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The map label for this gene is rssA [H]

Identifier: 66047191

GI number: 66047191

Start: 4711422

End: 4712804

Strand: Reverse

Name: rssA [H]

Synonym: Psyr_3964

Alternate gene names: 66047191

Gene position: 4712804-4711422 (Counterclockwise)

Preceding gene: 66047192

Following gene: 66047188

Centisome position: 77.34

GC content: 64.43

Gene sequence:

>1383_bases
ATGATTAACGACAGCCTGCGCTGGCGGTTGTTGTGGAACCTGGCCTTGCTGCTGGTGGTGTTGATGCTGGCCAGCGGCAT
GAGCGCTTACTGGAATGGCCGCGAAGTGGCCGACACCGCCTATGACCGCACATTGCTGGCTTCCGCGCGGACCATCGCTG
CCGGCCTGACCCAGCGTGATGGGACGCTGAGCGCCGACATCCCCTACGTGGCGCTGGATACCTTCGCCTACGACAGCGAA
GGGCGCATCTACTATCAGGTCAATGACATTCATCAGAAGCTGATTTCCGGCTATGAAAACCTGCCTTCGCCGCCGCCCGG
TACCTTGCGTACCGACGATTACCCGGCCCTGGCGAAATTTTATAACGGAACCTATCAGGGGCAGGATGTGCGTGTCGTCA
GCCTGCTCAAGCCGGTGACCGACCCGGGCATGAACGGTACCGCTGAAATCCGCGTTGCCGAAACCCAGGAAGCGCGCAAG
GGCATGGCGCGCAGCCTGATGGCCGACACATTGCTGCGCCTGGGCATGCTCGGAGGGGGCGCGCTGCTGCTGGTCTGGTT
CACGGTAAGCGCGGCATTGCGACCGCTGGAGCGGCTGCGTACTGCCGTCGAGGAGCGTCAGCCGGATGATCTGCGCGCGT
TGCCGATGGTTGAGGTGCAGCACGAACTGCGTCCGTTGGTGGGCGCGCTGAACCACTTTACCGAGCGACTGCGCGTGCAA
TTCGAGCGTCAGGCGCAATTCATTGCCGATGCCGCCCACGAACTGCGCACCCCGCTGGCCGCCTTGAAGGCGCGGGTCGA
ACTGGGGCTGCGCGAACGCGACCCGCAGCATTGGCGCAGCACGCTGGAGTCGGCGGCGCTTGGCACCGATCGACTCACGC
ATCTGGCTAACCAGTTGCTGTCCCTGGCGCGCATCGAAAACGGCGCGCGGGCCATCGCCGAGGGTGGGGCGCAACAGCTG
GACCTCAGTCAACTGGCCAGGGAGCTGGGCATGGCCATGGCGCCGTTGGCTCATTCCCGGGGCGTGGCGCTGGCGCTGGA
GGCTGACGAGCCGGTCTGGCTGCGCGGCGAGCCGACCTTGCTGAACGAGTTACTGAGCAATCTGATCGACAACGCGCTGG
CCCACACTTCACCGGGCGGCAACGTGGTGTTGCGGGTCTATGCGCCGGGTGTTCTAGAGGTGGAGGATGATGGCCCCGGC
ATTCCGCCTGATGAACGTGAGCGCGTGTTCGAGCGTTTTTACCGTCGCAGCCAGCAGGGCAGTGGTGCCGGGCTCGGGCT
GGCGATTGTGGGTGAAATCTGCCGGGCACATCTGGCCAGAATCACCTTGCACGAGGGCGCCGAGCGCGGCTTGAAGGTAA
GGGTCAGTTTCAGCGCCACCTGA

Upstream 100 bases:

>100_bases
GCCATCGAGATCTATGTCCATCGTCTGCGGAAAAAGCTCGACGGGCATTCCGTGGCCATCGTGACCTTTCGCGGTCTGGG
GTATCTGCTGGAAAGCCGTG

Downstream 100 bases:

>100_bases
TGGGTCGAGGCTAGTAGAGCATGCTCTTGGCTTCGTCCATCTGGGCGCTGAGCACGTCTTCGGCTCTGGCAAGTCTCAAC
TGGCTGTAGGCAGGCAGGTC

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MINDSLRWRLLWNLALLLVVLMLASGMSAYWNGREVADTAYDRTLLASARTIAAGLTQRDGTLSADIPYVALDTFAYDSE
GRIYYQVNDIHQKLISGYENLPSPPPGTLRTDDYPALAKFYNGTYQGQDVRVVSLLKPVTDPGMNGTAEIRVAETQEARK
GMARSLMADTLLRLGMLGGGALLLVWFTVSAALRPLERLRTAVEERQPDDLRALPMVEVQHELRPLVGALNHFTERLRVQ
FERQAQFIADAAHELRTPLAALKARVELGLRERDPQHWRSTLESAALGTDRLTHLANQLLSLARIENGARAIAEGGAQQL
DLSQLARELGMAMAPLAHSRGVALALEADEPVWLRGEPTLLNELLSNLIDNALAHTSPGGNVVLRVYAPGVLEVEDDGPG
IPPDERERVFERFYRRSQQGSGAGLGLAIVGEICRAHLARITLHEGAERGLKVRVSFSAT

Sequences:

>Translated_460_residues
MINDSLRWRLLWNLALLLVVLMLASGMSAYWNGREVADTAYDRTLLASARTIAAGLTQRDGTLSADIPYVALDTFAYDSE
GRIYYQVNDIHQKLISGYENLPSPPPGTLRTDDYPALAKFYNGTYQGQDVRVVSLLKPVTDPGMNGTAEIRVAETQEARK
GMARSLMADTLLRLGMLGGGALLLVWFTVSAALRPLERLRTAVEERQPDDLRALPMVEVQHELRPLVGALNHFTERLRVQ
FERQAQFIADAAHELRTPLAALKARVELGLRERDPQHWRSTLESAALGTDRLTHLANQLLSLARIENGARAIAEGGAQQL
DLSQLARELGMAMAPLAHSRGVALALEADEPVWLRGEPTLLNELLSNLIDNALAHTSPGGNVVLRVYAPGVLEVEDDGPG
IPPDERERVFERFYRRSQQGSGAGLGLAIVGEICRAHLARITLHEGAERGLKVRVSFSAT
>Mature_460_residues
MINDSLRWRLLWNLALLLVVLMLASGMSAYWNGREVADTAYDRTLLASARTIAAGLTQRDGTLSADIPYVALDTFAYDSE
GRIYYQVNDIHQKLISGYENLPSPPPGTLRTDDYPALAKFYNGTYQGQDVRVVSLLKPVTDPGMNGTAEIRVAETQEARK
GMARSLMADTLLRLGMLGGGALLLVWFTVSAALRPLERLRTAVEERQPDDLRALPMVEVQHELRPLVGALNHFTERLRVQ
FERQAQFIADAAHELRTPLAALKARVELGLRERDPQHWRSTLESAALGTDRLTHLANQLLSLARIENGARAIAEGGAQQL
DLSQLARELGMAMAPLAHSRGVALALEADEPVWLRGEPTLLNELLSNLIDNALAHTSPGGNVVLRVYAPGVLEVEDDGPG
IPPDERERVFERFYRRSQQGSGAGLGLAIVGEICRAHLARITLHEGAERGLKVRVSFSAT

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=345, Percent_Identity=32.463768115942, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786783, Length=306, Percent_Identity=31.3725490196078, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790551, Length=272, Percent_Identity=29.4117647058824, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=30.4029304029304, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788279, Length=306, Percent_Identity=26.1437908496732, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=31.2775330396476, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790346, Length=269, Percent_Identity=29.368029739777, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1790861, Length=333, Percent_Identity=29.4294294294294, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787374, Length=279, Percent_Identity=26.8817204301075, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786912, Length=274, Percent_Identity=29.5620437956204, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=198, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1789149, Length=220, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788713, Length=226, Percent_Identity=26.1061946902655, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787894, Length=226, Percent_Identity=32.3008849557522, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994928, Length=266, Percent_Identity=26.3157894736842, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081816, Length=310, Percent_Identity=26.4516129032258, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082128, Length=252, Percent_Identity=26.984126984127, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=27.3913043478261, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1789808, Length=241, Percent_Identity=25.7261410788382, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50551; Mature: 50551

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDSLRWRLLWNLALLLVVLMLASGMSAYWNGREVADTAYDRTLLASARTIAAGLTQRD
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GTLSADIPYVALDTFAYDSEGRIYYQVNDIHQKLISGYENLPSPPPGTLRTDDYPALAKF
CCEECCCCEEEEEEEEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
YNGTYQGQDVRVVSLLKPVTDPGMNGTAEIRVAETQEARKGMARSLMADTLLRLGMLGGG
HCCCCCCCCEEHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCH
ALLLVWFTVSAALRPLERLRTAVEERQPDDLRALPMVEVQHELRPLVGALNHFTERLRVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FERQAQFIADAAHELRTPLAALKARVELGLRERDPQHWRSTLESAALGTDRLTHLANQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
SLARIENGARAIAEGGAQQLDLSQLARELGMAMAPLAHSRGVALALEADEPVWLRGEPTL
HHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHCHHCCCCEEEEEECCCCEEECCCHHH
LNELLSNLIDNALAHTSPGGNVVLRVYAPGVLEVEDDGPGIPPDERERVFERFYRRSQQG
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
SGAGLGLAIVGEICRAHLARITLHEGAERGLKVRVSFSAT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC
>Mature Secondary Structure
MINDSLRWRLLWNLALLLVVLMLASGMSAYWNGREVADTAYDRTLLASARTIAAGLTQRD
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
GTLSADIPYVALDTFAYDSEGRIYYQVNDIHQKLISGYENLPSPPPGTLRTDDYPALAKF
CCEECCCCEEEEEEEEECCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
YNGTYQGQDVRVVSLLKPVTDPGMNGTAEIRVAETQEARKGMARSLMADTLLRLGMLGGG
HCCCCCCCCEEHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCH
ALLLVWFTVSAALRPLERLRTAVEERQPDDLRALPMVEVQHELRPLVGALNHFTERLRVQ
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FERQAQFIADAAHELRTPLAALKARVELGLRERDPQHWRSTLESAALGTDRLTHLANQLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
SLARIENGARAIAEGGAQQLDLSQLARELGMAMAPLAHSRGVALALEADEPVWLRGEPTL
HHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHCHHCCCCEEEEEECCCCEEECCCHHH
LNELLSNLIDNALAHTSPGGNVVLRVYAPGVLEVEDDGPGIPPDERERVFERFYRRSQQG
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCC
SGAGLGLAIVGEICRAHLARITLHEGAERGLKVRVSFSAT
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA