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The map label for this gene is fhuA [H]

Identifier: 66046353

GI number: 66046353

Start: 3745488

End: 3747620

Strand: Reverse

Name: fhuA [H]

Synonym: Psyr_3124

Alternate gene names: 66046353

Gene position: 3747620-3745488 (Counterclockwise)

Preceding gene: 66046362

Following gene: 66046347

Centisome position: 61.5

GC content: 61.09

Gene sequence:

>2133_bases
ATGTCGATGCGTCGTACTCTCGTTTCACTTTGCGTTATCCAGGCTATCTCTCAAACTGCCTGGGCCGATCAGGTGCCTGG
CGTCCAGCCTGCCATGGAGCTGCAGAATATCGATATCCAGGGCGCCGCCAATGCCGAAACGGCACAAGGGCCGGTCGATG
GTTATCGGGCCACACGCTCCGCCAGCGCAACGCGTACCGATACCTCGTTGCACGAAACCCCGCAATCGGTCAGCGTCGTG
ACCCGCGAAGCGGTCGAGGACATCGGTTCCACACGTTTGCAGGATGCTCTCGACTACGCGGGTGGCGTCGGGCGAGCCAA
CAACTTCGGCGGCCAGGGGCTGACCACCTTTACGGTGCGCGGCTTTACCACCGGCGAGTTCTATCGCAACGGCTTCCCGA
TCAATCGTGGTTATCCGAACATGCCGGACGCCAACACCATCGAGCGTCTTGAGGTGCTGCGTGGTCCGGCCACCACGCTC
TATGGTCGCGGCGATCCGGGCGGCACCTTCAATGTGCTTTCCAAACAGCCGCTGGCCGAGCCTTCCGTGACGCTGGGCAG
TCAGCTCAATGATCAGGGCATGAAGCGCGGAACGCTGGATGCCTCCGGGCCACTGGATGACGAAGGCCGGTTTGCCTATC
GCCTGAATGTGGTGGGTGAGGGCGGCGATACGTTCCGTGACCACGTCGAAACCGAGCGCTATGGCGTGGCGCCAGTATTG
AGCTGGCAGGTCAACGACGCCACGCGCATCACCTTCGAAGGCGACTTCATGCGCAACAACGCGCCGCTGGATCGCGGTTT
GACGCGGTATGCCAACCAGACGGGCACCGCTTCCCGCGACACGTTCTTCGGCGAGAAGAGTGTGGGCAAGCTGCATAACG
ATAACAACATGGCACAGCTGCGCTTCGAGCATGACCTCAACCCGGACTGGACGCTGGGCGGTGGCTTACAGATCCTTGAC
GGCTCCCTGCAGGGCGATGCCATCGAGGCCAACGGGCTGGCGGCGGACGGTCGCACGCTCGGGCGCAACTTCAACTATCG
CAAGCTGGAATGGACCGATCGCGATGTGCAGCTGAATCTGACCGGGCATTTTTCAGCGGGCGGTTTCGAGCACACGCTGC
TGACCGGTGTCGAGTACGAAGATTATGACTACAAGTCGATCATTCAACGTTCCAGCGGTGCAGTAGCTGCCTACCCGATC
GACCTCTTCAATCCGGTCTACGGCCAGGCTCGTCCGGCACTGACCCGAACGACCACCCATGACAAGGAAAACCTCAAGAC
CTGGGCTGCCTTCGTACAGGACCAGGTGGCCCTGACCGAGCGCCTGAAGCTGCTGGGCGGTGTGCGTCTGGAGCGTTTCG
AACATGATTACGATTCTTTCCTGCCCGGCACCAGCAGCTGGACTGCCAGCGATAACGCGGTCACACCGCGCCTCGGCCTG
AGCTACGACCTGACCGACGACCTTGCCGTCTACGCCACCACCGCTCGCTCGTTCAAGCCCAACAGCGGTGCCAGCCGACT
GGGTGGCGGGTTCAAGCCGGAGGAGGGCAAGTCCTATGAAGTCGGAACCAAGTGGGAAGCGCTGGACGGGCAGCTGAGTG
TCGACACGGCGATCTATCAGATCGAAAAGCGTAACGTGCTGACCACCGATCCGGTCGATTCAACGTTCAGTGTGGCGGCG
GGCGAGGTGCGCAGTCGCGGCCTGGACCTGAACGTGGTCGGCAACCTGACTCCGCAATGGCGGGTAATGGGCAGCTACGC
CTACGTGGACGCCGAGGTCACCAAGGACAACACGCTACGCTCCGGTACACGGTTGATGAACATTCCCGAGCAAACGTTCA
GCCTGCTCAACGTCTACGAGTTTCAGGACGGCGCCCTGCGTGGTCTGGGCCTGGGCGGCGGCGGTCGCTATGTCGACCAG
CGCGCCGGGCGGACAGCCAACACCTCTTTCTCGATGGACAGCTATACAGTGTTTGACCTGTTGGCCTATTACAAGGTCAA
CCCGCACGTGAAGCTCAATCTGGACCTGAAGAATGTGTTCGACACAGACTATGAGGAAGGCTCTTTCGGCAATGTCTATG
CCTATCCGGGGGCTCCACGGACAGTGCAGGTGGGGATTGCCTATACGTTGTGA

Upstream 100 bases:

>100_bases
TATTTTTTGGGAATTTGTATCAGGCGTTAATACGAATCTGTACTATTCGCAAAAAAATCCTGCCAGGTCCCAAGAGGCCT
GGTTTCTTGCCAAGGGCTGT

Downstream 100 bases:

>100_bases
TGCCGTGTGCCGGTATCGGGTTCTGATGGAGAAAGCTTGACCCTTTCAAGGGCAGGTTCAGCAGCGTGTGTCATGGGCAC
CGGCCCTTGCGCACACGCGG

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MSMRRTLVSLCVIQAISQTAWADQVPGVQPAMELQNIDIQGAANAETAQGPVDGYRATRSASATRTDTSLHETPQSVSVV
TREAVEDIGSTRLQDALDYAGGVGRANNFGGQGLTTFTVRGFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATTL
YGRGDPGGTFNVLSKQPLAEPSVTLGSQLNDQGMKRGTLDASGPLDDEGRFAYRLNVVGEGGDTFRDHVETERYGVAPVL
SWQVNDATRITFEGDFMRNNAPLDRGLTRYANQTGTASRDTFFGEKSVGKLHNDNNMAQLRFEHDLNPDWTLGGGLQILD
GSLQGDAIEANGLAADGRTLGRNFNYRKLEWTDRDVQLNLTGHFSAGGFEHTLLTGVEYEDYDYKSIIQRSSGAVAAYPI
DLFNPVYGQARPALTRTTTHDKENLKTWAAFVQDQVALTERLKLLGGVRLERFEHDYDSFLPGTSSWTASDNAVTPRLGL
SYDLTDDLAVYATTARSFKPNSGASRLGGGFKPEEGKSYEVGTKWEALDGQLSVDTAIYQIEKRNVLTTDPVDSTFSVAA
GEVRSRGLDLNVVGNLTPQWRVMGSYAYVDAEVTKDNTLRSGTRLMNIPEQTFSLLNVYEFQDGALRGLGLGGGGRYVDQ
RAGRTANTSFSMDSYTVFDLLAYYKVNPHVKLNLDLKNVFDTDYEEGSFGNVYAYPGAPRTVQVGIAYTL

Sequences:

>Translated_710_residues
MSMRRTLVSLCVIQAISQTAWADQVPGVQPAMELQNIDIQGAANAETAQGPVDGYRATRSASATRTDTSLHETPQSVSVV
TREAVEDIGSTRLQDALDYAGGVGRANNFGGQGLTTFTVRGFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATTL
YGRGDPGGTFNVLSKQPLAEPSVTLGSQLNDQGMKRGTLDASGPLDDEGRFAYRLNVVGEGGDTFRDHVETERYGVAPVL
SWQVNDATRITFEGDFMRNNAPLDRGLTRYANQTGTASRDTFFGEKSVGKLHNDNNMAQLRFEHDLNPDWTLGGGLQILD
GSLQGDAIEANGLAADGRTLGRNFNYRKLEWTDRDVQLNLTGHFSAGGFEHTLLTGVEYEDYDYKSIIQRSSGAVAAYPI
DLFNPVYGQARPALTRTTTHDKENLKTWAAFVQDQVALTERLKLLGGVRLERFEHDYDSFLPGTSSWTASDNAVTPRLGL
SYDLTDDLAVYATTARSFKPNSGASRLGGGFKPEEGKSYEVGTKWEALDGQLSVDTAIYQIEKRNVLTTDPVDSTFSVAA
GEVRSRGLDLNVVGNLTPQWRVMGSYAYVDAEVTKDNTLRSGTRLMNIPEQTFSLLNVYEFQDGALRGLGLGGGGRYVDQ
RAGRTANTSFSMDSYTVFDLLAYYKVNPHVKLNLDLKNVFDTDYEEGSFGNVYAYPGAPRTVQVGIAYTL
>Mature_709_residues
SMRRTLVSLCVIQAISQTAWADQVPGVQPAMELQNIDIQGAANAETAQGPVDGYRATRSASATRTDTSLHETPQSVSVVT
REAVEDIGSTRLQDALDYAGGVGRANNFGGQGLTTFTVRGFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATTLY
GRGDPGGTFNVLSKQPLAEPSVTLGSQLNDQGMKRGTLDASGPLDDEGRFAYRLNVVGEGGDTFRDHVETERYGVAPVLS
WQVNDATRITFEGDFMRNNAPLDRGLTRYANQTGTASRDTFFGEKSVGKLHNDNNMAQLRFEHDLNPDWTLGGGLQILDG
SLQGDAIEANGLAADGRTLGRNFNYRKLEWTDRDVQLNLTGHFSAGGFEHTLLTGVEYEDYDYKSIIQRSSGAVAAYPID
LFNPVYGQARPALTRTTTHDKENLKTWAAFVQDQVALTERLKLLGGVRLERFEHDYDSFLPGTSSWTASDNAVTPRLGLS
YDLTDDLAVYATTARSFKPNSGASRLGGGFKPEEGKSYEVGTKWEALDGQLSVDTAIYQIEKRNVLTTDPVDSTFSVAAG
EVRSRGLDLNVVGNLTPQWRVMGSYAYVDAEVTKDNTLRSGTRLMNIPEQTFSLLNVYEFQDGALRGLGLGGGGRYVDQR
AGRTANTSFSMDSYTVFDLLAYYKVNPHVKLNLDLKNVFDTDYEEGSFGNVYAYPGAPRTVQVGIAYTL

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=745, Percent_Identity=29.6644295302013, Blast_Score=259, Evalue=5e-70,
Organism=Escherichia coli, GI1787024, Length=764, Percent_Identity=27.2251308900524, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787344, Length=763, Percent_Identity=22.2804718217562, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1787723, Length=686, Percent_Identity=24.198250728863, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790743, Length=157, Percent_Identity=31.2101910828025, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77674; Mature: 77543

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMRRTLVSLCVIQAISQTAWADQVPGVQPAMELQNIDIQGAANAETAQGPVDGYRATRS
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHCC
ASATRTDTSLHETPQSVSVVTREAVEDIGSTRLQDALDYAGGVGRANNFGGQGLTTFTVR
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
GFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATTLYGRGDPGGTFNVLSKQPLAE
CCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCC
PSVTLGSQLNDQGMKRGTLDASGPLDDEGRFAYRLNVVGEGGDTFRDHVETERYGVAPVL
CCCHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCEEE
SWQVNDATRITFEGDFMRNNAPLDRGLTRYANQTGTASRDTFFGEKSVGKLHNDNNMAQL
EEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
RFEHDLNPDWTLGGGLQILDGSLQGDAIEANGLAADGRTLGRNFNYRKLEWTDRDVQLNL
EEECCCCCCEEECCCEEEEECCCCCCEEECCCCCCCCHHHCCCCCEEEEEECCCEEEEEE
TGHFSAGGFEHTLLTGVEYEDYDYKSIIQRSSGAVAAYPIDLFNPVYGQARPALTRTTTH
EEEECCCCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCEEECCCC
DKENLKTWAAFVQDQVALTERLKLLGGVRLERFEHDYDSFLPGTSSWTASDNAVTPRLGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCC
SYDLTDDLAVYATTARSFKPNSGASRLGGGFKPEEGKSYEVGTKWEALDGQLSVDTAIYQ
EECCCCCEEEEEEECCCCCCCCCHHHHCCCCCCCCCCCEECCCCEECCCCCEEECCEEEE
IEKRNVLTTDPVDSTFSVAAGEVRSRGLDLNVVGNLTPQWRVMGSYAYVDAEVTKDNTLR
EECCCEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEEEEEECCCCCHH
SGTRLMNIPEQTFSLLNVYEFQDGALRGLGLGGGGRYVDQRAGRTANTSFSMDSYTVFDL
CCCEEECCCHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCHHHHHH
LAYYKVNPHVKLNLDLKNVFDTDYEEGSFGNVYAYPGAPRTVQVGIAYTL
HHHEECCCCEEEEEEHHHHCCCCCCCCCCCCEEECCCCCCEEEEEEEEEC
>Mature Secondary Structure 
SMRRTLVSLCVIQAISQTAWADQVPGVQPAMELQNIDIQGAANAETAQGPVDGYRATRS
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCHHHHHCC
ASATRTDTSLHETPQSVSVVTREAVEDIGSTRLQDALDYAGGVGRANNFGGQGLTTFTVR
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEE
GFTTGEFYRNGFPINRGYPNMPDANTIERLEVLRGPATTLYGRGDPGGTFNVLSKQPLAE
CCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCCCC
PSVTLGSQLNDQGMKRGTLDASGPLDDEGRFAYRLNVVGEGGDTFRDHVETERYGVAPVL
CCCHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCEEE
SWQVNDATRITFEGDFMRNNAPLDRGLTRYANQTGTASRDTFFGEKSVGKLHNDNNMAQL
EEEECCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEE
RFEHDLNPDWTLGGGLQILDGSLQGDAIEANGLAADGRTLGRNFNYRKLEWTDRDVQLNL
EEECCCCCCEEECCCEEEEECCCCCCEEECCCCCCCCHHHCCCCCEEEEEECCCEEEEEE
TGHFSAGGFEHTLLTGVEYEDYDYKSIIQRSSGAVAAYPIDLFNPVYGQARPALTRTTTH
EEEECCCCCCEEEEECCCCCCCCHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCEEECCCC
DKENLKTWAAFVQDQVALTERLKLLGGVRLERFEHDYDSFLPGTSSWTASDNAVTPRLGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCC
SYDLTDDLAVYATTARSFKPNSGASRLGGGFKPEEGKSYEVGTKWEALDGQLSVDTAIYQ
EECCCCCEEEEEEECCCCCCCCCHHHHCCCCCCCCCCCEECCCCEECCCCCEEECCEEEE
IEKRNVLTTDPVDSTFSVAAGEVRSRGLDLNVVGNLTPQWRVMGSYAYVDAEVTKDNTLR
EECCCEEECCCCCCCHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEEEEEECCCCCHH
SGTRLMNIPEQTFSLLNVYEFQDGALRGLGLGGGGRYVDQRAGRTANTSFSMDSYTVFDL
CCCEEECCCHHHHHHHHHEECCCCCEEEEEECCCCCHHHHHCCCCCCCCCCCCCHHHHHH
LAYYKVNPHVKLNLDLKNVFDTDYEEGSFGNVYAYPGAPRTVQVGIAYTL
HHHEECCCCEEEEEEHHHHCCCCCCCCCCCCEEECCCCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]