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The map label for this gene is arnA

Identifier: 66045927

GI number: 66045927

Start: 3267178

End: 3269172

Strand: Direct

Name: arnA

Synonym: Psyr_2691

Alternate gene names: 66045927

Gene position: 3267178-3269172 (Clockwise)

Preceding gene: 66045926

Following gene: 66045928

Centisome position: 53.62

GC content: 59.65

Gene sequence:

>1995_bases
ATGAGCACTAAAGCTGTCGTTTTCGCTTATCACGATATTGGCTGTGTCGGCCTGCAAGCGTTGCTGGATGCAGGCTATGA
GATTGCGGCGGTGTTCACCCATGCCGACGACCCCAGGGAAAAAACCTTTTTCGGCTCTGTGGCGCAGCTGTGCGCCCGGC
ACGGCATTGCAGTGCATGCCCCCGAGGACCCGAATCACCCGCTATGGGTAGAGCGCATCGGCAAACTGGCGCCGGACTTC
ATTTTCTCCTTCTACTATCGCCAGTTACTCGGCGATTCGTTGCTGGCCTGCGCGAAAAAAGCTGCACTGAACCTGCATGG
CTCGCTGCTTCCGCGTTATCGCGGACGCGCGCCGGCCAACTGGGTGCTGGTCAACGGCGAAAGCGAAACCGGCGTTACCC
TGCATCAGATGGTCAAACGCGCCGATGCCGGGCCGATAGTCGCCCAGCAGCGGGTCTCGATCAGTGCCACCGATACCGCC
TTGACGCTGCATGGCAAATTGCGTGACGCCGCCGCTGACCTGCTCTGCGAGACACTGCCCTTGCTCGCCGCACAAGGGCA
ACTGCCAGCGACACCCCAGGATGAATCGCGTGCGACGTATTTCGGTCGGCGCACCCCGGCCGACGGTTTGATCGACTGGT
CGCTGCCAGCCACTCAGCTCTATAACCTGATCCGCGCGGTAACACAGCCCTACCCTGGCGCGTTTTGCCCGGTCGGCGAC
AACAAGCTGATCGTCTGGGCTGCCAGCGTGGACACAAGCAGCAATGGCGAGGCGCCGGGCACGGTCATCAGTCACGAGCC
GTTGCGTATCGCCTGTGGCGAGGGTTCGCTGGTCATCACCGCAGGGCAACGCGGTGACAACGGCTTGTACCTCAGTGGTG
AGCAACTGGCACGCGAATTCGGGCTGGTAGCAGGCTCGCAAATGCTCGATAAGGCAAAGCGCCGGTCGGTTCGTCGTACC
CGCGTGTTGATCCTCGGCGTCAACGGTTTCATCGGCAACCACCTGTCAGAGCGTCTGTTGCAGGATGACCGTTACGAAAT
CTACGGCATGGATATCGGCTCGGACGCTATCGAGCGCTTGCGCGCCAAGCCGAACTTTCACTTCATCGAAGGTGACATCA
GCATCCACACCGAGTGGATCGAATACCACATCAAGAAGTGCGATGTCGTGCTGCCGCTGGTGGCTATCGCCACGCCGATT
GAATACACGCGCAATCCACTGCGGGTCTTCGAGCTGGATTTCGAAGAGAACCTGAAGATCGTCCGCTACTGCGTCAAGTA
CAACAAGCGTGTGATTTTCCCGTCCACGTCCGAAGTCTATGGCATGTGCCAGGACGCAAACTTCAACGAGGACACCTCCA
ACCTGATCGTTGGCCCGATCAACAAGCAGCGCTGGATCTACTCGGTGTCCAAGCAACTGCTGGACCGGGTGATCTGGGCC
TATGGCCAGAAAGGCCTGCAATTCACCCTGTTTCGCCCGTTCAACTGGATGGGACCGCGTCTGGACCGCCTGGATTCGGC
GCGCATTGGCAGTTCGCGGGCCATCACCCAACTGATCCTGCACCTGGTCGAAGGCACGCCCATTCGCCTGGTGGACGGCG
GCGCCCAGAAGCGCTGTTTCACCGATGTCGTCGACGGCATCGAAGCGCTGGCGCGGATCATCGAAAACCGCGATGGGCGC
TGTAACGGACAGATCATCAACATCGGCAACCCCGACAACGAAGCCAGCATCCGTCAATTGGGTGAAGAGCTGCTTCGCCA
GTTCGAAGCCCATCCGTTGCGCGGCCATTTCCCGCCTTTCGCGGGCTTTCGTGAAGTCGAAAGCCAGTCCTTCTATGGCA
AGGGCTATCAGGATGTCAGCCATCGCACGCCGAGCATCGACAACGCCAAAAAGCTGATTGGCTGGACGCCGGGTATCGAG
CTGAGCGAAACCATCGGCAAAACCCTGGATTTCTTCCTGCGCGAAGCCATGGCTGAAAAAGCGGATCAGTGCTGA

Upstream 100 bases:

>100_bases
GTCCGCGGTTCTTCATCGAAAAAATCGTGCGCAGCTCGTCACCGGTTGCCACCGACAGCATTGATTCCTCTGTAACTCCC
TATATGAACAAGGTCGCGCC

Downstream 100 bases:

>100_bases
TGCAGGCAGGCCTGAGAATCGATGTCGACACTTACCGGGGCACCCGTGAGGGCGTGCCCCGGCTGCTGGACATACTCGAC
GAAGCGCAGGTCAAGGCGAC

Product: bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase

Number of amino acids: Translated: 664; Mature: 663

Protein sequence:

>664_residues
MSTKAVVFAYHDIGCVGLQALLDAGYEIAAVFTHADDPREKTFFGSVAQLCARHGIAVHAPEDPNHPLWVERIGKLAPDF
IFSFYYRQLLGDSLLACAKKAALNLHGSLLPRYRGRAPANWVLVNGESETGVTLHQMVKRADAGPIVAQQRVSISATDTA
LTLHGKLRDAAADLLCETLPLLAAQGQLPATPQDESRATYFGRRTPADGLIDWSLPATQLYNLIRAVTQPYPGAFCPVGD
NKLIVWAASVDTSSNGEAPGTVISHEPLRIACGEGSLVITAGQRGDNGLYLSGEQLAREFGLVAGSQMLDKAKRRSVRRT
RVLILGVNGFIGNHLSERLLQDDRYEIYGMDIGSDAIERLRAKPNFHFIEGDISIHTEWIEYHIKKCDVVLPLVAIATPI
EYTRNPLRVFELDFEENLKIVRYCVKYNKRVIFPSTSEVYGMCQDANFNEDTSNLIVGPINKQRWIYSVSKQLLDRVIWA
YGQKGLQFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILHLVEGTPIRLVDGGAQKRCFTDVVDGIEALARIIENRDGR
CNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRGHFPPFAGFREVESQSFYGKGYQDVSHRTPSIDNAKKLIGWTPGIE
LSETIGKTLDFFLREAMAEKADQC

Sequences:

>Translated_664_residues
MSTKAVVFAYHDIGCVGLQALLDAGYEIAAVFTHADDPREKTFFGSVAQLCARHGIAVHAPEDPNHPLWVERIGKLAPDF
IFSFYYRQLLGDSLLACAKKAALNLHGSLLPRYRGRAPANWVLVNGESETGVTLHQMVKRADAGPIVAQQRVSISATDTA
LTLHGKLRDAAADLLCETLPLLAAQGQLPATPQDESRATYFGRRTPADGLIDWSLPATQLYNLIRAVTQPYPGAFCPVGD
NKLIVWAASVDTSSNGEAPGTVISHEPLRIACGEGSLVITAGQRGDNGLYLSGEQLAREFGLVAGSQMLDKAKRRSVRRT
RVLILGVNGFIGNHLSERLLQDDRYEIYGMDIGSDAIERLRAKPNFHFIEGDISIHTEWIEYHIKKCDVVLPLVAIATPI
EYTRNPLRVFELDFEENLKIVRYCVKYNKRVIFPSTSEVYGMCQDANFNEDTSNLIVGPINKQRWIYSVSKQLLDRVIWA
YGQKGLQFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILHLVEGTPIRLVDGGAQKRCFTDVVDGIEALARIIENRDGR
CNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRGHFPPFAGFREVESQSFYGKGYQDVSHRTPSIDNAKKLIGWTPGIE
LSETIGKTLDFFLREAMAEKADQC
>Mature_663_residues
STKAVVFAYHDIGCVGLQALLDAGYEIAAVFTHADDPREKTFFGSVAQLCARHGIAVHAPEDPNHPLWVERIGKLAPDFI
FSFYYRQLLGDSLLACAKKAALNLHGSLLPRYRGRAPANWVLVNGESETGVTLHQMVKRADAGPIVAQQRVSISATDTAL
TLHGKLRDAAADLLCETLPLLAAQGQLPATPQDESRATYFGRRTPADGLIDWSLPATQLYNLIRAVTQPYPGAFCPVGDN
KLIVWAASVDTSSNGEAPGTVISHEPLRIACGEGSLVITAGQRGDNGLYLSGEQLAREFGLVAGSQMLDKAKRRSVRRTR
VLILGVNGFIGNHLSERLLQDDRYEIYGMDIGSDAIERLRAKPNFHFIEGDISIHTEWIEYHIKKCDVVLPLVAIATPIE
YTRNPLRVFELDFEENLKIVRYCVKYNKRVIFPSTSEVYGMCQDANFNEDTSNLIVGPINKQRWIYSVSKQLLDRVIWAY
GQKGLQFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILHLVEGTPIRLVDGGAQKRCFTDVVDGIEALARIIENRDGRC
NGQIINIGNPDNEASIRQLGEELLRQFEAHPLRGHFPPFAGFREVESQSFYGKGYQDVSHRTPSIDNAKKLIGWTPGIEL
SETIGKTLDFFLREAMAEKADQC

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily

Homologues:

Organism=Homo sapiens, GI42516563, Length=352, Percent_Identity=25.8522727272727, Blast_Score=111, Evalue=3e-24,
Organism=Homo sapiens, GI21614513, Length=245, Percent_Identity=25.3061224489796, Blast_Score=83, Evalue=9e-16,
Organism=Homo sapiens, GI238814322, Length=210, Percent_Identity=27.6190476190476, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI164663775, Length=206, Percent_Identity=29.126213592233, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1788589, Length=652, Percent_Identity=68.558282208589, Blast_Score=934, Evalue=0.0,
Organism=Escherichia coli, GI1789683, Length=278, Percent_Identity=33.8129496402878, Blast_Score=130, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17539532, Length=353, Percent_Identity=24.929178470255, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI133930964, Length=254, Percent_Identity=25.9842519685039, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21356223, Length=438, Percent_Identity=26.7123287671233, Blast_Score=95, Evalue=2e-19,
Organism=Drosophila melanogaster, GI45550868, Length=144, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28571984, Length=144, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARNA_PSEU2 (Q4ZSZ2)

Other databases:

- EMBL:   CP000075
- RefSeq:   YP_235768.1
- ProteinModelPortal:   Q4ZSZ2
- SMR:   Q4ZSZ2
- STRING:   Q4ZSZ2
- GeneID:   3368208
- GenomeReviews:   CP000075_GR
- KEGG:   psb:Psyr_2691
- NMPDR:   fig|205918.4.peg.1767
- eggNOG:   COG0451
- HOGENOM:   HBG298638
- OMA:   KAVVFAY
- ProtClustDB:   PRK08125
- BioCyc:   PSYR205918:PSYR_2691-MONOMER
- HAMAP:   MF_01166
- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.10.25.10
- Gene3D:   G3DSA:3.40.50.170
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF036506

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N; SSF50486 FMT_C_like; SSF53328 formyl_transf

EC number: =2.1.2.13; =1.1.1.305

Molecular weight: Translated: 73758; Mature: 73627

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: ACT_SITE 106-106 ACT_SITE 438-438 ACT_SITE 622-622 BINDING 116-116 BINDING 351-351 BINDING 397-397 BINDING 402-402 BINDING 464-464 BINDING 495-495 BINDING 616-616

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTKAVVFAYHDIGCVGLQALLDAGYEIAAVFTHADDPREKTFFGSVAQLCARHGIAVHA
CCCCEEEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEC
PEDPNHPLWVERIGKLAPDFIFSFYYRQLLGDSLLACAKKAALNLHGSLLPRYRGRAPAN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCC
WVLVNGESETGVTLHQMVKRADAGPIVAQQRVSISATDTALTLHGKLRDAAADLLCETLP
EEEEECCCCCCHHHHHHHHHCCCCCCEECCCEEEEECCEEEEEECHHHHHHHHHHHHHHH
LLAAQGQLPATPQDESRATYFGRRTPADGLIDWSLPATQLYNLIRAVTQPYPGAFCPVGD
HHHCCCCCCCCCCCCCCHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCC
NKLIVWAASVDTSSNGEAPGTVISHEPLRIACGEGSLVITAGQRGDNGLYLSGEQLAREF
CEEEEEEEECCCCCCCCCCCCEECCCCEEEEECCCCEEEEECCCCCCCEEECHHHHHHHH
GLVAGSQMLDKAKRRSVRRTRVLILGVNGFIGNHLSERLLQDDRYEIYGMDIGSDAIERL
HHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
RAKPNFHFIEGDISIHTEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKI
HCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECHHHCHHH
VRYCVKYNKRVIFPSTSEVYGMCQDANFNEDTSNLIVGPINKQRWIYSVSKQLLDRVIWA
HHHHHHHCCEEECCCCHHHHEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
YGQKGLQFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILHLVEGTPIRLVDGGAQKRCF
HCCCCCEEEEECCCCCCCCHHHHCCHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHH
TDVVDGIEALARIIENRDGRCNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRGHFPPF
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
AGFREVESQSFYGKGYQDVSHRTPSIDNAKKLIGWTPGIELSETIGKTLDFFLREAMAEK
CCHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
ADQC
CCCC
>Mature Secondary Structure 
STKAVVFAYHDIGCVGLQALLDAGYEIAAVFTHADDPREKTFFGSVAQLCARHGIAVHA
CCCEEEEEECCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEC
PEDPNHPLWVERIGKLAPDFIFSFYYRQLLGDSLLACAKKAALNLHGSLLPRYRGRAPAN
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCC
WVLVNGESETGVTLHQMVKRADAGPIVAQQRVSISATDTALTLHGKLRDAAADLLCETLP
EEEEECCCCCCHHHHHHHHHCCCCCCEECCCEEEEECCEEEEEECHHHHHHHHHHHHHHH
LLAAQGQLPATPQDESRATYFGRRTPADGLIDWSLPATQLYNLIRAVTQPYPGAFCPVGD
HHHCCCCCCCCCCCCCCHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCCCCCCCCCCC
NKLIVWAASVDTSSNGEAPGTVISHEPLRIACGEGSLVITAGQRGDNGLYLSGEQLAREF
CEEEEEEEECCCCCCCCCCCCEECCCCEEEEECCCCEEEEECCCCCCCEEECHHHHHHHH
GLVAGSQMLDKAKRRSVRRTRVLILGVNGFIGNHLSERLLQDDRYEIYGMDIGSDAIERL
HHHHHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCHHHHHHH
RAKPNFHFIEGDISIHTEWIEYHIKKCDVVLPLVAIATPIEYTRNPLRVFELDFEENLKI
HCCCCEEEEECCEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECHHHCHHH
VRYCVKYNKRVIFPSTSEVYGMCQDANFNEDTSNLIVGPINKQRWIYSVSKQLLDRVIWA
HHHHHHHCCEEECCCCHHHHEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHH
YGQKGLQFTLFRPFNWMGPRLDRLDSARIGSSRAITQLILHLVEGTPIRLVDGGAQKRCF
HCCCCCEEEEECCCCCCCCHHHHCCHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCHHHH
TDVVDGIEALARIIENRDGRCNGQIINIGNPDNEASIRQLGEELLRQFEAHPLRGHFPPF
HHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
AGFREVESQSFYGKGYQDVSHRTPSIDNAKKLIGWTPGIELSETIGKTLDFFLREAMAEK
CCHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
ADQC
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA