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The map label for this gene is fabG [C]

Identifier: 66045541

GI number: 66045541

Start: 2674409

End: 2675149

Strand: Reverse

Name: fabG [C]

Synonym: Psyr_2301

Alternate gene names: 66045541

Gene position: 2675149-2674409 (Counterclockwise)

Preceding gene: 66045542

Following gene: 66045540

Centisome position: 43.9

GC content: 59.65

Gene sequence:

>741_bases
ATGAAAAAAATTCTGATCATTGGCGCTACATCAACCATTGCCCATGCCTGCGCCCGACGCTGGGCCACGCAAGGCTGTGA
TTTTTTCCTGGTGGCGCGCAATACGGACAAGCTCGTGAGCAATGCCGCCGACCTCAGGGCTCGCGGTGCCGGACACGTAG
ACACCTATCAAATGGACGTCACGCACTTCTCGGAGCACCCGGCGATGCTGGCTGATTGTCTGGCTGTACTGCAGCAGATC
GATGTCGTGCTTCTGGCTCACGGCACCTTGCCCGATCAGAAGGCCTGCGAGCAGAACGCAGGGCTGGCCGTGCAGGAATT
CATCACCAATGGCGCATCGGTGATTGCCTTGCTGACCGTGTTGGCCAGGCAGTTCGAGGTTCAGCGTTGCGGCACACTGG
CGGTGATTTCCTCGGTCGCGGGCGATCGCGGACGCCCTTCCAATTATCTGTACGGCTCGGCCAAGGCTGCCGTCTCGACG
TTCTGCGACGGGTTACAGGCGCGGATGTTCAAGCTGGGCGTACACGTAGTGACCATAAAACCAGGCTTTGTCGACACGCC
CATGACCCGGGGTCTGCCACTGCCGGCCTGGCTGGTGGCGCAACCGGAAGACGTTGCTGAACGCATCGTCAATGGCATCG
CACGCCAATCAACAAGCCTTTACGCGCCGGGCTTCTGGGCATGGATCATGTGGGTGATTCGCTCGATCCCGCAGCCGTTG
TTCAAAAGGCTCAACCTGTGA

Upstream 100 bases:

>100_bases
TGACCGGCAGCGACTTCCGTCAGGCCTATCCGGTGTGGGAACAACTGGAAGCCCTGCGCGACCCCTCTTTGATGTCCCGC
TTCTGGAAACGAGTGATGTC

Downstream 100 bases:

>100_bases
GCGGCTCGCTGTTGCTGTCCGGATGGCGCTATCGGACAGTGCTTCTGTCGATCGTCGTCTCGGCCATGGGGTATCTGGGT
TTCTCGCTGTGGGGCGGCTG

Product: short chain dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: ORF3 [H]

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MKKILIIGATSTIAHACARRWATQGCDFFLVARNTDKLVSNAADLRARGAGHVDTYQMDVTHFSEHPAMLADCLAVLQQI
DVVLLAHGTLPDQKACEQNAGLAVQEFITNGASVIALLTVLARQFEVQRCGTLAVISSVAGDRGRPSNYLYGSAKAAVST
FCDGLQARMFKLGVHVVTIKPGFVDTPMTRGLPLPAWLVAQPEDVAERIVNGIARQSTSLYAPGFWAWIMWVIRSIPQPL
FKRLNL

Sequences:

>Translated_246_residues
MKKILIIGATSTIAHACARRWATQGCDFFLVARNTDKLVSNAADLRARGAGHVDTYQMDVTHFSEHPAMLADCLAVLQQI
DVVLLAHGTLPDQKACEQNAGLAVQEFITNGASVIALLTVLARQFEVQRCGTLAVISSVAGDRGRPSNYLYGSAKAAVST
FCDGLQARMFKLGVHVVTIKPGFVDTPMTRGLPLPAWLVAQPEDVAERIVNGIARQSTSLYAPGFWAWIMWVIRSIPQPL
FKRLNL
>Mature_246_residues
MKKILIIGATSTIAHACARRWATQGCDFFLVARNTDKLVSNAADLRARGAGHVDTYQMDVTHFSEHPAMLADCLAVLQQI
DVVLLAHGTLPDQKACEQNAGLAVQEFITNGASVIALLTVLARQFEVQRCGTLAVISSVAGDRGRPSNYLYGSAKAAVST
FCDGLQARMFKLGVHVVTIKPGFVDTPMTRGLPLPAWLVAQPEDVAERIVNGIARQSTSLYAPGFWAWIMWVIRSIPQPL
FKRLNL

Specific function: May be involved in the biosynthesis of a heptaene-type antibiotic [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Drosophila melanogaster, GI21358495, Length=262, Percent_Identity=22.9007633587786, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 26759; Mature: 26759

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIIGATSTIAHACARRWATQGCDFFLVARNTDKLVSNAADLRARGAGHVDTYQMDV
CCEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEH
THFSEHPAMLADCLAVLQQIDVVLLAHGTLPDQKACEQNAGLAVQEFITNGASVIALLTV
HHHCCCHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHH
LARQFEVQRCGTLAVISSVAGDRGRPSNYLYGSAKAAVSTFCDGLQARMFKLGVHVVTIK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCEEEEEEC
PGFVDTPMTRGLPLPAWLVAQPEDVAERIVNGIARQSTSLYAPGFWAWIMWVIRSIPQPL
CCCCCCCCCCCCCCCHHEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHH
FKRLNL
HHHCCC
>Mature Secondary Structure
MKKILIIGATSTIAHACARRWATQGCDFFLVARNTDKLVSNAADLRARGAGHVDTYQMDV
CCEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCCCEEEEEEH
THFSEHPAMLADCLAVLQQIDVVLLAHGTLPDQKACEQNAGLAVQEFITNGASVIALLTV
HHHCCCHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHCCCCHHHHHHHCCHHHHHHHHH
LARQFEVQRCGTLAVISSVAGDRGRPSNYLYGSAKAAVSTFCDGLQARMFKLGVHVVTIK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHCEEEEEEC
PGFVDTPMTRGLPLPAWLVAQPEDVAERIVNGIARQSTSLYAPGFWAWIMWVIRSIPQPL
CCCCCCCCCCCCCCCHHEEECCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHH
FKRLNL
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406267 [H]