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The map label for this gene is sir [H]

Identifier: 66045698

GI number: 66045698

Start: 2849581

End: 2851239

Strand: Reverse

Name: sir [H]

Synonym: Psyr_2462

Alternate gene names: 66045698

Gene position: 2851239-2849581 (Counterclockwise)

Preceding gene: 66045700

Following gene: 66045697

Centisome position: 46.79

GC content: 59.73

Gene sequence:

>1659_bases
ATGTACGTATACGACGATTACGATCAGAAGATCATCGAGGACCGCGTCAAGCAGTTCCGGGATCAGACCCGACGCTACCT
GGTCGGGGAACTGAGCGAAGAAGAGTTTCGACCGTTGCGCCTGCAAAACGGTCTTTATGTTCAGCGCTTCGCGCCAATGT
TGCGCGTCGCCGTGCCCTACGGTCAGCTGACCTCGCGTCAGGCGCGGATGATGGCGAAAATTGCGCGCGACTACGATAAA
GGCTACGCGCACATCAGCACCCGCCAGAACGTACAGTTCAACTGGCCTGCGCTTGAAGATGTCCCTGATATTCTCGCTGA
ACTGGCAACCGTGCAGATGCACGCTATCCAGACCAGCGGCAACTGCCTGCGCAACGTCACCACCGACCAGTTTGCCGGTG
TGGCGGCGGACGAACTGGTAGACCCGCGCCCATGGTGCGAGATCGTCCGTCAATGGACCACGTTCCACCCTGAATTCGCT
TACCTGCCGCGCAAGTTCAAGATCGCGATCAATGGCTCGACCAGTGACCGCGCAGCCATCGAAGTGCATGACATCGGCCT
CGAGCCATTGCGCAACGAAGCCGGCGAGCTGGGCTTCCGCGTTCTGGTCGGTGGCGGTCTTGGCCGTACACCGGTCGTCG
GTGCCTTCATCAACGAGTTTCTGCCGTGGCAGGACCTGCTGAGCTACCTCGACGCCATCCTGCGGGTCTACAACCGCTAT
GGCCGTCGCGACAACAAGTACAAGGCGCGCATCAAGATTCTGGTCAAGGCGCTGACCCCTGAAGTGTTTGCCGCCAAGGT
CGAGGCTGAAATGGCTCACCTGCGTGGCGGTCAGACCACCCTGACCGAAGCCGAAGTGCAGCGCGTGTCCCGGCACTTCG
TCGACCCGCAATACAAGGTACTCAGCGATCAGCACGCCGAACTGGCGGCGCTGGATGCTCAACACCCCGGCTTCGCTCGC
TGGCGTCAACGCAATGTGCTGGCGCACAAGAAGCCTGGCTACATTGCCGTGACCCTGTCGCTCAAGCCAACCGGCGTCGC
TCCTGGCGATGTGACCGACAAGCAACTGGACGCCATCGCCGACCTGGCCGATCGCTACAGCTTCGGTCAACTGCGCACCT
CCCACGAGCAGAACATCATCCTTGCCGATGTCGAGCAGAGAGAGCTGTTCACCCTGTGGAACGAGCTGCGCGACAATGGT
TTCGCCACGCCGAACATTGGCCTTCTGACCGACATCATCTGCTGCCCGGGCGGTGACTTCTGCTCGCTGGCCAATGCCAA
GTCGATCCCGATCGCCGAATCCATCCAGCGTCGTTTCGACGATCTTGACTACCTGTTCGATATCGGCGAGCTGGACCTTA
ATATCTCCGGCTGCATGAATGCCTGCGGCCACCACCATGTCGGCCATATCGGCGTGCTGGGCGTGGACAAGAAAGGTGAA
GAGTTCTATCAGGTCTCGCTCGGCGGCAGCGCCAGCCGTGATGCGAGCCTGGGCAAGATTCTCGGCCCCTCCTTTGCCCA
GGAGGCGATGCCGGACGTGATCGAGAAGCTGATCGACGTCTACGTTGAAAAACGTACCGAAGACGAGCGCTTCATCGACA
CCTACCAACGTATTGGCATTGACCCTTTCAAGGAGCGCGTCTATGCAGCGAATCATTAA

Upstream 100 bases:

>100_bases
GCAGAATTGACCAGATGAAGCAGGAAACATCGAGCAGCGGGCTTTTTTCAGACTGACGCCACTGCCCTGCTTCATGACGA
AGCCTGAGAACAGGACCTAT

Downstream 100 bases:

>100_bases
GAACAACGAAGTCATCGATGAAACCTGGCATCTGCTGCCCAAGGACACGACCTTTGACAGCCTGTCGAACTGCGACGACC
TGATCGTGCCGCTGGCGCTG

Product: nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like:nitrite and sulphite reductase 4Fe-4S region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 552

Protein sequence:

>552_residues
MYVYDDYDQKIIEDRVKQFRDQTRRYLVGELSEEEFRPLRLQNGLYVQRFAPMLRVAVPYGQLTSRQARMMAKIARDYDK
GYAHISTRQNVQFNWPALEDVPDILAELATVQMHAIQTSGNCLRNVTTDQFAGVAADELVDPRPWCEIVRQWTTFHPEFA
YLPRKFKIAINGSTSDRAAIEVHDIGLEPLRNEAGELGFRVLVGGGLGRTPVVGAFINEFLPWQDLLSYLDAILRVYNRY
GRRDNKYKARIKILVKALTPEVFAAKVEAEMAHLRGGQTTLTEAEVQRVSRHFVDPQYKVLSDQHAELAALDAQHPGFAR
WRQRNVLAHKKPGYIAVTLSLKPTGVAPGDVTDKQLDAIADLADRYSFGQLRTSHEQNIILADVEQRELFTLWNELRDNG
FATPNIGLLTDIICCPGGDFCSLANAKSIPIAESIQRRFDDLDYLFDIGELDLNISGCMNACGHHHVGHIGVLGVDKKGE
EFYQVSLGGSASRDASLGKILGPSFAQEAMPDVIEKLIDVYVEKRTEDERFIDTYQRIGIDPFKERVYAANH

Sequences:

>Translated_552_residues
MYVYDDYDQKIIEDRVKQFRDQTRRYLVGELSEEEFRPLRLQNGLYVQRFAPMLRVAVPYGQLTSRQARMMAKIARDYDK
GYAHISTRQNVQFNWPALEDVPDILAELATVQMHAIQTSGNCLRNVTTDQFAGVAADELVDPRPWCEIVRQWTTFHPEFA
YLPRKFKIAINGSTSDRAAIEVHDIGLEPLRNEAGELGFRVLVGGGLGRTPVVGAFINEFLPWQDLLSYLDAILRVYNRY
GRRDNKYKARIKILVKALTPEVFAAKVEAEMAHLRGGQTTLTEAEVQRVSRHFVDPQYKVLSDQHAELAALDAQHPGFAR
WRQRNVLAHKKPGYIAVTLSLKPTGVAPGDVTDKQLDAIADLADRYSFGQLRTSHEQNIILADVEQRELFTLWNELRDNG
FATPNIGLLTDIICCPGGDFCSLANAKSIPIAESIQRRFDDLDYLFDIGELDLNISGCMNACGHHHVGHIGVLGVDKKGE
EFYQVSLGGSASRDASLGKILGPSFAQEAMPDVIEKLIDVYVEKRTEDERFIDTYQRIGIDPFKERVYAANH
>Mature_552_residues
MYVYDDYDQKIIEDRVKQFRDQTRRYLVGELSEEEFRPLRLQNGLYVQRFAPMLRVAVPYGQLTSRQARMMAKIARDYDK
GYAHISTRQNVQFNWPALEDVPDILAELATVQMHAIQTSGNCLRNVTTDQFAGVAADELVDPRPWCEIVRQWTTFHPEFA
YLPRKFKIAINGSTSDRAAIEVHDIGLEPLRNEAGELGFRVLVGGGLGRTPVVGAFINEFLPWQDLLSYLDAILRVYNRY
GRRDNKYKARIKILVKALTPEVFAAKVEAEMAHLRGGQTTLTEAEVQRVSRHFVDPQYKVLSDQHAELAALDAQHPGFAR
WRQRNVLAHKKPGYIAVTLSLKPTGVAPGDVTDKQLDAIADLADRYSFGQLRTSHEQNIILADVEQRELFTLWNELRDNG
FATPNIGLLTDIICCPGGDFCSLANAKSIPIAESIQRRFDDLDYLFDIGELDLNISGCMNACGHHHVGHIGVLGVDKKGE
EFYQVSLGGSASRDASLGKILGPSFAQEAMPDVIEKLIDVYVEKRTEDERFIDTYQRIGIDPFKERVYAANH

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

Organism=Escherichia coli, GI1789122, Length=276, Percent_Identity=24.2753623188406, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 62388; Mature: 62388

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVYDDYDQKIIEDRVKQFRDQTRRYLVGELSEEEFRPLRLQNGLYVQRFAPMLRVAVPY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHCCCEEHHHHHHHHHHHCCC
GQLTSRQARMMAKIARDYDKGYAHISTRQNVQFNWPALEDVPDILAELATVQMHAIQTSG
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHEECCC
NCLRNVTTDQFAGVAADELVDPRPWCEIVRQWTTFHPEFAYLPRKFKIAINGSTSDRAAI
CHHHCCCHHHHCCCCHHHCCCCCHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCCCCEEE
EVHDIGLEPLRNEAGELGFRVLVGGGLGRTPVVGAFINEFLPWQDLLSYLDAILRVYNRY
EEEECCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GRRDNKYKARIKILVKALTPEVFAAKVEAEMAHLRGGQTTLTEAEVQRVSRHFVDPQYKV
CCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHH
LSDQHAELAALDAQHPGFARWRQRNVLAHKKPGYIAVTLSLKPTGVAPGDVTDKQLDAIA
HCCCCHHHHEECCCCCCHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
DLADRYSFGQLRTSHEQNIILADVEQRELFTLWNELRDNGFATPNIGLLTDIICCPGGDF
HHHHHCCHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
CSLANAKSIPIAESIQRRFDDLDYLFDIGELDLNISGCMNACGHHHVGHIGVLGVDKKGE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCEEEEEECCCCCC
EFYQVSLGGSASRDASLGKILGPSFAQEAMPDVIEKLIDVYVEKRTEDERFIDTYQRIGI
EEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
DPFKERVYAANH
CHHHHHHHCCCC
>Mature Secondary Structure
MYVYDDYDQKIIEDRVKQFRDQTRRYLVGELSEEEFRPLRLQNGLYVQRFAPMLRVAVPY
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHCCCEEHHHHHHHHHHHCCC
GQLTSRQARMMAKIARDYDKGYAHISTRQNVQFNWPALEDVPDILAELATVQMHAIQTSG
HHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHEECCC
NCLRNVTTDQFAGVAADELVDPRPWCEIVRQWTTFHPEFAYLPRKFKIAINGSTSDRAAI
CHHHCCCHHHHCCCCHHHCCCCCHHHHHHHHHHCCCCCHHHCCCEEEEEECCCCCCCEEE
EVHDIGLEPLRNEAGELGFRVLVGGGLGRTPVVGAFINEFLPWQDLLSYLDAILRVYNRY
EEEECCCCHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
GRRDNKYKARIKILVKALTPEVFAAKVEAEMAHLRGGQTTLTEAEVQRVSRHFVDPQYKV
CCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHH
LSDQHAELAALDAQHPGFARWRQRNVLAHKKPGYIAVTLSLKPTGVAPGDVTDKQLDAIA
HCCCCHHHHEECCCCCCHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHH
DLADRYSFGQLRTSHEQNIILADVEQRELFTLWNELRDNGFATPNIGLLTDIICCPGGDF
HHHHHCCHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCC
CSLANAKSIPIAESIQRRFDDLDYLFDIGELDLNISGCMNACGHHHVGHIGVLGVDKKGE
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHCCCCCCCEEEEEECCCCCC
EFYQVSLGGSASRDASLGKILGPSFAQEAMPDVIEKLIDVYVEKRTEDERFIDTYQRIGI
EEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
DPFKERVYAANH
CHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]