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The map label for this gene is pdxH [H]

Identifier: 66047080

GI number: 66047080

Start: 4592204

End: 4592851

Strand: Reverse

Name: pdxH [H]

Synonym: Psyr_3853

Alternate gene names: 66047080

Gene position: 4592851-4592204 (Counterclockwise)

Preceding gene: 66047081

Following gene: 66047079

Centisome position: 75.37

GC content: 60.19

Gene sequence:

>648_bases
ATGACCCAGACCCTGGCCGATATGCGCCGTGATTACACGCGCGACGGGTTGACCGAAGCGCAATCGCCGGACGAGCCCTT
TGCACTCTTCCATGCATGGTTCGCCGATGCGGTGAACACCGAGCAGCCGCCTGTCGAGGCTAACGCCATGACATTGGCGA
CGGTTGATGAGGAAGGACGTCCACATTGCCGCGTCTTGCTGCTCAAGGGCCTCGACACTCAGGGTTTCACGTTTTTCACC
AACTACGAAAGCGCCAAGGGCCAGCAACTGGCTGCCCGTCCATTTGCTGCGATGACTTTCTTCTGGCCGACACTGGAGCG
CCAGGTGCGTATCGAGGGGCGGGTCGAGAAAGTCTCTGCGCAGGAGTCCGACGCTTATTACCAGGTGCGCCCTCTGGGCA
GTCGTCTGGGGGCATGGGCCTCGCCACAGAGTCGTGTAATCGCGGATCGCGACGAGCTGGAAGGCTTGATCAGACAGACG
GAACAACGCTTCGCAGACACCCGGCCACACTGCCCCGAGCACTGGGGTGGCTATCGTCTTTTGCCCGAGCGAATCGAGTT
CTGGCAGGGTCGCTCCAGTCGACTTCACGACCGTTTGAACTATCGTTTGATAGACGACAGATGGACACGTGAGCGCCTTG
CACCCTGA

Upstream 100 bases:

>100_bases
AGGATGACAGCCAGGCCAGTAACTAAGCCTGTCAGCACCCACGCGGATCGTCACTGACGCTTCGCGTGGAGTCGATCCGT
GACCTCGCAGGAACCAGACC

Downstream 100 bases:

>100_bases
TTGAATTATTCGTTTGGCCAATCGTCTGAGCGTTATACGGGCTATGGCTGTATGAGGCCTGAATCAATTTAATTTGCAGG
CTCGGGGCCGTGACAGCACC

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MTQTLADMRRDYTRDGLTEAQSPDEPFALFHAWFADAVNTEQPPVEANAMTLATVDEEGRPHCRVLLLKGLDTQGFTFFT
NYESAKGQQLAARPFAAMTFFWPTLERQVRIEGRVEKVSAQESDAYYQVRPLGSRLGAWASPQSRVIADRDELEGLIRQT
EQRFADTRPHCPEHWGGYRLLPERIEFWQGRSSRLHDRLNYRLIDDRWTRERLAP

Sequences:

>Translated_215_residues
MTQTLADMRRDYTRDGLTEAQSPDEPFALFHAWFADAVNTEQPPVEANAMTLATVDEEGRPHCRVLLLKGLDTQGFTFFT
NYESAKGQQLAARPFAAMTFFWPTLERQVRIEGRVEKVSAQESDAYYQVRPLGSRLGAWASPQSRVIADRDELEGLIRQT
EQRFADTRPHCPEHWGGYRLLPERIEFWQGRSSRLHDRLNYRLIDDRWTRERLAP
>Mature_214_residues
TQTLADMRRDYTRDGLTEAQSPDEPFALFHAWFADAVNTEQPPVEANAMTLATVDEEGRPHCRVLLLKGLDTQGFTFFTN
YESAKGQQLAARPFAAMTFFWPTLERQVRIEGRVEKVSAQESDAYYQVRPLGSRLGAWASPQSRVIADRDELEGLIRQTE
QRFADTRPHCPEHWGGYRLLPERIEFWQGRSSRLHDRLNYRLIDDRWTRERLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=230, Percent_Identity=42.1739130434783, Blast_Score=173, Evalue=1e-43,
Organism=Escherichia coli, GI1787926, Length=213, Percent_Identity=41.7840375586854, Blast_Score=172, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI17553712, Length=204, Percent_Identity=43.1372549019608, Blast_Score=166, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6319509, Length=211, Percent_Identity=45.0236966824645, Blast_Score=172, Evalue=3e-44,
Organism=Drosophila melanogaster, GI45551845, Length=205, Percent_Identity=40.9756097560976, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24644901, Length=205, Percent_Identity=40.9756097560976, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24644903, Length=191, Percent_Identity=26.1780104712042, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24958; Mature: 24827

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTLADMRRDYTRDGLTEAQSPDEPFALFHAWFADAVNTEQPPVEANAMTLATVDEEGR
CCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
PHCRVLLLKGLDTQGFTFFTNYESAKGQQLAARPFAAMTFFWPTLERQVRIEGRVEKVSA
CCEEEEEEECCCCCCEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHEEEECCHHHHHCC
QESDAYYQVRPLGSRLGAWASPQSRVIADRDELEGLIRQTEQRFADTRPHCPEHWGGYRL
CCCCCEEEEEECHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LPERIEFWQGRSSRLHDRLNYRLIDDRWTRERLAP
CHHHHHHHCCCCHHHHHHCCEEEECCCHHHHHCCC
>Mature Secondary Structure 
TQTLADMRRDYTRDGLTEAQSPDEPFALFHAWFADAVNTEQPPVEANAMTLATVDEEGR
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCC
PHCRVLLLKGLDTQGFTFFTNYESAKGQQLAARPFAAMTFFWPTLERQVRIEGRVEKVSA
CCEEEEEEECCCCCCEEEEECCCCCCCCHHHHCCHHHHHHHHHHHHHEEEECCHHHHHCC
QESDAYYQVRPLGSRLGAWASPQSRVIADRDELEGLIRQTEQRFADTRPHCPEHWGGYRL
CCCCCEEEEEECHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LPERIEFWQGRSSRLHDRLNYRLIDDRWTRERLAP
CHHHHHHHCCCCHHHHHHCCEEEECCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA