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The map label for this gene is ldc [H]

Identifier: 66045783

GI number: 66045783

Start: 2961449

End: 2962642

Strand: Reverse

Name: ldc [H]

Synonym: Psyr_2547

Alternate gene names: 66045783

Gene position: 2962642-2961449 (Counterclockwise)

Preceding gene: 66045784

Following gene: 66045782

Centisome position: 48.62

GC content: 58.79

Gene sequence:

>1194_bases
TTGTTCAGCCACTCGATAAAGCCGTGGCACGAAGCTTGCTCGAAACTTGCCCGCACTTCGAAACCAGAGGCGTTCAACGT
GGACACACTTTTTGCACAATTAGCCGATGACACCAACGACACCTTCTATACCGTTGACCCGCGCTGGATCACCCAGAATG
CGCAGCAATTCAGCGGCTGTTTTCCAGGTACCGTGCTGTATGCAATGAAGGCCAATCCACTCGTGCACGTGCTTGAAGCC
TTGAGCCAGGGCGGTATCAATCATTTTGACGTGGCGTCGCTTGCCGAGGTGCAGACGGTGCACAACACGCTGCCCAACGC
AGTTCAATACCTGATGAATCCAGTGAAATCCCGCCACTGCCTGCACGAGGCCTACTATCGACATGGCGTACGTTCATTTG
TGCTCGACAGTGAGGAGGAACTCTCGAAGTTGCGGGACGTACTGCCCGAGCGCGACAGCACGATCAGCATGTTCGTGCGC
TACGCGCCCTCCGAGTCGACGGCGGTTTACGATCTCAGAGGCAAATTCGGGGCAAGTCCGGCGTTGGCGACGCAACTGGT
GCATCAAGTGGCGGCCAGCACTGACTGGTCACTCGGGCTGTCCTTCCATGTCGGTTCACAAGCCATTGAAGACGGCCCGT
GGCTGGCAGCCCTCGATGACGCGGACGCCATCGTGCGCGACACCGCCCAGCATGTCAGGCACTTGGATATCGGTGGCGGG
TTTCCGGGCAATTACCTGAACTCCATGGGTAATACGCCGGACCTGGTTGGCAGGGTCTGCGAGCACATTCAGACCAGCCC
GACATTGAAGGATCTGAACCTGATCTGCGAAGCGGGTCGTGGCCTGGTCTACGGCGGCATGTCGCTGTTTGCACGGGTGC
TGTCGAGACGCGAACACAGTGTTTTCTGCGGCGCCGGTATTTTTGGCGGTTTGCTCTCCGCCCAGCAATGGCTGCAATTT
CCCGCACGTGTGTGGCGAGACGCTGCGCCTTACGCCGGCTCGGCGGAAGCCACCTTCAATATCTTTGGCCCCACCTGCGA
CAGCATGGATCGCCTGGCCTTCCCCTACTCGCTCGCCAGCGATATCAGGGAAGGCGACTGGCTGGAGTTTCAATCGACCG
GCGCTTACTCGGTGTCCTTGCGCACCCCGTTCAACGGGTTTTACGCCGACCGCATCATCTCTCTCCCTTCCTGA

Upstream 100 bases:

>100_bases
CGTCTGCACTTAACTGCACCACGCCGATTCGAACACTTTAAAATCGCCCTGTTTTGGTGGGCCGTCTTGTATACATGTTT
ATTAAAGTGTTCTCGTTAAG

Downstream 100 bases:

>100_bases
ATGCCTGAAAAGCGATCTGCCATCATGGTCATAAAAGCTTATTTGTTCCTGCTTGCAGGTATCGTCGCTGAAACAGTAGC
GACCATTGCGCTCAAAGAAA

Product: Orn/DAP/Arg decarboxylase 2:Orn/DAP/Arg decarboxylase 2

Products: NA

Alternate protein names: LDC [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MFSHSIKPWHEACSKLARTSKPEAFNVDTLFAQLADDTNDTFYTVDPRWITQNAQQFSGCFPGTVLYAMKANPLVHVLEA
LSQGGINHFDVASLAEVQTVHNTLPNAVQYLMNPVKSRHCLHEAYYRHGVRSFVLDSEEELSKLRDVLPERDSTISMFVR
YAPSESTAVYDLRGKFGASPALATQLVHQVAASTDWSLGLSFHVGSQAIEDGPWLAALDDADAIVRDTAQHVRHLDIGGG
FPGNYLNSMGNTPDLVGRVCEHIQTSPTLKDLNLICEAGRGLVYGGMSLFARVLSRREHSVFCGAGIFGGLLSAQQWLQF
PARVWRDAAPYAGSAEATFNIFGPTCDSMDRLAFPYSLASDIREGDWLEFQSTGAYSVSLRTPFNGFYADRIISLPS

Sequences:

>Translated_397_residues
MFSHSIKPWHEACSKLARTSKPEAFNVDTLFAQLADDTNDTFYTVDPRWITQNAQQFSGCFPGTVLYAMKANPLVHVLEA
LSQGGINHFDVASLAEVQTVHNTLPNAVQYLMNPVKSRHCLHEAYYRHGVRSFVLDSEEELSKLRDVLPERDSTISMFVR
YAPSESTAVYDLRGKFGASPALATQLVHQVAASTDWSLGLSFHVGSQAIEDGPWLAALDDADAIVRDTAQHVRHLDIGGG
FPGNYLNSMGNTPDLVGRVCEHIQTSPTLKDLNLICEAGRGLVYGGMSLFARVLSRREHSVFCGAGIFGGLLSAQQWLQF
PARVWRDAAPYAGSAEATFNIFGPTCDSMDRLAFPYSLASDIREGDWLEFQSTGAYSVSLRTPFNGFYADRIISLPS
>Mature_397_residues
MFSHSIKPWHEACSKLARTSKPEAFNVDTLFAQLADDTNDTFYTVDPRWITQNAQQFSGCFPGTVLYAMKANPLVHVLEA
LSQGGINHFDVASLAEVQTVHNTLPNAVQYLMNPVKSRHCLHEAYYRHGVRSFVLDSEEELSKLRDVLPERDSTISMFVR
YAPSESTAVYDLRGKFGASPALATQLVHQVAASTDWSLGLSFHVGSQAIEDGPWLAALDDADAIVRDTAQHVRHLDIGGG
FPGNYLNSMGNTPDLVGRVCEHIQTSPTLKDLNLICEAGRGLVYGGMSLFARVLSRREHSVFCGAGIFGGLLSAQQWLQF
PARVWRDAAPYAGSAEATFNIFGPTCDSMDRLAFPYSLASDIREGDWLEFQSTGAYSVSLRTPFNGFYADRIISLPS

Specific function: Decarboxylates both L-lysine and L-ornithine with similar catalytic efficiency [H]

COG id: COG0019

COG function: function code E; Diaminopimelate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family [H]

Homologues:

Organism=Homo sapiens, GI4505489, Length=376, Percent_Identity=26.8617021276596, Blast_Score=105, Evalue=8e-23,
Organism=Homo sapiens, GI16506287, Length=385, Percent_Identity=24.4155844155844, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562780, Length=399, Percent_Identity=28.0701754385965, Blast_Score=98, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6322664, Length=353, Percent_Identity=28.6118980169972, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24586474, Length=348, Percent_Identity=27.8735632183908, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009006
- InterPro:   IPR022643
- InterPro:   IPR022657
- InterPro:   IPR022644
- InterPro:   IPR022653
- InterPro:   IPR000183
- InterPro:   IPR002433 [H]

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC [H]

EC number: =4.1.1.17; =4.1.1.18 [H]

Molecular weight: Translated: 43707; Mature: 43707

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00878 ODR_DC_2_1 ; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSHSIKPWHEACSKLARTSKPEAFNVDTLFAQLADDTNDTFYTVDPRWITQNAQQFSGC
CCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHCCHHHHCCC
FPGTVLYAMKANPLVHVLEALSQGGINHFDVASLAEVQTVHNTLPNAVQYLMNPVKSRHC
CCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHEAYYRHGVRSFVLDSEEELSKLRDVLPERDSTISMFVRYAPSESTAVYDLRGKFGASP
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCH
ALATQLVHQVAASTDWSLGLSFHVGSQAIEDGPWLAALDDADAIVRDTAQHVRHLDIGGG
HHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCEEEECCHHHHHHHHHHHHHEECCCCC
FPGNYLNSMGNTPDLVGRVCEHIQTSPTLKDLNLICEAGRGLVYGGMSLFARVLSRREHS
CCHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCC
VFCGAGIFGGLLSAQQWLQFPARVWRDAAPYAGSAEATFNIFGPTCDSMDRLAFPYSLAS
EEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHHCCCHHHHH
DIREGDWLEFQSTGAYSVSLRTPFNGFYADRIISLPS
HCCCCCCEEEECCCCEEEEEECCCCCHHHHHEECCCC
>Mature Secondary Structure
MFSHSIKPWHEACSKLARTSKPEAFNVDTLFAQLADDTNDTFYTVDPRWITQNAQQFSGC
CCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEECCHHHHCCHHHHCCC
FPGTVLYAMKANPLVHVLEALSQGGINHFDVASLAEVQTVHNTLPNAVQYLMNPVKSRHC
CCCCEEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHEAYYRHGVRSFVLDSEEELSKLRDVLPERDSTISMFVRYAPSESTAVYDLRGKFGASP
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCEEEEECCCCCCCH
ALATQLVHQVAASTDWSLGLSFHVGSQAIEDGPWLAALDDADAIVRDTAQHVRHLDIGGG
HHHHHHHHHHHHCCCCCCEEEEECCCHHHCCCCCEEEECCHHHHHHHHHHHHHEECCCCC
FPGNYLNSMGNTPDLVGRVCEHIQTSPTLKDLNLICEAGRGLVYGGMSLFARVLSRREHS
CCHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCC
VFCGAGIFGGLLSAQQWLQFPARVWRDAAPYAGSAEATFNIFGPTCDSMDRLAFPYSLAS
EEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCHHHHCCCHHHHH
DIREGDWLEFQSTGAYSVSLRTPFNGFYADRIISLPS
HCCCCCCEEEECCCCEEEEEECCCCCHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11073919 [H]