Click here to switch to the map view.

The map label for this gene is thiP [C]

Identifier: 66044849

GI number: 66044849

Start: 1803349

End: 1804191

Strand: Reverse

Name: thiP [C]

Synonym: Psyr_1604

Alternate gene names: 66044849

Gene position: 1804191-1803349 (Counterclockwise)

Preceding gene: 66044850

Following gene: 66044848

Centisome position: 29.61

GC content: 59.55

Gene sequence:

>843_bases
TTGACGACCTTTTCCCGAGGCAAGTGGCTGGGGCTGTTGTGCCTGCTGCCCTTCGCCGTATTTTTCATCGTGTTTCAGAT
CGCACCGCTGTTGTGGGTCGCGATCCACAGCCTGCAAAGCGATGCCGGCTGGGGCTGGGAAAACTTCACCCGGGCGTTCA
GCTCGAAGTTCTATCGGCAGGCCATTCAGTACAGCCTGGAGATCAGCTTCTGGTCGAGCCTGTTCGGCATCATCATCTCC
GTTCTGGGTGCCTATTCACTGCGCAAGGTGGATTCGCGGCTGCGCGATTTCGTCAACTCGTTCGCCAACATGACCAGCAA
TTTCGCCGGCGTTCCACTGGCGTTCGCGTTCATCATCCTGCTGGGGTTCAACGGCGCGCTGACCCTGATCCTCAAGCAGA
CCGGGATCATCGATGACTTCAACCTGTATTCCAAGACCGGACTGATCATCCTTTATACCTACTTCCAGATCCCCCTCGGC
GTGCTGCTGCTCTACCCCGCATTCGATGCCGTGCGCGAAGACTGGAACGAGTCGGCAGCGCTGCTGGGGGCCAGCAGCTA
TCAGTTCTGGCGCTACATCGGCCTGCCGGTGCTGACCCCGGCACTGCTCGGCACCTTCGTCATTCTGCTGGCCAATGCGC
TCGGCGCGTATGCCACGGTCTACGCGCTGACCACCGGCAATTTCAACGTATTGCCCATCCGTATCGCGGCGATGGTCGCG
GGCGATATCACGCTGGACCCGAACATGGCCAGCGCGCTGGCGATGATTCTGGTCGGTCTCATGACCCTGGTCACGGTGGT
CCATCAGTGGCTGTTGAGAAGGAGCTACCATGTCACGCGTTGA

Upstream 100 bases:

>100_bases
TGAATGTCGACGCCGCGCCGCGCCAGACCGATCTGTGCGGCACCGTTTGCGAGCTGCTGGGTATCCCTCACGACAAACCG
GTCTGCCGGGAGATCTTCAA

Downstream 100 bases:

>100_bases
ACGAGGGCCTGCGAGCATTTATCACAAGACGGTGGTCTGCCTGCTGTTCCTGATCCTGTTGCTGCCGCTGGCCGGCACCT
TCCTGTACTCGATCGCGACC

Product: binding-protein dependent transport system inner membrane protein

Products: ADP; phosphate; thiamine [Cytoplasm] [C]

Alternate protein names: ABC Transporter Permease; ABC Transporter; ABC Transporter Membrane Spanning Protein; Transmembrane Component Of ABC Transporter; ABC-Type Transport System Permease Protein; Permease Of ABC Transporter; Polyamine ABC Transporter Permease Protein; Acriflavin Resistance Protein; Permease; Permease BitE; Sulfate ABC Transporter Permease; Spermidine/Putrescine ABC Transporter; Sulfate ABC Transporter Permease Protein; ABC Transporter Membrane Component; ABC Transporter Membrane Protein; Ferric Transport System Permease Protein; ABC-Type Transporter Permease Component; ABC Transport System Permease Protein; ABC-Type Transport System Permease Component; ABC Trasnporter Integral Membrane Subunit; Permease Protein; ABC Transporter, Permease Component Fragment; ABC Transporter Permease Component; ABC Transport System Membrane Protein; Spermidine/Putrescine ABC Transporter Permease Protein; Sulfate ABC Transporter Permease CysT

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MTTFSRGKWLGLLCLLPFAVFFIVFQIAPLLWVAIHSLQSDAGWGWENFTRAFSSKFYRQAIQYSLEISFWSSLFGIIIS
VLGAYSLRKVDSRLRDFVNSFANMTSNFAGVPLAFAFIILLGFNGALTLILKQTGIIDDFNLYSKTGLIILYTYFQIPLG
VLLLYPAFDAVREDWNESAALLGASSYQFWRYIGLPVLTPALLGTFVILLANALGAYATVYALTTGNFNVLPIRIAAMVA
GDITLDPNMASALAMILVGLMTLVTVVHQWLLRRSYHVTR

Sequences:

>Translated_280_residues
MTTFSRGKWLGLLCLLPFAVFFIVFQIAPLLWVAIHSLQSDAGWGWENFTRAFSSKFYRQAIQYSLEISFWSSLFGIIIS
VLGAYSLRKVDSRLRDFVNSFANMTSNFAGVPLAFAFIILLGFNGALTLILKQTGIIDDFNLYSKTGLIILYTYFQIPLG
VLLLYPAFDAVREDWNESAALLGASSYQFWRYIGLPVLTPALLGTFVILLANALGAYATVYALTTGNFNVLPIRIAAMVA
GDITLDPNMASALAMILVGLMTLVTVVHQWLLRRSYHVTR
>Mature_279_residues
TTFSRGKWLGLLCLLPFAVFFIVFQIAPLLWVAIHSLQSDAGWGWENFTRAFSSKFYRQAIQYSLEISFWSSLFGIIISV
LGAYSLRKVDSRLRDFVNSFANMTSNFAGVPLAFAFIILLGFNGALTLILKQTGIIDDFNLYSKTGLIILYTYFQIPLGV
LLLYPAFDAVREDWNESAALLGASSYQFWRYIGLPVLTPALLGTFVILLANALGAYATVYALTTGNFNVLPIRIAAMVAG
DITLDPNMASALAMILVGLMTLVTVVHQWLLRRSYHVTR

Specific function: Part Of The Binding-Protein-Dependent Transport System Tbpa-Thipq For Thiamine And Tpp. Probably Responsible For The Translocation Of The Substrate Across The Membrane. [C]

COG id: COG4132

COG function: function code R; ABC-type uncharacterized transport system, permease component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 31185; Mature: 31054

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTFSRGKWLGLLCLLPFAVFFIVFQIAPLLWVAIHSLQSDAGWGWENFTRAFSSKFYRQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
AIQYSLEISFWSSLFGIIISVLGAYSLRKVDSRLRDFVNSFANMTSNFAGVPLAFAFIIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LGFNGALTLILKQTGIIDDFNLYSKTGLIILYTYFQIPLGVLLLYPAFDAVREDWNESAA
HCCCCHHHHEEHHCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LLGASSYQFWRYIGLPVLTPALLGTFVILLANALGAYATVYALTTGNFNVLPIRIAAMVA
HHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEHHHHHHHHHH
GDITLDPNMASALAMILVGLMTLVTVVHQWLLRRSYHVTR
CCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine [Periplasm]; H2O [C]

Specific reaction: ATP + thiamine [Periplasm] + H2O = ADP + phosphate + thiamine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA