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The map label for this gene is metH [H]

Identifier: 66045700

GI number: 66045700

Start: 2852906

End: 2856625

Strand: Reverse

Name: metH [H]

Synonym: Psyr_2464

Alternate gene names: 66045700

Gene position: 2856625-2852906 (Counterclockwise)

Preceding gene: 66045703

Following gene: 66045698

Centisome position: 46.88

GC content: 60.94

Gene sequence:

>3720_bases
ATGTCTGACCGCAGCGCCCGCCATCAAGCTTTTCTCACTGCTCTGAAACAGAGGATCCTGATCCTCGATGGCGGCATGGG
CACCATGATCCAGAGCTACAGGCTCGAAGAACAGGATTACCGCGGCAAGCGTTTTGCCGACTGGCCCAGCGATGTCAAAG
GCAACAATGACCTGTTGATCCTGACCCGCCCTGATGTGATCGGCGCTATTGAGAAGGCTTATCTGGATGCTGGCGCCGAC
ATCCTCGAAACCAACACATTCAACGCCACCCAGGTGTCCCAGGCCGACTACGGCATGGAATCGATCGTTTACGAGCTGAA
CGTCGAAGGCGCGCGCCTGGCGCGCAAGGTCGCAGACGCCAAGACACTGGAAACCCCGGACAGGCCGCGCTTCGTGGCCG
GTGTGCTGGGCCCCACCAGTCGCACCTGCTCGCTGTCGCCGGACGTCAATAACCCCGGCTATCGCAATGTGACCTTTGAC
GAACTGGTCGAGAACTACACCGAAGCGACCAAGGGGCTGATCGAAGGCGGCGCCGACCTGATCCTCATCGAGACCATTTT
CGACACGCTCAACGCCAAGGCGGCGATCTTTGCCGTACAGGGTGTATTCGAAGAAGTCGGCTTTGAGCTGCCGATCATGA
TTTCCGGGACCATCACCGACGCATCCGGGCGCACCCTGTCCGGCCAGACCACCGAAGCGTTCTGGAACTCGATCAGCCAT
GCAAAACCTATCTCGGTCGGCCTGAACTGCGCACTGGGCGCCAGCGAACTGCGTCCTTACCTGCAAGAGCTGGCCAATAA
AGCCAACACCCATGTCTCCGCGCACCCCAACGCCGGCTTGCCGAATGCATTTGGCGAATACGACGAACTGCCGAGCCAGA
CGGCGAAGATCATCGAAGAATTCGCCCAGAGCGGCTTCCTGAACATCGTCGGCGGCTGCTGCGGTACGACACCGGCGCAC
ATCAAGGCGATCGCCGAGGCGGTTTCGGGTTACGCGCCGCGGGAAATTCCGGACATCCCCAAGGCCTGCCGCCTGTCGGG
CCTCGAACCGTTCACCATCGATCGCCAGTCGCTGTTCGTCAACGTCGGCGAGCGTACCAATATCACTGGCTCCGCCCGCT
TCGCCCGCCTGATCCGTGAAGACAATTACACCGAAGCCCTCGAAGTCGCCCTGCAGCAGGTCGAAGCCGGCGCTCAGGTG
ATCGATATCAACATGGACGAAGGCATGCTCGACTCGAAGAAGGCCATGGTGACCTTCCTCAACCTGATCGCAGGCGAGCC
GGACATCTCCCGCGTACCGATCATGATCGACTCCTCGAAATGGGAAGTGATCGAGGCCGGCCTCAAGTGCATCCAGGGCA
AGGGCATCGTCAACTCCATCAGCATGAAGGAAGGCGTCGAGCAGTTCATTCATCACGCCCGCCTGTGCAAGCGCTATGGC
GCGGCGGTGGTGGTCATGGCCTTCGATGAACAGGGTCAGGCCGACACCGAAGCGCGCAAAAAGGAAATCTGCAAGCGCTC
CTACGACATTCTGGTCGACGAAGTGGGCTTCCCGCCGGAAGACATCATCTTCGACCCGAACATCTTCGCCATCGCCACCG
GTATCGAAGAACACAACAACTATGCCGTGGACTTCATCAACGCCTGCGCCTACATCCGCGACGAGCTGCCGTATGCGCTG
ACCTCGGGTGGCGTGTCCAACGTATCTTTCTCGTTCCGCGGCAACAACCCGGTACGCGAGGCGATCCACTCGGTGTTCCT
GCTGCATGCGATCCGTAATGGCCTGAGCATGGGCATCGTCAACGCCGGGCAGCTGGAAATCTACGACCAGATCCCCGCCG
AACTGCGCGACTGTGTCGAAGACGTGGTGCTCAACCGCAACCCCGAAGGCACCGATGCACTGCTGGCGATTGCCGACAAG
TTCAAGGGGGATGGCAGCGTCAAGGAAGCCGAAACCGAAGAATGGCGCAGCTGGCCGGTCAATCAGCGTCTGGAGCACGC
GCTGGTCAAGGGTATTACCACCCATATCGTGCAGGACACCGAAGAGTCGCGCGTGGGGTTCGCGCGGCCTATCGAAGTGA
TCGAAGGCCCGCTGATGGCGGGCATGAACGTGGTCGGCGACCTGTTTGGTGCAGGCAAGATGTTCCTGCCCCAGGTGGTC
AAGTCCGCGCGCGTGATGAAACAGGCCGTGGCGCACCTGATTCCGTTCATCGAGCTGGAAAAGGGCGACAAGCCCGAAGC
CAAGGGCAAGATCCTGATGGCGACGGTCAAGGGCGACGTGCATGACATCGGCAAGAACATCGTCGGCGTGGTACTGGGCT
GTAACGGCTACGACATCGTCGATCTGGGCGTAATGGTGCCTGCCGAGAAAATCCTGCAAGTGGCCCGCGACGAGAAATGC
GACATCATCGGCCTCTCCGGCCTGATCACGCCGTCACTGGACGAAATGGTGCATGTTGCCCGGGAAATGCAGCGCCAGGA
CTTCCACCTGCCGCTGATGATCGGCGGCGCGACCACCTCCAAGGCGCACACGGCGGTGAAGATCGAACCCAAATACAGCA
ATGATGCCGTGATCTACGTCACCGATGCTTCCCGAGCAGTCGGCGTCGCGACCCAGTTACTGTCGAAAGAGCTGAAGCCG
GCCTTCATTGAAAAGACCCGCCTGGAATACGTCGAAGTACGTGAACGCACCTCGGCACGCAGCGCGCGTACCGAGCGCCT
GAGTTACGGCGCTGCAGTGGCTAAAAAGCCGCAGTTCGACTGGGAAAACTACACCCCGGCCCAACCGACGTTCACCGGCA
CCCGGGTCCTGCAGGATATCGACCTGAACGTGCTGGCCGAGTACATCGACTGGACGCCGTTCTTCATTTCCTGGGACCTG
GCTGGCAAGTACCCGCGCATCCTCACCGACGAAGTGGTCGGTGAAGCGGCCACCGCTCTGTACGCCGACGCCACGCAGAT
GCTGCGCAAGCTGATCGACGAGAAGCTGATCAGCGCCCGCGCGGTCTTCGGCTTCTGGCCAGCCAATCAGGTCAATGACG
ACGATCTGGAAGTCTATGACGATGACGGCAAGCCGTTGGCGAAGCTGCATCACCTGCGCCAGCAGACCATCAAGCCCGAC
GGCAAGCCGAACTTCTCGCTGGCCGACTTCGTTGCACCAAAGGACAGTGGCCTGACCGACTACATCGGCGGGTTCATCAC
CACAGCCGGCATCGGCGCCGAGGAAGTCGCCAAGGCTTATCAGGACAAAGGCGACGACTACAACTCGATCATGGTCAAGG
CGCTTGCCGACCGTCTCGCCGAAGCCTGCGCCGAATGGCTGCACCAGCAGGTGCGCAAGGAATACTGGGGTTATGCGCAG
GACGAAGCGCTGGACAACGAAGCGCTGATCAAGGAGCAATACATGGGCATCCGCCCGGCGCCGGGCTACCCGGCGTGCCC
CGATCACACGGAAAAGGGCACCCTGTTCGCCCTGCTCGATCCGCTACCGGAAGGCAGCGCCGAGCACACGGCAGGCAAGA
GCGGCGTGTTCCTGACCGAGCACTACGCGATGTTCCCGGCTGCAGCGGTCAGCGGCTGGTATTTCGCCCATCCCCAGGCG
CAGTACTTCGCCGTGGGCAAGATCGACAAGGATCAGGTCGAAAGCTACACCGCTCGCAAGGGTCAGGACCTGAGCGTCAC
CGAACGCTGGCTGGCACCGAACCTGGGCTACGACGAGTAA

Upstream 100 bases:

>100_bases
ACATGAATGATTTTCATGCAAAAGGCGCAACAACACTAAAACCGTTCCGGTTTGCTATCATCCCGTTCTTTAAAGAATCG
ACCTTTTCAAGGTAGCCCCC

Downstream 100 bases:

>100_bases
CGCCTGACCGGTCATCTGCCGCCTGAGTGATCAGGCGGCAACATGCCTTTCAGCGAAAATGGCGACGCATCGCCAGAAGC
CTCCACATTGAATGCCTGGA

Product: B12-dependent methionine synthase

Products: NA

Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12 dependent; MS [H]

Number of amino acids: Translated: 1239; Mature: 1238

Protein sequence:

>1239_residues
MSDRSARHQAFLTALKQRILILDGGMGTMIQSYRLEEQDYRGKRFADWPSDVKGNNDLLILTRPDVIGAIEKAYLDAGAD
ILETNTFNATQVSQADYGMESIVYELNVEGARLARKVADAKTLETPDRPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFD
ELVENYTEATKGLIEGGADLILIETIFDTLNAKAAIFAVQGVFEEVGFELPIMISGTITDASGRTLSGQTTEAFWNSISH
AKPISVGLNCALGASELRPYLQELANKANTHVSAHPNAGLPNAFGEYDELPSQTAKIIEEFAQSGFLNIVGGCCGTTPAH
IKAIAEAVSGYAPREIPDIPKACRLSGLEPFTIDRQSLFVNVGERTNITGSARFARLIREDNYTEALEVALQQVEAGAQV
IDINMDEGMLDSKKAMVTFLNLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFIHHARLCKRYG
AAVVVMAFDEQGQADTEARKKEICKRSYDILVDEVGFPPEDIIFDPNIFAIATGIEEHNNYAVDFINACAYIRDELPYAL
TSGGVSNVSFSFRGNNPVREAIHSVFLLHAIRNGLSMGIVNAGQLEIYDQIPAELRDCVEDVVLNRNPEGTDALLAIADK
FKGDGSVKEAETEEWRSWPVNQRLEHALVKGITTHIVQDTEESRVGFARPIEVIEGPLMAGMNVVGDLFGAGKMFLPQVV
KSARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIVDLGVMVPAEKILQVARDEKC
DIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTSKAHTAVKIEPKYSNDAVIYVTDASRAVGVATQLLSKELKP
AFIEKTRLEYVEVRERTSARSARTERLSYGAAVAKKPQFDWENYTPAQPTFTGTRVLQDIDLNVLAEYIDWTPFFISWDL
AGKYPRILTDEVVGEAATALYADATQMLRKLIDEKLISARAVFGFWPANQVNDDDLEVYDDDGKPLAKLHHLRQQTIKPD
GKPNFSLADFVAPKDSGLTDYIGGFITTAGIGAEEVAKAYQDKGDDYNSIMVKALADRLAEACAEWLHQQVRKEYWGYAQ
DEALDNEALIKEQYMGIRPAPGYPACPDHTEKGTLFALLDPLPEGSAEHTAGKSGVFLTEHYAMFPAAAVSGWYFAHPQA
QYFAVGKIDKDQVESYTARKGQDLSVTERWLAPNLGYDE

Sequences:

>Translated_1239_residues
MSDRSARHQAFLTALKQRILILDGGMGTMIQSYRLEEQDYRGKRFADWPSDVKGNNDLLILTRPDVIGAIEKAYLDAGAD
ILETNTFNATQVSQADYGMESIVYELNVEGARLARKVADAKTLETPDRPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFD
ELVENYTEATKGLIEGGADLILIETIFDTLNAKAAIFAVQGVFEEVGFELPIMISGTITDASGRTLSGQTTEAFWNSISH
AKPISVGLNCALGASELRPYLQELANKANTHVSAHPNAGLPNAFGEYDELPSQTAKIIEEFAQSGFLNIVGGCCGTTPAH
IKAIAEAVSGYAPREIPDIPKACRLSGLEPFTIDRQSLFVNVGERTNITGSARFARLIREDNYTEALEVALQQVEAGAQV
IDINMDEGMLDSKKAMVTFLNLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFIHHARLCKRYG
AAVVVMAFDEQGQADTEARKKEICKRSYDILVDEVGFPPEDIIFDPNIFAIATGIEEHNNYAVDFINACAYIRDELPYAL
TSGGVSNVSFSFRGNNPVREAIHSVFLLHAIRNGLSMGIVNAGQLEIYDQIPAELRDCVEDVVLNRNPEGTDALLAIADK
FKGDGSVKEAETEEWRSWPVNQRLEHALVKGITTHIVQDTEESRVGFARPIEVIEGPLMAGMNVVGDLFGAGKMFLPQVV
KSARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIVDLGVMVPAEKILQVARDEKC
DIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTSKAHTAVKIEPKYSNDAVIYVTDASRAVGVATQLLSKELKP
AFIEKTRLEYVEVRERTSARSARTERLSYGAAVAKKPQFDWENYTPAQPTFTGTRVLQDIDLNVLAEYIDWTPFFISWDL
AGKYPRILTDEVVGEAATALYADATQMLRKLIDEKLISARAVFGFWPANQVNDDDLEVYDDDGKPLAKLHHLRQQTIKPD
GKPNFSLADFVAPKDSGLTDYIGGFITTAGIGAEEVAKAYQDKGDDYNSIMVKALADRLAEACAEWLHQQVRKEYWGYAQ
DEALDNEALIKEQYMGIRPAPGYPACPDHTEKGTLFALLDPLPEGSAEHTAGKSGVFLTEHYAMFPAAAVSGWYFAHPQA
QYFAVGKIDKDQVESYTARKGQDLSVTERWLAPNLGYDE
>Mature_1238_residues
SDRSARHQAFLTALKQRILILDGGMGTMIQSYRLEEQDYRGKRFADWPSDVKGNNDLLILTRPDVIGAIEKAYLDAGADI
LETNTFNATQVSQADYGMESIVYELNVEGARLARKVADAKTLETPDRPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFDE
LVENYTEATKGLIEGGADLILIETIFDTLNAKAAIFAVQGVFEEVGFELPIMISGTITDASGRTLSGQTTEAFWNSISHA
KPISVGLNCALGASELRPYLQELANKANTHVSAHPNAGLPNAFGEYDELPSQTAKIIEEFAQSGFLNIVGGCCGTTPAHI
KAIAEAVSGYAPREIPDIPKACRLSGLEPFTIDRQSLFVNVGERTNITGSARFARLIREDNYTEALEVALQQVEAGAQVI
DINMDEGMLDSKKAMVTFLNLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFIHHARLCKRYGA
AVVVMAFDEQGQADTEARKKEICKRSYDILVDEVGFPPEDIIFDPNIFAIATGIEEHNNYAVDFINACAYIRDELPYALT
SGGVSNVSFSFRGNNPVREAIHSVFLLHAIRNGLSMGIVNAGQLEIYDQIPAELRDCVEDVVLNRNPEGTDALLAIADKF
KGDGSVKEAETEEWRSWPVNQRLEHALVKGITTHIVQDTEESRVGFARPIEVIEGPLMAGMNVVGDLFGAGKMFLPQVVK
SARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIVDLGVMVPAEKILQVARDEKCD
IIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTSKAHTAVKIEPKYSNDAVIYVTDASRAVGVATQLLSKELKPA
FIEKTRLEYVEVRERTSARSARTERLSYGAAVAKKPQFDWENYTPAQPTFTGTRVLQDIDLNVLAEYIDWTPFFISWDLA
GKYPRILTDEVVGEAATALYADATQMLRKLIDEKLISARAVFGFWPANQVNDDDLEVYDDDGKPLAKLHHLRQQTIKPDG
KPNFSLADFVAPKDSGLTDYIGGFITTAGIGAEEVAKAYQDKGDDYNSIMVKALADRLAEACAEWLHQQVRKEYWGYAQD
EALDNEALIKEQYMGIRPAPGYPACPDHTEKGTLFALLDPLPEGSAEHTAGKSGVFLTEHYAMFPAAAVSGWYFAHPQAQ
YFAVGKIDKDQVESYTARKGQDLSVTERWLAPNLGYDE

Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]

COG id: COG1410

COG function: function code E; Methionine synthase I, cobalamin-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 pterin-binding domain [H]

Homologues:

Organism=Homo sapiens, GI169790923, Length=1252, Percent_Identity=54.8722044728435, Blast_Score=1346, Evalue=0.0,
Organism=Escherichia coli, GI1790450, Length=1238, Percent_Identity=65.9127625201939, Blast_Score=1645, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535405, Length=1258, Percent_Identity=52.6232114467409, Blast_Score=1295, Evalue=0.0,

Paralogues:

None

Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006158
- InterPro:   IPR011005
- InterPro:   IPR003759
- InterPro:   IPR011822
- InterPro:   IPR000489
- InterPro:   IPR003726
- InterPro:   IPR004223 [H]

Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]

EC number: =2.1.1.13 [H]

Molecular weight: Translated: 135976; Mature: 135844

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRSARHQAFLTALKQRILILDGGMGTMIQSYRLEEQDYRGKRFADWPSDVKGNNDLLI
CCCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCEEE
LTRPDVIGAIEKAYLDAGADILETNTFNATQVSQADYGMESIVYELNVEGARLARKVADA
EECCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHCCHHHEEEEECCCHHHHHHHHHHH
KTLETPDRPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFDELVENYTEATKGLIEGGADL
HCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCE
ILIETIFDTLNAKAAIFAVQGVFEEVGFELPIMISGTITDASGRTLSGQTTEAFWNSISH
EEHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEECCCHHHHHHHHHCC
AKPISVGLNCALGASELRPYLQELANKANTHVSAHPNAGLPNAFGEYDELPSQTAKIIEE
CCCCEECCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHCHHHHHHHHHH
FAQSGFLNIVGGCCGTTPAHIKAIAEAVSGYAPREIPDIPKACRLSGLEPFTIDRQSLFV
HHHCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEECCHHEEE
NVGERTNITGSARFARLIREDNYTEALEVALQQVEAGAQVIDINMDEGMLDSKKAMVTFL
ECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
NLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFIHHARLCKRYG
HHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AAVVVMAFDEQGQADTEARKKEICKRSYDILVDEVGFPPEDIIFDPNIFAIATGIEEHNN
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCEEEEEECHHHCCC
YAVDFINACAYIRDELPYALTSGGVSNVSFSFRGNNPVREAIHSVFLLHAIRNGLSMGIV
CHHHHHHHHHHHHHCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
NAGQLEIYDQIPAELRDCVEDVVLNRNPEGTDALLAIADKFKGDGSVKEAETEEWRSWPV
CCCCEEEHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCH
NQRLEHALVKGITTHIVQDTEESRVGFARPIEVIEGPLMAGMNVVGDLFGAGKMFLPQVV
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHH
KSARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIV
HHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCHHHHCCCEEEEEECCCCCCEE
DLGVMVPAEKILQVARDEKCDIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTS
EECCCCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
KAHTAVKIEPKYSNDAVIYVTDASRAVGVATQLLSKELKPAFIEKTRLEYVEVRERTSAR
CCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
SARTERLSYGAAVAKKPQFDWENYTPAQPTFTGTRVLQDIDLNVLAEYIDWTPFFISWDL
HHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCEEEEEEC
AGKYPRILTDEVVGEAATALYADATQMLRKLIDEKLISARAVFGFWPANQVNDDDLEVYD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEC
DDGKPLAKLHHLRQQTIKPDGKPNFSLADFVAPKDSGLTDYIGGFITTAGIGAEEVAKAY
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
QDKGDDYNSIMVKALADRLAEACAEWLHQQVRKEYWGYAQDEALDNEALIKEQYMGIRPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCCCCC
PGYPACPDHTEKGTLFALLDPLPEGSAEHTAGKSGVFLTEHYAMFPAAAVSGWYFAHPQA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCEEEECCCC
QYFAVGKIDKDQVESYTARKGQDLSVTERWLAPNLGYDE
CEEEECCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDRSARHQAFLTALKQRILILDGGMGTMIQSYRLEEQDYRGKRFADWPSDVKGNNDLLI
CCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCEEE
LTRPDVIGAIEKAYLDAGADILETNTFNATQVSQADYGMESIVYELNVEGARLARKVADA
EECCHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHCCHHHEEEEECCCHHHHHHHHHHH
KTLETPDRPRFVAGVLGPTSRTCSLSPDVNNPGYRNVTFDELVENYTEATKGLIEGGADL
HCCCCCCCCCEEEEECCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCE
ILIETIFDTLNAKAAIFAVQGVFEEVGFELPIMISGTITDASGRTLSGQTTEAFWNSISH
EEHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEECCCHHHHHHHHHCC
AKPISVGLNCALGASELRPYLQELANKANTHVSAHPNAGLPNAFGEYDELPSQTAKIIEE
CCCCEECCCCCCCHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCHHHCHHHHHHHHHH
FAQSGFLNIVGGCCGTTPAHIKAIAEAVSGYAPREIPDIPKACRLSGLEPFTIDRQSLFV
HHHCCCCEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEECCHHEEE
NVGERTNITGSARFARLIREDNYTEALEVALQQVEAGAQVIDINMDEGMLDSKKAMVTFL
ECCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHH
NLIAGEPDISRVPIMIDSSKWEVIEAGLKCIQGKGIVNSISMKEGVEQFIHHARLCKRYG
HHHCCCCCCCCCCEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
AAVVVMAFDEQGQADTEARKKEICKRSYDILVDEVGFPPEDIIFDPNIFAIATGIEEHNN
CEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCEEEEEECHHHCCC
YAVDFINACAYIRDELPYALTSGGVSNVSFSFRGNNPVREAIHSVFLLHAIRNGLSMGIV
CHHHHHHHHHHHHHCCCCEECCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCC
NAGQLEIYDQIPAELRDCVEDVVLNRNPEGTDALLAIADKFKGDGSVKEAETEEWRSWPV
CCCCEEEHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHCCCH
NQRLEHALVKGITTHIVQDTEESRVGFARPIEVIEGPLMAGMNVVGDLFGAGKMFLPQVV
HHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHCCHHHHHHHHHHHHHCCCHHHHHHHH
KSARVMKQAVAHLIPFIELEKGDKPEAKGKILMATVKGDVHDIGKNIVGVVLGCNGYDIV
HHHHHHHHHHHHHCCCEEECCCCCCCCCCCEEEEEECCCHHHHCCCEEEEEECCCCCCEE
DLGVMVPAEKILQVARDEKCDIIGLSGLITPSLDEMVHVAREMQRQDFHLPLMIGGATTS
EECCCCCHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCC
KAHTAVKIEPKYSNDAVIYVTDASRAVGVATQLLSKELKPAFIEKTRLEYVEVRERTSAR
CCCEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
SARTERLSYGAAVAKKPQFDWENYTPAQPTFTGTRVLQDIDLNVLAEYIDWTPFFISWDL
HHHHHHHHHCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCEEEEEEC
AGKYPRILTDEVVGEAATALYADATQMLRKLIDEKLISARAVFGFWPANQVNDDDLEVYD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEC
DDGKPLAKLHHLRQQTIKPDGKPNFSLADFVAPKDSGLTDYIGGFITTAGIGAEEVAKAY
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHH
QDKGDDYNSIMVKALADRLAEACAEWLHQQVRKEYWGYAQDEALDNEALIKEQYMGIRPA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHHHHHHHHHCCCCCC
PGYPACPDHTEKGTLFALLDPLPEGSAEHTAGKSGVFLTEHYAMFPAAAVSGWYFAHPQA
CCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHCCEEEECCCC
QYFAVGKIDKDQVESYTARKGQDLSVTERWLAPNLGYDE
CEEEECCCCHHHHHHHHHCCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]