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The map label for this gene is ttuB [H]

Identifier: 66045951

GI number: 66045951

Start: 3297028

End: 3298422

Strand: Direct

Name: ttuB [H]

Synonym: Psyr_2715

Alternate gene names: 66045951

Gene position: 3297028-3298422 (Clockwise)

Preceding gene: 66045945

Following gene: 66045952

Centisome position: 54.11

GC content: 61.29

Gene sequence:

>1395_bases
ATGAATGGGAGTCGCCTCTTGAATACCGTCCCTGGTACTACGGACGTCACGGTGCTTGCCCGTGCGGCCGCCAAGGTGAA
ACGCCACGTGCTGCCGCTGTTCGTGGTGATGTTCATCGTCAATTACATCGACCGGGTCAATATCGGTTTCGTACGCAGCC
ATCTGGAAACCGATCTGGGTATCGGCGCAGCGGCCTACGGGCTGGGTGCAGGATTGTTCTTTGTCGGTTACGCGCTGTTC
GAAGTCCCCTCCAACATGCTGTTGCAGCGCTACGGTGCCCGCGCCTGGCTGACCCGTATCATGTTCACCTGGGGCGCGGC
CGCCATGGCCATGGCGTTCGTCCAGGGCGAAACCAGCTTTTACGTGCTGCGCTTCATTCTGGGCGCCGCCGAAGCCGGTT
TCTTCCCCGGCATCATCTATTACTTCACCCAATGGCTACCCTCAAGTGACCGCGGCAAGGCCATGGCGCTGTTTCTCAGC
GGCTCGGCGATAGCCTCGGTGATTTCCGGACCGGTGTCCGGCGCCCTGCTCGGTCTCGAGGGCATGAACCTGCATGGCTG
GCAGTGGATGTTCCTGATCGAAGGCTTCGCGTCGATCGTGCTCTGCGGTTTCGTGTGGTTCTGGCTGCAATCACATCCTC
ATGAAGCCCGCTGGCTCAGTGACGAAGAAAAAACCGCGCTCAGCACCGCCATCGCCGAAGAGCAACGGCTGCGCGAAGCT
TCACAAACCGTCAGACCTTCGGTATTCCGACTGTTGGCGGACCGGCAGATCCTGCTGTTCTGCTTCATCTACTTTTCCGT
GGCACTGACCATCTATGGCGCCACCTTCTGGCTGCCGAGCATGATCCGCAAGATGGGCAGTTTCAGCGATTTCGAGGTCG
GGCTGTTCAATTCGATCCCGTGGATCATCTCGATTGTGGCCATGTACGGCTTCGCAGCCCTGGCCGCACGCTTCAAGCAC
CAGCAGGCCTGGGTGGCGGTTACCCTGGTCATCGCCGCCGCCGGCATGTTCATGTCCACGGTGGGCGGTCCGGTGTTCGC
CTTTGTCGCCATCTGCTTCGCGGCAATCGGTTTCAAGGCCGCGTCTGCGCTGTTCTGGCCAATCCCTCAAGGCTATCTGG
ATGCACGCATTGCTGCTGCGGTCATTGCGCTGATCAACTCCATCGGCAACCTGGGCGGTTTCGTCGCACCGACCACGTTC
GGCTTTCTGGAACAGACCACCGGTTCGATTCAGGGCGGTCTGTATGGCCTGGCAGCGACATCGCTGCTCGCTGCCGTGGT
GATCTTCTTCGCCCGCACCACGCCACGCGGTGACCGCGGCCGCCCGTCCAGGGCTGAGCGGCCCGCAGCGCTCAGCCCTG
CCGTCAATGGCACCCCTTCCAGCCTCAAACCCTGA

Upstream 100 bases:

>100_bases
AAGTACAGCGATCAATACAATCTGGGTATCAATCAAGTCACTAACTGGATTGGACGGGAATAATACACGCCGCCATGATC
GACTCATCCCCAAAAAAACA

Downstream 100 bases:

>100_bases
CCTCCGGGAGACCGCCCTTTGAAAATCATCCGTGTAACCGTGACCCCTATCGCCTTTCGCGACCCGCCGTTGCTCAACGC
CAGTGGTATTCACGAACCCT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MNGSRLLNTVPGTTDVTVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLGIGAAAYGLGAGLFFVGYALF
EVPSNMLLQRYGARAWLTRIMFTWGAAAMAMAFVQGETSFYVLRFILGAAEAGFFPGIIYYFTQWLPSSDRGKAMALFLS
GSAIASVISGPVSGALLGLEGMNLHGWQWMFLIEGFASIVLCGFVWFWLQSHPHEARWLSDEEKTALSTAIAEEQRLREA
SQTVRPSVFRLLADRQILLFCFIYFSVALTIYGATFWLPSMIRKMGSFSDFEVGLFNSIPWIISIVAMYGFAALAARFKH
QQAWVAVTLVIAAAGMFMSTVGGPVFAFVAICFAAIGFKAASALFWPIPQGYLDARIAAAVIALINSIGNLGGFVAPTTF
GFLEQTTGSIQGGLYGLAATSLLAAVVIFFARTTPRGDRGRPSRAERPAALSPAVNGTPSSLKP

Sequences:

>Translated_464_residues
MNGSRLLNTVPGTTDVTVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLGIGAAAYGLGAGLFFVGYALF
EVPSNMLLQRYGARAWLTRIMFTWGAAAMAMAFVQGETSFYVLRFILGAAEAGFFPGIIYYFTQWLPSSDRGKAMALFLS
GSAIASVISGPVSGALLGLEGMNLHGWQWMFLIEGFASIVLCGFVWFWLQSHPHEARWLSDEEKTALSTAIAEEQRLREA
SQTVRPSVFRLLADRQILLFCFIYFSVALTIYGATFWLPSMIRKMGSFSDFEVGLFNSIPWIISIVAMYGFAALAARFKH
QQAWVAVTLVIAAAGMFMSTVGGPVFAFVAICFAAIGFKAASALFWPIPQGYLDARIAAAVIALINSIGNLGGFVAPTTF
GFLEQTTGSIQGGLYGLAATSLLAAVVIFFARTTPRGDRGRPSRAERPAALSPAVNGTPSSLKP
>Mature_464_residues
MNGSRLLNTVPGTTDVTVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLGIGAAAYGLGAGLFFVGYALF
EVPSNMLLQRYGARAWLTRIMFTWGAAAMAMAFVQGETSFYVLRFILGAAEAGFFPGIIYYFTQWLPSSDRGKAMALFLS
GSAIASVISGPVSGALLGLEGMNLHGWQWMFLIEGFASIVLCGFVWFWLQSHPHEARWLSDEEKTALSTAIAEEQRLREA
SQTVRPSVFRLLADRQILLFCFIYFSVALTIYGATFWLPSMIRKMGSFSDFEVGLFNSIPWIISIVAMYGFAALAARFKH
QQAWVAVTLVIAAAGMFMSTVGGPVFAFVAICFAAIGFKAASALFWPIPQGYLDARIAAAVIALINSIGNLGGFVAPTTF
GFLEQTTGSIQGGLYGLAATSLLAAVVIFFARTTPRGDRGRPSRAERPAALSPAVNGTPSSLKP

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=383, Percent_Identity=24.2819843342037, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI154350196, Length=382, Percent_Identity=21.7277486910995, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI21322234, Length=357, Percent_Identity=24.3697478991597, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI87082071, Length=421, Percent_Identity=35.6294536817102, Blast_Score=265, Evalue=6e-72,
Organism=Escherichia coli, GI87082320, Length=430, Percent_Identity=22.5581395348837, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1789152, Length=440, Percent_Identity=25.4545454545455, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1789515, Length=445, Percent_Identity=24.4943820224719, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI2367379, Length=442, Percent_Identity=23.7556561085973, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI2367193, Length=319, Percent_Identity=22.5705329153605, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321698, Length=351, Percent_Identity=22.5071225071225, Blast_Score=89, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319876, Length=435, Percent_Identity=22.0689655172414, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322025, Length=179, Percent_Identity=25.6983240223464, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6322612, Length=244, Percent_Identity=22.5409836065574, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639764, Length=369, Percent_Identity=23.8482384823848, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573708, Length=421, Percent_Identity=22.0902612826603, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28573707, Length=421, Percent_Identity=22.0902612826603, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24658696, Length=410, Percent_Identity=20.2439024390244, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24655271, Length=365, Percent_Identity=21.6438356164384, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130135, Length=365, Percent_Identity=21.6438356164384, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI20130167, Length=362, Percent_Identity=20.9944751381215, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583789, Length=350, Percent_Identity=20.5714285714286, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50225; Mature: 50225

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGSRLLNTVPGTTDVTVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
IGAAAYGLGAGLFFVGYALFEVPSNMLLQRYGARAWLTRIMFTWGAAAMAMAFVQGETSF
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
YVLRFILGAAEAGFFPGIIYYFTQWLPSSDRGKAMALFLSGSAIASVISGPVSGALLGLE
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCHHHHEECCC
GMNLHGWQWMFLIEGFASIVLCGFVWFWLQSHPHEARWLSDEEKTALSTAIAEEQRLREA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
SQTVRPSVFRLLADRQILLFCFIYFSVALTIYGATFWLPSMIRKMGSFSDFEVGLFNSIP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCHH
WIISIVAMYGFAALAARFKHQQAWVAVTLVIAAAGMFMSTVGGPVFAFVAICFAAIGFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ASALFWPIPQGYLDARIAAAVIALINSIGNLGGFVAPTTFGFLEQTTGSIQGGLYGLAAT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCHHHHHHH
SLLAAVVIFFARTTPRGDRGRPSRAERPAALSPAVNGTPSSLKP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNGSRLLNTVPGTTDVTVLARAAAKVKRHVLPLFVVMFIVNYIDRVNIGFVRSHLETDLG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCC
IGAAAYGLGAGLFFVGYALFEVPSNMLLQRYGARAWLTRIMFTWGAAAMAMAFVQGETSF
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHH
YVLRFILGAAEAGFFPGIIYYFTQWLPSSDRGKAMALFLSGSAIASVISGPVSGALLGLE
HHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHCCHHHHEECCC
GMNLHGWQWMFLIEGFASIVLCGFVWFWLQSHPHEARWLSDEEKTALSTAIAEEQRLREA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHH
SQTVRPSVFRLLADRQILLFCFIYFSVALTIYGATFWLPSMIRKMGSFSDFEVGLFNSIP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCHH
WIISIVAMYGFAALAARFKHQQAWVAVTLVIAAAGMFMSTVGGPVFAFVAICFAAIGFKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
ASALFWPIPQGYLDARIAAAVIALINSIGNLGGFVAPTTFGFLEQTTGSIQGGLYGLAAT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHCCCHHHHHHH
SLLAAVVIFFARTTPRGDRGRPSRAERPAALSPAVNGTPSSLKP
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8672817 [H]