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The map label for this gene is mhpT [H]

Identifier: 66045967

GI number: 66045967

Start: 3314762

End: 3315982

Strand: Direct

Name: mhpT [H]

Synonym: Psyr_2731

Alternate gene names: 66045967

Gene position: 3314762-3315982 (Clockwise)

Preceding gene: 66045965

Following gene: 66045971

Centisome position: 54.4

GC content: 62.57

Gene sequence:

>1221_bases
ATGAACAGTCCGTTACGTCGATCGACGCTGACCATTGTCTTGTGTTTTATCGTTGCGCTCATCGAGGGCTTCGACCTGCA
GGCTGCGGGAACGGCCGCCGCCGGATTGCGCCAGACCTTCGCCCTCGATCCGAAAATGATGGGCTGGGTATTCAGCGCCG
GGATCATCGGGCTGCTGCCTGGCGCGTTCTTTGGCGGATGGATCGCCGATCGCATCGGCCGCAAGAGGATTCTGGTCAGC
GCAGTGCTGCTGTTCGGGGTCTTTTCACTGAGCACTGCTTATGTCGAGAGCTTTTCCGGACTGTTGCTGGTGCGCTTCAT
GACCGGCCTGGGTCTGGGGGCCGCGCTGCCCAATCTGATCGCCTTGTGCGCAGAAGCCGTCAGCGAACGTCACCGCGGGC
TGGCCATCAGCGTCATGTACGCCGGTGTTCCATTGGGTGGTGCCCTCGCGGCGGTTGTGGCCATGTTCACCAGCGAGCAC
TGGCAAACCACGTTCATCATCGGCGGTCTGGTGCCGCTGCTGGTAGCTCCGCTGATGATCCTGTTACTGCCCGAGTCCAG
CGCTTTCAAACAGCAGACCACTGCTGACAGCGTTCGGTATTCAAGCGCCACTGCGTTGTTCGGCGAAGGCCGGGCGCGCA
CGACACTGGCTTTATGGCTTGGCTACTTCTTTACCCTGACCGTGATGTACATGCTGCTCAACTGGCTGCCTTCACTGCTG
ATCGGTCAGGGTTTCAGCAAACCGCAGGCAGGCATGGTGCAGATGCTGTTCAATATCGGCGGCGCGCTGGGCTCGTTGCT
GGGCGGGTTGTTGCTCGATCGCTGCAATGGCATCAAGGTCGTGCTGTTCGTCTACGCCGGTTTGCTCGCGGCGCTGGCAG
GCGTGGGTCTGTCGGTCGGTATCGTACCGATGGCCGTTGCCGGGTTTGCAGCCGGGGTGTTTGTCATCGCCGCGCAGTTG
GTGCTGTATGCACTGGCCCCGCCCTCCTACCCGACCTCGGTACGTGCCACCGGTGTGGGTGCAGCAGTGGCCATCGGCCG
TCTCGGTTCGGTCGCCGGTCCCCTGGCAGCCGGACAACTGCTGGGCGCTGGCGCCGGAACCGCCGGCGTACTGCTGGCTA
CCTCGCCAGGCCTGGTGATTGCCGCACTGGCAGCGATCACAGTGCTGTCCAGGTCAGTCGCCATCGAGAAGCGTGAGCTC
AAGGCTGCAGAGTCGAGCTGA

Upstream 100 bases:

>100_bases
TTAGTTATTTTTGTTACCTTGATAAATACCTGTGACAACGCCTCGATTGGCGCTGGGGAACAGGCTTTTCTCCACAACAA
AAACAACAATGAGGCTTGCC

Downstream 100 bases:

>100_bases
TCAAGGCCCTTTTCGCCAACAAGCGAAGCTTCGCCCGGTCCACTCCCACGGCCTCCGGCCAGAATCAAAAGCGGATTTAT
GTATAACAATGAGCAATCCG

Product: putative 3-hydroxyphenylpropionic transporter MhpT

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MNSPLRRSTLTIVLCFIVALIEGFDLQAAGTAAAGLRQTFALDPKMMGWVFSAGIIGLLPGAFFGGWIADRIGRKRILVS
AVLLFGVFSLSTAYVESFSGLLLVRFMTGLGLGAALPNLIALCAEAVSERHRGLAISVMYAGVPLGGALAAVVAMFTSEH
WQTTFIIGGLVPLLVAPLMILLLPESSAFKQQTTADSVRYSSATALFGEGRARTTLALWLGYFFTLTVMYMLLNWLPSLL
IGQGFSKPQAGMVQMLFNIGGALGSLLGGLLLDRCNGIKVVLFVYAGLLAALAGVGLSVGIVPMAVAGFAAGVFVIAAQL
VLYALAPPSYPTSVRATGVGAAVAIGRLGSVAGPLAAGQLLGAGAGTAGVLLATSPGLVIAALAAITVLSRSVAIEKREL
KAAESS

Sequences:

>Translated_406_residues
MNSPLRRSTLTIVLCFIVALIEGFDLQAAGTAAAGLRQTFALDPKMMGWVFSAGIIGLLPGAFFGGWIADRIGRKRILVS
AVLLFGVFSLSTAYVESFSGLLLVRFMTGLGLGAALPNLIALCAEAVSERHRGLAISVMYAGVPLGGALAAVVAMFTSEH
WQTTFIIGGLVPLLVAPLMILLLPESSAFKQQTTADSVRYSSATALFGEGRARTTLALWLGYFFTLTVMYMLLNWLPSLL
IGQGFSKPQAGMVQMLFNIGGALGSLLGGLLLDRCNGIKVVLFVYAGLLAALAGVGLSVGIVPMAVAGFAAGVFVIAAQL
VLYALAPPSYPTSVRATGVGAAVAIGRLGSVAGPLAAGQLLGAGAGTAGVLLATSPGLVIAALAAITVLSRSVAIEKREL
KAAESS
>Mature_406_residues
MNSPLRRSTLTIVLCFIVALIEGFDLQAAGTAAAGLRQTFALDPKMMGWVFSAGIIGLLPGAFFGGWIADRIGRKRILVS
AVLLFGVFSLSTAYVESFSGLLLVRFMTGLGLGAALPNLIALCAEAVSERHRGLAISVMYAGVPLGGALAAVVAMFTSEH
WQTTFIIGGLVPLLVAPLMILLLPESSAFKQQTTADSVRYSSATALFGEGRARTTLALWLGYFFTLTVMYMLLNWLPSLL
IGQGFSKPQAGMVQMLFNIGGALGSLLGGLLLDRCNGIKVVLFVYAGLLAALAGVGLSVGIVPMAVAGFAAGVFVIAAQL
VLYALAPPSYPTSVRATGVGAAVAIGRLGSVAGPLAAGQLLGAGAGTAGVLLATSPGLVIAALAAITVLSRSVAIEKREL
KAAESS

Specific function: Could be a transporter for 3-phenylpropionate (hydrocinnamic acid) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI73695465, Length=157, Percent_Identity=26.7515923566879, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081723, Length=389, Percent_Identity=52.6992287917738, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1789152, Length=430, Percent_Identity=23.0232558139535, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786229, Length=396, Percent_Identity=23.989898989899, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788074, Length=369, Percent_Identity=26.0162601626016, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640198, Length=229, Percent_Identity=25.3275109170306, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640196, Length=229, Percent_Identity=25.3275109170306, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640200, Length=229, Percent_Identity=25.3275109170306, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004746
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41676; Mature: 41676

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSPLRRSTLTIVLCFIVALIEGFDLQAAGTAAAGLRQTFALDPKMMGWVFSAGIIGLLP
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GAFFGGWIADRIGRKRILVSAVLLFGVFSLSTAYVESFSGLLLVRFMTGLGLGAALPNLI
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ALCAEAVSERHRGLAISVMYAGVPLGGALAAVVAMFTSEHWQTTFIIGGLVPLLVAPLMI
HHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LLLPESSAFKQQTTADSVRYSSATALFGEGRARTTLALWLGYFFTLTVMYMLLNWLPSLL
HHCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGQGFSKPQAGMVQMLFNIGGALGSLLGGLLLDRCNGIKVVLFVYAGLLAALAGVGLSVG
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHH
IVPMAVAGFAAGVFVIAAQLVLYALAPPSYPTSVRATGVGAAVAIGRLGSVAGPLAAGQL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHCHHHHHHH
LGAGAGTAGVLLATSPGLVIAALAAITVLSRSVAIEKRELKAAESS
HCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNSPLRRSTLTIVLCFIVALIEGFDLQAAGTAAAGLRQTFALDPKMMGWVFSAGIIGLLP
CCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
GAFFGGWIADRIGRKRILVSAVLLFGVFSLSTAYVESFSGLLLVRFMTGLGLGAALPNLI
HHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
ALCAEAVSERHRGLAISVMYAGVPLGGALAAVVAMFTSEHWQTTFIIGGLVPLLVAPLMI
HHHHHHHHHHHCCEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LLLPESSAFKQQTTADSVRYSSATALFGEGRARTTLALWLGYFFTLTVMYMLLNWLPSLL
HHCCCCHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGQGFSKPQAGMVQMLFNIGGALGSLLGGLLLDRCNGIKVVLFVYAGLLAALAGVGLSVG
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHH
IVPMAVAGFAAGVFVIAAQLVLYALAPPSYPTSVRATGVGAAVAIGRLGSVAGPLAAGQL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCHHHHHHHHHHHHHCHHHHHHH
LGAGAGTAGVLLATSPGLVIAALAAITVLSRSVAIEKRELKAAESS
HCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]