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The map label for this gene is dprE1 [H]

Identifier: 66045542

GI number: 66045542

Start: 2675146

End: 2676462

Strand: Reverse

Name: dprE1 [H]

Synonym: Psyr_2302

Alternate gene names: 66045542

Gene position: 2676462-2675146 (Counterclockwise)

Preceding gene: 66045543

Following gene: 66045541

Centisome position: 43.92

GC content: 62.79

Gene sequence:

>1317_bases
ATGAGCGGGCCTCTCTATTCCTGGGGTCGCTACCCGCAGGTTGCCCAGCAGGGTCACGAATGTGACTCGATAAAACGCTT
GCCCGCGTACATCTCGCAAACCGTTGCACACCATCACACCAGCCTGCCCTTCGGCAACGGCCGCAGCTACGGCGACAGCT
GTCTGGCCAGCAGCGCTCACGTACTGGACATGCGCGGGCTGGATCGCTTCATTGCTGCCGACTGGCAGCGCGGCGTGGTG
CAACTGGAAGCGGGCATGACACTGTCGCAACTGCTCGCGGCAGCGATCCCGCACGGCTGGTTTCTACCGGTCACGCCTGG
TACACAGTACGTGACGATAGGCGGCGCGCTGGCCAATGATGTACACGGCAAGAACCATCATCGGCGCGGCACCTTTGGCT
GTCATGTCATGCGCTTCGAGCTGATCCGTCATGACCAGCCGCCCATGGTCTGCTCGGCCGTGGACAATCCGCAGTTTTTC
GCCGCCAGCATTGGTGGCCTCGGTCTGACCGGCGTTATCAGTTGGGTCGAGCTGCAACTGATGCCGATCCGCAGCAGCCA
GATCGACAGTACGGCAGTGCGCTTCGCCAATCTGGCGGAGTTCTTTACGCTGTCGCACGAGCTGGATGCGCAGCATGAAT
ACAGCGTGGCCTGGATCGACTGCCTGGCCCGTGGTGCGCATAGCGGCCGCGGGGTCTACATGGTCGGTGACCACGCCCGT
TACGGGTCACTGTCGGTTGAGGCGCGCAATCGCCTGAACGTGCCGTTCACGCCTCCGGTGTCGCTGATCAACAGCCTGTC
CTTGCGTGCGTTCAATTCGCTGTACTGGCACGCGCACTCAGACCTGCCGAGGCCCCGCCGCAGCGCCTGCGAGGCGTTCT
TCTACCCGCTGGATCGAGTGCTGCACTGGAACCGTCTTTATGGTCGCAAGGGGTTTCAGCAATACCAGTGCGTGATTCCC
GAGCACTGTGCACCCCAGGCCATGCAGCTGCTGCTCGATGCCATCGCAGCCTCGGGACAGGGGTCATTCCTCGCAGTCCT
CAAGCGCTGCGGTGACATCGCCTCGCCCGGGCTGCTGTCTTTTCCGATGCAGGGCGCCTCACTGGCACTGGACTTTGCGC
AGACGCGCGATCTGGCCGGCTCACTGTTCCCGCGTCTGGACGCCATTGTCCGTGACGCGGGTGGACGACTGTACCCGGCC
AAGGATGCGCACATGACCGGCAGCGACTTCCGTCAGGCCTATCCGGTGTGGGAACAACTGGAAGCCCTGCGCGACCCCTC
TTTGATGTCCCGCTTCTGGAAACGAGTGATGTCATGA

Upstream 100 bases:

>100_bases
ATCGCGGCGAAATGAACGAGGACCCGGTGGTTTTCGCGATTCGCGACCGGATCAGCCAGGGGATCGGCTTGCTGTTCCTG
CTGGTGTTCTGGGTCGCAGC

Downstream 100 bases:

>100_bases
AAAAAATTCTGATCATTGGCGCTACATCAACCATTGCCCATGCCTGCGCCCGACGCTGGGCCACGCAAGGCTGTGATTTT
TTCCTGGTGGCGCGCAATAC

Product: FAD linked oxidase, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSGPLYSWGRYPQVAQQGHECDSIKRLPAYISQTVAHHHTSLPFGNGRSYGDSCLASSAHVLDMRGLDRFIAADWQRGVV
QLEAGMTLSQLLAAAIPHGWFLPVTPGTQYVTIGGALANDVHGKNHHRRGTFGCHVMRFELIRHDQPPMVCSAVDNPQFF
AASIGGLGLTGVISWVELQLMPIRSSQIDSTAVRFANLAEFFTLSHELDAQHEYSVAWIDCLARGAHSGRGVYMVGDHAR
YGSLSVEARNRLNVPFTPPVSLINSLSLRAFNSLYWHAHSDLPRPRRSACEAFFYPLDRVLHWNRLYGRKGFQQYQCVIP
EHCAPQAMQLLLDAIAASGQGSFLAVLKRCGDIASPGLLSFPMQGASLALDFAQTRDLAGSLFPRLDAIVRDAGGRLYPA
KDAHMTGSDFRQAYPVWEQLEALRDPSLMSRFWKRVMS

Sequences:

>Translated_438_residues
MSGPLYSWGRYPQVAQQGHECDSIKRLPAYISQTVAHHHTSLPFGNGRSYGDSCLASSAHVLDMRGLDRFIAADWQRGVV
QLEAGMTLSQLLAAAIPHGWFLPVTPGTQYVTIGGALANDVHGKNHHRRGTFGCHVMRFELIRHDQPPMVCSAVDNPQFF
AASIGGLGLTGVISWVELQLMPIRSSQIDSTAVRFANLAEFFTLSHELDAQHEYSVAWIDCLARGAHSGRGVYMVGDHAR
YGSLSVEARNRLNVPFTPPVSLINSLSLRAFNSLYWHAHSDLPRPRRSACEAFFYPLDRVLHWNRLYGRKGFQQYQCVIP
EHCAPQAMQLLLDAIAASGQGSFLAVLKRCGDIASPGLLSFPMQGASLALDFAQTRDLAGSLFPRLDAIVRDAGGRLYPA
KDAHMTGSDFRQAYPVWEQLEALRDPSLMSRFWKRVMS
>Mature_437_residues
SGPLYSWGRYPQVAQQGHECDSIKRLPAYISQTVAHHHTSLPFGNGRSYGDSCLASSAHVLDMRGLDRFIAADWQRGVVQ
LEAGMTLSQLLAAAIPHGWFLPVTPGTQYVTIGGALANDVHGKNHHRRGTFGCHVMRFELIRHDQPPMVCSAVDNPQFFA
ASIGGLGLTGVISWVELQLMPIRSSQIDSTAVRFANLAEFFTLSHELDAQHEYSVAWIDCLARGAHSGRGVYMVGDHARY
GSLSVEARNRLNVPFTPPVSLINSLSLRAFNSLYWHAHSDLPRPRRSACEAFFYPLDRVLHWNRLYGRKGFQQYQCVIPE
HCAPQAMQLLLDAIAASGQGSFLAVLKRCGDIASPGLLSFPMQGASLALDFAQTRDLAGSLFPRLDAIVRDAGGRLYPAK
DAHMTGSDFRQAYPVWEQLEALRDPSLMSRFWKRVMS

Specific function: Involved in the epimerization of decaprenylphosphoryl ribose (DPR) to decaprenylphosphoryl arabinose (DPA) a precursor for arabinan synthesis in mycobacterial cell wall biosynthesis. Probably catalyzes the oxidation at C-2 of decaprenylphosphoryl ribose (

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007173
- InterPro:   IPR016166
- InterPro:   IPR016168
- InterPro:   IPR006094 [H]

Pfam domain/function: PF04030 ALO; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 48517; Mature: 48386

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPLYSWGRYPQVAQQGHECDSIKRLPAYISQTVAHHHTSLPFGNGRSYGDSCLASSAH
CCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCC
VLDMRGLDRFIAADWQRGVVQLEAGMTLSQLLAAAIPHGWFLPVTPGTQYVTIGGALAND
EEEHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCCCEEECCCCCCEEEECCHHHHC
VHGKNHHRRGTFGCHVMRFELIRHDQPPMVCSAVDNPQFFAASIGGLGLTGVISWVELQL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHCCCCHHHHHHHHHEEE
MPIRSSQIDSTAVRFANLAEFFTLSHELDAQHEYSVAWIDCLARGAHSGRGVYMVGDHAR
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCC
YGSLSVEARNRLNVPFTPPVSLINSLSLRAFNSLYWHAHSDLPRPRRSACEAFFYPLDRV
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHH
LHWNRLYGRKGFQQYQCVIPEHCAPQAMQLLLDAIAASGQGSFLAVLKRCGDIASPGLLS
HHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEE
FPMQGASLALDFAQTRDLAGSLFPRLDAIVRDAGGRLYPAKDAHMTGSDFRQAYPVWEQL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHH
EALRDPSLMSRFWKRVMS
HHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SGPLYSWGRYPQVAQQGHECDSIKRLPAYISQTVAHHHTSLPFGNGRSYGDSCLASSAH
CCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCC
VLDMRGLDRFIAADWQRGVVQLEAGMTLSQLLAAAIPHGWFLPVTPGTQYVTIGGALAND
EEEHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHCCCCCEEECCCCCCEEEECCHHHHC
VHGKNHHRRGTFGCHVMRFELIRHDQPPMVCSAVDNPQFFAASIGGLGLTGVISWVELQL
CCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEHHHHCCCCHHHHHHHHHEEE
MPIRSSQIDSTAVRFANLAEFFTLSHELDAQHEYSVAWIDCLARGAHSGRGVYMVGDHAR
EECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCC
YGSLSVEARNRLNVPFTPPVSLINSLSLRAFNSLYWHAHSDLPRPRRSACEAFFYPLDRV
CCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHHH
LHWNRLYGRKGFQQYQCVIPEHCAPQAMQLLLDAIAASGQGSFLAVLKRCGDIASPGLLS
HHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCEE
FPMQGASLALDFAQTRDLAGSLFPRLDAIVRDAGGRLYPAKDAHMTGSDFRQAYPVWEQL
CCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCHHHHH
EALRDPSLMSRFWKRVMS
HHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]