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The map label for this gene is dhaK [H]

Identifier: 66045802

GI number: 66045802

Start: 2979654

End: 2980655

Strand: Reverse

Name: dhaK [H]

Synonym: Psyr_2566

Alternate gene names: 66045802

Gene position: 2980655-2979654 (Counterclockwise)

Preceding gene: 66045803

Following gene: 66045801

Centisome position: 48.91

GC content: 61.78

Gene sequence:

>1002_bases
ATGAACCGAGTGATAAACGATCCGGACCAGGTGGTCGAGGACATGCTGCGCGGCATTCTGGTAGCGCACCCCGAGCTGTC
GCAAAGTGAAGGTAACCCGCGGGTCATCAGCAAAACCCGTCCCTCTGATCAAGGACGCGTCGGTATCGTTACCGGCGGCG
GCTCGGGTCATGAACCGGCCTTTCTTGGCTATGTCGGCCCTGGGCTGGTGGATGCGGTAGCGGTCGGCGAGATTTTTTCC
TCGCCTACGGCCAAGAGCTTTTTCGACGCCTTCCGCGCGGCCGATCACGGTGCGGGCATCGCCTGCCTGTACGGCAACTA
CGCGGGCGACAACATGAACGTGAAGCTGGCGATGAAAATGGCCGCCAGCAAAGACCTGCAAGTGCGTACCGTGGTGGCCA
ACGACGATGTGGCCTCGGCACCGAAATCCGATATCGCCAAGCGACGCGGAGTGGCCGGGGAAATTTTCATGTGGAAGATC
GGCGGCGCTGCGGCCGCAAACGGTTACGATCTGGACGGCGTGATCCGCGTCGCGCAGAAGGCCGTGGATCAATGCCGATC
CATCGGTATCGGCCTGACGCCCTGCACCATCGCGGCGGTCGGCAAGCCCAACTTTCAGATCCCCGACGGCAAAATGGAGC
TGGGCATCGGTCACCATGGCGAACCGGGTATCGAAGTCATCGACATCGAGCCTGCAGCGGCCATGGCCGAGCGCATGCTG
GAGCCGATCCTGGCCGACCGGGATTTCAGCGTGGACGACAGCGTAGTCGTGCTGGTTTCAGGCCTCGGTGCCACGCCGGT
GATGGAACTCTACGTGTTCTACGCCGAAGTGGAGCGCCTGCTCAAGGCCCGGGGCTTGAAAATCCATCGTTGCTACGTGG
GCAATTACTTCACGTCGCTGGAGATGATGGGGGTAACCCTGACGCTGCTGGGCCTGGACGCCGAACTGAAAACCCTGATC
GACCACCCTTGCCGGTCCATCGGCATGACCCAGGCGGAGTAA

Upstream 100 bases:

>100_bases
GAGGCGTTTGCCGTCATGGAACGCGGTGATAAATCATTGAAGGTGGTTCTGGAACCCTGATCCGCCCGATCCTTATAAAA
AGAACACAGGAAATCGCGTT

Downstream 100 bases:

>100_bases
ACCATGAGCGAGCAATTCTCTACGCATCTCCCTGCACAACAGGGCACTCCTATCGTTGCCGACCTGGTGAGCGTGATCGT
CGCCAACCGCGACTACCTCA

Product: Glycerone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MNRVINDPDQVVEDMLRGILVAHPELSQSEGNPRVISKTRPSDQGRVGIVTGGGSGHEPAFLGYVGPGLVDAVAVGEIFS
SPTAKSFFDAFRAADHGAGIACLYGNYAGDNMNVKLAMKMAASKDLQVRTVVANDDVASAPKSDIAKRRGVAGEIFMWKI
GGAAAANGYDLDGVIRVAQKAVDQCRSIGIGLTPCTIAAVGKPNFQIPDGKMELGIGHHGEPGIEVIDIEPAAAMAERML
EPILADRDFSVDDSVVVLVSGLGATPVMELYVFYAEVERLLKARGLKIHRCYVGNYFTSLEMMGVTLTLLGLDAELKTLI
DHPCRSIGMTQAE

Sequences:

>Translated_333_residues
MNRVINDPDQVVEDMLRGILVAHPELSQSEGNPRVISKTRPSDQGRVGIVTGGGSGHEPAFLGYVGPGLVDAVAVGEIFS
SPTAKSFFDAFRAADHGAGIACLYGNYAGDNMNVKLAMKMAASKDLQVRTVVANDDVASAPKSDIAKRRGVAGEIFMWKI
GGAAAANGYDLDGVIRVAQKAVDQCRSIGIGLTPCTIAAVGKPNFQIPDGKMELGIGHHGEPGIEVIDIEPAAAMAERML
EPILADRDFSVDDSVVVLVSGLGATPVMELYVFYAEVERLLKARGLKIHRCYVGNYFTSLEMMGVTLTLLGLDAELKTLI
DHPCRSIGMTQAE
>Mature_333_residues
MNRVINDPDQVVEDMLRGILVAHPELSQSEGNPRVISKTRPSDQGRVGIVTGGGSGHEPAFLGYVGPGLVDAVAVGEIFS
SPTAKSFFDAFRAADHGAGIACLYGNYAGDNMNVKLAMKMAASKDLQVRTVVANDDVASAPKSDIAKRRGVAGEIFMWKI
GGAAAANGYDLDGVIRVAQKAVDQCRSIGIGLTPCTIAAVGKPNFQIPDGKMELGIGHHGEPGIEVIDIEPAAAMAERML
EPILADRDFSVDDSVVVLVSGLGATPVMELYVFYAEVERLLKARGLKIHRCYVGNYFTSLEMMGVTLTLLGLDAELKTLI
DHPCRSIGMTQAE

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=327, Percent_Identity=32.7217125382263, Blast_Score=173, Evalue=2e-43,
Organism=Escherichia coli, GI87081857, Length=350, Percent_Identity=35.4285714285714, Blast_Score=217, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17565018, Length=331, Percent_Identity=31.1178247734139, Blast_Score=163, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323570, Length=330, Percent_Identity=31.5151515151515, Blast_Score=146, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6321055, Length=338, Percent_Identity=30.4733727810651, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 35342; Mature: 35342

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRVINDPDQVVEDMLRGILVAHPELSQSEGNPRVISKTRPSDQGRVGIVTGGGSGHEPA
CCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCE
FLGYVGPGLVDAVAVGEIFSSPTAKSFFDAFRAADHGAGIACLYGNYAGDNMNVKLAMKM
EEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEEE
AASKDLQVRTVVANDDVASAPKSDIAKRRGVAGEIFMWKIGGAAAANGYDLDGVIRVAQK
CCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
AVDQCRSIGIGLTPCTIAAVGKPNFQIPDGKMELGIGHHGEPGIEVIDIEPAAAMAERML
HHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCEEEECCHHHHHHHHHH
EPILADRDFSVDDSVVVLVSGLGATPVMELYVFYAEVERLLKARGLKIHRCYVGNYFTSL
HHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHH
EMMGVTLTLLGLDAELKTLIDHPCRSIGMTQAE
HHHCEEEEEEECCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNRVINDPDQVVEDMLRGILVAHPELSQSEGNPRVISKTRPSDQGRVGIVTGGGSGHEPA
CCCCCCCHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCCCE
FLGYVGPGLVDAVAVGEIFSSPTAKSFFDAFRAADHGAGIACLYGNYAGDNMNVKLAMKM
EEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEEEE
AASKDLQVRTVVANDDVASAPKSDIAKRRGVAGEIFMWKIGGAAAANGYDLDGVIRVAQK
CCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
AVDQCRSIGIGLTPCTIAAVGKPNFQIPDGKMELGIGHHGEPGIEVIDIEPAAAMAERML
HHHHHHHCCCCCCCCEEEEECCCCCCCCCCCEEECCCCCCCCCCEEEECCHHHHHHHHHH
EPILADRDFSVDDSVVVLVSGLGATPVMELYVFYAEVERLLKARGLKIHRCYVGNYFTSL
HHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHH
EMMGVTLTLLGLDAELKTLIDHPCRSIGMTQAE
HHHCEEEEEEECCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]