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The map label for this gene is uxuR [H]

Identifier: 66046347

GI number: 66046347

Start: 3738093

End: 3738806

Strand: Reverse

Name: uxuR [H]

Synonym: Psyr_3118

Alternate gene names: 66046347

Gene position: 3738806-3738093 (Counterclockwise)

Preceding gene: 66046353

Following gene: 66046345

Centisome position: 61.36

GC content: 62.89

Gene sequence:

>714_bases
ATGCAAGAGCCTGCCAGCACAGCGCCCAAACGCCGTCAGCACAACCTGGCCACCGATCTGGTCACCGAACTGAGCCAGCG
CATCCTGCTCGGCAAGATCGCACCCGGTCAGAAGCTGCCGTCCGAGAACCAGATCGTCCGCGAGCACGGCGTTAGCCGTA
CCGTGGTACGTGAAGCGATTTCCAAATTGCAGGCGTCCGGGCTGGTGGTGACCCATCACGGCATCGGCACCTTCGTGCTC
GAGCGCAGTGATCAGACGGGGCTGCGCCTCAAGGTCGAGACCGTTTCCAGAGTGCGCGATATCATCGAACTGCGCATCGG
CCTGGAAACCCAGGCCGTGGCGCTGGCGGCTGTGCGCCGTACCGATGAGCAACTGGCGGCCATGCGTCAGGCGCTGGATG
ATTATCAGGACCTGCTGGCCAACGACGACAGCTGCGTCGAGGCTGACAAGCGCTTTCACATGCTGATCGCCGAAGCCACC
GGCAACCCGTATTTTCTGGAGATCATGCAACACCTGGGCAGTGCGGTCATTCCGCGCAGCCGCATTGCATCGAGCGAGCG
GGCAGGTAACAACCTTGCGCATCAGGGCTACCTGGCCAACCTGGAACACGAAGCGCTGCTCAGCGCCATTCGCCGCAAGG
ACCCGGATGCCGCGCGTGCAGCGATGTGGACGCATCTGAGCAACAGCCGAGAGCGGCTGGTTCCACTGGAGTAG

Upstream 100 bases:

>100_bases
CGGGCTGTCAAACCCGGCTTCCGGCCGCTCTCAGTCCGGTATTCGCGCTGCCATGGCCGTGATACGGCAGCATAAACAGA
CAAGTCAGGATTCATTCACC

Downstream 100 bases:

>100_bases
GCGCGAACGTGTTTGCTCCCACAAGAGCCCTCCATACTCGAGCGTACGGCAAAAATGTAGGAGCGAACCGGGCGACGCTT
CGCTTGTTCGCGAAAGGGGC

Product: transcriptional regulator GntR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MQEPASTAPKRRQHNLATDLVTELSQRILLGKIAPGQKLPSENQIVREHGVSRTVVREAISKLQASGLVVTHHGIGTFVL
ERSDQTGLRLKVETVSRVRDIIELRIGLETQAVALAAVRRTDEQLAAMRQALDDYQDLLANDDSCVEADKRFHMLIAEAT
GNPYFLEIMQHLGSAVIPRSRIASSERAGNNLAHQGYLANLEHEALLSAIRRKDPDAARAAMWTHLSNSRERLVPLE

Sequences:

>Translated_237_residues
MQEPASTAPKRRQHNLATDLVTELSQRILLGKIAPGQKLPSENQIVREHGVSRTVVREAISKLQASGLVVTHHGIGTFVL
ERSDQTGLRLKVETVSRVRDIIELRIGLETQAVALAAVRRTDEQLAAMRQALDDYQDLLANDDSCVEADKRFHMLIAEAT
GNPYFLEIMQHLGSAVIPRSRIASSERAGNNLAHQGYLANLEHEALLSAIRRKDPDAARAAMWTHLSNSRERLVPLE
>Mature_237_residues
MQEPASTAPKRRQHNLATDLVTELSQRILLGKIAPGQKLPSENQIVREHGVSRTVVREAISKLQASGLVVTHHGIGTFVL
ERSDQTGLRLKVETVSRVRDIIELRIGLETQAVALAAVRRTDEQLAAMRQALDDYQDLLANDDSCVEADKRFHMLIAEAT
GNPYFLEIMQHLGSAVIPRSRIASSERAGNNLAHQGYLANLEHEALLSAIRRKDPDAARAAMWTHLSNSRERLVPLE

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=206, Percent_Identity=33.9805825242718, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI48994961, Length=229, Percent_Identity=32.3144104803493, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1789621, Length=219, Percent_Identity=31.5068493150685, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI48994955, Length=236, Percent_Identity=30.5084745762712, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1790032, Length=201, Percent_Identity=31.3432835820896, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI87082208, Length=247, Percent_Identity=28.7449392712551, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786303, Length=125, Percent_Identity=37.6, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26299; Mature: 26299

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEPASTAPKRRQHNLATDLVTELSQRILLGKIAPGQKLPSENQIVREHGVSRTVVREAI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHH
SKLQASGLVVTHHGIGTFVLERSDQTGLRLKVETVSRVRDIIELRIGLETQAVALAAVRR
HHHHHCCEEEEECCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TDEQLAAMRQALDDYQDLLANDDSCVEADKRFHMLIAEATGNPYFLEIMQHLGSAVIPRS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCHH
RIASSERAGNNLAHQGYLANLEHEALLSAIRRKDPDAARAAMWTHLSNSRERLVPLE
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MQEPASTAPKRRQHNLATDLVTELSQRILLGKIAPGQKLPSENQIVREHGVSRTVVREAI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHH
SKLQASGLVVTHHGIGTFVLERSDQTGLRLKVETVSRVRDIIELRIGLETQAVALAAVRR
HHHHHCCEEEEECCCEEEEEECCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TDEQLAAMRQALDDYQDLLANDDSCVEADKRFHMLIAEATGNPYFLEIMQHLGSAVIPRS
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHCCCHH
RIASSERAGNNLAHQGYLANLEHEALLSAIRRKDPDAARAAMWTHLSNSRERLVPLE
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]