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The map label for this gene is dgoR [H]

Identifier: 66044952

GI number: 66044952

Start: 1932068

End: 1932781

Strand: Reverse

Name: dgoR [H]

Synonym: Psyr_1707

Alternate gene names: 66044952

Gene position: 1932781-1932068 (Counterclockwise)

Preceding gene: 66044953

Following gene: 66044948

Centisome position: 31.72

GC content: 61.9

Gene sequence:

>714_bases
ATGGATTATCGAAAGCCTTCCGACCGAAAAAGCATGCACGCCCGTATTGTCCAGGAACTGGGCATGCAAATCGTGTCCGG
CCGTTTCAAGCCTGACGAAAAGCTGCCTGCCGAAGCGATGCTCTGCGAAGAGTATGCCGTCAGCCGCCCGGTCCTGCGTG
AAGCCACGCGGGTTCTGGTGGCCAAGGGTCTGGTTTATTCGCGGCCGCGTGTCGGCACGGTGGTCAAGGCGCGTCGCGAA
TGGCATCTGCTGGACCCGGACGTACTGCACTGGGTCATGCAAAGCTCGCCGCAGAATGATTTCTTCAATCTGCTGACCAG
CGTACGCGCTGTCATCGAACCAGCAGTTGCAGCACTGGCCGCGCAGCATGCCACCGACGCAGAGATCGAGTCGATCCACG
AAGCCTACCTGCGCATGGAAGCCGCACCGACGCCGGAAGACCTGCTGCAACCCGATCTCGACTTCCACAGCCGCATCGCC
GACGCCACCCACAACGACTTGCTGGCTCACCTGTGCAACATGCTGTCACTGGCGTTGCGCGAAGCGCTCAAATACTCCAA
CAAGCGTCCCAACCTGCACGAACTGGCCATGCCGCGTCACAAGGCGATCCTCACCGCCATCCAGAACCGCGACGCGCTGG
GCGCACGCCACGCCTCGCTGGTGCAACTGGACGATGCACGCAACGCGCTGAGTGTGGTGCTCGGCGGAGGCTGA

Upstream 100 bases:

>100_bases
ACTGACCAAAGCGGCGGTTTACCTGACGCAGGCAGCCGCCGCAAGTGTTACGCAATGGTATGATGCCCAGCAATTACCGC
CAGGACCGACCAGCGTTCCC

Downstream 100 bases:

>100_bases
TGGGTTACCAGCGCGAGGATCAACCGTTACAGGCGGCTGACGTTCTCCCCCTCTGGATGCAGCCTATCGCCAGCACGTAC
ATCAACAGGCTGACCAGAAA

Product: transcriptional regulator GntR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MDYRKPSDRKSMHARIVQELGMQIVSGRFKPDEKLPAEAMLCEEYAVSRPVLREATRVLVAKGLVYSRPRVGTVVKARRE
WHLLDPDVLHWVMQSSPQNDFFNLLTSVRAVIEPAVAALAAQHATDAEIESIHEAYLRMEAAPTPEDLLQPDLDFHSRIA
DATHNDLLAHLCNMLSLALREALKYSNKRPNLHELAMPRHKAILTAIQNRDALGARHASLVQLDDARNALSVVLGGG

Sequences:

>Translated_237_residues
MDYRKPSDRKSMHARIVQELGMQIVSGRFKPDEKLPAEAMLCEEYAVSRPVLREATRVLVAKGLVYSRPRVGTVVKARRE
WHLLDPDVLHWVMQSSPQNDFFNLLTSVRAVIEPAVAALAAQHATDAEIESIHEAYLRMEAAPTPEDLLQPDLDFHSRIA
DATHNDLLAHLCNMLSLALREALKYSNKRPNLHELAMPRHKAILTAIQNRDALGARHASLVQLDDARNALSVVLGGG
>Mature_237_residues
MDYRKPSDRKSMHARIVQELGMQIVSGRFKPDEKLPAEAMLCEEYAVSRPVLREATRVLVAKGLVYSRPRVGTVVKARRE
WHLLDPDVLHWVMQSSPQNDFFNLLTSVRAVIEPAVAALAAQHATDAEIESIHEAYLRMEAAPTPEDLLQPDLDFHSRIA
DATHNDLLAHLCNMLSLALREALKYSNKRPNLHELAMPRHKAILTAIQNRDALGARHASLVQLDDARNALSVVLGGG

Specific function: Repressor for the dgoRKAT operon. Binds D-galactonate as an inducer [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994955, Length=212, Percent_Identity=34.4339622641509, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI48994961, Length=215, Percent_Identity=28.3720930232558, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790032, Length=198, Percent_Identity=32.8282828282828, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1786303, Length=211, Percent_Identity=32.2274881516588, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1790780, Length=236, Percent_Identity=28.8135593220339, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26485; Mature: 26485

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRKPSDRKSMHARIVQELGMQIVSGRFKPDEKLPAEAMLCEEYAVSRPVLREATRVLV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
AKGLVYSRPRVGTVVKARREWHLLDPDVLHWVMQSSPQNDFFNLLTSVRAVIEPAVAALA
HHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AQHATDAEIESIHEAYLRMEAAPTPEDLLQPDLDFHSRIADATHNDLLAHLCNMLSLALR
HHHCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALKYSNKRPNLHELAMPRHKAILTAIQNRDALGARHASLVQLDDARNALSVVLGGG
HHHHHCCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCC
>Mature Secondary Structure
MDYRKPSDRKSMHARIVQELGMQIVSGRFKPDEKLPAEAMLCEEYAVSRPVLREATRVLV
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHH
AKGLVYSRPRVGTVVKARREWHLLDPDVLHWVMQSSPQNDFFNLLTSVRAVIEPAVAALA
HHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AQHATDAEIESIHEAYLRMEAAPTPEDLLQPDLDFHSRIADATHNDLLAHLCNMLSLALR
HHHCCHHHHHHHHHHHHHHCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
EALKYSNKRPNLHELAMPRHKAILTAIQNRDALGARHASLVQLDDARNALSVVLGGG
HHHHHCCCCCCHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]