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The map label for this gene is mtaD [H]

Identifier: 66046878

GI number: 66046878

Start: 4334816

End: 4336147

Strand: Direct

Name: mtaD [H]

Synonym: Psyr_3649

Alternate gene names: 66046878

Gene position: 4334816-4336147 (Clockwise)

Preceding gene: 66046863

Following gene: 66046879

Centisome position: 71.14

GC content: 64.19

Gene sequence:

>1332_bases
ATGCCGAACGCTACAGCACCGCTCGACCTTTTGCTCCTGCCCGCCTGGCTGGTGCCGGTCGAGCCCGCAGGCGTCGTGCT
CAAGGACCACGGCATCGGCATTCGCGATGGCTGTATCGCTTATATCGGTCCACGCGCCGACGCGCTGCGGCAGAACGCCG
TGCAGGTTCTGGAACTGCCTGGCATGCTGCTCAGCCCCGGCCTGATCAACGCCCACGGCCATGCGGCGATGACCCTGTTT
CGCGGGCTGGCCGACGATCTGCCGCTGATGACCTGGCTGCAGGACCACATCTGGCCCGCCGAAGGCAAGTGGGTCGATGA
AGACTTCGTGCGTGACGGCACCGATCTGGCCATCGCCGAGCAGCTCAAGGGCGGCATCACGTGTTTTTCCGACATGTATT
TCTACCCCAAGGTGGCCGCCGAACGCGTCCATGCCAGCGGCATGCGCGCGCAGATCACCGTCCCGGTGCTGGATTTTCCG
ATTCCAGGTGCCCACACCACGGCTGAAGCCCTGCACAACGGCATCGAACTGTTCAACGACCTCGTTCACCATCCACGCAT
CAAAATCGCCTTCGGCCCGCATGCGCCCTATACCGTGAGCGATGAGAACCTGGAGAAGGTCCGGGTGATCGCCGACGAGC
TGGATGCCACGATCCAGATGCACGTGCACGAGACCGCATTTGAGGTCGAGCAGGCTGTCGAGCAACGCCAGGAGCGCCCC
CTCGCCCGCCTCAACCGGCTGGGCATGCTCGGGCCGCGCTTCCAGGCCGTGCACATGACGCAGATCAGCGACGACGATCT
GGCCCTGCTGGTGGAAAGCAACACCAACGTCATTCATTGCCCGGAATCCAATCTCAAACTGGCCAGCGGTTTCTGCCCGG
TCGAACGACTGTGGCAGGCGGGTGTGAACGTTGCGGTAGGCACCGACGGTGCCGCCAGCAACAATGACCTGGACCTGCTC
GGCGAAACCCGCACCGCCGCCTTGCTGGCCAAGGCTGTCGCCGGCTCGGCCACGGCGCTGGATGCACACCGCGCGCTGCG
CATGGCAACGCTCAATGGCGCTCGCGCCCTGGGTATTCAGGCCGAAACCGGCTCGCTGGAGATCGGCAAGGCGGCGGACA
TGGTCGCTTTCGACCTGTCGGGCCTGGCCCAGCAACCGATTTACGACCCGGTGTCGCAGCTTATATATGCCACTGGCCGC
GATTGCGTGAGTCATGTCTGGGTGGCCGGCAAACAATTGCTCGACGCTCGCCGGCTGACCCGCATGGATGAGCCCGCACT
GCGCGACACCGCGATTGCGTGGGGCCAGCGTATTTCCGGTAAAGCCGAATAA

Upstream 100 bases:

>100_bases
TCCGAAACCCAGCATCAAAAGCCGCTGATTATAGCGAGCCGCCTGCGAAGACGCTCGGGTATACTTCGTCATCAACGTAA
TAAACGATGGAAACCTTCTC

Downstream 100 bases:

>100_bases
TTCGATTCGGACCGAACACATGTCAGTCAGGCTTATCTATAAGCCTGACTGACGAAAAAGAATTTTGAGTTCAAGAGGGA
CACCCATGAGCAACGTCGAC

Product: N-ethylammeline chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MPNATAPLDLLLLPAWLVPVEPAGVVLKDHGIGIRDGCIAYIGPRADALRQNAVQVLELPGMLLSPGLINAHGHAAMTLF
RGLADDLPLMTWLQDHIWPAEGKWVDEDFVRDGTDLAIAEQLKGGITCFSDMYFYPKVAAERVHASGMRAQITVPVLDFP
IPGAHTTAEALHNGIELFNDLVHHPRIKIAFGPHAPYTVSDENLEKVRVIADELDATIQMHVHETAFEVEQAVEQRQERP
LARLNRLGMLGPRFQAVHMTQISDDDLALLVESNTNVIHCPESNLKLASGFCPVERLWQAGVNVAVGTDGAASNNDLDLL
GETRTAALLAKAVAGSATALDAHRALRMATLNGARALGIQAETGSLEIGKAADMVAFDLSGLAQQPIYDPVSQLIYATGR
DCVSHVWVAGKQLLDARRLTRMDEPALRDTAIAWGQRISGKAE

Sequences:

>Translated_443_residues
MPNATAPLDLLLLPAWLVPVEPAGVVLKDHGIGIRDGCIAYIGPRADALRQNAVQVLELPGMLLSPGLINAHGHAAMTLF
RGLADDLPLMTWLQDHIWPAEGKWVDEDFVRDGTDLAIAEQLKGGITCFSDMYFYPKVAAERVHASGMRAQITVPVLDFP
IPGAHTTAEALHNGIELFNDLVHHPRIKIAFGPHAPYTVSDENLEKVRVIADELDATIQMHVHETAFEVEQAVEQRQERP
LARLNRLGMLGPRFQAVHMTQISDDDLALLVESNTNVIHCPESNLKLASGFCPVERLWQAGVNVAVGTDGAASNNDLDLL
GETRTAALLAKAVAGSATALDAHRALRMATLNGARALGIQAETGSLEIGKAADMVAFDLSGLAQQPIYDPVSQLIYATGR
DCVSHVWVAGKQLLDARRLTRMDEPALRDTAIAWGQRISGKAE
>Mature_442_residues
PNATAPLDLLLLPAWLVPVEPAGVVLKDHGIGIRDGCIAYIGPRADALRQNAVQVLELPGMLLSPGLINAHGHAAMTLFR
GLADDLPLMTWLQDHIWPAEGKWVDEDFVRDGTDLAIAEQLKGGITCFSDMYFYPKVAAERVHASGMRAQITVPVLDFPI
PGAHTTAEALHNGIELFNDLVHHPRIKIAFGPHAPYTVSDENLEKVRVIADELDATIQMHVHETAFEVEQAVEQRQERPL
ARLNRLGMLGPRFQAVHMTQISDDDLALLVESNTNVIHCPESNLKLASGFCPVERLWQAGVNVAVGTDGAASNNDLDLLG
ETRTAALLAKAVAGSATALDAHRALRMATLNGARALGIQAETGSLEIGKAADMVAFDLSGLAQQPIYDPVSQLIYATGRD
CVSHVWVAGKQLLDARRLTRMDEPALRDTAIAWGQRISGKAE

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=436, Percent_Identity=25.9174311926606, Blast_Score=126, Evalue=3e-29,
Organism=Escherichia coli, GI1789249, Length=403, Percent_Identity=25.0620347394541, Blast_Score=108, Evalue=8e-25,
Organism=Escherichia coli, GI87082177, Length=412, Percent_Identity=22.5728155339806, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17540282, Length=393, Percent_Identity=25.6997455470738, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319963, Length=382, Percent_Identity=21.4659685863874, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643849, Length=382, Percent_Identity=27.7486910994764, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 47927; Mature: 47796

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNATAPLDLLLLPAWLVPVEPAGVVLKDHGIGIRDGCIAYIGPRADALRQNAVQVLELP
CCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHCC
GMLLSPGLINAHGHAAMTLFRGLADDLPLMTWLQDHIWPAEGKWVDEDFVRDGTDLAIAE
CHHHCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHH
QLKGGITCFSDMYFYPKVAAERVHASGMRAQITVPVLDFPIPGAHTTAEALHNGIELFND
HHCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHH
LVHHPRIKIAFGPHAPYTVSDENLEKVRVIADELDATIQMHVHETAFEVEQAVEQRQERP
HHHCCEEEEEECCCCCEEECCCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHCH
LARLNRLGMLGPRFQAVHMTQISDDDLALLVESNTNVIHCPESNLKLASGFCPVERLWQA
HHHHHHCCCCCCCEEEEEEEEECCCCEEEEEECCCCEEECCCCCCEEECCCCCHHHHHHC
GVNVAVGTDGAASNNDLDLLGETRTAALLAKAVAGSATALDAHRALRMATLNGARALGIQ
CCEEEECCCCCCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEE
AETGSLEIGKAADMVAFDLSGLAQQPIYDPVSQLIYATGRDCVSHVWVAGKQLLDARRLT
ECCCCEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RMDEPALRDTAIAWGQRISGKAE
CCCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PNATAPLDLLLLPAWLVPVEPAGVVLKDHGIGIRDGCIAYIGPRADALRQNAVQVLELP
CCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHCC
GMLLSPGLINAHGHAAMTLFRGLADDLPLMTWLQDHIWPAEGKWVDEDFVRDGTDLAIAE
CHHHCCCEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHH
QLKGGITCFSDMYFYPKVAAERVHASGMRAQITVPVLDFPIPGAHTTAEALHNGIELFND
HHCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHH
LVHHPRIKIAFGPHAPYTVSDENLEKVRVIADELDATIQMHVHETAFEVEQAVEQRQERP
HHHCCEEEEEECCCCCEEECCCCHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHCH
LARLNRLGMLGPRFQAVHMTQISDDDLALLVESNTNVIHCPESNLKLASGFCPVERLWQA
HHHHHHCCCCCCCEEEEEEEEECCCCEEEEEECCCCEEECCCCCCEEECCCCCHHHHHHC
GVNVAVGTDGAASNNDLDLLGETRTAALLAKAVAGSATALDAHRALRMATLNGARALGIQ
CCEEEECCCCCCCCCCCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEE
AETGSLEIGKAADMVAFDLSGLAQQPIYDPVSQLIYATGRDCVSHVWVAGKQLLDARRLT
ECCCCEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
RMDEPALRDTAIAWGQRISGKAE
CCCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA