Click here to switch to the map view.

The map label for this gene is mcpB [H]

Identifier: 66045460

GI number: 66045460

Start: 2579677

End: 2581617

Strand: Reverse

Name: mcpB [H]

Synonym: Psyr_2220

Alternate gene names: 66045460

Gene position: 2581617-2579677 (Counterclockwise)

Preceding gene: 66045461

Following gene: 66045458

Centisome position: 42.37

GC content: 59.97

Gene sequence:

>1941_bases
ATGAATATCAAACAAAAATTGACGTGGGCGTTCGCAGTCATTGCGTGCTTGCCCATATTAGTCGTCGCCGCCATCGTGGT
CGTGAACCTGCGTGACAAGGCGACCAGTGATTTCGTGGACAGCAGCGCGCGTGAAATTCGCCAGGTCGACAACGCCATGC
AGCTGTTTTTCGACGGCATTACGCAGAACGTCAATTACATCGCGGCGCACCCGCTGATCGCCGGGGCGAGCGACGATTTC
CGCAACTACATGGGCGCTACGCCTCCTCCGCAGTCCGAGAATGACAGGCAGGCGACCGAGCTGTTCGCCAGTATCGCCAA
GGCTCACCCGGCCTACTCCTACGTCTCTTATGGTCTGATCAACGGCAGCTACATCATGACGCCGGAAGACCCGAAAATGA
GCAACTACGACCCGCGTGTGCGGCCGTGGTACAAGACGGCAATGGCCAATGCCGGCAAGACTGTGCGCAGCGATGCCTAT
TACTGGGCCAACGACGATGCTGTACTGGTCAGCACCATCCGGGCGATTCCCAACAAACTGGGCAACCCTGGCGGCGTGGT
CAATATCGACGTATCGCTCAAGCAGCTGACCAACATCGTCAAGCAGATCAAACTGGGCGAAAGCGGCTATCTGATGCTGA
TGGAAAAGAACGGCACGGTGCTGGTCGATCCCAAACAGCCCGAGCACAATTTCAAGAAACTGGGTGAACTGGGCGACGGC
TTCAGCGAGCTGGCGAAAACCGCCAGTGGTCTGGTCGAGGTGACACTCAACGGCGAACGTTACATGGCCAACGTTTACTC
GTCCGAACAACTGGGCTGGAACTTCATCGGCCTGATCAAACAGGACGAAGTGATGGCCTCGGCCACCCGCCTGACCTGGT
TGATCGGCATCATCGCGGCGGTGCTGGCGGTGGTCTTTGCGATTGTCGGTGCCAGTTTTGCCCGCGTTATCGTGCGTCCG
ATCCACAGCGTTTCCAGCGGCCTGGAAGGCATCGCGGGCGGTGAAGGCGATCTGACTCAGAACCTCGCCGTGCGCGGCAA
GGATGAAACCGCGCAACTGGCGGGCTGGTTCAACAAGTTCCTGACCGCGATTCGCAGCCTGATCCAGCACATCGGTCAGG
CCGCCGGGAAGATTCTCGAAGCCTCACACAGCTCGACACGTGTCTCCAACGACATGGCCGAAGCTGCTGGCCGGCAGCGC
GAAGCGGTGGATATGGTCTCCACGGCGTTTCATGAAATGGTCGCCACCTCCAATGAAGTCGCCCGCTCCTGCAGCCAGGC
CGCCGACTCGGCAGACAACGGTCAGCAACAGGCGCGTGAAGGTCAGCGGCAGATCGACGATGCGGTGCGCAGCGTCGACC
AGCTCAGCGAAGAACTCACCCGCTCGGCCAAGGACATGACGCAACTGGAAAAAGACAGCGCAGGCATTCAGTCGATCCTC
AACACCATCCGCTCGATTGCCGAGCAGACCAACCTGCTGGCGCTCAACGCCGCCATCGAGGCAGCACGTGCGGGCGAACA
GGGCCGCGGCTTCGCCGTCGTAGCCGACGAAGTCCGCGCACTGGCCAAACGCACCTCGGACTCGACCGCCGAAATCGACA
GCCTGCTGGGCAACCTGGCCAAACGTACTGCCTCGGTGGCGCAACAGATGCATGCCAGCCTCGACGTGTCGCAGCAGTCG
GTGACCAAGATCGGACAGGCACGCAGCAGCTTCGGGCAAATCCGTGAGTCAGTGGATGTGATTCGCGACATGAACACCCA
GATCGCAACTGCCGCCGAAGAACAGCATCAGGTGGCCGAAGACATCAACCGGCACATCAGCCAGATCCATGGTGATGCGC
AGTTGATCGCTCAACTCTCGGACTCGGCCCGCGCGGATTCCAGAAGTCTGGAGATGCTGTCCAGCGAACTGGACGGCCTG
GTACGCAAGTTCAAGACCTGA

Upstream 100 bases:

>100_bases
GTAGACCATAAGAGCGCCCTTCAGGCCAACGCCTCGGGGCGCAGACTGTACCCATGCAGCGCCCAACACTTGCGGCAGTA
ACGGACATCCCGGAGCTCGA

Downstream 100 bases:

>100_bases
TACCGCGCACACGGAGCGTGAGGAACGATGGGCATCCCCTATCGTGCCCATGCTCCACGCGGGCATGCCGTTCTGGACGC
AGCAGGTGATCTAATCTCCG

Product: histidine kinase, HAMP region:Cache: chemotaxis sensory transducer

Products: NA

Alternate protein names: H3 [H]

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MNIKQKLTWAFAVIACLPILVVAAIVVVNLRDKATSDFVDSSAREIRQVDNAMQLFFDGITQNVNYIAAHPLIAGASDDF
RNYMGATPPPQSENDRQATELFASIAKAHPAYSYVSYGLINGSYIMTPEDPKMSNYDPRVRPWYKTAMANAGKTVRSDAY
YWANDDAVLVSTIRAIPNKLGNPGGVVNIDVSLKQLTNIVKQIKLGESGYLMLMEKNGTVLVDPKQPEHNFKKLGELGDG
FSELAKTASGLVEVTLNGERYMANVYSSEQLGWNFIGLIKQDEVMASATRLTWLIGIIAAVLAVVFAIVGASFARVIVRP
IHSVSSGLEGIAGGEGDLTQNLAVRGKDETAQLAGWFNKFLTAIRSLIQHIGQAAGKILEASHSSTRVSNDMAEAAGRQR
EAVDMVSTAFHEMVATSNEVARSCSQAADSADNGQQQAREGQRQIDDAVRSVDQLSEELTRSAKDMTQLEKDSAGIQSIL
NTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTSDSTAEIDSLLGNLAKRTASVAQQMHASLDVSQQS
VTKIGQARSSFGQIRESVDVIRDMNTQIATAAEEQHQVAEDINRHISQIHGDAQLIAQLSDSARADSRSLEMLSSELDGL
VRKFKT

Sequences:

>Translated_646_residues
MNIKQKLTWAFAVIACLPILVVAAIVVVNLRDKATSDFVDSSAREIRQVDNAMQLFFDGITQNVNYIAAHPLIAGASDDF
RNYMGATPPPQSENDRQATELFASIAKAHPAYSYVSYGLINGSYIMTPEDPKMSNYDPRVRPWYKTAMANAGKTVRSDAY
YWANDDAVLVSTIRAIPNKLGNPGGVVNIDVSLKQLTNIVKQIKLGESGYLMLMEKNGTVLVDPKQPEHNFKKLGELGDG
FSELAKTASGLVEVTLNGERYMANVYSSEQLGWNFIGLIKQDEVMASATRLTWLIGIIAAVLAVVFAIVGASFARVIVRP
IHSVSSGLEGIAGGEGDLTQNLAVRGKDETAQLAGWFNKFLTAIRSLIQHIGQAAGKILEASHSSTRVSNDMAEAAGRQR
EAVDMVSTAFHEMVATSNEVARSCSQAADSADNGQQQAREGQRQIDDAVRSVDQLSEELTRSAKDMTQLEKDSAGIQSIL
NTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTSDSTAEIDSLLGNLAKRTASVAQQMHASLDVSQQS
VTKIGQARSSFGQIRESVDVIRDMNTQIATAAEEQHQVAEDINRHISQIHGDAQLIAQLSDSARADSRSLEMLSSELDGL
VRKFKT
>Mature_646_residues
MNIKQKLTWAFAVIACLPILVVAAIVVVNLRDKATSDFVDSSAREIRQVDNAMQLFFDGITQNVNYIAAHPLIAGASDDF
RNYMGATPPPQSENDRQATELFASIAKAHPAYSYVSYGLINGSYIMTPEDPKMSNYDPRVRPWYKTAMANAGKTVRSDAY
YWANDDAVLVSTIRAIPNKLGNPGGVVNIDVSLKQLTNIVKQIKLGESGYLMLMEKNGTVLVDPKQPEHNFKKLGELGDG
FSELAKTASGLVEVTLNGERYMANVYSSEQLGWNFIGLIKQDEVMASATRLTWLIGIIAAVLAVVFAIVGASFARVIVRP
IHSVSSGLEGIAGGEGDLTQNLAVRGKDETAQLAGWFNKFLTAIRSLIQHIGQAAGKILEASHSSTRVSNDMAEAAGRQR
EAVDMVSTAFHEMVATSNEVARSCSQAADSADNGQQQAREGQRQIDDAVRSVDQLSEELTRSAKDMTQLEKDSAGIQSIL
NTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTSDSTAEIDSLLGNLAKRTASVAQQMHASLDVSQQS
VTKIGQARSSFGQIRESVDVIRDMNTQIATAAEEQHQVAEDINRHISQIHGDAQLIAQLSDSARADSRSLEMLSSELDGL
VRKFKT

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=358, Percent_Identity=29.608938547486, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI2367378, Length=314, Percent_Identity=31.2101910828025, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1788194, Length=330, Percent_Identity=28.1818181818182, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=27.7966101694915, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1789453, Length=310, Percent_Identity=29.3548387096774, Blast_Score=99, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 69931; Mature: 69931

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKQKLTWAFAVIACLPILVVAAIVVVNLRDKATSDFVDSSAREIRQVDNAMQLFFDGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQNVNYIAAHPLIAGASDDFRNYMGATPPPQSENDRQATELFASIAKAHPAYSYVSYGLI
HCCCCCEEECCEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHEE
NGSYIMTPEDPKMSNYDPRVRPWYKTAMANAGKTVRSDAYYWANDDAVLVSTIRAIPNKL
CCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCEEEECCCHHHHHHHHHHHHHC
GNPGGVVNIDVSLKQLTNIVKQIKLGESGYLMLMEKNGTVLVDPKQPEHNFKKLGELGDG
CCCCCEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHCCC
FSELAKTASGLVEVTLNGERYMANVYSSEQLGWNFIGLIKQDEVMASATRLTWLIGIIAA
HHHHHHHHCCEEEEEECCCHHHHHHHCCCCCCCHHEEHCCHHHHHHHHHHHHHHHHHHHH
VLAVVFAIVGASFARVIVRPIHSVSSGLEGIAGGEGDLTQNLAVRGKDETAQLAGWFNKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHH
LTAIRSLIQHIGQAAGKILEASHSSTRVSNDMAEAAGRQREAVDMVSTAFHEMVATSNEV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ARSCSQAADSADNGQQQAREGQRQIDDAVRSVDQLSEELTRSAKDMTQLEKDSAGIQSIL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTSDSTAEIDSLLGNLA
HHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
KRTASVAQQMHASLDVSQQSVTKIGQARSSFGQIRESVDVIRDMNTQIATAAEEQHQVAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DINRHISQIHGDAQLIAQLSDSARADSRSLEMLSSELDGLVRKFKT
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNIKQKLTWAFAVIACLPILVVAAIVVVNLRDKATSDFVDSSAREIRQVDNAMQLFFDGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQNVNYIAAHPLIAGASDDFRNYMGATPPPQSENDRQATELFASIAKAHPAYSYVSYGLI
HCCCCCEEECCEECCCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHEE
NGSYIMTPEDPKMSNYDPRVRPWYKTAMANAGKTVRSDAYYWANDDAVLVSTIRAIPNKL
CCEEEECCCCCCCCCCCCCCCHHHHHHHHHCCCCHHCCCEEEECCCHHHHHHHHHHHHHC
GNPGGVVNIDVSLKQLTNIVKQIKLGESGYLMLMEKNGTVLVDPKQPEHNFKKLGELGDG
CCCCCEEEEECHHHHHHHHHHHHHCCCCCEEEEEECCCEEEECCCCCCHHHHHHHHHCCC
FSELAKTASGLVEVTLNGERYMANVYSSEQLGWNFIGLIKQDEVMASATRLTWLIGIIAA
HHHHHHHHCCEEEEEECCCHHHHHHHCCCCCCCHHEEHCCHHHHHHHHHHHHHHHHHHHH
VLAVVFAIVGASFARVIVRPIHSVSSGLEGIAGGEGDLTQNLAVRGKDETAQLAGWFNKF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHH
LTAIRSLIQHIGQAAGKILEASHSSTRVSNDMAEAAGRQREAVDMVSTAFHEMVATSNEV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ARSCSQAADSADNGQQQAREGQRQIDDAVRSVDQLSEELTRSAKDMTQLEKDSAGIQSIL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NTIRSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAKRTSDSTAEIDSLLGNLA
HHHHHHHHHHCHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
KRTASVAQQMHASLDVSQQSVTKIGQARSSFGQIRESVDVIRDMNTQIATAAEEQHQVAE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
DINRHISQIHGDAQLIAQLSDSARADSRSLEMLSSELDGLVRKFKT
HHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]