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The map label for this gene is ampC [H]

Identifier: 66046593

GI number: 66046593

Start: 4022628

End: 4023785

Strand: Direct

Name: ampC [H]

Synonym: Psyr_3364

Alternate gene names: 66046593

Gene position: 4022628-4023785 (Clockwise)

Preceding gene: 66046590

Following gene: 66046596

Centisome position: 66.01

GC content: 59.07

Gene sequence:

>1158_bases
ATGCAATGGAATGGAGCGCTGCTCTGCACAGGACTTCTGCTGGTCAGTGCAGTGGCTGTTGCCGACGACGACACAGCGTC
TGTCGACGCATTCGTGCAGGCAGAAGCCAGTAAAGTGATGCAGGAAAATCATATCGCGGGCCTGTCGATTGCCGTCACTC
GCCAGGGCAAACAGCAGTTCTACACCTATGGCGTCGCGTCAAAAGCCACCGGCCAGCCAGTGACCCGCGATACGCTGTTT
GAACTCGGCTCGATCAGCAAGACCTTCACCGCCACCCTCGCTACCTGGGCGCAGGCCAATGGGCAGCTGTCGCTGACGCA
AAGCATCGACAGCTATATTCCGCAGTTGCAGGCCACGCGGCTGGGCAAGGTGCCAATTTTCCATCTGGGCACCCACACGG
CTGGCGGCTTCCCGCTTCAGGTGCCGGACAAAGTGCAGAACACCCGTCAGTTGATGGAATATTTCAAGGCCTGGCAGCCC
GAATATCTATCCGGCACCCATCGCACGTACGCCAACCCCAGTGTGGGCCTGCTCGGCATGGTTGCAGCGCGCAGCATGCA
GCTGCCGTATGAACAGGCCCTGCAGCAGCGGCTGTTTCCGGCGCTGGGTCTGAGTAACACCTATATCAACGTACCCGATG
AAAAACAGGCGCTGTATGCGCAGGGCTACAACAAACTCGACGAGCCGGTCAGGGTCAATCCAGGTCCGCTGGCGGCTGAA
GCCTACGGGGTGAAATCGAGCAGCAGCGACTTGCTACGCTTCATCGAAGCGAACATCGGCCTCGGTCAAAACGACGCCGC
GCTGCAAAAAGCCCTGCGCGATACCCGGACCGGCTATTTCAAGGTCGGCGGCATGACTCAGGACCTGATCTGGGAGCAGT
ATCCGCTGCCGGTTCGTCTGGAGACGCTGCTTGAGGGCAATGCCAGCGCCATGCTGAACACGGTCAAAGCCGAAATGATC
GAACCGCCGCAGGCAGCGCAATCTTCGGTCTGGGTCAACAAAACCGGATCAACCAACGGTTTCGGCGGCTATGTGGCGTT
CATTCCGGAGCAGCAGTTGGGGATTGCCATCCTCGCCAACAAAAACTACCCGAACGAGGAGCGGGTGAAACTGGCCTATC
GGATTCTGCAGAAAATGGGCTGCTGCTCAACGCCCTGA

Upstream 100 bases:

>100_bases
GCATATTACGCAAACCTTTGACGACCGACCACCACGGTGGGGCTTCCAGGAAAGCTCTCTGATGATCGGCCCATGCCTCA
AAACAACAAGGAGTAAACCG

Downstream 100 bases:

>100_bases
AAACAGCCCTGCCCCTTCGGCCGCTTCGATTTCAAGCAGCTTGCGCTTGCGCTCGACGCCCCAGCGGTAGCCCGACAACG
ATCCATCGCTGCGCACCACG

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQWNGALLCTGLLLVSAVAVADDDTASVDAFVQAEASKVMQENHIAGLSIAVTRQGKQQFYTYGVASKATGQPVTRDTLF
ELGSISKTFTATLATWAQANGQLSLTQSIDSYIPQLQATRLGKVPIFHLGTHTAGGFPLQVPDKVQNTRQLMEYFKAWQP
EYLSGTHRTYANPSVGLLGMVAARSMQLPYEQALQQRLFPALGLSNTYINVPDEKQALYAQGYNKLDEPVRVNPGPLAAE
AYGVKSSSSDLLRFIEANIGLGQNDAALQKALRDTRTGYFKVGGMTQDLIWEQYPLPVRLETLLEGNASAMLNTVKAEMI
EPPQAAQSSVWVNKTGSTNGFGGYVAFIPEQQLGIAILANKNYPNEERVKLAYRILQKMGCCSTP

Sequences:

>Translated_385_residues
MQWNGALLCTGLLLVSAVAVADDDTASVDAFVQAEASKVMQENHIAGLSIAVTRQGKQQFYTYGVASKATGQPVTRDTLF
ELGSISKTFTATLATWAQANGQLSLTQSIDSYIPQLQATRLGKVPIFHLGTHTAGGFPLQVPDKVQNTRQLMEYFKAWQP
EYLSGTHRTYANPSVGLLGMVAARSMQLPYEQALQQRLFPALGLSNTYINVPDEKQALYAQGYNKLDEPVRVNPGPLAAE
AYGVKSSSSDLLRFIEANIGLGQNDAALQKALRDTRTGYFKVGGMTQDLIWEQYPLPVRLETLLEGNASAMLNTVKAEMI
EPPQAAQSSVWVNKTGSTNGFGGYVAFIPEQQLGIAILANKNYPNEERVKLAYRILQKMGCCSTP
>Mature_385_residues
MQWNGALLCTGLLLVSAVAVADDDTASVDAFVQAEASKVMQENHIAGLSIAVTRQGKQQFYTYGVASKATGQPVTRDTLF
ELGSISKTFTATLATWAQANGQLSLTQSIDSYIPQLQATRLGKVPIFHLGTHTAGGFPLQVPDKVQNTRQLMEYFKAWQP
EYLSGTHRTYANPSVGLLGMVAARSMQLPYEQALQQRLFPALGLSNTYINVPDEKQALYAQGYNKLDEPVRVNPGPLAAE
AYGVKSSSSDLLRFIEANIGLGQNDAALQKALRDTRTGYFKVGGMTQDLIWEQYPLPVRLETLLEGNASAMLNTVKAEMI
EPPQAAQSSVWVNKTGSTNGFGGYVAFIPEQQLGIAILANKNYPNEERVKLAYRILQKMGCCSTP

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=374, Percent_Identity=41.7112299465241, Blast_Score=300, Evalue=8e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 41934; Mature: 41934

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00336 BETA_LACTAMASE_C

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQWNGALLCTGLLLVSAVAVADDDTASVDAFVQAEASKVMQENHIAGLSIAVTRQGKQQF
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
YTYGVASKATGQPVTRDTLFELGSISKTFTATLATWAQANGQLSLTQSIDSYIPQLQATR
EEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
LGKVPIFHLGTHTAGGFPLQVPDKVQNTRQLMEYFKAWQPEYLSGTHRTYANPSVGLLGM
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHH
VAARSMQLPYEQALQQRLFPALGLSNTYINVPDEKQALYAQGYNKLDEPVRVNPGPLAAE
HHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCHHCCCCEECCCCCCCHH
AYGVKSSSSDLLRFIEANIGLGQNDAALQKALRDTRTGYFKVGGMTQDLIWEQYPLPVRL
HCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCEEH
ETLLEGNASAMLNTVKAEMIEPPQAAQSSVWVNKTGSTNGFGGYVAFIPEQQLGIAILAN
HHHHCCCHHHHHHHHHHHHCCCCCHHCCCEEEECCCCCCCCCCEEEEECCCCCCEEEEEC
KNYPNEERVKLAYRILQKMGCCSTP
CCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQWNGALLCTGLLLVSAVAVADDDTASVDAFVQAEASKVMQENHIAGLSIAVTRQGKQQF
CCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
YTYGVASKATGQPVTRDTLFELGSISKTFTATLATWAQANGQLSLTQSIDSYIPQLQATR
EEECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHH
LGKVPIFHLGTHTAGGFPLQVPDKVQNTRQLMEYFKAWQPEYLSGTHRTYANPSVGLLGM
CCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHH
VAARSMQLPYEQALQQRLFPALGLSNTYINVPDEKQALYAQGYNKLDEPVRVNPGPLAAE
HHHHHCCCCHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHCCHHCCCCEECCCCCCCHH
AYGVKSSSSDLLRFIEANIGLGQNDAALQKALRDTRTGYFKVGGMTQDLIWEQYPLPVRL
HCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHCCCCCEEH
ETLLEGNASAMLNTVKAEMIEPPQAAQSSVWVNKTGSTNGFGGYVAFIPEQQLGIAILAN
HHHHCCCHHHHHHHHHHHHCCCCCHHCCCEEEECCCCCCCCCCEEEEECCCCCCEEEEEC
KNYPNEERVKLAYRILQKMGCCSTP
CCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA