML
TLVLPVLGAVVVWGTIRAWRRQH

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300797299, Length=154, Percent_Identity=35.0649350649351, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI29788987, Length=154, Percent_Identity=35.0649350649351, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI300797277, Length=154, Percent_Identity=35.0649350649351, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789587, Length=274, Percent_Identity=40.5109489051095, Blast_Score=139, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24583109, Length=178, Percent_Identity=29.7752808988764, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24583111, Length=178, Percent_Identity=29.7752808988764, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 36119; Mature: 36119

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSGLLLLLIGAELSVRAAVHLAAIFKVRPLIVGLTVVAMGTSAPQMAVSLQAAFADNTD
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
IAVGSVIGGNIFNVLVILGLCALIIPLRVARQVLHVDIPLMIGACLLAIGLSWSGEFSKL
EEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHH
DGALLLAGLLFCLIVIIRQGGHAPRHGHAETTAKPRTFTRILMLATGLLLLTAGGHLLVD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEE
ASVVIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGV
CCEEEEEECCCCHHHHHEEEEHHHCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
LGLTALVAPVPLTISPNALVFDLPIMLGVSLLCVPLFYSGYRIDRLEGLFLLSLYLTYGL
HHHHHHHHCCCEEECCCCEEEECHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHH
HILSISTGMALAERLESKMLTLVLPVLGAVVVWGTIRAWRRQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLSGLLLLLIGAELSVRAAVHLAAIFKVRPLIVGLTVVAMGTSAPQMAVSLQAAFADNTD
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCC
IAVGSVIGGNIFNVLVILGLCALIIPLRVARQVLHVDIPLMIGACLLAIGLSWSGEFSKL
EEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHH
DGALLLAGLLFCLIVIIRQGGHAPRHGHAETTAKPRTFTRILMLATGLLLLTAGGHLLVD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEE
ASVVIAIHLGLSERIVGLTIIAIGTSLPALMTSLIAAFRGERDIAVGNVIGSNLFNLLGV
CCEEEEEECCCCHHHHHEEEEHHHCCHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
LGLTALVAPVPLTISPNALVFDLPIMLGVSLLCVPLFYSGYRIDRLEGLFLLSLYLTYGL
HHHHHHHHCCCEEECCCCEEEECHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHH
HILSISTGMALAERLESKMLTLVLPVLGAVVVWGTIRAWRRQH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]