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The map label for this gene is tctD [H]

Identifier: 66047192

GI number: 66047192

Start: 4712797

End: 4713468

Strand: Reverse

Name: tctD [H]

Synonym: Psyr_3965

Alternate gene names: 66047192

Gene position: 4713468-4712797 (Counterclockwise)

Preceding gene: 66047197

Following gene: 66047191

Centisome position: 77.35

GC content: 60.86

Gene sequence:

>672_bases
ATGCGTGTTCTTCTTGTGGAAGATCATCTGCAATTGGCTGAAAGTGTCGCGCAGGCGCTCAAAAGCGCGGGTTTGACCGT
TGATGTGCTGCATGATGGCGTGGCTGCCGACCTGGCGTTGAACAGCGAGGAATACGCCGTTGCCATTCTCGATGTCGGGT
TGCCGCGCATGGATGGCTTCGAAGTGCTGGCGCGTCTGCGCGCGCGCAGCAAAAACCTGCCGGTGCTGATGCTGACGGCG
CGCAGTGACGTCAAGGACCGGGTCCATGGCCTGAATCTGGGCGCCGACGACTACCTGGCCAAGCCTTTTGAACTCTCCGA
GCTGGAAGCCAGGGTCAAGGCCTTGCTGCGGCGCAGTGTGCTGGGTGGCGAGCGGCAACAGTGTTGCGGCGTGCTGGCCT
ACGATCTGGATACGCGACGTTTCACGCTTGGTGAAGAACTGCTGACCCTGACCTCTCGCGAACAGGCGGTGCTGGAAGCG
CTTATCGCCCGGCCGGGTCGGGTGATGAGCAAGGAGCAACTGGCGGCGCAGGTGTTCGGGCTCGATGAAGAAGCCAGCCC
CGACGCCATCGAGATCTATGTCCATCGTCTGCGGAAAAAGCTCGACGGGCATTCCGTGGCCATCGTGACCTTTCGCGGTC
TGGGGTATCTGCTGGAAAGCCGTGATGATTAA

Upstream 100 bases:

>100_bases
AGCGTTTCTGGCCTTCACAGACGGCGGCCGGCCTGTAAACTCCACCGCCACGAGCCTCGATACCCCGATCGATAACAACA
GTGACAATCAGGAGACGGCG

Downstream 100 bases:

>100_bases
CGACAGCCTGCGCTGGCGGTTGTTGTGGAACCTGGCCTTGCTGCTGGTGGTGTTGATGCTGGCCAGCGGCATGAGCGCTT
ACTGGAATGGCCGCGAAGTG

Product: response regulator receiver:transcriptional regulatory protein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRVLLVEDHLQLAESVAQALKSAGLTVDVLHDGVAADLALNSEEYAVAILDVGLPRMDGFEVLARLRARSKNLPVLMLTA
RSDVKDRVHGLNLGADDYLAKPFELSELEARVKALLRRSVLGGERQQCCGVLAYDLDTRRFTLGEELLTLTSREQAVLEA
LIARPGRVMSKEQLAAQVFGLDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDD

Sequences:

>Translated_223_residues
MRVLLVEDHLQLAESVAQALKSAGLTVDVLHDGVAADLALNSEEYAVAILDVGLPRMDGFEVLARLRARSKNLPVLMLTA
RSDVKDRVHGLNLGADDYLAKPFELSELEARVKALLRRSVLGGERQQCCGVLAYDLDTRRFTLGEELLTLTSREQAVLEA
LIARPGRVMSKEQLAAQVFGLDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDD
>Mature_223_residues
MRVLLVEDHLQLAESVAQALKSAGLTVDVLHDGVAADLALNSEEYAVAILDVGLPRMDGFEVLARLRARSKNLPVLMLTA
RSDVKDRVHGLNLGADDYLAKPFELSELEARVKALLRRSVLGGERQQCCGVLAYDLDTRRFTLGEELLTLTSREQAVLEA
LIARPGRVMSKEQLAAQVFGLDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDD

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=38.1165919282511, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=41.2844036697248, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=38.2222222222222, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=38.2222222222222, Blast_Score=143, Evalue=9e-36,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=37.1559633027523, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=34.3612334801762, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=36, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=36.1990950226244, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=36.3636363636364, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=34.2342342342342, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=31.25, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=27.7533039647577, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790299, Length=125, Percent_Identity=34.4, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=33.0434782608696, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=30.1724137931034, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=24.2424242424242, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=32.2314049586777, Blast_Score=60, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24588; Mature: 24588

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLVEDHLQLAESVAQALKSAGLTVDVLHDGVAADLALNSEEYAVAILDVGLPRMDGF
CEEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHEEECCCCEEEEEEECCCCCCCHH
EVLARLRARSKNLPVLMLTARSDVKDRVHGLNLGADDYLAKPFELSELEARVKALLRRSV
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
LGGERQQCCGVLAYDLDTRRFTLGEELLTLTSREQAVLEALIARPGRVMSKEQLAAQVFG
CCCCHHHHHHHHEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
LDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDD
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCC
>Mature Secondary Structure
MRVLLVEDHLQLAESVAQALKSAGLTVDVLHDGVAADLALNSEEYAVAILDVGLPRMDGF
CEEEEEHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHEEECCCCEEEEEEECCCCCCCHH
EVLARLRARSKNLPVLMLTARSDVKDRVHGLNLGADDYLAKPFELSELEARVKALLRRSV
HHHHHHHHCCCCCCEEEEECCCCHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
LGGERQQCCGVLAYDLDTRRFTLGEELLTLTSREQAVLEALIARPGRVMSKEQLAAQVFG
CCCCHHHHHHHHEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHC
LDEEASPDAIEIYVHRLRKKLDGHSVAIVTFRGLGYLLESRDD
CCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]