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The map label for this gene is xylR [H]

Identifier: 66045971

GI number: 66045971

Start: 3320139

End: 3321902

Strand: Direct

Name: xylR [H]

Synonym: Psyr_2735

Alternate gene names: 66045971

Gene position: 3320139-3321902 (Clockwise)

Preceding gene: 66045967

Following gene: 66045976

Centisome position: 54.48

GC content: 62.41

Gene sequence:

>1764_bases
ATGAACAACCCTCACTGCGAGCTGCCCGATCACAGCGTCCCCACCGAGCATTTCTCGCCTCGCGGCGACAGCAGTCAGAC
GCACGCAGGCGACTCGCCAACCGCTGAGGAATTGACCAGTTGCCTGTTCTTCTCGCCCGATGATGGGCGCATCTGGCTTA
ACGACCAACGCATGATGCTGCTGCATACTTCATCGTTCGGCACCCTGCGCCGCGAAATCATCGAACGGCTGGGCCTGGAA
CAGGCACGCGGGATGTTCACCCGTGCCGGGTATCTGTCTGGCGCGCGGGACGCCCGATTGATTCGCGAACGCTGGCCACA
GGCTGACGCCTCGTCGGCGTTTCGTGCCGGTACGCACTTGCATACCCTGGAAGGCATGACCAAGGTCGAGCCGCTGCACT
TCAAATTCGACGCCGAGTCGGGGTTCTACGAGGGGGAGTTTCTCTGGCATCACTCGTGCGAAGCCGACGAACATGTTGCA
GCGTATGGCATCGGCCAGGACCCGGTGTGCTGGACCGAAATCGGTTACGCCACGGGCTTTGTCAGCGGCCTGTTCGGGCA
GATGGTGGTTTTCCGCGAGGTGGAATGCCGGGGCATGGGGCATGCGAACTGCCGTGTGGTCGGCAAGACCTCGGAACAAT
GGGGCGATGTCGAACGCGACCTGAGCTACCTGAGAGCGGTCAACTCACCTGCGCCAGTACACAGCGTCCCGACGCCAGCG
GCGAGCTATGAGGCAAGCCCGCCGACCGGCACCGACCAGCCGCTGGTCGGCGCAAGCGCTGCCTTCAATGCGGCCACCCA
GGCGTTGCAACGGGTGGCGATGACCCCGGCAACCGTATTGATCAGCGGCGAGTCCGGAGTCGGCAAGGAAATGTTCGCCC
GCCAGTTGCATCAGCTCAGCCGCCACCGCGAAGGCCCGTTCGTTGCACTCAACTGCGCAGCCATTCCCGACAACCTTATC
GAGGCCGAGCTGTTCGGTGTGGAGCGAGGGGCTTATACCGGGGCAACGCATTCCAGAGCCGGGCGTTTCGAGCGCGCCAA
CGGTGGCACGCTGTTTCTGGATGAAATCACCTCTCTGAGCCTTGCCGGGCAAAGCAAGCTGCTGCGCGCTTTGCAGGAAC
GCGAGATCGAGCGCGTCGGCGGGGTGCACGGCATCAAGGTCAACGTTCGAGTGGTGGCGGCGACCAATGTCGACCTGCGC
AAGGCGGTGGCCGAGGGCGATTTCCGCGAAGACCTGTTCTATCGCCTGAATGTCTACCCGATCGCCCTGCCGCCATTGCG
CGAGCGCCGCGATGACATTCCGCTGCTGATCAATTTCTTTCTCGGGCGCTTCTGTCAGGAGTACGGCAGGACGCCGGCCG
GATTGACCATGCGCGCGCTGAAGACCCTGCTGGGTTATGACTTTGCCGGGAATGTGCGCGAATTGCAGAACCTGATCGAG
CGCGGCCTGATTGCCAGTGATGAAGGCCAGGCCATAGATCTGGTGCATATTTTCCGCAACGAATCGTTACCACGGGACAC
CTACTCGCTGAATCACCATGGAGCACTGCGTCAGGCATCGACTGCGGGCGCACAGCAGGTACCTGCTACCTCGCTGCTGG
GTACCCTTAATCAGCCGGATAAGGCGTTCTCCATCGACGAGCTTGAACAGCGCCTTATCCAGGAGGCGCTGGACAAGAGC
GAAGGCAACCTGGCGGCCGCCTCGCGCTTGCTGGGCCTGAGCCGCGCCCAGTTTGCCTACCGCCTGAAAAAGCGTCAGCC
CTGA

Upstream 100 bases:

>100_bases
TCAAACTCTACGCGGACACGCTTGTTCATTTGATGAAGTTATGTTTATTGATCAAGCCTCGATTTGATCATTTCGACCAT
TGCCCGGCCGAGGTACACCC

Downstream 100 bases:

>100_bases
ACAGCCTGATTCGGTTTCACGCGCAGCCAGTCCGGCTGCGCGTGACACCTCAGAGTGGCAAGGCGCTGACCACACGCAGA
GCCAGCCCTTCGTAGGCATC

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: 67 kDa protein [H]

Number of amino acids: Translated: 587; Mature: 587

Protein sequence:

>587_residues
MNNPHCELPDHSVPTEHFSPRGDSSQTHAGDSPTAEELTSCLFFSPDDGRIWLNDQRMMLLHTSSFGTLRREIIERLGLE
QARGMFTRAGYLSGARDARLIRERWPQADASSAFRAGTHLHTLEGMTKVEPLHFKFDAESGFYEGEFLWHHSCEADEHVA
AYGIGQDPVCWTEIGYATGFVSGLFGQMVVFREVECRGMGHANCRVVGKTSEQWGDVERDLSYLRAVNSPAPVHSVPTPA
ASYEASPPTGTDQPLVGASAAFNAATQALQRVAMTPATVLISGESGVGKEMFARQLHQLSRHREGPFVALNCAAIPDNLI
EAELFGVERGAYTGATHSRAGRFERANGGTLFLDEITSLSLAGQSKLLRALQEREIERVGGVHGIKVNVRVVAATNVDLR
KAVAEGDFREDLFYRLNVYPIALPPLRERRDDIPLLINFFLGRFCQEYGRTPAGLTMRALKTLLGYDFAGNVRELQNLIE
RGLIASDEGQAIDLVHIFRNESLPRDTYSLNHHGALRQASTAGAQQVPATSLLGTLNQPDKAFSIDELEQRLIQEALDKS
EGNLAAASRLLGLSRAQFAYRLKKRQP

Sequences:

>Translated_587_residues
MNNPHCELPDHSVPTEHFSPRGDSSQTHAGDSPTAEELTSCLFFSPDDGRIWLNDQRMMLLHTSSFGTLRREIIERLGLE
QARGMFTRAGYLSGARDARLIRERWPQADASSAFRAGTHLHTLEGMTKVEPLHFKFDAESGFYEGEFLWHHSCEADEHVA
AYGIGQDPVCWTEIGYATGFVSGLFGQMVVFREVECRGMGHANCRVVGKTSEQWGDVERDLSYLRAVNSPAPVHSVPTPA
ASYEASPPTGTDQPLVGASAAFNAATQALQRVAMTPATVLISGESGVGKEMFARQLHQLSRHREGPFVALNCAAIPDNLI
EAELFGVERGAYTGATHSRAGRFERANGGTLFLDEITSLSLAGQSKLLRALQEREIERVGGVHGIKVNVRVVAATNVDLR
KAVAEGDFREDLFYRLNVYPIALPPLRERRDDIPLLINFFLGRFCQEYGRTPAGLTMRALKTLLGYDFAGNVRELQNLIE
RGLIASDEGQAIDLVHIFRNESLPRDTYSLNHHGALRQASTAGAQQVPATSLLGTLNQPDKAFSIDELEQRLIQEALDKS
EGNLAAASRLLGLSRAQFAYRLKKRQP
>Mature_587_residues
MNNPHCELPDHSVPTEHFSPRGDSSQTHAGDSPTAEELTSCLFFSPDDGRIWLNDQRMMLLHTSSFGTLRREIIERLGLE
QARGMFTRAGYLSGARDARLIRERWPQADASSAFRAGTHLHTLEGMTKVEPLHFKFDAESGFYEGEFLWHHSCEADEHVA
AYGIGQDPVCWTEIGYATGFVSGLFGQMVVFREVECRGMGHANCRVVGKTSEQWGDVERDLSYLRAVNSPAPVHSVPTPA
ASYEASPPTGTDQPLVGASAAFNAATQALQRVAMTPATVLISGESGVGKEMFARQLHQLSRHREGPFVALNCAAIPDNLI
EAELFGVERGAYTGATHSRAGRFERANGGTLFLDEITSLSLAGQSKLLRALQEREIERVGGVHGIKVNVRVVAATNVDLR
KAVAEGDFREDLFYRLNVYPIALPPLRERRDDIPLLINFFLGRFCQEYGRTPAGLTMRALKTLLGYDFAGNVRELQNLIE
RGLIASDEGQAIDLVHIFRNESLPRDTYSLNHHGALRQASTAGAQQVPATSLLGTLNQPDKAFSIDELEQRLIQEALDKS
EGNLAAASRLLGLSRAQFAYRLKKRQP

Specific function: Regulatory protein of the TOL plasmid xyl operons. In the presence of m-xylene or m-methylbenzyl alcohol xylR activates both the xylCMABN operon and the regulatory gene xylS; xylS itself activates the xylXYZLTEGFJQKIH operon. XylR interacts with sigma- 54

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=314, Percent_Identity=46.1783439490446, Blast_Score=262, Evalue=4e-71,
Organism=Escherichia coli, GI87082117, Length=335, Percent_Identity=44.4776119402985, Blast_Score=256, Evalue=2e-69,
Organism=Escherichia coli, GI1790437, Length=365, Percent_Identity=40.5479452054795, Blast_Score=238, Evalue=1e-63,
Organism=Escherichia coli, GI1789233, Length=339, Percent_Identity=39.2330383480826, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789087, Length=232, Percent_Identity=48.7068965517241, Blast_Score=227, Evalue=1e-60,
Organism=Escherichia coli, GI87081872, Length=334, Percent_Identity=41.3173652694611, Blast_Score=224, Evalue=9e-60,
Organism=Escherichia coli, GI1790299, Length=346, Percent_Identity=39.8843930635838, Blast_Score=215, Evalue=8e-57,
Organism=Escherichia coli, GI87082152, Length=350, Percent_Identity=38.5714285714286, Blast_Score=214, Evalue=8e-57,
Organism=Escherichia coli, GI1788905, Length=314, Percent_Identity=37.8980891719745, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1786524, Length=342, Percent_Identity=40.0584795321637, Blast_Score=195, Evalue=8e-51,
Organism=Escherichia coli, GI1787583, Length=233, Percent_Identity=42.0600858369099, Blast_Score=175, Evalue=9e-45,
Organism=Escherichia coli, GI1789828, Length=245, Percent_Identity=35.1020408163265, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87081858, Length=306, Percent_Identity=31.6993464052288, Blast_Score=132, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR004096
- InterPro:   IPR010523
- ProDom:   PD485437 [H]

Pfam domain/function: PF02954 HTH_8; PF00158 Sigma54_activat; PF02830 V4R; PF06505 XylR_N [H]

EC number: NA

Molecular weight: Translated: 64695; Mature: 64695

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNPHCELPDHSVPTEHFSPRGDSSQTHAGDSPTAEELTSCLFFSPDDGRIWLNDQRMML
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCEEEECCCEEEE
LHTSSFGTLRREIIERLGLEQARGMFTRAGYLSGARDARLIRERWPQADASSAFRAGTHL
EEECCHHHHHHHHHHHHCHHHHHCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHCCCCH
HTLEGMTKVEPLHFKFDAESGFYEGEFLWHHSCEADEHVAAYGIGQDPVCWTEIGYATGF
HHHCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHH
VSGLFGQMVVFREVECRGMGHANCRVVGKTSEQWGDVERDLSYLRAVNSPAPVHSVPTPA
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCC
ASYEASPPTGTDQPLVGASAAFNAATQALQRVAMTPATVLISGESGVGKEMFARQLHQLS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHH
RHREGPFVALNCAAIPDNLIEAELFGVERGAYTGATHSRAGRFERANGGTLFLDEITSLS
HCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCEEEEEHHHHHH
LAGQSKLLRALQEREIERVGGVHGIKVNVRVVAATNVDLRKAVAEGDFREDLFYRLNVYP
HCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCHHHHHHHCCCHHHHHEEEEEEEE
IALPPLRERRDDIPLLINFFLGRFCQEYGRTPAGLTMRALKTLLGYDFAGNVRELQNLIE
EECCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
RGLIASDEGQAIDLVHIFRNESLPRDTYSLNHHGALRQASTAGAQQVPATSLLGTLNQPD
HCCEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCHHCCHHHHHHCCCCCC
KAFSIDELEQRLIQEALDKSEGNLAAASRLLGLSRAQFAYRLKKRQP
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNNPHCELPDHSVPTEHFSPRGDSSQTHAGDSPTAEELTSCLFFSPDDGRIWLNDQRMML
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEECCCCCEEEECCCEEEE
LHTSSFGTLRREIIERLGLEQARGMFTRAGYLSGARDARLIRERWPQADASSAFRAGTHL
EEECCHHHHHHHHHHHHCHHHHHCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHCCCCH
HTLEGMTKVEPLHFKFDAESGFYEGEFLWHHSCEADEHVAAYGIGQDPVCWTEIGYATGF
HHHCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCCCCEEEECCCCCCCHHHHHHHHHHH
VSGLFGQMVVFREVECRGMGHANCRVVGKTSEQWGDVERDLSYLRAVNSPAPVHSVPTPA
HHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHCCHHHHHHHHHHCCCCCCCCCCCCCC
ASYEASPPTGTDQPLVGASAAFNAATQALQRVAMTPATVLISGESGVGKEMFARQLHQLS
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHH
RHREGPFVALNCAAIPDNLIEAELFGVERGAYTGATHSRAGRFERANGGTLFLDEITSLS
HCCCCCEEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCEEEEEHHHHHH
LAGQSKLLRALQEREIERVGGVHGIKVNVRVVAATNVDLRKAVAEGDFREDLFYRLNVYP
HCCHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCHHHHHHHCCCHHHHHEEEEEEEE
IALPPLRERRDDIPLLINFFLGRFCQEYGRTPAGLTMRALKTLLGYDFAGNVRELQNLIE
EECCCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
RGLIASDEGQAIDLVHIFRNESLPRDTYSLNHHGALRQASTAGAQQVPATSLLGTLNQPD
HCCEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCHHCCHHHHHHCCCCCC
KAFSIDELEQRLIQEALDKSEGNLAAASRLLGLSRAQFAYRLKKRQP
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3169574; 2993247; 2430049 [H]