Click here to switch to the map view.

The map label for this gene is ung [H]

Identifier: 66047197

GI number: 66047197

Start: 4718010

End: 4718702

Strand: Reverse

Name: ung [H]

Synonym: Psyr_3970

Alternate gene names: 66047197

Gene position: 4718702-4718010 (Counterclockwise)

Preceding gene: 66047198

Following gene: 66047192

Centisome position: 77.44

GC content: 58.87

Gene sequence:

>693_bases
ATGACTAGCGACGACCGCATCAAGCTTGAGCCCAGCTGGAAAAACGCCCTGCGTGACGAATTCGAACAACCCTACATGGC
TCAATTGCGCGAGTTTCTGCGTCAGGAGCACGCGGCGGGCAAGGAAATCTATCCGCCCGGTCCGCTGATTTTCAATGCGT
TGAACTCCACGCCGCTGGATAACGTGAAAGTGGTCATTCTTGGCCAGGATCCGTATCACGGCCCGAATCAGGCGCATGGT
CTGTGCTTCTCGGTGCAACCGGGTGTGCCGACGCCGCCATCGCTGGTCAACATCTACAAAGAGCTGAAACGCGACCTGAA
CATCGATATTCCGAACCACGGTTGCCTGCAATCCTGGGCTGATCAGGGCGTGCTGTTGCTGAACACCACCCTGACCGTCG
AACGTGCCAACGCGGCGTCGCATGCGGGCAAAGGCTGGCAGCACTTCACTGACCGGATCATCCAGGTGGTCAGCGAGCAT
CAGCCGCATCTGGTGTTCCTGCTGTGGGGCGCTCATGCGCAGAGCAAGCAGAAACTGGTCGATGCGACCAAGCATCTGGT
GCTGACCTCTGTCCATCCTTCGCCGTTGTCAGCCTACAAAGGCTTCCTGGGCAACGGGCACTTCGGGCGGGCCAACAAGT
ACCTTGAGCAAAACGGCATCGCGCCGATTGACTGGCGCTTGCCTGCGCTCTGA

Upstream 100 bases:

>100_bases
GACGCTCTGCGTCCGATCTTGAAGGCGCATAGCGCGACCGGCATTGACTTTGCTGCCCGGCTTTCCTAGTGTCCGCGCAT
TGTTTTTACCGGATGTAACC

Downstream 100 bases:

>100_bases
TTTGAATTTGAAAGGGTTCCAGCGACCTGTTCAGTCAGCGAGCCGTTTGTTCCAGCGTCGGTACAGCGGCTCGGCGAGAA
ACAGCACGAACAGCAGGCGC

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTSDDRIKLEPSWKNALRDEFEQPYMAQLREFLRQEHAAGKEIYPPGPLIFNALNSTPLDNVKVVILGQDPYHGPNQAHG
LCFSVQPGVPTPPSLVNIYKELKRDLNIDIPNHGCLQSWADQGVLLLNTTLTVERANAASHAGKGWQHFTDRIIQVVSEH
QPHLVFLLWGAHAQSKQKLVDATKHLVLTSVHPSPLSAYKGFLGNGHFGRANKYLEQNGIAPIDWRLPAL

Sequences:

>Translated_230_residues
MTSDDRIKLEPSWKNALRDEFEQPYMAQLREFLRQEHAAGKEIYPPGPLIFNALNSTPLDNVKVVILGQDPYHGPNQAHG
LCFSVQPGVPTPPSLVNIYKELKRDLNIDIPNHGCLQSWADQGVLLLNTTLTVERANAASHAGKGWQHFTDRIIQVVSEH
QPHLVFLLWGAHAQSKQKLVDATKHLVLTSVHPSPLSAYKGFLGNGHFGRANKYLEQNGIAPIDWRLPAL
>Mature_229_residues
TSDDRIKLEPSWKNALRDEFEQPYMAQLREFLRQEHAAGKEIYPPGPLIFNALNSTPLDNVKVVILGQDPYHGPNQAHGL
CFSVQPGVPTPPSLVNIYKELKRDLNIDIPNHGCLQSWADQGVLLLNTTLTVERANAASHAGKGWQHFTDRIIQVVSEHQ
PHLVFLLWGAHAQSKQKLVDATKHLVLTSVHPSPLSAYKGFLGNGHFGRANKYLEQNGIAPIDWRLPAL

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=216, Percent_Identity=50.9259259259259, Blast_Score=221, Evalue=5e-58,
Organism=Homo sapiens, GI6224979, Length=216, Percent_Identity=50.9259259259259, Blast_Score=221, Evalue=6e-58,
Organism=Escherichia coli, GI1788934, Length=222, Percent_Identity=53.6036036036036, Blast_Score=243, Evalue=8e-66,
Organism=Caenorhabditis elegans, GI17556304, Length=216, Percent_Identity=49.0740740740741, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6323620, Length=239, Percent_Identity=45.1882845188285, Blast_Score=191, Evalue=1e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 25695; Mature: 25563

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSDDRIKLEPSWKNALRDEFEQPYMAQLREFLRQEHAAGKEIYPPGPLIFNALNSTPLD
CCCCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHEECCCCCCCCC
NVKVVILGQDPYHGPNQAHGLCFSVQPGVPTPPSLVNIYKELKRDLNIDIPNHGCLQSWA
CEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
DQGVLLLNTTLTVERANAASHAGKGWQHFTDRIIQVVSEHQPHLVFLLWGAHAQSKQKLV
CCCEEEEEEEEEEECCCCHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
DATKHLVLTSVHPSPLSAYKGFLGNGHFGRANKYLEQNGIAPIDWRLPAL
HHHHHEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TSDDRIKLEPSWKNALRDEFEQPYMAQLREFLRQEHAAGKEIYPPGPLIFNALNSTPLD
CCCCCEEECCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHEECCCCCCCCC
NVKVVILGQDPYHGPNQAHGLCFSVQPGVPTPPSLVNIYKELKRDLNIDIPNHGCLQSWA
CEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHH
DQGVLLLNTTLTVERANAASHAGKGWQHFTDRIIQVVSEHQPHLVFLLWGAHAQSKQKLV
CCCEEEEEEEEEEECCCCHHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHH
DATKHLVLTSVHPSPLSAYKGFLGNGHFGRANKYLEQNGIAPIDWRLPAL
HHHHHEEEEECCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA